HK1094008A1 - Casein hydrolyzate, process for producing the same and use thereof - Google Patents

Casein hydrolyzate, process for producing the same and use thereof

Info

Publication number
HK1094008A1
HK1094008A1 HK07100122.4A HK07100122A HK1094008A1 HK 1094008 A1 HK1094008 A1 HK 1094008A1 HK 07100122 A HK07100122 A HK 07100122A HK 1094008 A1 HK1094008 A1 HK 1094008A1
Authority
HK
Hong Kong
Prior art keywords
pro
vivo
peptides
casein
amino acids
Prior art date
Application number
HK07100122.4A
Other languages
English (en)
Inventor
Naoyuki Yamamoto
Seiichi Mizuno
Shingo Nishimura
Takanobu Gotou
Keiichi Matsuura
Tadashi Shinoda
Original Assignee
Calpis Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calpis Co Ltd filed Critical Calpis Co Ltd
Publication of HK1094008A1 publication Critical patent/HK1094008A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • C07K5/06095Arg-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK07100122.4A 2003-08-01 2007-01-04 Casein hydrolyzate, process for producing the same and use thereof HK1094008A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003285007 2003-08-01
PCT/JP2004/010928 WO2005012542A1 (ja) 2003-08-01 2004-07-30 カゼイン加水分解物、その製造法及びその用途

Publications (1)

Publication Number Publication Date
HK1094008A1 true HK1094008A1 (en) 2007-03-16

Family

ID=34113859

Family Applications (2)

Application Number Title Priority Date Filing Date
HK07100122.4A HK1094008A1 (en) 2003-08-01 2007-01-04 Casein hydrolyzate, process for producing the same and use thereof
HK07100123.3A HK1093991A1 (en) 2003-08-01 2007-01-04 Biologically non-degradable peptide, angiotensin converting enzyme inhibitor, drug and functional food

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK07100123.3A HK1093991A1 (en) 2003-08-01 2007-01-04 Biologically non-degradable peptide, angiotensin converting enzyme inhibitor, drug and functional food

Country Status (23)

