JP2002503334A5 - - Google Patents

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Publication number
JP2002503334A5
JP2002503334A5 JP1998512139A JP51213998A JP2002503334A5 JP 2002503334 A5 JP2002503334 A5 JP 2002503334A5 JP 1998512139 A JP1998512139 A JP 1998512139A JP 51213998 A JP51213998 A JP 51213998A JP 2002503334 A5 JP2002503334 A5 JP 2002503334A5
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JP
Japan
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Ceased
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JP1998512139A
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English (en)
Japanese (ja)
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JP2002503334A (ja
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Priority claimed from PCT/DK1997/000368 external-priority patent/WO1998010267A1/en
Publication of JP2002503334A publication Critical patent/JP2002503334A/ja
Publication of JP2002503334A5 publication Critical patent/JP2002503334A5/ja
Ceased legal-status Critical Current

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JP51213998A 1996-09-04 1997-09-04 粒子の分離と分析用のマイクロフローシステム Ceased JP2002503334A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DK95396 1996-09-04
DK0953/96 1997-02-10
DK15097 1997-02-10
DK0150/97 1997-02-10
PCT/DK1997/000368 WO1998010267A1 (en) 1996-09-04 1997-09-04 A micro flow system for particle separation and analysis

Publications (2)

Publication Number Publication Date
JP2002503334A JP2002503334A (ja) 2002-01-29
JP2002503334A5 true JP2002503334A5 (enExample) 2005-05-12

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JP51213998A Ceased JP2002503334A (ja) 1996-09-04 1997-09-04 粒子の分離と分析用のマイクロフローシステム

Country Status (10)

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US (3) US6432630B1 (enExample)
EP (1) EP0925494B1 (enExample)
JP (1) JP2002503334A (enExample)
AT (1) ATE211258T1 (enExample)
AU (1) AU4113297A (enExample)
CA (1) CA2264389A1 (enExample)
DE (1) DE69709377T2 (enExample)
DK (1) DK0925494T3 (enExample)
NO (1) NO317958B1 (enExample)
WO (1) WO1998010267A1 (enExample)

Families Citing this family (500)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4323571B2 (ja) 1997-01-31 2009-09-02 エックスワイ, インコーポレイテッド 光学装置
US7214298B2 (en) * 1997-09-23 2007-05-08 California Institute Of Technology Microfabricated cell sorter
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
CA2230653A1 (en) 1998-02-27 1999-08-27 The Governors Of The University Of Alberta Microchip based enzymatic analysis
JP2002507750A (ja) * 1998-03-25 2002-03-12 トリオン ダイアグノスティクス アクティー ゼルスカブ 場による粒子操作のためのマイクロシステムおよび方法
DE19815882A1 (de) 1998-04-08 1999-10-14 Fuhr Guenther Verfahren und Vorrichtung zur Manipulierung von Mikropartikeln in Fluidströmungen
AU3771599A (en) 1998-05-18 1999-12-06 University Of Washington Liquid analysis cartridge
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
JP2002528699A (ja) * 1998-05-22 2002-09-03 カリフォルニア インスティチュート オブ テクノロジー 微細製作細胞分類器
DE19847952C2 (de) * 1998-09-01 2000-10-05 Inst Physikalische Hochtech Ev Fluidstromschalter
US6858439B1 (en) * 1999-03-15 2005-02-22 Aviva Biosciences Compositions and methods for separation of moieties on chips
WO2000056444A2 (en) * 1999-03-24 2000-09-28 Torsana Biosensor A/S Spatially directed interaction on a solid surface
US6506609B1 (en) 1999-05-17 2003-01-14 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US6592821B1 (en) * 1999-05-17 2003-07-15 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US6696022B1 (en) * 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
US6613211B1 (en) 1999-08-27 2003-09-02 Aclara Biosciences, Inc. Capillary electrokinesis based cellular assays
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
AU2001232805A1 (en) 2000-01-12 2001-07-24 Ut-Battelle, Llc A microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream
US6323040B1 (en) 2000-02-15 2001-11-27 Ryan S. Raz System for biological specimen preparation
US6537433B1 (en) * 2000-03-10 2003-03-25 Applera Corporation Methods and apparatus for the location and concentration of polar analytes using an alternating electric field
JP4504501B2 (ja) * 2000-03-15 2010-07-14 株式会社東海理化電機製作所 粒子移動/固定装置
US20030186426A1 (en) * 2000-03-15 2003-10-02 The Regents Of The University Of California Multichannel flow cell for interacting single optically trapped, DNA molecules with different chemical species
JP2001281233A (ja) * 2000-03-28 2001-10-10 Inst Of Physical & Chemical Res 水性分配用マイクロチップおよびそれを用いた水性分配方法
US7682837B2 (en) * 2000-05-05 2010-03-23 Board Of Trustees Of Leland Stanford Junior University Devices and methods to form a randomly ordered array of magnetic beads and uses thereof
DE10025699A1 (de) * 2000-05-23 2001-12-06 Merck Patent Gmbh Emulgier- und Trennvorrichtung für flüssige Phasen
US8329118B2 (en) * 2004-09-02 2012-12-11 Honeywell International Inc. Method and apparatus for determining one or more operating parameters for a microfluidic circuit
WO2001096857A2 (en) * 2000-06-14 2001-12-20 Board Of Regents, The University Of Texas System Method and apparatus for combined magnetophoretic and dielectrophoretic manipulation of analyte mixtures
AU2001272012A1 (en) * 2000-06-19 2002-01-02 Arizona Board Of Regents Rapid flow-based immunoassay microchip
GB0016247D0 (en) * 2000-06-30 2000-08-23 Torsana Biosensor Diagnostics Flow cell assemblies and methods of spatially directed interaction between liquids and solid surfaces
EP1309863A1 (en) * 2000-08-08 2003-05-14 Aviva Biosciences Corporation Methods for manipulating moieties in microfluidic systems
EP1365241A2 (en) * 2000-08-21 2003-11-26 Darashkevitch, Oleg Method and device for simultaneous detection of multiple components in a mixture
AU2001284681A1 (en) * 2000-09-11 2002-03-26 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Fluidics system
AU2001297014A1 (en) * 2000-10-10 2002-04-22 Aviva Biosciences Corporation An integrated biochip system for sample preparation and analysis
US6623984B1 (en) * 2000-11-01 2003-09-23 The Cleveland Clinic Foundation MEMS-based integrated magnetic particle identification system
FR2817343B1 (fr) * 2000-11-29 2003-05-09 Commissariat Energie Atomique Procede et dispositifs de transport et de concentration d'un analyte present dans un echantillon
AU2002220018A1 (en) 2000-11-29 2002-06-11 Colorado State University System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US6736978B1 (en) * 2000-12-13 2004-05-18 Iowa State University Research Foundation, Inc. Method and apparatus for magnetoresistive monitoring of analytes in flow streams
US6913697B2 (en) 2001-02-14 2005-07-05 Science & Technology Corporation @ Unm Nanostructured separation and analysis devices for biological membranes
CN100494360C (zh) * 2001-03-22 2009-06-03 博奥生物有限公司 细胞分离方法及其应用
JP3538777B2 (ja) * 2001-03-26 2004-06-14 独立行政法人産業技術総合研究所 微小化学反応装置
WO2002081729A2 (en) 2001-04-06 2002-10-17 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
FR2826882B1 (fr) * 2001-07-09 2003-09-12 Bio Merieux Procede de traitement de particules magnetiques et configurations d'aimants permettant la mise en oeuvre de ce procede
EP1409989B1 (en) * 2001-07-13 2010-04-28 Caliper Life Sciences, Inc. Method for separating components of a mixture
US20030110840A1 (en) * 2001-07-24 2003-06-19 Arriaga Edgar A. Systems and methods for detecting a particle
US20030095897A1 (en) * 2001-08-31 2003-05-22 Grate Jay W. Flow-controlled magnetic particle manipulation
US20050148085A1 (en) * 2001-09-16 2005-07-07 Chemometec A/S Method and a system for detecting and optinally isolating a rare event particle
GB0126281D0 (en) * 2001-11-01 2002-01-02 Astrazeneca Ab A chemical reactor
US20040214314A1 (en) * 2001-11-02 2004-10-28 Friedrich Srienc High throughput bioreactor
JP2005509883A (ja) * 2001-11-15 2005-04-14 アリックス,インコーポレーテッド 試料チップ
US20030186465A1 (en) * 2001-11-27 2003-10-02 Kraus Robert H. Apparatus used in identification, sorting and collection methods using magnetic microspheres and magnetic microsphere kits
US7232691B2 (en) * 2001-11-27 2007-06-19 Los Alamos National Security, Llc Bioassay and biomolecular identification, sorting, and collection methods using magnetic microspheres
JP4355210B2 (ja) 2001-11-30 2009-10-28 フルイディグム コーポレイション 微小流体デバイスおよび微小流体デバイスの使用方法
US7252987B2 (en) * 2001-12-06 2007-08-07 Islet Technology, Inc. System for analysis and selection of encapsulated cellular materials
GB0129374D0 (en) * 2001-12-07 2002-01-30 Univ Brunel Test apparatus
