FI104311B1 - Annosinhalointilaite ja -menetelmä - Google Patents

Annosinhalointilaite ja -menetelmä

Info

Publication number
FI104311B1
FI104311B1 FI924216A FI924216A FI104311B1 FI 104311 B1 FI104311 B1 FI 104311B1 FI 924216 A FI924216 A FI 924216A FI 924216 A FI924216 A FI 924216A FI 104311 B1 FI104311 B1 FI 104311B1
Authority
FI
Finland
Prior art keywords
loaded
piston
drug
sudden
liquid
Prior art date
Application number
FI924216A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI924216A0 (fi
FI104311B (fi
FI924216A (fi
Inventor
Terence Edward Weston
Stephen Terence Dunne
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909006340A external-priority patent/GB9006340D0/en
Priority claimed from GB909023767A external-priority patent/GB9023767D0/en
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of FI924216A0 publication Critical patent/FI924216A0/fi
Publication of FI924216A publication Critical patent/FI924216A/fi
Application granted granted Critical
Publication of FI104311B publication Critical patent/FI104311B/fi
Publication of FI104311B1 publication Critical patent/FI104311B1/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/26—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/26—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets
    • B05B1/262—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets with fixed deflectors
    • B05B1/265—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets with fixed deflectors the liquid or other fluent material being symmetrically deflected about the axis of the nozzle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0041—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure without contact of the fluid remaining in the container with the atmospheric air
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • B05B11/026—Membranes separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001—Piston pumps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1073—Springs
    • B05B11/1074—Springs located outside pump chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
    • B05B11/1091—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring being first hold in a loaded state by locking means or the like, then released
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B15/00—Details of spraying plant or spraying apparatus not otherwise provided for; Accessories
    • B05B15/40—Filters located upstream of the spraying outlets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B9/00—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour
    • B05B9/03—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material
    • B05B9/04—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material with pressurised or compressible container; with pump
    • B05B9/08—Apparatus to be carried on or by a person, e.g. of knapsack type
    • B05B9/085—Apparatus to be carried on or by a person, e.g. of knapsack type with a liquid pump
    • B05B9/0877—Apparatus to be carried on or by a person, e.g. of knapsack type with a liquid pump the pump being of pressure-accumulation type or being connected to a pressure accumulation chamber
    • B05B9/0883—Apparatus to be carried on or by a person, e.g. of knapsack type with a liquid pump the pump being of pressure-accumulation type or being connected to a pressure accumulation chamber having a discharge device fixed to the container
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
    • G01F11/025—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type with manually operated pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/34—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl
    • B05B1/3405—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl
    • B05B1/341—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet
    • B05B1/3421—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet with channels emerging substantially tangentially in the swirl chamber
    • B05B1/3431—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet with channels emerging substantially tangentially in the swirl chamber the channels being formed at the interface of cooperating elements, e.g. by means of grooves
    • B05B1/3436—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet with channels emerging substantially tangentially in the swirl chamber the channels being formed at the interface of cooperating elements, e.g. by means of grooves the interface being a plane perpendicular to the outlet axis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nozzles (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Special Spraying Apparatus (AREA)
  • Lift-Guide Devices, And Elevator Ropes And Cables (AREA)
  • Massaging Devices (AREA)
  • Disintegrating Or Milling (AREA)
  • Crushing And Grinding (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Pinball Game Machines (AREA)