Country Link
US (3) US20070122451A1 (pt)
EP (2) EP1669463B1 (pt)
JP (3) JP5341300B2 (pt)
KR (3) KR101115560B1 (pt)
CN (3) CN100439393C (pt)
AT (2) ATE442855T1 (pt)
AU (2) AU2004261522B2 (pt)
BR (2) BRPI0413242A (pt)
CA (2) CA2532537A1 (pt)
DE (2) DE602004017202D1 (pt)
DK (2) DK1669463T3 (pt)
EA (2) EA011570B1 (pt)
ES (2) ES2331312T3 (pt)
HK (2) HK1094008A1 (pt)
MX (2) MXPA06000878A (pt)
NO (2) NO20060994L (pt)
NZ (2) NZ545340A (pt)
PL (1) PL1669463T3 (pt)
PT (2) PT1661909E (pt)
TW (2) TWI349676B (pt)
UA (2) UA87278C2 (pt)
WO (2) WO2005012542A1 (pt)
ZA (2) ZA200601739B (pt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2599859T3 (es) * 2005-02-24 2017-02-03 Dsm Ip Assets B.V. Proceso enzimático para producir I-P-P a partir de caseína kappa
WO2006114193A1 (en) * 2005-04-28 2006-11-02 Unilever N.V. Peptides having an ace inhibiting effect
EP1874128A1 (en) * 2005-04-28 2008-01-09 Hindustan Unilever Limited Peptides having an ace inhibiting effect
DE602006020028D1 (de) * 2005-04-28 2011-03-24 Unilever Nv Gesundheitsfördernde peptide und sie enthaltende zusammensetzungen
WO2007013426A1 (ja) 2005-07-26 2007-02-01 Calpis Co., Ltd. 発酵乳の製造方法及び発酵乳飲食品
US7989418B2 (en) * 2005-10-28 2011-08-02 Nestec S.A. Methods for the use of branched chain amino acids
EP1992354B1 (en) * 2006-02-09 2014-04-09 Calpis Co., Ltd. Rheumatoid arthritis-preventive agent for oral intake
JP4956164B2 (ja) * 2006-12-06 2012-06-20 味の素株式会社 メラニン輸送及び/又は放出抑制剤
EA016808B1 (ru) * 2007-03-27 2012-07-30 Калпис Ко., Лтд. ПРИМЕНЕНИЕ ТРИПЕПТИДОВ Val Pro Pro И Ile Pro Pro ДЛЯ СУПРЕССИИ УТОЛЩЕНИЯ СТЕНКИ СЕРДЦА
CN101095457B (zh) * 2007-06-23 2010-04-07 临夏州华安生物制品有限责任公司 酸水解酪蛋白的生产方法
JP5750039B2 (ja) * 2008-03-26 2015-07-15 グランビア ニュートリショナルズ (アイルランド) リミテッド ロイシンリッチペプチド組成物および単離法
CN101768209B (zh) * 2009-01-05 2011-08-31 北京林业大学 具有高体内活性的降血压肽及其制备和纯化方法
CN101570568B (zh) * 2009-06-15 2012-05-30 东北农业大学 一种发酵乳中的ace抑制肽及其制备方法
CN102187935B (zh) * 2010-03-19 2012-12-19 江南大学 一种制备酪蛋白磷酸肽与ace抑制肽的方法
CN102399261B (zh) * 2010-09-07 2014-06-25 任发政 具有血管紧张素转化酶c-端选择性抑制活性的三肽及其应用和组合物
US20120115786A1 (en) * 2010-11-09 2012-05-10 Calpis Co., Ltd. Agent for reducing risk in onset of disease ascribable to non-dipper circadian rhythm of blood pressure
US9523109B2 (en) 2011-06-24 2016-12-20 Calpis Co., Ltd. Method for enzymatically preparing peptides for use in improvement of brain function
JP5718741B2 (ja) * 2011-06-24 2015-05-13 カルピス株式会社 脳機能改善用ペプチドの酵素的製造方法
EP2765862A2 (en) * 2011-10-14 2014-08-20 Abbott Laboratories Sterilized liquid protein supplement
CN103215332A (zh) * 2013-04-16 2013-07-24 陕西科技大学 一种分步酶解羊乳酪蛋白制备ace抑制肽的方法
JP6306197B2 (ja) 2013-10-04 2018-04-04 イノウェイ・カンパニー・リミテッド 動物性タンパク加水分解物、その製造方法及びその用途
FR3017536B1 (fr) * 2014-02-18 2017-05-26 Univ La Rochelle Compositions pour la prevention et/ou le traitement de pathologies liees a l'alpha-glucosidase
ES2544153B1 (es) * 2014-02-24 2016-06-06 Ntd Labs, S.L. Uso de un hidrolizado de caseína como agente antiviral
JP6251667B2 (ja) 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
CN105693817B (zh) 2014-11-27 2020-06-05 西北大学 一类三肽化合物及其制备方法与应用