EP1335198B1 (de) * 2002-02-01 2004-03-03 Leister Process Technologies Mikrofluidisches Bauelement und Verfahren für die Sortierung von Partikeln in einem Fluid
AU2003216175A1 (en) * 2002-02-04 2003-09-02 Colorado School Of Mines Laminar flow-based separations of colloidal and cellular particles
EP1478739A1 (en) 2002-02-27 2004-11-24 The Regents of the University of Michigan Process for sorting motile particles from lesser-motile particles and apparatus suitable therefor
US7223371B2 (en) * 2002-03-14 2007-05-29 Micronics, Inc. Microfluidic channel network device
JP2004000144A (ja) * 2002-03-29 2004-01-08 Aisin Seiki Co Ltd 細胞分離選別装置、細胞整列用基板
US7312085B2 (en) 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
CA2480728A1 (en) 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
FI118611B (fi) * 2002-04-15 2008-01-15 Labmaster Oy Eriste-elektrodilaitteet
US6808075B2 (en) 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
US7157274B2 (en) * 2002-06-24 2007-01-02 Cytonome, Inc. Method and apparatus for sorting particles
US6877528B2 (en) 2002-04-17 2005-04-12 Cytonome, Inc. Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
KR100975438B1 (ko) * 2002-04-17 2010-08-11 사이토놈/에스티, 엘엘씨 입자 분류 방법 및 장치
US6976590B2 (en) 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
US20070065808A1 (en) * 2002-04-17 2007-03-22 Cytonome, Inc. Method and apparatus for sorting particles
EP1507591A1 (de) * 2002-05-24 2005-02-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum überführen von molekülen aus einem chemisch reagierenden ersten strom in einen benachbarten chemisch reagierenden zweiten strom
JP2006507921A (ja) * 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
US20040018611A1 (en) * 2002-07-23 2004-01-29 Ward Michael Dennis Microfluidic devices for high gradient magnetic separation
US7699767B2 (en) 2002-07-31 2010-04-20 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
JP4057967B2 (ja) * 2002-07-31 2008-03-05 株式会社東芝 塩基配列自動解析装置
US7745203B2 (en) 2002-07-31 2010-06-29 Kabushiki Kaisha Toshiba Base sequence detection apparatus and base sequence automatic analyzing apparatus
US7118676B2 (en) * 2003-09-04 2006-10-10 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
CN1774623B (zh) 2002-07-31 2012-02-01 阿尔利克斯公司 利用全息激光控制分类物质的系统和方法
WO2004012837A2 (en) 2002-08-01 2004-02-12 Xy, Inc. Low pressure sperm cell separation system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
WO2004017041A2 (en) 2002-08-15 2004-02-26 Xy, Inc. High resolution flow cytometer
JP3898103B2 (ja) * 2002-08-26 2007-03-28 独立行政法人科学技術振興機構 細胞分析分離装置
CA2501965C (en) 2002-09-11 2012-04-10 The Regents Of The University Of Michigan Ultrafiltration membrane, device, bioartificial organ, and methods
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
AU2003270722A1 (en) * 2002-09-16 2004-04-30 Cytonome/St, Llc Method and apparatus for sorting particles
AU2003282875A1 (en) 2002-09-25 2004-04-19 California Institute Of Technology Microfluidic large scale integration
WO2004029221A2 (en) 2002-09-27 2004-04-08 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US8871446B2 (en) 2002-10-02 2014-10-28 California Institute Of Technology Microfluidic nucleic acid analysis
EP1553176A4 (en) 2002-10-16 2008-10-01 Universal Bio Research Co Ltd DEVICE FOR INTRODUCING BIOLOGICAL MATERIAL, METHOD FOR INTRODUCING BIOLOGICAL MATERIAL AND MAGNETIC SUPPORT FOR INTRODUCING BIOLOGICAL MATERIAL
EP1420251B1 (en) * 2002-11-12 2013-01-09 Panasonic Corporation Specific coupling reaction measuring method
WO2004061446A1 (en) 2002-12-18 2004-07-22 Aclara Biosciences, Inc. Single cell analysis of membrane molecules
WO2004068553A2 (en) * 2003-01-29 2004-08-12 The Regents Of The University Of Michigan Method for forming nanoscale features
US20050064137A1 (en) * 2003-01-29 2005-03-24 Hunt Alan J. Method for forming nanoscale features and structures produced thereby
US7190450B2 (en) * 2003-02-20 2007-03-13 Yale University Systems and methods for sorting aerosols
US20040171091A1 (en) * 2003-02-27 2004-09-02 Cell Work, Inc. Standardized evaluation of therapeutic efficacy based on cellular biomarkers
WO2004078639A1 (ja) * 2003-03-07 2004-09-16 Tosoh Corporation 微小流路構造体、及び金型
EP1622691B1 (en) 2003-03-14 2011-05-25 The Trustees of Columbia University in the City of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
US20060076295A1 (en) 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
DE10311716A1 (de) 2003-03-17 2004-10-14 Evotec Oai Ag Verfahren und Vorrichtung zur Trennung von Partikeln in einer Flüssigkeitsströmung
DK2305172T3 (en) 2003-03-28 2016-08-22 Inguran Llc DEVICE AND PROCEDURES TO PROVIDE SEXUAL ANIMAL SEED
US20060078893A1 (en) * 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
WO2004091795A2 (en) * 2003-04-10 2004-10-28 U.S. Genomics, Inc. Manipulation of polymers in a microchannel
CA2784762A1 (en) 2003-04-10 2004-10-28 President And Fellows Of Harvard College Formation and control of fluidic species
EP1620862B1 (en) 2003-05-08 2015-07-08 The University Court of the University of St. Andrews Fractionation of particles
DE10320869A1 (de) * 2003-05-09 2004-12-16 Evotec Technologies Gmbh Verfahren und Vorrichtungen zur Flüssigkeitsbehandlung suspendierter Partikel
JP3711988B2 (ja) * 2003-05-12 2005-11-02 株式会社日立製作所 微粒子アレー分析システム、微粒子アレーキットおよび化学分析方法
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
CA2514115A1 (en) * 2003-05-19 2004-11-25 Japan Science And Technology Agency Cell separation apparatus
GB0313197D0 (en) * 2003-06-09 2003-07-16 Imp College Innovations Ltd Free flow electrophoresis microchip, system and method
WO2004113491A1 (ja) * 2003-06-20 2004-12-29 Nitto Denko Corporation 細胞マイクロチップ
DE602004016004D1 (de) * 2003-08-26 2008-10-02 Univ Danmarks Tekniske Kontinuierliches verfahren zur anordnung von makromolekulären substanzen und die anschliessende aufnahme und isolierung einer makromolekulären anordnung, sowie ein für dieses verfahren geeignetes system
CN1842368B (zh) * 2003-08-27 2014-05-28 哈佛大学 流体物种的电子控制
JP4533382B2 (ja) 2003-08-28 2010-09-01 セルラ・インコーポレイテッド マイクロ流体分析およびソーティング用の一体化された構造物
EP1663460B1 (en) * 2003-09-04 2015-07-08 Premium Genetics (UK) Limited Multiple laminar flow-based particle and cellular separation with laser steering
FR2860006B1 (fr) * 2003-09-24 2006-12-22 Commissariat Energie Atomique Dispositif pour separer et/ou analyser plusieurs cibles moleculaires en solution dans un melange complexe
JP3787578B2 (ja) * 2003-10-29 2006-06-21 アイダエンジニアリング株式会社 マイクロチップの微細流路における液体送液方法
FR2863626B1 (fr) * 2003-12-15 2006-08-04 Commissariat Energie Atomique Procede et dispositif de division d'un echantillon biologique par effet magnetique
WO2005069015A1 (ja) 2004-01-15 2005-07-28 Japan Science And Technology Agency 化学分析装置及び化学分析方法
US20050178700A1 (en) * 2004-01-21 2005-08-18 David Tyvoll Sorting particles in parallel
US20060121624A1 (en) * 2004-03-03 2006-06-08 Huang Lotien R Methods and systems for fluid delivery
WO2005084380A2 (en) * 2004-03-03 2005-09-15 The General Hospital Corporation System for delivering a diluted solution
US8058056B2 (en) * 2004-03-12 2011-11-15 The Regents Of The University Of California Method and apparatus for integrated cell handling and measurements
US20050205483A1 (en) * 2004-03-22 2005-09-22 Birmingham Joseph G Microimpactor system for collection of particles from a fluid stream
US7258716B2 (en) * 2004-03-22 2007-08-21 Joseph Gerard Birmingham Microimpactor system having optimized impactor spacing
JP4643921B2 (ja) * 2004-03-26 2011-03-02 独立行政法人科学技術振興機構 流路における流体の通過を検出する方法および流体の流れを制御する方法
BRPI0509485A (pt) 2004-03-29 2007-09-11 Monsanto Technology Llc suspensões de esperma para uso em inseminação
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
JP2006010529A (ja) * 2004-06-25 2006-01-12 Canon Inc 磁性粒子分離装置および分離方法
JP2006010535A (ja) * 2004-06-25 2006-01-12 Canon Inc 標的物質捕捉方法および装置
JP2006007146A (ja) * 2004-06-28 2006-01-12 Canon Inc 粒子分離装置
US9477233B2 (en) 2004-07-02 2016-10-25 The University Of Chicago Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets
US7655470B2 (en) 2004-10-29 2010-02-02 University Of Chicago Method for manipulating a plurality of plugs and performing reactions therein in microfluidic systems
ITBO20040420A1 (it) 2004-07-07 2004-10-07 Type S R L Macchina per taglio e formatura di piattine metalliche
MX2007000888A (es) 2004-07-22 2007-04-02 Monsanto Technology Llc Procedimiento para enriquecer una poblacion de celulas de esperma.