  • External Artificial Organs (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Electrostatic Spraying Apparatus (AREA)
  • Valve Device For Special Equipments (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surgical Instruments (AREA)
  • Heat Treatment Of Water, Waste Water Or Sewage (AREA)
  • Colloid Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
FI924216A 1990-03-21 1992-09-21 Annosinhalointilaite ja -menetelmä FI104311B1 (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB909006340A GB9006340D0 (en) 1990-03-21 1990-03-21 Metered dose aerosol delivery system
GB9006340 1990-03-21
GB9023767 1990-11-01
GB909023767A GB9023767D0 (en) 1990-11-01 1990-11-01 Atomising devices and methods
PCT/GB1991/000433 WO1991014468A1 (en) 1990-03-21 1991-03-21 Atomising devices and methods
GB9100433 1991-03-21

Publications (4)

Publication Number Publication Date
FI924216A0 FI924216A0 (fi) 1992-09-21
FI924216A FI924216A (fi) 1992-09-21
FI104311B FI104311B (fi) 1999-12-31
FI104311B1 true FI104311B1 (fi) 1999-12-31

Family

ID=26296818

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924216A FI104311B1 (fi) 1990-03-21 1992-09-21 Annosinhalointilaite ja -menetelmä

Country Status (37)

Country Link
US (2) US5497944A (de)
EP (2) EP0627230B1 (de)
JP (1) JP2630347B2 (de)
KR (1) KR0139652B1 (de)
CN (2) CN1042203C (de)
AT (2) ATE160947T1 (de)
AU (1) AU650870B2 (de)
BR (1) BR9106249A (de)
CA (2) CA2206753C (de)
CZ (1) CZ283820B6 (de)
DE (2) DE69131966T2 (de)
DK (2) DK0627230T3 (de)
ES (2) ES2109943T3 (de)
FI (1) FI104311B1 (de)
GB (1) GB2256805B (de)
GR (2) GR3026065T3 (de)
HK (1) HK1005059A1 (de)
HR (1) HRP921357B1 (de)
HU (1) HU216121B (de)
IE (1) IE62626B1 (de)
IL (1) IL97619A (de)
IN (1) IN177383B (de)
MY (1) MY110310A (de)
NO (1) NO303206B1 (de)
NZ (1) NZ237502A (de)
PH (1) PH30833A (de)
PL (1) PL165926B1 (de)
PT (1) PT97098B (de)
RS (1) RS49548B (de)
RU (1) RU2104048C1 (de)
SG (1) SG45171A1 (de)
SI (1) SI9110500B (de)
SK (1) SK280225B6 (de)
TW (1) TW253846B (de)
UA (1) UA27777C2 (de)
WO (1) WO1991014468A1 (de)
YU (1) YU48710B (de)

Families Citing this family (408)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100224A (en) * 1990-12-04 1994-10-21 Dmw Tech Ltd Spray nozzle
US6540154B1 (en) * 1991-04-24 2003-04-01 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
GB9114080D0 (en) * 1991-06-28 1991-08-14 Weston Terence E Atomising valve
ES2099266T5 (es) * 1991-07-01 2004-01-01 Alexander George Brian O'neil Aparato de infusion controlada por el paciente.
US5546932A (en) * 1992-03-25 1996-08-20 Tebro Sa Powder jet dispenser for medicament inhalation therapies
IL107120A (en) 1992-09-29 1997-09-30 Boehringer Ingelheim Int Atomising nozzle and filter and spray generating device
US6007676A (en) * 1992-09-29 1999-12-28 Boehringer Ingelheim International Gmbh Atomizing nozzle and filter and spray generating device
US6012450A (en) * 1993-01-29 2000-01-11 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5724957A (en) * 1993-01-29 1998-03-10 Aradigm Corporation Intrapulmonary delivery of narcotics
US5558085A (en) * 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US6098620A (en) * 1993-01-29 2000-08-08 Aradigm Corporation Device for aerosolizing narcotics
US6131567A (en) * 1993-01-29 2000-10-17 Aradigm Corporation Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin
US5915378A (en) * 1993-01-29 1999-06-29 Aradigm Corporation Creating an aerosolized formulation of insulin
US5672581A (en) * 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
US5970973A (en) * 1993-01-29 1999-10-26 Aradigm Corporation Method of delivering insulin lispro
US5819726A (en) * 1993-01-29 1998-10-13 Aradigm Corporation Method for the delivery of aerosolized drugs to the lung for the treatment of respiratory disease
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US5873358A (en) * 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US5507277A (en) * 1993-01-29 1996-04-16 Aradigm Corporation Lockout device for controlled release of drug from patient-activateddispenser
US5694919A (en) * 1993-01-29 1997-12-09 Aradigm Corporation Lockout device for controlled release of drug from patient-activated dispenser
US5934272A (en) * 1993-01-29 1999-08-10 Aradigm Corporation Device and method of creating aerosolized mist of respiratory drug
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
DK48993D0 (da) * 1993-04-30 1993-04-30 Steen Erik Holm Forstoevningsapparat til vandbaaret lungemedicin
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
US5792057A (en) * 1993-05-21 1998-08-11 Aradigm Corporation Ventilation imaging using a fine particle aerosol generator
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
FR2705911B1 (fr) * 1993-06-02 1995-08-11 Oreal Appareil de nébulisation piézoélectrique.
