FI119691B - Puriinien valmistus - Google Patents

Puriinien valmistus Download PDF

Info

Publication number
FI119691B
FI119691B FI964193A FI964193A FI119691B FI 119691 B FI119691 B FI 119691B FI 964193 A FI964193 A FI 964193A FI 964193 A FI964193 A FI 964193A FI 119691 B FI119691 B FI 119691B
Authority
FI
Finland
Prior art keywords
formula
compound
preparation
amino
alkyl
Prior art date
Application number
FI964193A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI964193A (fi
FI964193A0 (fi
Inventor
John Robert Mansfield Dales
Original Assignee
Novartis Int Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Int Pharm Ltd filed Critical Novartis Int Pharm Ltd
Publication of FI964193A0 publication Critical patent/FI964193A0/fi
Publication of FI964193A publication Critical patent/FI964193A/fi
Application granted granted Critical
Publication of FI119691B publication Critical patent/FI119691B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Chemical Treatment Of Metals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI964193A 1994-04-19 1996-10-18 Puriinien valmistus FI119691B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9407698 1994-04-19
GB9407698A GB9407698D0 (en) 1994-04-19 1994-04-19 Pharmaceuticals
EP9501840 1995-04-19
PCT/EP1995/001840 WO1995028402A2 (en) 1994-04-19 1995-04-19 Preparation of purines

Publications (3)

Publication Number Publication Date
FI964193A0 FI964193A0 (fi) 1996-10-18
FI964193A FI964193A (fi) 1996-12-18
FI119691B true FI119691B (fi) 2009-02-13

Family

ID=10753741

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964193A FI119691B (fi) 1994-04-19 1996-10-18 Puriinien valmistus

Country Status (40)

Country Link
US (2) US6846927B1 (xx)
EP (1) EP0756597B1 (xx)
JP (1) JP3936734B2 (xx)
KR (1) KR100327147B1 (xx)
CN (1) CN1045963C (xx)
AP (2) AP582A (xx)
AT (1) ATE201209T1 (xx)
AU (1) AU691000B2 (xx)
BG (1) BG63464B1 (xx)
BR (1) BR9507494A (xx)
CA (1) CA2188181C (xx)
CZ (1) CZ287674B6 (xx)
DE (1) DE69520945T2 (xx)
DK (1) DK0756597T3 (xx)
DZ (1) DZ1872A1 (xx)
EG (1) EG20938A (xx)
ES (1) ES2158948T3 (xx)
FI (1) FI119691B (xx)
GB (1) GB9407698D0 (xx)
GR (1) GR3036338T3 (xx)
HK (1) HK1012348A1 (xx)
HU (1) HU226209B1 (xx)
IL (1) IL113409A (xx)
IN (1) IN183830B (xx)
MA (1) MA23518A1 (xx)
MX (1) MX9604942A (xx)
MY (1) MY128846A (xx)
NO (1) NO315000B1 (xx)
NZ (1) NZ287858A (xx)
OA (1) OA10376A (xx)
PL (1) PL181219B1 (xx)
PT (1) PT756597E (xx)
RO (1) RO118950B1 (xx)
RU (1) RU2158266C2 (xx)
SA (1) SA95150619B1 (xx)
SK (1) SK283193B6 (xx)
TW (1) TW311138B (xx)
UA (1) UA47401C2 (xx)
WO (1) WO1995028402A2 (xx)
ZA (1) ZA953110B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9807116D0 (en) 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
GB9807114D0 (en) 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
AU2003268213A1 (en) * 2002-08-26 2004-03-11 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
US20040266795A1 (en) * 2003-04-30 2004-12-30 Genny Shamai Process for the preparation of famciclovir
US20050143400A1 (en) * 2003-09-04 2005-06-30 Genny Shamai Process for preparing famciclovir
US7458839B2 (en) * 2006-02-21 2008-12-02 Fci Americas Technology, Inc. Electrical connectors having power contacts with alignment and/or restraining features
US20050215787A1 (en) * 2004-03-26 2005-09-29 Joshi Ramesh A An improved process for the preparation of purines
JP2007538087A (ja) * 2004-05-18 2007-12-27 テバ ファーマシューティカル インダストリーズ リミティド 結晶固形ファムシクロビルを調製するための乾燥方法
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
CN102070636B (zh) * 2011-01-17 2012-05-23 浙江大学 喷昔洛韦的制备方法
CN104086552B (zh) * 2014-07-31 2016-01-13 济南兆康医药科技有限公司 一种喷昔洛韦的精制方法
CN104496991A (zh) * 2014-11-04 2015-04-08 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3–羟甲基丁基)嘌呤的制备方法
CN104744472A (zh) * 2015-03-12 2015-07-01 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3-羟甲基丁基)嘌呤的制备方法
CN108314685B (zh) * 2018-03-16 2020-08-25 上药康丽(常州)药业有限公司 一种2-氨基-6-氯-9-(4-乙酰氧基-3-乙酰氧甲基丁基)嘌呤的制备方法
CN110713490A (zh) * 2018-07-12 2020-01-21 浙江医药股份有限公司新昌制药厂 一种喷昔洛韦的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0141927B1 (en) * 1983-08-18 1991-10-30 Beecham Group Plc Antiviral guanine derivatives
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
ES2098219T3 (es) * 1987-08-01 1997-05-01 Beecham Group Plc Compuestos de purina y su preparacion.
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
GB8822236D0 (en) * 1988-09-21 1988-10-26 Beecham Group Plc Chemical process