US7156365B2 (en) * 2004-07-27 2007-01-02 Kelsey-Hayes Company Method of controlling microvalve actuator
US7340957B2 (en) 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
US7595170B2 (en) * 2004-08-05 2009-09-29 Modrovich Ivan E Apparatus and method for measuring concentrations of molecules through a barrier
DE102004040785B4 (de) * 2004-08-23 2006-09-21 Kist-Europe Forschungsgesellschaft Mbh Mikrofluidisches System zur Isolierung biologischer Partikel unter Verwendung der immunomagnetischen Separation
JP2006087336A (ja) * 2004-09-22 2006-04-06 Shimadzu Corp 細胞分析装置
ITBO20040601A1 (it) * 2004-09-30 2004-12-30 Ima Spa Metodo per il controllo di capsule
DE102004047953A1 (de) * 2004-10-01 2006-04-20 Rudolf Rigler Selektion von Partikeln im laminaren Fluss
DE102004048443B3 (de) * 2004-10-02 2005-12-01 C.D. Wälzholz-Brockhaus GmbH Verfahren zur walztechnischen Verformung von draht- und stabförmigem Vormaterial, Vorrichtung zur Durchführung des Verfahrens sowie nach dem Verfahren hergestelltes Flachprofil
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US7534097B2 (en) * 2004-10-15 2009-05-19 Nanyang Technological University Method and apparatus for controlling multi-fluid flow in a micro channel
DE102004055662A1 (de) * 2004-11-18 2006-06-01 Evotec Technologies Gmbh Mikrofluidisches System mit einer Kanalaufweitung
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
JP4601423B2 (ja) * 2004-12-28 2010-12-22 独立行政法人科学技術振興機構 細胞計測および分離チップ
US20060171846A1 (en) * 2005-01-10 2006-08-03 Marr David W M Microfluidic systems incorporating integrated optical waveguides
US20060252087A1 (en) * 2005-01-18 2006-11-09 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
US20090136982A1 (en) 2005-01-18 2009-05-28 Biocept, Inc. Cell separation using microchannel having patterned posts
US8158410B2 (en) 2005-01-18 2012-04-17 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
ES2437845T3 (es) 2005-01-18 2014-01-14 Biocept, Inc. Separación de células usando un microcanal que tiene pilares con una configuración
JP4047336B2 (ja) * 2005-02-08 2008-02-13 独立行政法人科学技術振興機構 ゲル電極付セルソーターチップ
US20070054119A1 (en) * 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
EP1861194A2 (en) 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
FR2882939B1 (fr) * 2005-03-11 2007-06-08 Centre Nat Rech Scient Dispositif de separation fluidique
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US20060223178A1 (en) * 2005-04-05 2006-10-05 Tom Barber Devices and methods for magnetic enrichment of cells and other particles
EP2594631A1 (en) * 2005-04-05 2013-05-22 Cellpoint Diagnostics Devices and method for detecting circulating tumor cells and other particles
DE112005003572T5 (de) * 2005-05-13 2008-03-27 Agilent Technologies Inc., Santa Clara Flusszelle mit Hüllfluss
WO2006128098A2 (en) * 2005-05-27 2006-11-30 Applera Corporation Cytometric system including nucleic acid sequence amplification, and method
US20090317798A1 (en) * 2005-06-02 2009-12-24 Heid Christian A Analysis using microfluidic partitioning devices
EP3257949A1 (en) 2005-06-15 2017-12-20 Complete Genomics Inc. Nucleic acid analysis by random mixtures of non-overlapping fragments
CA2552456A1 (en) * 2005-07-18 2007-01-18 Barry Ruddick Apparatus, system and method for evaluating fluid systems
US20070128083A1 (en) * 2005-07-18 2007-06-07 U.S. Genomics, Inc. Microfluidic methods and apparatuses for sample preparation and analysis
ITBO20050481A1 (it) 2005-07-19 2007-01-20 Silicon Biosystems S R L Metodo ed apparato per la manipolazione e/o l'individuazione di particelle
US20070025879A1 (en) * 2005-07-27 2007-02-01 Dakocytomation Denmark A/S Method and apparatus for syringe-based sample introduction within a flow cytometer
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20090201504A1 (en) * 2005-08-09 2009-08-13 Maxwell Sensors, Inc. Hydrodynamic focusing for analyzing rectangular microbeads
US7858307B2 (en) 2005-08-09 2010-12-28 Maxwell Sensors, Inc. Light transmitted assay beads
US8232092B2 (en) * 2005-08-09 2012-07-31 Maxwell Sensors, Inc. Apparatus and method for digital magnetic beads analysis
DE102005039175A1 (de) * 2005-08-18 2007-02-22 Qiagen Gmbh Vorrichtung und Verfahren zum Abtrennen von magnetischen Partikeln aus einer Flüssigkeit
WO2007024778A2 (en) * 2005-08-22 2007-03-01 Applera Corporation Device, system and method for depositing processed immiscible-fluid-discrete-volumes
JP4745755B2 (ja) * 2005-08-23 2011-08-10 セイコーインスツル株式会社 分画マイクロチップ及び分画装置
US20070059782A1 (en) * 2005-09-13 2007-03-15 Graham Henry A Magnetic particle tagged blood bank reagents and techniques
US9488665B2 (en) * 2005-09-13 2016-11-08 Chrome Red Technologies, Llc Magnetic particle tagged reagents and techniques
CA2622745A1 (en) * 2005-09-15 2007-03-29 Artemis Health, Inc. Systems and methods for enrichment of analytes
JP4692200B2 (ja) * 2005-10-06 2011-06-01 横河電機株式会社 化学処理用カートリッジおよびその使用方法
US9220831B2 (en) * 2005-10-06 2015-12-29 Children's Medical Center Corporation Device and method for combined microfluidic-micromagnetic separation of material in continuous flow
ITBO20050646A1 (it) * 2005-10-26 2007-04-27 Silicon Biosystem S R L Metodo ed apparato per la caratterizzazione ed il conteggio di particelle
WO2007056560A2 (en) * 2005-11-09 2007-05-18 Chemimage Corporation System and method for cytological analysis by raman spectroscopic imaging
US7540206B2 (en) * 2005-11-14 2009-06-02 Parker-Hannifin Corporation Self-cleaning sample extraction system
US20080193919A1 (en) * 2005-11-30 2008-08-14 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems and methods for receiving pathogen related information and responding
US20080179255A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic devices
US20080178692A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US20080241909A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for pathogen detection
US20080241910A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for pathogen detection
US20080103746A1 (en) * 2005-11-30 2008-05-01 Searete Llc, A Limited Liability Corporation Systems and methods for pathogen detection and response
US20080241000A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for pathogen detection
US9885644B2 (en) 2006-01-10 2018-02-06 Colorado School Of Mines Dynamic viscoelasticity as a rapid single-cell biomarker
US9878326B2 (en) 2007-09-26 2018-01-30 Colorado School Of Mines Fiber-focused diode-bar optical trapping for microfluidic manipulation
US8119976B2 (en) * 2007-07-03 2012-02-21 Colorado School Of Mines Optical-based cell deformability
US9487812B2 (en) 2012-02-17 2016-11-08 Colorado School Of Mines Optical alignment deformation spectroscopy
AU2006335290A1 (en) * 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
US7695956B2 (en) * 2006-01-12 2010-04-13 Biocept, Inc. Device for cell separation and analysis and method of using
CN101004423B (zh) * 2006-01-19 2011-12-28 博奥生物有限公司 流体样品分析用卡盒系统
JP5000666B2 (ja) * 2006-01-25 2012-08-15 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 流体を分析する装置
WO2007085300A1 (en) * 2006-01-26 2007-08-02 Ecole Polytechnique Federale De Lausanne (Epfl) Magnetic bead retention apparatus and method
DE602007009811D1 (de) * 2006-01-27 2010-11-25 Harvard College Koaleszenz fluider tröpfchen
KR100787234B1 (ko) * 2006-02-17 2007-12-21 한국기계연구원 입자 분리 장치 및 입자 분리 방법
US11237171B2 (en) 2006-02-21 2022-02-01 Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US8492098B2 (en) 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
ITTO20060226A1 (it) 2006-03-27 2007-09-28 Silicon Biosystem S P A Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche
US8293524B2 (en) * 2006-03-31 2012-10-23 Fluxion Biosciences Inc. Methods and apparatus for the manipulation of particle suspensions and testing thereof
WO2007114794A1 (en) * 2006-03-31 2007-10-11 Nam Trung Nguyen Active control for droplet-based microfluidics
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP4190448A3 (en) * 2006-05-11 2023-09-20 Bio-Rad Laboratories, Inc. Microfluidic devices
EP1854543B1 (en) * 2006-05-11 2011-04-06 Corning Incorporated Modular mounting and connection or interconnection system for microfluidic devices
JP5032792B2 (ja) * 2006-05-22 2012-09-26 浜松ホトニクス株式会社 細胞選別装置
MX2008014732A (es) * 2006-05-22 2009-04-07 Univ Columbia Sistemas y metodos de intercambio sin membrana microfluidica usando filtracion de corrientes de salida de fluidos de extraccion.