EP0759744B1 (de) * 1994-05-13 2001-10-17 Aradigm Corporation Ein narkotikum enthaltende aerosolformulierung
DE4428434A1 (de) * 1994-08-11 1996-02-15 Boehringer Ingelheim Kg Verschlußkappe und Verfahren zur gasblasenfreien Füllung von Behältern
US5522385A (en) * 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
US6782886B2 (en) * 1995-04-05 2004-08-31 Aerogen, Inc. Metering pumps for an aerosolizer
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
AU710177B2 (en) * 1995-06-07 1999-09-16 Alexander George Brian O'neil Patient controlled drug delivery device
DE69637920D1 (de) 1995-06-07 2009-06-18 Oneil Alexander G B Vom Patienten gesteuerte Vorrichtung zur Arzneimittelabgabe
SE9503141D0 (sv) * 1995-09-12 1995-09-12 Siemens Elema Ab Narkosapparat
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
DE19545226C1 (de) 1995-12-05 1997-06-19 Boehringer Ingelheim Int Sperrspannwerk für einen federbetätigten Abtrieb
US5829436A (en) * 1996-02-05 1998-11-03 Aradigm Corporation Ventilation imaging using a fine particle aerosol generator
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
FR2745551B1 (fr) * 1996-02-29 1998-05-07 Kerplas Snc Capuchon-poussoir pour flacon de distribution d'un produit, et flacon correspondant
DE19615422A1 (de) * 1996-04-19 1997-11-20 Boehringer Ingelheim Kg Zweikammer-Kartusche für treibgasfreie Dosieraerosole
AUPO418696A0 (en) 1996-12-12 1997-01-16 Resmed Limited A substance delivery apparatus
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
US20030215396A1 (en) 1999-09-15 2003-11-20 Boehringer Ingelheim Pharma Kg Method for the production of propellant gas-free aerosols from aqueous medicament preparations
US5829435A (en) * 1997-02-24 1998-11-03 Aradigm Corporation Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles
GB9818111D0 (en) 1998-08-19 1998-10-14 Weston Medical Ltd Device for metered fluid delivery
US6089414A (en) 1997-03-06 2000-07-18 Hayes Products, Llc Pump assembly with one piece piston
US5918782A (en) * 1997-03-06 1999-07-06 Hayes Products, Llc Pump assembly with sprayer
US5810211A (en) * 1997-03-06 1998-09-22 Hayes Products, Llc Pump assembly with sliding plug
US5816447A (en) * 1997-03-06 1998-10-06 Hayes Products, Llc Non-aerosol pump spray apparatus
DE19715893C2 (de) * 1997-04-16 1999-04-29 Boehringer Ingelheim Int Vorrichtung zum Entnehmen einer Flüssigkeit aus einem geschlossenen Behälter
DE19733651A1 (de) * 1997-08-04 1999-02-18 Boehringer Ingelheim Pharma Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole
US20060239930A1 (en) * 1997-08-04 2006-10-26 Herbert Lamche Process for nebulizing aqueous compositions containing highly concentrated insulin
USD418201S (en) * 1997-08-27 1999-12-28 Hayes Products, Llc Bottle, pump and sprayer assembly
USD417618S (en) * 1997-08-28 1999-12-14 Hayes Products, Llc Pump assembly
DE19742439C1 (de) 1997-09-26 1998-10-22 Boehringer Ingelheim Int Mikrostrukturiertes Filter
US6016800A (en) * 1997-10-24 2000-01-25 Century; Theodore J. Intrapulmonary aerosolizer
GB9724223D0 (en) * 1997-11-18 1998-01-14 Pa Consulting Services Drug delivery device
US6223746B1 (en) * 1998-02-12 2001-05-01 Iep Pharmaceutical Devices Inc. Metered dose inhaler pump
US7963955B2 (en) * 1998-02-27 2011-06-21 Boehringer Ingelheim International Gmbh Container for a medicinal liquid
US7335186B2 (en) 1998-03-13 2008-02-26 Alexander George Brian O'Neil Patient controlled drug delivery device
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen
US6745763B2 (en) * 1998-10-27 2004-06-08 Garth T. Webb Vaporizing device for administering sterile medication
DE19851404A1 (de) 1998-11-07 2000-05-11 Boehringer Ingelheim Int Druckausgleichsvorrichtung für einen Doppelbehälter
US6354516B1 (en) * 1999-11-02 2002-03-12 Aradigm Corporation Pore structures for reduced pressure aerosolization
US6070575A (en) * 1998-11-16 2000-06-06 Aradigm Corporation Aerosol-forming porous membrane with certain pore structure