JP6005202B2 (ja) * 2015-03-19 2016-10-12 アサヒグループホールディングス株式会社 脳機能改善用ペプチドの酵素的製造方法
JP6625366B2 (ja) * 2015-08-05 2019-12-25 学校法人北里研究所 豚肉の熟成中に生成する生理活性ペプチドを含む血圧降下剤及び食品、並びにペプチドを指標とする豚肉の熟成評価法
CN106119325A (zh) * 2016-06-23 2016-11-16 哈尔滨商业大学 一种具有增加肌肉含量和力量作用的酪蛋白水解物的制备方法
CN107375897A (zh) * 2017-08-15 2017-11-24 普维食品发展(上海)有限公司 一种辅助降血压的组合物及其用途
CN107348511B (zh) * 2017-08-21 2018-04-06 东方红(通化)生物医药股份有限公司 一种具有辅助降血压作用的西洋参/人参提取物的发酵提取方法
CN108003231A (zh) * 2017-11-13 2018-05-08 江苏大学 一种降低小分子肽中游离氨基酸含量的方法
CN108588156A (zh) * 2018-04-24 2018-09-28 浙江大学 一种水牛乳酪蛋白抗氧化活性肽的制备方法
JPWO2019208700A1 (ja) * 2018-04-26 2021-04-30 ゼリア新薬工業株式会社 ジペプチド及びこれを含有する医薬組成物
CN110467649A (zh) * 2019-09-12 2019-11-19 浙江省农业科学院 一种抑制血管紧张素转换酶活性的多肽qeip及其应用
CN113321719B (zh) * 2021-05-20 2022-03-18 澳优乳业(中国)有限公司 一种寡肽及其制备方法与应用
CN114656521B (zh) * 2022-04-01 2023-08-18 广西大学 抑制新型冠状病毒刺突蛋白与ace2结合的化合物及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6023087B2 (ja) * 1982-09-04 1985-06-05 工業技術院長 アンジオテンシン転換酵素阻害剤
FR2608051B1 (fr) * 1986-12-15 1989-04-07 Bellon Labor Sa Roger Procede de fabrication d'un hydrolysat enzymatique de proteines riche en di- et tri-peptides, utilisable notamment en nutrition artificielle et en dietetique
JPH0630615B2 (ja) * 1988-07-27 1994-04-27 江崎グリコ株式会社 低分子ペプチド組成物及びその製造方法
JPH0262828A (ja) 1988-08-26 1990-03-02 Ajinomoto Co Inc 新規ベプチドおよびこれを含有する降圧剤
JPH03120225A (ja) 1989-10-04 1991-05-22 Ajinomoto Co Inc 新規ペプチドおよびこれを含有する降圧剤
DE69127020T2 (de) * 1990-05-18 1998-01-29 Morinaga Milk Industry Co Ltd Milchproteinhydrolysate und Zusammensetzungen zur Verwendung als Haar- und Hautbehandlungsmittel
JP3010795B2 (ja) * 1991-07-04 2000-02-21 不二製油株式会社 ペプチドの苦味除去方法
JP3378279B2 (ja) 1991-11-07 2003-02-17 株式会社日清製粉グループ本社 ペプチドおよびその製造方法
JPH05252979A (ja) * 1992-02-28 1993-10-05 Nippon Steel Corp 低分子ペプチドの製造方法
JP2782142B2 (ja) 1992-07-23 1998-07-30 カルピス株式会社 アンジオテンシン変換酵素阻害剤及びその製造法
DK46793D0 (da) * 1993-04-26 1993-04-26 Novo Nordisk As Enzym
DK0981630T3 (da) * 1997-05-16 2009-03-09 Novozymes Inc Polypeptider med prolyldipeptidylaminopeptidaseaktivitet og nukleinsyrer, der koder for samme
JP2873327B2 (ja) * 1998-01-23 1999-03-24 工業技術院長 アンジオテンシン変換酵素阻害剤
JP4633876B2 (ja) * 1999-11-11 2011-02-16 カルピス株式会社 トリペプチドの製造方法
EP1163853B1 (en) * 1999-11-29 2007-02-21 Kyowa Hakko Food Specialties Co., Ltd. Method of strengthenig the taste of sodium chloride, agent for strengthening the taste of sodium chloride, sodium chloride-taste seasoning and food having strengthened taste of sodium chloride
JP4490547B2 (ja) * 2000-03-30 2010-06-30 株式会社 レオロジー機能食品研究所 新規ペプチド、その製造法及び用途
JP4436961B2 (ja) * 2000-07-25 2010-03-24 森永乳業株式会社 蛋白質加水分解物の製造方法
JP2003024012A (ja) * 2001-07-18 2003-01-28 National Institute Of Advanced Industrial & Technology アンジオテンシンi変換酵素阻害剤及び血圧降下性機能食品
AU2002366037B2 (en) * 2001-11-21 2005-11-03 Morinaga Milk Industry Co., Ltd. Novel peptide having angiotensin convertase inhibitory effect
JP2003210138A (ja) 2002-01-24 2003-07-29 Yoko Takenaka 機能性食品、その製造方法及び医薬
US7900438B2 (en) * 2006-07-28 2011-03-08 General Electric Company Heat transfer system and method for turbine engine using heat pipes