WO2008016414A2 (en) * 2006-06-01 2008-02-07 The Trustees Of Princeton University Apparatus and method for continuous particle separation
US8296088B2 (en) * 2006-06-02 2012-10-23 Luminex Corporation Systems and methods for performing measurements of one or more materials
WO2007147074A2 (en) 2006-06-14 2007-12-21 Living Microsystems, Inc. Use of highly parallel snp genotyping for fetal diagnosis
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
US20080124721A1 (en) * 2006-06-14 2008-05-29 Martin Fuchs Analysis of rare cell-enriched samples
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
EP2589668A1 (en) 2006-06-14 2013-05-08 Verinata Health, Inc Rare cell analysis using sample splitting and DNA tags
GB0612825D0 (en) * 2006-06-28 2006-08-09 Iti Scotland Ltd Analyte detection
GB0614297D0 (en) * 2006-07-19 2006-08-30 Shaw Water Engineering Ltd Apparatus, system and method for detecting particles
KR100846491B1 (ko) 2006-07-25 2008-07-17 삼성전자주식회사 미세유동 장치 내에서 표적 생체분자의 분리 및 정제를 위한 자성 비드 추출 장치
EP3536396B1 (en) 2006-08-07 2022-03-30 The President and Fellows of Harvard College Fluorocarbon emulsion stabilizing surfactants
GB0616508D0 (en) * 2006-08-18 2006-09-27 Iti Scotland Ltd Analyte manipulation and detection
CN101224402B (zh) 2006-09-01 2012-06-27 东曹株式会社 微小流路结构及采用它的微小颗粒制造方法
GB0618605D0 (en) 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
GB0618606D0 (en) 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
US7807454B2 (en) * 2006-10-18 2010-10-05 The Regents Of The University Of California Microfluidic magnetophoretic device and methods for using the same
US20120122731A1 (en) * 2006-10-18 2012-05-17 Hyongsok Soh Screening molecular libraries using microfluidic devices
JP4984849B2 (ja) * 2006-11-27 2012-07-25 パナソニック株式会社 成分分離デバイスと、この成分分離デバイスを用いた化学分析デバイス
CA2580589C (en) * 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
US8999636B2 (en) 2007-01-08 2015-04-07 Toxic Report Llc Reaction chamber
US9403126B2 (en) 2007-01-10 2016-08-02 The Regents Of The University Of Michigan Ultrafiltration membrane, device, bioartificial organ, and related methods
GB0701641D0 (en) * 2007-01-29 2007-03-07 Iti Scotland Ltd Analyte manipulation and detection
US20080181821A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for allergen detection
US10001496B2 (en) 2007-01-29 2018-06-19 Gearbox, Llc Systems for allergen detection
US20090050569A1 (en) * 2007-01-29 2009-02-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US20080180259A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for allergen detection
US20080245740A1 (en) * 2007-01-29 2008-10-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US8617903B2 (en) * 2007-01-29 2013-12-31 The Invention Science Fund I, Llc Methods for allergen detection
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US20100108578A1 (en) * 2007-02-07 2010-05-06 Koninklijke Philips Electronics N.V. Means for the separation of magnetic particles
US20090081750A1 (en) * 2007-02-14 2009-03-26 Bio-Rad Laboratories, Inc. Transfection in magnetically driven continuous flow
US20090227005A1 (en) * 2007-03-27 2009-09-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods for pathogen detection
US7776927B2 (en) * 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
US20080237044A1 (en) * 2007-03-28 2008-10-02 The Charles Stark Draper Laboratory, Inc. Method and apparatus for concentrating molecules
EP2156178B1 (en) * 2007-04-02 2011-12-21 Acoustic Cytometry Systems, Inc. Methods for enhanced analysis of acoustic field focused cells and particles
CN103630470B (zh) 2007-04-16 2016-03-16 通用医疗公司以马萨诸塞州通用医疗公司名义经营 使粒子在微通道中聚集的系统和方法
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
US8292083B2 (en) * 2007-04-19 2012-10-23 The Charles Stark Draper Laboratory, Inc. Method and apparatus for separating particles, cells, molecules and particulates
US8691164B2 (en) * 2007-04-20 2014-04-08 Celula, Inc. Cell sorting system and methods
US9110010B2 (en) * 2007-05-11 2015-08-18 The United States Of America, As Represented By The Secretary Of The Navy Electrical detection using confined fluids
EP2150350B1 (en) * 2007-05-24 2012-04-25 The Regents of the University of California Integrated fluidics devices with magnetic sorting
WO2009006456A1 (en) 2007-06-29 2009-01-08 The Trustees Of Columbia University Microfluidic device for counting biological particles
US8921121B2 (en) * 2007-06-29 2014-12-30 The Trustees Of Columbia University In The City Of New York Methods, devices, and systems for chemiluminescence-based microfluidic cell counting
US20110290330A1 (en) * 2007-08-09 2011-12-01 Agilent Technologies, Inc. Fluid flow control in a microfluidic device
EP2178641B1 (en) * 2007-08-09 2018-04-11 Progenity, Inc. Methods and devices for correlated, multi-parameter single cell measurements and recovery of remnant biological material
ITBO20070588A1 (it) 2007-08-13 2009-02-14 Silicon Biosystems Spa Metodo per legare uno strato di silicone ad un substrato di polimero metacrilico
CN101842161A (zh) * 2007-08-23 2010-09-22 辛温尼奥生物系统公司 用于目标物质的俘获磁性拣选系统
EP2201374B1 (en) 2007-08-30 2015-10-07 Trustees Of Tufts College Methods for determining the concentration of an analyte in solution.