AU1473000A (en) 1998-11-16 2000-06-05 Aradigm Corporation Method of fabricating porous membrane with unique pore structure for aerosolizeddelivery of drugs
WO2000041814A1 (en) * 1999-01-11 2000-07-20 Graves Spray Supply, Inc. Liquid impingement nozzle with paired openings
DE19940713A1 (de) * 1999-02-23 2001-03-01 Boehringer Ingelheim Int Kartusche für eine Flüssigkeit
DE19921693A1 (de) 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
US6360922B1 (en) 1999-04-27 2002-03-26 Hayes Products, Llc Pump assembly with pressure release capability
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US6235177B1 (en) * 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
ATE345875T1 (de) * 1999-09-15 2006-12-15 Aradigm Corp Porenstrukturen zur niederdruckaerosolisierung
EP1747816A3 (de) * 1999-09-15 2007-02-14 Aradigm Corporation Poren Struktur zur Niederdruckzerstäubung
SE9903990D0 (sv) * 1999-11-02 1999-11-02 Shl Medical Ab Inhalator with aerosolizing unit
GB0002798D0 (en) * 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
US6948491B2 (en) * 2001-03-20 2005-09-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
MXPA02010884A (es) * 2000-05-05 2003-03-27 Aerogen Ireland Ltd Aparato y metodo para el suministro de medicamentos al sistema respiratorio.
US7600511B2 (en) * 2001-11-01 2009-10-13 Novartis Pharma Ag Apparatus and methods for delivery of medicament to a respiratory system
US6968840B2 (en) 2000-05-05 2005-11-29 Aerogen, Inc. Methods and systems for operating an aerosol generator
US7971588B2 (en) * 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US8336545B2 (en) * 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
GB0012356D0 (en) 2000-05-22 2000-07-12 Textron Automotive Company Lim Fluid spray nozzle
US6325248B1 (en) 2000-07-05 2001-12-04 Robert E. Corba Container assembly
US6299024B1 (en) 2000-07-05 2001-10-09 Robert E. Corba Valve assembly for dispensing container
KR100492671B1 (ko) * 2000-10-05 2005-06-07 오므론 헬스캐어 가부시키가이샤 액체 무화 장치
AU2173802A (en) * 2000-10-31 2002-05-15 Boehringer Ingelheim Pharma Inhalative solution formulation containing a tiotropium salt
US20020084290A1 (en) * 2000-11-10 2002-07-04 Therics, Inc. Method and apparatus for dispensing small volume of liquid, such as with a weting-resistant nozzle
AU2002216489A1 (en) * 2000-12-11 2002-06-24 Fenton, Colleen Mary An inflation device
DE10062630A1 (de) * 2000-12-15 2002-08-29 Bartels Mikrotechnik Gmbh Beduftungsverfahren
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US20110301569A1 (en) 2001-01-20 2011-12-08 Gordon Wayne Dyer Methods and apparatus for the CVCS
US6550472B2 (en) * 2001-03-16 2003-04-22 Aerogen, Inc. Devices and methods for nebulizing fluids using flow directors
US6732944B2 (en) * 2001-05-02 2004-05-11 Aerogen, Inc. Base isolated nebulizing device and methods
GB0111336D0 (en) * 2001-05-10 2001-07-04 Innovata Biomed Ltd Device
DE10125564A1 (de) 2001-05-25 2002-11-28 Transmit Technologietransfer Inhalationsmaske für Pferde
FR2826344B1 (fr) * 2001-06-22 2003-09-05 Oreal Dispositif pour la pulverisation d'un produit, notamment sous forme de dose echantillon
DE10131178A1 (de) * 2001-06-29 2003-01-16 Boehringer Ingelheim Pharma Vernebler zur Applikation von Flüssigkeiten in die Augen
DE10136555A1 (de) 2001-07-27 2003-02-13 Boehringer Ingelheim Int Optimierte Verfahren zur Bestimmung der Aerosol-Partikelgrößenverteilung und Vorrichtung zur Durchführung derartiger Verfahren
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US7231919B2 (en) * 2001-09-28 2007-06-19 Kurve Technology, Inc. Particle dispersion device for nasal delivery
DE10154237A1 (de) * 2001-11-07 2003-05-15 Steag Microparts Gmbh Zerstäuber für manuelle Betätigung
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6804458B2 (en) 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
US20030178022A1 (en) * 2001-12-21 2003-09-25 Chiesi Farmaceutici S.P.A. Pressurized metered dose inhaler (PMDI) actuators and medicinal aerosol solution formulation products comprising therse actuators
DE10163500A1 (de) * 2001-12-21 2002-12-19 Wella Ag Versprühbare Haargele