Also Published As

Publication number Publication date
ZA953110B (en) 1996-05-20
FI964193A (fi) 1996-12-18
WO1995028402A2 (en) 1995-10-26
DK0756597T3 (da) 2001-08-20
MY128846A (en) 2007-02-28
FI964193A0 (fi) 1996-10-18
CA2188181C (en) 2007-04-17
GB9407698D0 (en) 1994-06-15
NO315000B1 (no) 2003-06-23
NO964395L (no) 1996-10-15
IN183830B (xx) 2000-04-29
DZ1872A1 (fr) 2002-02-17
WO1995028402A3 (en) 1996-01-25
HK1012348A1 (en) 1999-07-30
US7355043B2 (en) 2008-04-08
EG20938A (en) 2000-06-28
HU226209B1 (en) 2008-06-30
CZ305396A3 (en) 1997-06-11
PL181219B1 (pl) 2001-06-29
SA95150619B1 (ar) 2005-05-04
RU2158266C2 (ru) 2000-10-27
NZ287858A (en) 1998-06-26
US6846927B1 (en) 2005-01-25
AU2670695A (en) 1995-11-10
EP0756597B1 (en) 2001-05-16
IL113409A (en) 1999-08-17
JPH09512000A (ja) 1997-12-02
CA2188181A1 (en) 1995-10-26
DE69520945D1 (de) 2001-06-21
BG63464B1 (bg) 2002-02-28
AP9500730A0 (en) 1995-04-30
CN1045963C (zh) 1999-10-27
HU9602891D0 (en) 1996-12-30
US20050101570A1 (en) 2005-05-12
AP582A (en) 1997-04-09
AP703A (en) 1998-12-04
HUT75339A (en) 1997-05-28
AU691000B2 (en) 1998-05-07
KR970702280A (ko) 1997-05-13
KR100327147B1 (ko) 2002-07-27
CN1150427A (zh) 1997-05-21
PT756597E (pt) 2001-11-30
ATE201209T1 (de) 2001-06-15
OA10376A (en) 2001-11-20
MX9604942A (es) 1998-05-31
GR3036338T3 (en) 2001-11-30
DE69520945T2 (de) 2002-03-28
UA47401C2 (uk) 2002-07-15
JP3936734B2 (ja) 2007-06-27
BR9507494A (pt) 1997-08-12
SK133296A3 (en) 1997-05-07
RO118950B1 (ro) 2004-01-30
IL113409A0 (en) 1995-07-31
MA23518A1 (fr) 1995-12-31
SK283193B6 (sk) 2003-03-04
ES2158948T3 (es) 2001-09-16
PL316943A1 (en) 1997-02-17
CZ287674B6 (en) 2001-01-17
NO964395D0 (no) 1996-10-15
AP9600870A0 (en) 1996-10-31
TW311138B (xx) 1997-07-21
BG100926A (en) 1997-07-31
EP0756597A1 (en) 1997-02-05

Similar Documents

Publication Publication Date Title
FI119691B (fi) Puriinien valmistus
JP7153705B2 (ja) Btk阻害剤を調製するプロセス
JP2009503034A (ja) 7H−ピロロ[2,3−d]ピリミジン誘導体の製造方法
CN109456329B (zh) 一种泛昔洛韦的制备方法
JPS62120386A (ja) プテリジン誘導体の製造方法
EP0915874A2 (en) Process of preparation of valacyclovir and relevant intermediates
JPH03153689A (ja) 5―メチル―N―(アリール)―1,2,4―トリアゾロ〔1,5―a〕ピリミジン―2―スルホンアミドの水性製造方法
WO2000006573A1 (en) Antiviral alkyl substituted purine derivatives and their preparation
CN102471292A (zh) 取代的3-氨基-5-氧代-4,5-二氢-[1,2,4]三氮烯的方法
CN111574463B (zh) 一种利格列汀中间体化合物ⅳ
JP2002530282A (ja) 改良された7−アザインドリル−3−カルボン酸の製造方法
KR930010559B1 (ko) 1-히드록시알킬크산틴류, 그의 제조방법
KR101372788B1 (ko) 고순도의 페메트렉시드 이나트륨 염의 제조방법
JPH03279348A (ja) 2,4,5―トリフルオロ―3―アルコキシ安息香酸の製造方法
AU2005230922A1 (en) Crystalline forms of 5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6H-dipyrido[3,2-B:2',3'-E][1,4]diazepin-6-one
JP2003500333A (ja) 4−[(2’,5’−ジアミノ−6’−ハロゲンピリミジン−4’−イル)アミノ]シクロペント−2−エンイルメタノールの製造方法
JP2002533343A (ja) N6−置換デアザアデノシン誘導体を製造する方法
JPH0212231B2 (xx)
JPH05255211A (ja) 2−アミノベンズアルデヒドの製法
JPS60184066A (ja) 5−フルオロ−6−クロロウラシル誘導体及びその製造方法
Hirota et al. Pyrimidine derivatives and related compounds. Part 50. Photochemical reaction of 5-substituted 6-azido-1, 3-dimethyluracils with nucleophiles. Ring transformation of pyrimidine to 1, 3, 5-triazepine and hydantoin ring systems
Ikaunieks et al. Synthesis of novel 2‐amino‐6, 8‐dithioxopurine derivatives
PL165170B1 (pl) Sposób wytwarzania 2,4-diamino-6-hydroksy-5-nitrozopirymidyny
JPH0699433B2 (ja) 5,6−ジヒドロプテリジン化合物
JPH11511440A (ja) カルボキシメチレンアントラニル酸のモノエステルおよびそれの製造方法

Legal Events

Date Code Title Description
FG Patent granted

Ref document number: 119691

Country of ref document: FI

MA Patent expired