US10722250B2 (en) 2007-09-04 2020-07-28 Colorado School Of Mines Magnetic-field driven colloidal microbots, methods for forming and using the same
US20090062828A1 (en) * 2007-09-04 2009-03-05 Colorado School Of Mines Magnetic field-based colloidal atherectomy
US8835184B2 (en) * 2007-09-14 2014-09-16 Biosensia Patents Limited Analysis system
CN101889192B (zh) * 2007-10-25 2012-07-04 纽约州立大学研究基金会 光子光谱仪
ITTO20070771A1 (it) 2007-10-29 2009-04-30 Silicon Biosystems Spa Metodo e apparato per la identificazione e manipolazione di particelle
BRPI0819296A2 (pt) * 2007-11-22 2015-05-12 Koninkl Philips Electronics Nv Cartucho de sensor, sensor, métodos para fabricar um cartucho de sensor e para determinar frações alvo em uma amostra de fluido, uso de um cartucho de sensor, dispositivo descartável, e, dispositivo leitor
KR101338349B1 (ko) * 2007-11-30 2013-12-06 연세대학교 산학협력단 미세입자 분리 장치 및 이의 제작 방법
US9656271B2 (en) * 2007-12-04 2017-05-23 Headway Technologies, Inc. Guided transport of magnetically labeled biological molecules and cells
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
KR100907213B1 (ko) 2007-12-07 2009-07-10 한국과학기술원 등자기영동 기술을 이용한 미세입자 분리 장치 및등자기영동 기술을 이용한 미세입자 분리 방법
US8071395B2 (en) * 2007-12-12 2011-12-06 The Board Of Trustees Of The Leland Stanford Junior University Methods and apparatus for magnetic separation of cells
US8266951B2 (en) 2007-12-19 2012-09-18 Los Alamos National Security, Llc Particle analysis in an acoustic cytometer
KR101384142B1 (ko) * 2007-12-28 2014-04-14 삼성디스플레이 주식회사 표시기판, 이의 제조방법 및 이를 갖는 표시장치
US8001855B2 (en) * 2008-01-14 2011-08-23 Medi Medical Engineering Corp. Fluid transferring apparatus
JP2009168650A (ja) * 2008-01-17 2009-07-30 Sekisui Chem Co Ltd カートリッジ式電気化学分析装置及び方法
US8496606B2 (en) 2008-02-04 2013-07-30 The Trustees Of Columbia University In The City Of New York Fluid separation devices, systems and methods
KR100965399B1 (ko) 2008-02-14 2010-06-24 연세대학교 산학협력단 전자석의 주울열을 이용하여 채널내 세포의 최적온도조절이 가능한 자성세포분리장치
NL2001322C2 (nl) * 2008-02-27 2009-08-31 Univ Delft Tech Werkwijze en inrichting voor het scheiden van vaste deeltjes met een onderling dichtheidsverschil.
WO2009117611A2 (en) * 2008-03-19 2009-09-24 Cynvenio Biosystems, Llc Trapping magnetic cell sorting system
US20110137018A1 (en) * 2008-04-16 2011-06-09 Cynvenio Biosystems, Inc. Magnetic separation system with pre and post processing modules
WO2009132151A2 (en) * 2008-04-23 2009-10-29 The Regents Of The University Of California Microfluidic devices and methods of using same
JP4661942B2 (ja) 2008-05-13 2011-03-30 ソニー株式会社 マイクロチップとその流路構造
JP4572973B2 (ja) * 2008-06-16 2010-11-04 ソニー株式会社 マイクロチップ及びマイクロチップにおける送流方法
GB0812781D0 (en) * 2008-07-11 2008-08-20 Deltadot Ltd Material separation device
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
EP4047367A1 (en) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Method for detecting target analytes with droplet libraries
US9180453B2 (en) * 2008-08-15 2015-11-10 University Of Washington Method and apparatus for the discretization and manipulation of sample volumes
ES2620294T3 (es) 2008-09-20 2017-06-28 The Board Of Trustees Of The Leland Stanford Junior University Diagnóstico no invasivo de la aneuploidia fetal por secuenciación
US8222047B2 (en) * 2008-09-23 2012-07-17 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays
US8361716B2 (en) 2008-10-03 2013-01-29 Pathogenetix, Inc. Focusing chamber
EP2346607A2 (en) * 2008-10-10 2011-07-27 Cnrs-Dae Microfluidic integrated device for sample processing
IT1391619B1 (it) 2008-11-04 2012-01-11 Silicon Biosystems Spa Metodo per l'individuazione, selezione e analisi di cellule tumorali
US10895575B2 (en) 2008-11-04 2021-01-19 Menarini Silicon Biosystems S.P.A. Method for identification, selection and analysis of tumour cells
JP2010151777A (ja) * 2008-11-19 2010-07-08 Sony Corp 微小粒子解析装置、微小粒子解析用マイクロチップ及び微小粒子解析方法
WO2010123594A2 (en) 2009-01-15 2010-10-28 Children's Medical Center Corporation Device for filtration of fluids there through and accompanying method
US8162149B1 (en) 2009-01-21 2012-04-24 Sandia Corporation Particle sorter comprising a fluid displacer in a closed-loop fluid circuit
DE102009005925B4 (de) 2009-01-23 2013-04-04 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Vorrichtung und Verfahren zur Handhabung von Biomolekülen
US20100298453A1 (en) * 2009-01-26 2010-11-25 Invista North America S.A R.L. Board stock foam having biobased content
JP5382852B2 (ja) 2009-02-06 2014-01-08 株式会社オンチップ・バイオテクノロジーズ 使い捨てチップ型フローセルとそれを用いたフローサイトメーター
US8828715B2 (en) * 2009-03-06 2014-09-09 Cfd Research Corporation Particle adhesion assay for microfluidic bifurcations
ITBO20090154A1 (it) * 2009-03-17 2010-09-18 Silicon Biosystems Spa Sistema microfluidico
NO2408562T3 (enExample) * 2009-03-17 2018-08-04
EP3415235B1 (en) 2009-03-23 2025-11-12 Bio-Rad Laboratories, Inc. Manipulation of microfluidic droplets
JP5333752B2 (ja) * 2009-03-27 2013-11-06 セイコーエプソン株式会社 細胞分離装置および細胞分離方法
US8343440B2 (en) 2009-03-27 2013-01-01 Seiko Epson Corporation Cell separating apparatus and cell separating method
JP4893794B2 (ja) * 2009-09-14 2012-03-07 セイコーエプソン株式会社 細胞分離装置
JP5248394B2 (ja) * 2009-03-30 2013-07-31 シャープ株式会社 被検体物質の固定化方法およびマイクロ分析装置
NL2002736C2 (en) 2009-04-09 2010-10-12 Univ Delft Tech Method for separating magnetic pieces of material.
WO2010117458A1 (en) 2009-04-10 2010-10-14 President And Fellows Of Harvard College Manipulation of particles in channels
US10031061B2 (en) 2009-05-13 2018-07-24 Intellicyt Corporation Flow measurement and control for improved quantification of particles in flow cytometry
US8790916B2 (en) * 2009-05-14 2014-07-29 Genestream, Inc. Microfluidic method and system for isolating particles from biological fluid
JP2011013208A (ja) * 2009-06-05 2011-01-20 Advance Co Ltd 生物学的操作システム及び工業的操作システム
SMT201700421T1 (it) 2009-06-10 2017-11-15 Cynvenio Biosystems Inc Dispositivi e metodi a flusso di guaina
CN102483424B (zh) 2009-06-26 2014-11-05 哈佛学院院长等 用于流体操作的方法以及微流体装置
DE102009030688A1 (de) 2009-06-26 2010-12-30 Carl Zeiss Ag Mikroskopische Detektion von Objekten in einem Fluidstrom
US8083069B2 (en) * 2009-07-31 2011-12-27 General Electric Company High throughput magnetic isolation technique and device for biological materials
US8202486B2 (en) * 2009-08-12 2012-06-19 Caliper Life Sciences, Inc. Pinching channels for fractionation of fragmented samples
US8834807B2 (en) 2009-08-12 2014-09-16 Caliper Life Sciences, Inc. Device and method for improving sample injection and stacking
US8697435B2 (en) 2009-08-31 2014-04-15 Mbio Diagnostics, Inc. Integrated sample preparation and analyte detection
WO2011028764A2 (en) 2009-09-02 2011-03-10 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
US9625454B2 (en) * 2009-09-04 2017-04-18 The Research Foundation For The State University Of New York Rapid and continuous analyte processing in droplet microfluidic devices
US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
US20110117577A1 (en) * 2009-10-20 2011-05-19 Agency For Science, Technology And Research Microfluidic system for trapping and detection of a biological entity in a sample
EP2517025B1 (en) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Methods for reducing the exchange of molecules between droplets