US20050205089A1 (en) * 2002-01-07 2005-09-22 Aerogen, Inc. Methods and devices for aerosolizing medicament
US7677467B2 (en) * 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
AU2003202925B2 (en) * 2002-01-07 2008-12-18 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US6868851B2 (en) * 2002-01-31 2005-03-22 Instrumentarium Corp. Liquid reservoir for nebulizer
US6953133B2 (en) * 2002-04-02 2005-10-11 Hayes Products, Inc. Pump assembly with continuous tube
DE10216036A1 (de) 2002-04-11 2003-10-23 Boehringer Ingelheim Pharma Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz
DE10216429A1 (de) 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Arzneimittel enthaltend Steroide und ein neues Anticholinergikum
US8122881B2 (en) * 2002-05-09 2012-02-28 Kurve Technology, Inc. Particle dispersion device for nasal delivery
WO2003097126A2 (en) * 2002-05-20 2003-11-27 Aerogen, Inc. Aerosol for medical treatment and methods
US20070044792A1 (en) * 2005-08-30 2007-03-01 Aerogen, Inc. Aerosol generators with enhanced corrosion resistance
DE20221948U1 (de) 2002-06-08 2009-09-24 Boehringer Ingelheim International Gmbh Vernebler mit Merkhilfe für das Therapieregiment
EP1707205A2 (de) 2002-07-09 2006-10-04 Boehringer Ingelheim Pharma GmbH & Co. KG Pharazeutische zusammensetzungen aus anticholinergica und p38 kinase hemmern zur behandlung von erkrankungen der atemwege
DE10230751A1 (de) 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern
GB0217866D0 (en) * 2002-08-01 2002-09-11 Steag Microparts Gmbh Low dose spray pump
GB2391862C (en) * 2002-08-13 2007-01-11 Shield Medicare Ltd Spray dispenser assembly and vessel therefor
ATE400265T1 (de) * 2002-08-14 2008-07-15 Boehringer Ingelheim Pharma Aerosolformulierung für die inhalation enthaltend ein anticholinergikum
US20040166065A1 (en) 2002-08-14 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation comprising an anticholinergic
US7699052B2 (en) * 2002-09-05 2010-04-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Apparatus for the dispensing of liquids, container cartridge suitable for this, and system comprising the apparatus for the dispensing of liquids, and the container cartridge
DE10243255A1 (de) 2002-09-17 2004-03-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zum Messen der Dichtigkeit von Folienbehältnissen
US20040055595A1 (en) * 2002-09-19 2004-03-25 Noymer Peter D. Aerosol drug delivery system employing formulation pre-heating
SE0202800D0 (sv) * 2002-09-23 2002-09-23 Pharmacia Ab Dispensing apparatus and method for liquid products, particularly medicinal products
US7481212B2 (en) * 2002-10-30 2009-01-27 Nektar Therapeutics Increased dosage metered dose inhaler
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
US7037535B2 (en) * 2002-11-19 2006-05-02 Kimberly-Clark Worldwide, Inc. Method and composition for neutralizing house dust mite feces
US7621266B2 (en) 2003-01-14 2009-11-24 Boehringer Ingelheim International Gmbh Nozzle-system for a dispenser for fluids consisting of a nozzle and a nozzle-holder and/or screw cap
DE10300983A1 (de) 2003-01-14 2004-07-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Düsensystem für eine Ausbringungsvorrichtung für Flüssigkeiten bestehend aus Düse und Düsenhalter und/oder Überwurfmutter
GB0300939D0 (en) * 2003-01-16 2003-02-12 Unilever Plc Method of creating a cosmetic spray
US7883031B2 (en) 2003-05-20 2011-02-08 James F. Collins, Jr. Ophthalmic drug delivery system
PT1644129E (pt) 2003-07-16 2007-01-31 Boehringer Ingelheim Pharma Processo de produção de configurações microfluídicas a partir de uma estrutura compósita em forma de placa
US8616195B2 (en) * 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
US20050017089A1 (en) * 2003-07-21 2005-01-27 Marc Rohrschneider Finger operated spray pump
PT1651270E (pt) 2003-07-29 2007-04-30 Boehringer Ingelheim Int Medicamentos para inalação compreendendo betamiméticos e um anticolinérgico
WO2005023334A2 (en) * 2003-09-05 2005-03-17 Kurve Technology, Inc. Nasal adapter for the base of the nose