Also Published As

Publication number Publication date
NO20060995L (no) 2006-02-28
DK1661909T3 (da) 2010-01-18
KR101115560B1 (ko) 2012-03-13
ZA200601739B (en) 2007-05-30
KR20110039379A (ko) 2011-04-15
EA200600349A1 (ru) 2006-08-25
KR101174299B1 (ko) 2012-08-16
US20070299014A1 (en) 2007-12-27
ES2331312T3 (es) 2009-12-29
US20110082281A1 (en) 2011-04-07
CA2532537A1 (en) 2005-02-10
EP1669463B1 (en) 2008-10-15
UA89616C2 (ru) 2010-02-25
DE602004017202D1 (de) 2008-11-27
WO2005012334A1 (ja) 2005-02-10
CN100439393C (zh) 2008-12-03
EP1661909A4 (en) 2006-08-30
NZ545340A (en) 2010-04-30
EA010098B1 (ru) 2008-06-30
EP1661909B1 (en) 2009-09-16
AU2004261522B2 (en) 2010-09-16
CN100398661C (zh) 2008-07-02
BRPI0413242A (pt) 2006-10-03
EP1661909A1 (en) 2006-05-31
CA2546497A1 (en) 2005-02-10
ES2313067T3 (es) 2009-03-01
CN101381401A (zh) 2009-03-11
EP1669463A4 (en) 2006-08-23
ATE442855T1 (de) 2009-10-15
CN1833031A (zh) 2006-09-13
PL1669463T3 (pl) 2009-02-27
NZ545341A (en) 2009-06-26
NO20060994L (no) 2006-02-28
HK1093991A1 (en) 2007-03-16
EP1669463A1 (en) 2006-06-14
KR20060118395A (ko) 2006-11-23
JPWO2005012334A1 (ja) 2008-01-17
ZA200601746B (en) 2007-05-30
MXPA06000878A (es) 2006-03-30
AU2004261855A1 (en) 2005-02-10
CN1832958A (zh) 2006-09-13
TWI341866B (en) 2011-05-11
ATE411035T1 (de) 2008-10-15
DK1669463T3 (da) 2009-01-26
US8580557B2 (en) 2013-11-12
EA011570B1 (ru) 2009-04-28
JP2011102327A (ja) 2011-05-26
KR101115557B1 (ko) 2012-03-13
TW200505471A (en) 2005-02-16
PT1661909E (pt) 2009-12-17
AU2004261855B2 (en) 2010-09-16
UA87278C2 (ru) 2009-07-10
TWI349676B (en) 2011-10-01
WO2005012542A1 (ja) 2005-02-10
EA200600352A1 (ru) 2006-08-25
JPWO2005012542A1 (ja) 2007-09-27
AU2004261522A1 (en) 2005-02-10
US20070122451A1 (en) 2007-05-31
WO2005012334A8 (ja) 2005-06-30
DE602004023210D1 (de) 2009-10-29
JP4669396B2 (ja) 2011-04-13
KR20060120567A (ko) 2006-11-27
JP5341300B2 (ja) 2013-11-13
TW200507869A (en) 2005-03-01
BRPI0413238A (pt) 2006-10-03
MXPA06000879A (es) 2006-03-30
PT1669463E (pt) 2009-01-23

Similar Documents

Publication Publication Date Title
HK1094008A1 (en) Casein hydrolyzate, process for producing the same and use thereof
WO2003037932A3 (en) Human coagulation factor vii polypeptides
MXPA01007956A (es) Polipeptido antimicrobiano/neutralizador de endotoxina.
ITRM20010380A1 (it) Composizione comprendente gelatina di pesce parzialmente idrolizzata e loro uso.
JP6864539B2 (ja) コラーゲン、ゼラチンおよびコラーゲン加水分解物に含まれるGly−X−Y配列量の測定方法、およびX−Y配列量の測定方法
DE602005024809D1 (de) Verfahren zur herstellung von gabapentin
MY141221A (en) Casein hydrolyzate, process for producing the same, and use thereof
EE200000478A (et) Peptiid, seda kodeeriv geen, diagnostiline reagent ja diagnostiline reaktiivikomplekt ning vaktsiinkasutamiseks riketsioosi ravis
WO2005116658A3 (en) Method for determining a tissue degradation process by detection of comp neoepitopes
EP1651765B8 (en) Novel photobacterium damselae nucleotide and amino acid sequences and uses thereof
WO2004085469A3 (en) Secreted protein family
ATE281522T1 (de) Sentrin-spezifische menschliche protease senp1
WO2004046199A3 (fr) Procede d'obtention d'acide chondroitine sulfurique et ses utilisations
EP1467207A4 (en) SCREENING PROCESS
WO2003083472A1 (fr) Methode d'evaluation du risque de maladie parodontale
MX2021014268A (es) Proteina optimizada que comprende los aminoacidos esenciales para la nutricion humana.
WO2000027374A3 (en) The use of excitatory amino acid transporter inhibitors to reduce cns white matter injury
WO1998050423A3 (fr) Analogues peptidiques et leurs utilisations notamment dans des compositions pharmaceutiques et pour le diagnostic
WO2004056863A8 (en) Splice variant of human placental growth hormone
WO2003089461A3 (en) Purified dutpase from helicobacter pylori
WO2002010380A1 (fr) Nouveau polypeptide, proteine a doigt de zinc de type kruppel zk110.12, et polynucleotide codant ce polypeptide
WO2000020572A3 (de) Gewebebindende peptide, ihre identifizierung, herstellung und verwendung
WO2002050116A3 (en) Adhesion molecule protein

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130730