EP3671180B1 (en) 2010-01-15 2023-03-08 On-chip Biotechnologies Co., Ltd. Method of using an apparatus configured to separate biological particles
JP5846609B2 (ja) 2010-01-21 2016-01-20 バイオセップ リミテッド 希少細胞の磁気分離
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
WO2011100604A2 (en) 2010-02-12 2011-08-18 Raindance Technologies, Inc. Digital analyte analysis
US9110025B2 (en) * 2010-03-01 2015-08-18 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
US8236574B2 (en) * 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
US9678068B2 (en) 2010-03-01 2017-06-13 Quanterix Corporation Ultra-sensitive detection of molecules using dual detection methods
US8415171B2 (en) 2010-03-01 2013-04-09 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
CN103025431B (zh) 2010-04-07 2015-03-25 比奥森西亚专利有限公司 用于化验的流动控制装置
ITTO20100068U1 (it) * 2010-04-20 2011-10-21 Eltek Spa Dispositivi microfluidici e/o attrezzature per dispositivi microfluidici
JP2011237201A (ja) * 2010-05-06 2011-11-24 Sony Corp 微小粒子分取装置、マイクロチップ及びマイクロチップモジュール
JP5268989B2 (ja) * 2010-05-11 2013-08-21 株式会社日立ハイテクノロジーズ 核酸分析反応セルおよび核酸分析装置
GB2482658A (en) 2010-07-08 2012-02-15 Univ Dublin Non-linear magnetophoresis system
ITBO20100503A1 (it) * 2010-08-04 2012-02-05 Silicon Biosystems Spa Sistema microfluidico
ITBO20100505A1 (it) * 2010-08-04 2012-02-05 Silicon Biosystems Spa Sistema microfluidico
WO2012016357A1 (en) 2010-08-06 2012-02-09 Capitalbio Corporation Microarray-based assay integrated with particles for analyzing molecular interactions
US8468680B2 (en) 2010-08-24 2013-06-25 Roche Diagnostics Operations, Inc. Biosensor test member and method for making the same
KR20120026959A (ko) * 2010-09-10 2012-03-20 인제대학교 산학협력단 자기 영동을 이용한 미세 입자 분리 장치 및 이를 이용하여 미세 입자를 분리하는 방법
WO2012045012A2 (en) 2010-09-30 2012-04-05 Raindance Technologies, Inc. Sandwich assays in droplets
DE102010042737A1 (de) * 2010-10-21 2012-04-26 Siemens Aktiengesellschaft Magnetische Durchflusszytometrie
US9090865B2 (en) 2010-10-29 2015-07-28 The Regents Of The University Of California Systems and methods for particle classification and sorting
JP5732816B2 (ja) * 2010-10-29 2015-06-10 ソニー株式会社 細胞分取装置及び細胞分取チップ
JP2012095550A (ja) * 2010-10-29 2012-05-24 Sony Corp 細胞分取装置、細胞分取チップ及び細胞分取方法
CN102019277B (zh) * 2010-10-29 2013-05-22 北京惟馨雨生物科技有限公司 一种用于细胞和颗粒分离的分选仪及分选方法
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
WO2012067985A2 (en) 2010-11-18 2012-05-24 The Regents Of The University Of California Method and device for high-throughput solution exchange for cell and particle suspensions
US9815060B2 (en) 2010-11-18 2017-11-14 The Regents Of The University Of California Method and device for high-throughput solution exchange for cell and particle suspensions
EP3578522A1 (en) 2010-12-06 2019-12-11 Pall Corporation Continuous processing methods for biological products
IT1403518B1 (it) 2010-12-22 2013-10-31 Silicon Biosystems Spa Dispositivo microfluidico per la manipolazione di particelle
US8371683B2 (en) 2010-12-23 2013-02-12 Palo Alto Research Center Incorporated Particle removal device for ink jet printer
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
US20120214224A1 (en) * 2011-02-01 2012-08-23 Chan Eugene Y Flow based clinical analysis
EP3859011A1 (en) 2011-02-11 2021-08-04 Bio-Rad Laboratories, Inc. Methods for forming mixed droplets
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
US20130000738A1 (en) * 2011-02-28 2013-01-03 Pathogenetix, Inc. Method and system for transferring and/or concentrating a sample
DE102011015321A1 (de) 2011-03-28 2012-10-04 Ralph Heindrichs Verfahren zur kontinuierlichen selektiven Separation von Partikeln mittels Magnetismus
RU2013148071A (ru) * 2011-04-01 2015-05-10 Президент Энд Феллоуз Ов Харвард Колледж Аналогичное диализу терапевтическое (dlt) устройство
WO2012138882A2 (en) 2011-04-05 2012-10-11 Purdue Research Foundation Micro-fluidic system using micro-apertures for high throughput detection of cells
WO2012142301A2 (en) 2011-04-12 2012-10-18 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury
BR112013024148B1 (pt) 2011-04-27 2022-01-25 Becton, Dickinson And Company Dispositivo, método e sistema para separar partes marcadas magneticamente em uma amostra, método de separar partes marcadas magneticamente em uma amostra
CN103492081B (zh) * 2011-04-29 2017-05-31 贝克顿·迪金森公司 流体管线式粒子固定和收集系统以及其使用方法
DE102011076051A1 (de) * 2011-05-18 2012-11-22 Siemens Aktiengesellschaft Magnetophoretische Analytselektion und -anreicherung
US9238206B2 (en) 2011-05-23 2016-01-19 President And Fellows Of Harvard College Control of emulsions, including multiple emulsions
DE202012013668U1 (de) 2011-06-02 2019-04-18 Raindance Technologies, Inc. Enzymquantifizierung
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
EP3120923A3 (en) 2011-07-06 2017-03-01 President and Fellows of Harvard College Article comprising a particle having a shell and a fluid
US10240186B2 (en) 2011-07-14 2019-03-26 Fluxion Biosciences, Inc. Devices, systems, and methods for magnetic separation
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
GB201113007D0 (en) * 2011-07-28 2011-09-14 Q Chip Ltd Bead collection device and method
US20130029355A1 (en) * 2011-07-28 2013-01-31 Electronics And Telecommunications Research Institute Multiple analysis device and method for analyzing cancer cells in blood
US20130075318A1 (en) * 2011-09-23 2013-03-28 Xiaojing Zhang Apparatus for Isolating Rare Cells from Blood Samples
ITTO20110990A1 (it) 2011-10-28 2013-04-29 Silicon Biosystems Spa Metodo ed apparato per l'analisi ottica di particelle a basse temperature
ITBO20110766A1 (it) 2011-12-28 2013-06-29 Silicon Biosystems Spa Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico
EP2644259A1 (en) 2012-03-29 2013-10-02 Roche Diagniostics GmbH Micro flow filtration system and flow filtration method
EP2644258A1 (en) * 2012-03-29 2013-10-02 Roche Diagniostics GmbH Micro flow filtration system and flow filtration method for a fluid sample
US9556412B2 (en) * 2012-04-17 2017-01-31 Regents Of The University Of Minnesota Inlet and outlet geometries for a vertical three-stream microfluidic device
US8685708B2 (en) 2012-04-18 2014-04-01 Pathogenetix, Inc. Device for preparing a sample
US9028776B2 (en) 2012-04-18 2015-05-12 Toxic Report Llc Device for stretching a polymer in a fluid sample
US9517474B2 (en) * 2012-05-18 2016-12-13 University Of Georgia Research Foundation, Inc. Devices and methods for separating particles
US9840732B2 (en) 2012-05-21 2017-12-12 Fluidigm Corporation Single-particle analysis of particle populations
DE102012211626A1 (de) * 2012-07-04 2014-01-09 Siemens Aktiengesellschaft Anordnung zur Quantifizierung von Zellen einer Zellsuspension
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
JP5910412B2 (ja) * 2012-08-16 2016-04-27 ソニー株式会社 微小粒子分取方法及び微小粒子分取用マイクロチップ
EP2912189B8 (en) 2012-10-26 2024-07-17 Becton, Dickinson and Company Devices and methods for manipulating components in a fluid sample
US20140151229A1 (en) * 2012-12-05 2014-06-05 Caliper Life Sciences, Inc. Manipulation of objects in microfluidic devices using external electrodes
US20140168328A1 (en) * 2012-12-18 2014-06-19 Palo Alto Research Center Incorporated Non-spherical particle separator for ink jet printer