US8001963B2 (en) * 2003-09-05 2011-08-23 Kurve Technology, Inc. Integrated nebulizer and particle dispersion chamber for nasal delivery of medicament to deep nasal cavity and paranasal sinuses
US7427004B2 (en) * 2003-10-20 2008-09-23 Meadwestvaco Calmar, Inc. Hand held pressurized sprayer
DE102004001451A1 (de) 2004-01-08 2005-08-11 Boehringer Ingelheim International Gmbh Vorrichtung zum Haltern eines fluidischen Bauteiles
DE102004009435A1 (de) 2004-02-24 2005-12-08 Boehringer Ingelheim International Gmbh Zerstäuber
DE102004009434A1 (de) 2004-02-24 2005-12-15 Boehringer Ingelheim International Gmbh Zerstäuber
DE102004009436A1 (de) 2004-02-24 2005-10-13 Boehringer Ingelheim International Gmbh Zerstäuber
WO2005079997A1 (de) 2004-02-24 2005-09-01 Boehringer Ingelheim International Gmbh Zerstäuber
DE102004011381A1 (de) * 2004-03-05 2005-09-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Impaktionsdüse für treibgasbetriebene Dosieraerosole
DE102004012093A1 (de) * 2004-03-05 2005-09-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Merkanaldüse
BE1015973A3 (fr) * 2004-04-09 2005-12-06 Oultremont Aurian D Dispositif de spray combine avec une poche souple a maintient vertical.
US7290541B2 (en) * 2004-04-20 2007-11-06 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
EP1740242A4 (de) * 2004-04-20 2009-12-23 Aerogen Inc Aerosolabgabevorrichtung, verfahren und zusammensetzungen für druckunterstützte atemsysteme
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
US7267121B2 (en) * 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US20050272726A1 (en) * 2004-04-22 2005-12-08 Boehringer Ingelheim International Gmbh Novel medicaments for the treatment of respiratory diseases
ES2380370T3 (es) 2004-04-22 2012-05-11 Boehringer Ingelheim International Gmbh Combinaciones farmacológicas que contienen benzoxazina para el tratamiento de enfermedades de las vías respiratorias
EP1745247B1 (de) 2004-04-23 2015-11-11 Philip Morris Products S.a.s. Aerosolgeneratoren und verfahren zur herstellung von aerosolen
DE102004021789A1 (de) * 2004-05-03 2006-04-27 Boehringer Ingelheim International Gmbh Zerstäuber zum Ausbringen von Flüssigkeiten für medizinische Zwecke
US7727962B2 (en) 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
US7611709B2 (en) 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7723306B2 (en) 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US20050255050A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Powder formulations for inhalation, comprising enantiomerically pure beta agonists
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
PL1891974T3 (pl) 2004-05-31 2010-12-31 Almirall Sa Kombinacje zawierające środki przeciwmuskarynowe i inhibitory PDE4
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
US7299950B2 (en) * 2004-09-03 2007-11-27 Rieke Corporation Dispensing apparatus
US7152813B2 (en) * 2004-09-13 2006-12-26 Ding Hwa Co., Ltd. Cap with a suction type spray head
AU2005291427A1 (en) 2004-10-06 2006-04-13 Boehringer Ingelheim International Gmbh Dispensing device, storage device and method for dispensing powder
EP1807136A2 (de) * 2004-10-12 2007-07-18 Aradigm Corporation Vorrichtung und verfahren zur erzeugung eines aerosols aus einer flüssigen formulierung und sicherstellung ihrer sterilität
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) * 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
DK2522365T3 (en) 2004-11-24 2017-02-06 Meda Pharmaceuticals Inc Compositions comprising azelastine and methods for its use
JP4715254B2 (ja) 2005-03-18 2011-07-06 オムロンヘルスケア株式会社 吸入器
CN100366347C (zh) * 2005-04-15 2008-02-06 池龙岩 全自动喷雾器
JP5087539B2 (ja) 2005-05-18 2012-12-05 ネクター セラピューティックス 気管支内治療のためのバルブ、デバイス、および方法
ES2265276B1 (es) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
DE102005024439A1 (de) 2005-05-24 2006-12-07 Boehringer Ingelheim International Gmbh Zerstäuber
MX2007014867A (es) * 2005-05-25 2008-02-21 Aerogen Inc Sistema y metodos de vibracion.
