HK1005026A1 - Process for the synthesis of (4r-cis)-1, 1-dimethylethyl-6-cyanomethyl-2, 2-dimethyl-1, 3-dioxane-4-acetate - Google Patents

Process for the synthesis of (4r-cis)-1, 1-dimethylethyl-6-cyanomethyl-2, 2-dimethyl-1, 3-dioxane-4-acetate Download PDF

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Publication number
HK1005026A1
HK1005026A1 HK98104173A HK98104173A HK1005026A1 HK 1005026 A1 HK1005026 A1 HK 1005026A1 HK 98104173 A HK98104173 A HK 98104173A HK 98104173 A HK98104173 A HK 98104173A HK 1005026 A1 HK1005026 A1 HK 1005026A1
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HK
Hong Kong
Prior art keywords
compound
formula
dimethyl
acetate
dioxane
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HK98104173A
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German (de)
English (en)
French (fr)
Chinese (zh)
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HK1005026B (en
Inventor
Millar Alan
Eugene Butler Donald
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沃纳-兰伯特公司
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Application filed by 沃纳-兰伯特公司 filed Critical 沃纳-兰伯特公司
Publication of HK1005026B publication Critical patent/HK1005026B/en
Publication of HK1005026A1 publication Critical patent/HK1005026A1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
HK98104173A 1990-10-17 1994-09-11 Process for the synthesis of (4r-cis)-1, 1-dimethylethyl-6-cyanomethyl-2, 2-dimethyl-1, 3-dioxane-4-acetate HK1005026A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US599521 1990-10-17
US07/599,521 US5103024A (en) 1990-10-17 1990-10-17 Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
PCT/US1991/006697 WO1992006968A1 (en) 1990-10-17 1991-09-11 Process for the synthesis of (4r-cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Publications (2)

Publication Number Publication Date
HK1005026B HK1005026B (en) 1998-12-18
HK1005026A1 true HK1005026A1 (en) 1998-12-18

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
HK98104173A HK1005026A1 (en) 1990-10-17 1994-09-11 Process for the synthesis of (4r-cis)-1, 1-dimethylethyl-6-cyanomethyl-2, 2-dimethyl-1, 3-dioxane-4-acetate

Country Status (20)

Country Link
US (1) US5103024A (cs)
EP (1) EP0553213B1 (cs)
JP (1) JP3105923B2 (cs)
KR (1) KR0166385B1 (cs)
AT (1) ATE118772T1 (cs)
AU (1) AU646311B2 (cs)
CA (1) CA2092997C (cs)
CZ (5) CZ282922B6 (cs)
DE (1) DE69107622T2 (cs)
DK (1) DK0553213T3 (cs)
ES (1) ES2070519T3 (cs)
FI (1) FI108539B (cs)
HK (1) HK1005026A1 (cs)
HU (2) HU219237B (cs)
IE (1) IE62940B1 (cs)
NO (1) NO301588B1 (cs)
PT (1) PT99244B (cs)
RU (1) RU2067580C1 (cs)
SK (5) SK280938B6 (cs)
WO (1) WO1992006968A1 (cs)

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HU227124B1 (en) * 2001-09-14 2010-07-28 Egis Gyogyszergyar Nyilvanosan Polymorphs of 1-pyrrole derivative, intermediate for the preparation of atorvastatin
UA77990C2 (en) * 2001-12-12 2007-02-15 Crystalline calcium salt of (2:1) [r-(r*,r*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrroleheptanic acid
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CZ296967B6 (cs) * 2002-02-01 2006-08-16 Zentiva, A.S. Zpusob výroby amorfní formy hemivápenaté soli (3R,5R) 7-[3-fenyl-4-fenylkarbamoyl-2-(4-fluorfenyl)-5-isopropylpyrrol-1-yl]-3,5-dihydroxyheptanové kyseliny (atorvastatinu)
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RU2337905C2 (ru) * 2003-04-14 2008-11-10 Уорнер-Ламберт Компани Ллс Способ получения фениламида 5-(4-фторфенил)-1-[2-((2r,4r)-4-гидрокси-6-оксотетрагидропиран-2-ил)этил]-2-изопропил-4-фенил-1h-пиррол-3-карбоновой кислоты
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Also Published As

Publication number Publication date
DE69107622D1 (de) 1995-03-30
HU219237B (en) 2001-03-28
IE913629A1 (en) 1992-04-22
FI931680A0 (fi) 1993-04-14
CZ209495A3 (en) 1997-12-17
JP3105923B2 (ja) 2000-11-06
WO1992006968A1 (en) 1992-04-30
HU9701183D0 (en) 1997-09-29
CZ124597A3 (en) 1997-12-17
PT99244A (pt) 1992-09-30
CA2092997A1 (en) 1992-04-18
CA2092997C (en) 2002-05-14
US5103024A (en) 1992-04-07
FI931680L (fi) 1993-04-14
EP0553213A1 (en) 1993-08-04
NO931421L (no) 1993-06-16
FI108539B (fi) 2002-02-15
HU213731B (en) 1997-09-29
NO301588B1 (no) 1997-11-17
AU646311B2 (en) 1994-02-17
CZ61493A3 (en) 1994-02-16
SK280938B6 (sk) 2000-09-12
DE69107622T2 (de) 1995-07-06
SK280942B6 (sk) 2000-09-12
SK280941B6 (sk) 2000-09-12
RU2067580C1 (ru) 1996-10-10
IE62940B1 (en) 1995-03-08
CZ282993B6 (cs) 1997-12-17
ES2070519T3 (es) 1995-06-01
HU9301122D0 (en) 1993-08-30
KR0166385B1 (en) 1999-01-15
NO931421D0 (no) 1993-04-16
KR930702328A (ko) 1993-09-08
EP0553213B1 (en) 1995-02-22
HUT64049A (en) 1993-11-29
AU8848091A (en) 1992-05-20
CZ124797A3 (en) 1997-12-17
SK280940B6 (sk) 2000-09-12
JPH06502162A (ja) 1994-03-10
ATE118772T1 (de) 1995-03-15
PT99244B (pt) 1999-04-30
CZ124697A3 (en) 1997-12-17
CZ282994B6 (cs) 1997-12-17
SK280939B6 (sk) 2000-09-12
CZ282992B6 (cs) 1997-12-17
CZ283003B6 (cs) 1997-12-17
SK33993A3 (en) 1993-10-06
CZ282922B6 (cs) 1997-11-12
DK0553213T3 (da) 1995-07-17

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