KR101356933B1 (ko) * 2012-12-28 2014-01-29 고려대학교 산학협력단 표면탄성파를 이용한 미세유동 크로마토 그래피 기반 미세입자 분리 장치 및 방법
WO2014113502A1 (en) 2013-01-15 2014-07-24 Quanterix Corporation Detection of dna or rna using single molecule arrays and other techniques
FR3001038B1 (fr) * 2013-01-17 2018-02-09 Centre National De La Recherche Scientifique (Cnrs) Procede de capture, procede de detection et kit de capture d'une molecule dans un echantillon
US9322013B2 (en) * 2013-02-25 2016-04-26 Los Alamos National Security, Llc Magnetic separation of algae
US10662408B2 (en) 2013-03-14 2020-05-26 Inguran, Llc Methods for high throughput sperm sorting
US9757726B2 (en) 2013-03-14 2017-09-12 Inguran, Llc System for high throughput sperm sorting
US10371622B2 (en) 2013-03-14 2019-08-06 Inguran, Llc Device for high throughput sperm sorting
WO2014145765A1 (en) 2013-03-15 2014-09-18 Ancera, Inc. Systems and methods for bead-based assays in ferrofluids
US20160296945A1 (en) 2013-03-15 2016-10-13 Ancera, Inc. Systems and methods for active particle separation
CN103305603B (zh) * 2013-03-26 2015-05-20 上海交通大学 单分子生物反应器制备单微纳米珠携带单根多聚物的方法
CN103217311B (zh) * 2013-03-26 2015-04-01 上海交通大学 生物复合物的分离与收集方法
CN103194371B (zh) * 2013-03-26 2014-12-24 上海交通大学 生物复合物的分离与收集装置
CN103194370B (zh) * 2013-03-26 2014-12-24 上海交通大学 制备与富集单个微纳米珠携带单根多聚物分子的装置
CN103196725B (zh) * 2013-03-26 2015-07-08 上海交通大学 制备与富集单个微纳米珠携带单根多聚物分子的方法
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
JP5780274B2 (ja) * 2013-07-31 2015-09-16 セイコーエプソン株式会社 細胞回収方法
WO2015038978A1 (en) 2013-09-13 2015-03-19 Symbolics, Llc Lateral flow assays using two dimensional test and control signal readout patterns
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
WO2015052034A1 (en) * 2013-10-07 2015-04-16 Devrim Pesen Okvur Microfluidic device for investigation of distance dependent interactions in cell biology
US10202577B2 (en) * 2013-10-18 2019-02-12 The General Hospital Corporation Microfluidic sorting using high gradient magnetic fields
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
GB201320146D0 (en) * 2013-11-14 2014-01-01 Cambridge Entpr Ltd Fluidic separation and detection
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
EP3108219B1 (en) * 2014-02-20 2020-04-01 Malvern Panalytical Limited Heterogeneous fluid sample characterization
DE102014203285A1 (de) * 2014-02-24 2015-08-27 Miltenyi Biotec Gmbh Hydrodynamische Fokussierungseinheit
US20170074870A1 (en) 2014-03-14 2017-03-16 Northeastern University Microfluidic System and Method for Real-Time Measurement of Antibody-Antigen Binding and Analyte Detection
US8820538B1 (en) * 2014-03-17 2014-09-02 Namocell LLC Method and apparatus for particle sorting
DE102014205949A1 (de) * 2014-03-31 2015-10-01 Siemens Aktiengesellschaft Durchflusskammer für einen Durchflusszytometer sowie Durchflusszytometer
GB2528632A (en) * 2014-04-30 2016-02-03 Cambridge Entpr Ltd Fluidic analysis and separation
US10031104B2 (en) * 2014-06-13 2018-07-24 Yes Way Intellectual Holdings, Llc Mobile micro-lab for chemical analysis of fluids
CA2958118C (en) * 2014-08-20 2019-05-21 Stem Sel S.R.L. Device for the fractionation of objects and fractionation method
DE102014112270B3 (de) 2014-08-27 2015-04-23 Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V. Verfahren zur Messung der Thrombozytenfunktion
JP6104475B2 (ja) * 2014-08-28 2017-04-05 シスメックス株式会社 粒子撮像装置および粒子撮像方法
DE102014116567A1 (de) * 2014-11-12 2016-05-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zum Sortieren von Mikropartikeln in einem Fluidstrom
JP2018509615A (ja) 2015-02-19 2018-04-05 プレミアム ジェネティクス (ユーケー) リミテッド 走査型赤外線測定システム
US10167502B2 (en) 2015-04-03 2019-01-01 Fluxion Biosciences, Inc. Molecular characterization of single cells and cell populations for non-invasive diagnostics
EP3998335A3 (en) 2015-05-08 2022-07-27 Biomagnetic Solutions LLC Apparatus and method for immunomagnetic cell separation
JP6962563B2 (ja) 2015-05-12 2021-11-05 株式会社オンチップ・バイオテクノロジーズ 単一粒子解析方法およびその解析のためのシステム
WO2016210348A2 (en) 2015-06-26 2016-12-29 Ancera, Inc. Background defocusing and clearing in ferrofluid-based capture assays
ES2599056B2 (es) * 2015-07-31 2017-07-07 Pablo ALBERTOS SÁNCHEZ Dispositivo para ensayar una muestra de células
US10676719B2 (en) 2015-07-31 2020-06-09 University Of Georgia Research Foundation, Inc. Devices and methods for separating particles
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
DE102015218177B4 (de) 2015-09-22 2022-09-01 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Isolation und Anreicherung magnetisch markierter Zellen im Durchfluss
CA3000010C (en) 2015-10-02 2025-05-06 The Board Of Trustees Of The Leland Stanford Junior University Sorting of biological and non-biological fragments using magnetic levitation
CN108430634B (zh) * 2015-11-30 2021-04-20 快速定量微生物学股份有限公司 微流体装置、组件和从样品提取颗粒的方法
CN105536664B (zh) * 2015-12-12 2017-06-20 西安交通大学 一种用于可控筛选流体中粒子的微反应器的制备方法
KR101855490B1 (ko) * 2016-01-22 2018-05-08 한국과학기술원 점탄성유체와 점성유체의 병행층류를 이용한 미소 입자 분리 및 세정 방법
US10962527B2 (en) * 2016-02-05 2021-03-30 The Broad Institute, Inc. Multi-stage, multiplexed target isolation and processing from heterogeneous populations
US20170259262A1 (en) * 2016-03-09 2017-09-14 Intelligent Bio-Systems, Inc. Laminar fluidic separation in flowcells for minimal reagent usage
CA3019814A1 (en) 2016-04-04 2017-10-12 CyteQuest, Inc. System, device and method for electroporation of cells
WO2017181258A1 (en) * 2016-04-21 2017-10-26 Duane Hewitt Continuous flow system
US9968943B2 (en) * 2016-06-30 2018-05-15 United Arab Emirates University Magnetic particle separator
US10189029B2 (en) * 2016-06-30 2019-01-29 United Arab Emirates University Magnetic particle separator
CN116429665A (zh) 2016-09-16 2023-07-14 芯片生物技术株式会社 微粒分注装置、微粒分析装置、反应检测装置、以及使用它们的方法
WO2018184002A1 (en) * 2017-04-01 2018-10-04 Biomagnetic Solutions Llc Devices and methods for one-step static or continuous magnetic separation
GB201706947D0 (en) 2017-05-02 2017-06-14 Cytosight Ltd Fluid sample enrichment system
US10350611B2 (en) * 2017-06-27 2019-07-16 General Electric Company Apparatus and methods for particle separation by ferrofluid constriction
US11364503B2 (en) * 2017-07-17 2022-06-21 Hewlett-Packard Development Company, L.P. Dielectrophoresis separators with cell ejection devices
CN107340226A (zh) * 2017-08-03 2017-11-10 江苏大学 一种油液中悬浮微粒计数检测装置及其应用
CA3071593A1 (en) * 2017-08-04 2019-02-07 University Of Georgia Research Foundation, Inc. Devices and methods for separating circulating tumor cells from biological samples
US11292000B2 (en) 2017-08-04 2022-04-05 University Of Georgia Research Foundation, Inc. Devices and methods for separating circulating tumor cells from biological samples
US11648559B2 (en) 2017-08-04 2023-05-16 University Of Georgia Research Foundation, Inc. Devices and methods for separating circulating tumor cells from biological samples
WO2019031815A1 (ko) * 2017-08-07 2019-02-14 울산과학기술원 자성 입자를 이용한 유체 분리 시스템 및 방법
KR102260437B1 (ko) * 2017-12-28 2021-06-02 인하대학교 산학협력단 결정성 나노셀룰로오스의 길이별 분리장치
KR102327920B1 (ko) * 2017-12-28 2021-11-17 인하대학교 산학협력단 결정성 나노셀룰로오스의 길이별 분리장치
DE102018104669A1 (de) * 2018-03-01 2019-09-05 Dionex Softron Gmbh Verwendung einer akustischen Welle in einem Chromatographiesystem
CN111771116B (zh) * 2018-03-02 2024-03-05 索尼公司 用于优化微粒吸入条件的方法、微粒分选装置和系统
WO2019209868A1 (en) * 2018-04-23 2019-10-31 Chris Yu New apparatus and methods for disease detection
US11181132B2 (en) * 2018-04-30 2021-11-23 Vivonics, Inc. Apparatus and method for controlling fluid flow
US11413378B2 (en) 2018-05-08 2022-08-16 Biomagnetic Solutions Llc Rigid chamber for cell separation from a flexible disposable bag
BR112020023607A2 (pt) 2018-05-23 2021-02-17 Abs Global, Inc. sistemas e métodos para focalização de partículas em microcanais
US12180440B2 (en) * 2018-06-01 2024-12-31 Sony Corporation Microchip and sample sorting kit
CN108680403B (zh) * 2018-06-21 2024-03-29 重庆交通大学 附加压流式多级亚微米粒子采集器
WO2020011193A1 (en) * 2018-07-11 2020-01-16 The University Of Hong Kong Automatic microfluidic system for continuous and quantitive collection of droplets
WO2020028639A1 (en) 2018-08-01 2020-02-06 Essen Instruments, Inc. D/B/A Essen Bioscience, Inc. Methods, kits and stain compositions for flow cytometry evaluation of unassociated virus-size particles using multiple fluorogenic dyes
CN109174445B (zh) * 2018-08-23 2020-03-31 山东路友再生资源设备有限公司 一种飞秒激光涡流磁选机
EP3857215A4 (en) * 2018-09-24 2022-06-22 Hewlett-Packard Development Company, L.P. PARTICLE SEPARATION FROM WHOLE BLOOD
WO2020072303A1 (en) * 2018-10-03 2020-04-09 Verily Life Sciences Llc Systems and methods for maintaining constant volumetric flow rates in a fluid channel
US11137337B2 (en) 2019-01-21 2021-10-05 Essen Instruments, Inc. Flow cytometry with data analysis for optimized dilution of fluid samples for flow cytometry investigation
CN109856398B (zh) * 2019-01-31 2022-04-29 京东方科技集团股份有限公司 疫苗检测装置及其检测方法
KR102279854B1 (ko) * 2019-02-13 2021-07-21 인제대학교 산학협력단 자기영동을 이용한 음성수집 방식의 미세입자 분리장치 및 그 분리방법
EP3501658B1 (en) 2019-03-19 2021-04-21 Ace Medical Technology Co., Ltd. Device for sorting bio-particles using a force generated from light-induced dielectrophoresis and operating method thereof
EP3948279B1 (en) 2019-03-26 2025-06-18 Sartorius BioAnalytical Instruments, Inc. Flow cytometry evaluation for unassociated non-enveloped viral particles
CN117413819A (zh) 2019-04-18 2024-01-19 艾步思国际有限责任公司 用于连续添加冷冻保护剂的系统和工艺
GB2587459B (en) * 2019-06-05 2024-03-13 Jaguar Land Rover Ltd Device for manipulating a substance
CN110438000B (zh) * 2019-07-24 2021-10-12 中山大学 双频驻波声场分离循环肿瘤细胞及其微栓的装置与方法
US11123734B2 (en) 2019-07-31 2021-09-21 CytoVale Inc. System and method for immune activity determination
CA3097579A1 (en) 2019-10-28 2021-04-28 Op-Hygiene Ip Gmbh Method of identifying biologic particles
US11628439B2 (en) 2020-01-13 2023-04-18 Abs Global, Inc. Single-sheath microfluidic chip
US11709116B2 (en) 2020-02-04 2023-07-25 Sartorius Bioanalytical Instruments, Inc. Liquid flourescent dye concentrate for flow cytometry evaluation of virus-size particles and related products and methods
IT202000006031A1 (it) * 2020-03-20 2021-09-20 Celldynamics I S R L Dispositivo fluidico per analisi di corpuscoli e relativo metodo
US20220088604A1 (en) * 2020-09-24 2022-03-24 Micareo Taiwan Co., Ltd. Microfluidic chip and device
EP3978119A1 (en) 2020-09-30 2022-04-06 Levitas, Inc. Particle separator system, materials, and methods of use
CN116368237A (zh) 2020-10-21 2023-06-30 Abs全球股份有限公司 用于处理遗传样本以确定特性或检测污染的方法及系统
US11951476B2 (en) * 2020-11-19 2024-04-09 Rutgers, The State University Of New Jersey Electronic-sensing and magnetic-modulation (ESMM) biosensor for phagocytosis quantification in pathogenic infections and methods of use thereof
WO2022108840A1 (en) 2020-11-23 2022-05-27 Abs Global, Inc. Modular flow cytometry systems and methods of processing samples
CN112871750B (zh) * 2021-01-26 2022-12-02 华南师范大学 基于级联式微型热源的颗粒分选芯片及其颗粒分选方法
US20230131266A1 (en) * 2021-10-21 2023-04-27 Hewlett-Packard Development Company, L.P. Alignment and fusion of cells with an electrical field
WO2023153331A1 (ja) * 2022-02-08 2023-08-17 京セラ株式会社 流路デバイスの準備方法
US12030053B1 (en) 2023-05-05 2024-07-09 Panazee Inc. Multi-step kinetic immunoassay systems and methods
US11802870B1 (en) * 2022-12-13 2023-10-31 Panazee Kinetic immunoassay systems and methods
CN116493057B (zh) * 2023-02-16 2025-07-18 河海大学常州校区 一种精准分离微纳米颗粒的微流控装置及其操控方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1894146A (en) * 1931-04-30 1933-01-10 John S Baker Score card holder or writing tablet
US3560754A (en) 1965-11-17 1971-02-02 Ibm Photoelectric particle separator using time delay
US3827555A (en) 1973-03-05 1974-08-06 Bio Physics Systems Inc Particle sorter with segregation indicator
US4279345A (en) * 1979-08-03 1981-07-21 Allred John C High speed particle sorter using a field emission electrode
ATE48477T1 (de) 1984-09-11 1989-12-15 Partec Ag Verfahren und vorrichtung zur sortierung von mikroskopischen partikeln.
EP0196205A2 (en) 1985-03-27 1986-10-01 The Standard Oil Company Improved apparatus for segregating particulate matter
DE3522365A1 (de) 1985-06-22 1987-01-02 Bayer Ag Trenngeraet fuer magnetische partikel aus fluessiger phase
US4894146A (en) 1986-01-27 1990-01-16 University Of Utah Thin channel split flow process and apparatus for particle fractionation
NO162946C (no) * 1987-08-21 1990-03-14 Otto Soerensen Anordning for magnetisk separasjon av celler.
US5053344A (en) * 1987-08-04 1991-10-01 Cleveland Clinic Foundation Magnetic field separation and analysis system
US5123901A (en) 1988-02-25 1992-06-23 Carew E Bayne Method for separating pathogenic or toxic agents from a body fluid and return to body
US5039426A (en) 1988-05-17 1991-08-13 University Of Utah Process for continuous particle and polymer separation in split-flow thin cells using flow-dependent lift forces
DE3827252A1 (de) 1988-08-11 1990-02-15 Unkelbach Karl Heinz Dr Verfahren und vorrichtung zum kontinuierlichen trennen von biologische mikrosysteme und zellen enthaltenden mischungen
US5092973A (en) 1990-01-26 1992-03-03 The Board Of Trustees Of The Leland Stanford Junior University Rectangular capillaries for capillary electrophoresis
GB9008044D0 (en) 1990-04-09 1990-06-06 Hatfield Polytechnic Higher Ed Microfabricated device for biological cell sorting
US5460797A (en) * 1991-05-08 1995-10-24 Streck Laboratories, Inc. Method for fixing tissues and cells for analysis using oxazolidine compounds
US5304487A (en) * 1992-05-01 1994-04-19 Trustees Of The University Of Pennsylvania Fluid handling in mesoscale analytical devices
DE69303898T3 (de) * 1992-05-01 2007-01-18 Trustees Of The University Of Pennsylvania Fluessigkeitsbehandlung in mikrofabrizierten analytischen vorrichtungen
TW239881B (enExample) 1992-12-22 1995-02-01 Sienna Biotech Inc
JPH08506664A (ja) * 1993-02-01 1996-07-16 セック,リミテッド Dna配列決定の方法および装置
US5483469A (en) 1993-08-02 1996-01-09 The Regents Of The University Of California Multiple sort flow cytometer
JPH07232097A (ja) 1994-02-24 1995-09-05 Power Reactor & Nuclear Fuel Dev Corp 磁気クロマトグラフィー法による群分離方法
EP0778899A4 (en) 1994-09-20 2001-08-29 Miltenyi Biotech Inc ENRICHMENT OF FETAL CELLS FROM MATERNAL BLOOD
US5528045A (en) 1995-04-06 1996-06-18 Becton Dickinson And Company Particle analyzer with spatially split wavelength filter

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