TWI366460B (en) 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
EP1898894A1 (de) * 2005-06-17 2008-03-19 Boehringer Ingelheim International GmbH Mrp-iv-hemmer zur behandlung von atemwegserkrankungen
DE102005029746B4 (de) * 2005-06-24 2017-10-26 Boehringer Ingelheim International Gmbh Zerstäuber
DE102005063657B3 (de) 2005-06-24 2022-11-03 Boehringer Ingelheim International Gmbh Zerstäuber und Behälter
WO2007000330A2 (en) 2005-06-29 2007-01-04 Boehringer Ingelheim International Gmbh Method and device for atomising liquid
DE102005030733A1 (de) 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
DE102005035715A1 (de) 2005-07-27 2007-02-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Überprüfung der Permeabilitätsrate eines geschlossenen Behälters
CA2619402C (en) * 2005-08-15 2015-02-03 Boehringer Ingelheim International Gmbh Method for producing betamimetics
JP5128476B2 (ja) 2005-08-24 2013-01-23 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アトマイザ
US20070086957A1 (en) 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
DE102005052898A1 (de) * 2005-11-03 2007-05-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren und Vorrichtung zum Dosieren von Arzneimitteln
US7423146B2 (en) 2005-11-09 2008-09-09 Boehringer Ingelheim International Gmbh Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
EP1792660A1 (de) 2005-12-02 2007-06-06 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
JP4731304B2 (ja) 2005-12-14 2011-07-20 Ｈｏｙａ株式会社 内視鏡用液体塗布具
JP4774290B2 (ja) 2005-12-19 2011-09-14 Ｈｏｙａ株式会社 内視鏡用液剤散布具
JP4674541B2 (ja) * 2005-12-22 2011-04-20 パナソニック電工株式会社 静電霧化装置及び静電霧化装置を備えた食品保管庫
US7958887B2 (en) * 2006-03-10 2011-06-14 Aradigm Corporation Nozzle pore configuration for intrapulmonary delivery of aerosolized formulations
TWM297751U (en) * 2006-03-21 2006-09-21 Taidoc Technology Corp Liquid nebulizer
DE102006016901A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102006022002A1 (de) 2006-05-10 2007-11-15 Boehringer Ingelheim International Gmbh Zerstäuber und Verfahren zur Zerstäubung von Fluid
CA2652699C (en) 2006-05-19 2014-11-04 Boehringer Ingelheim International Gmbh Propellant-free inhalation aerosol formulation containing ipratropium bromide and salbutamol sulfate
US8061350B2 (en) * 2006-06-02 2011-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process and device for dosing pharmaceutical agents
DE102006025871A1 (de) * 2006-06-02 2007-12-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber
US20090324510A1 (en) 2006-08-07 2009-12-31 Boehringer Ingelheim International Gmbh Drug combinations for the treatment of respiratory tract diseases
PE20080610A1 (es) 2006-08-22 2008-07-15 Boehringer Ingelheim Int Nuevos beta-agonistas enantiomericamente puros, procedimientos para su preparacion y uso como medicamentos
CA2698137A1 (en) 2006-08-30 2008-03-06 Kurve Technology, Inc. Aerosol generating and delivery device
NL1033149C2 (nl) * 2006-12-29 2008-07-01 Afa Polytek Bv Doseerinrichting die bestaat uit een houder met een hals en een door een klikkoppeling daarmee verbonden doseerkop.
ES2306595B1 (es) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
JP2010519963A (ja) * 2007-02-28 2010-06-10 アボツト・レスピラトリー・エル・エル・シー ノズル形式の噴霧システム
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
DE102007020578A1 (de) 2007-05-02 2008-11-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Wässrige Aerosolzubereitungen enthaltend therapeutisch wirksame Mikroorganismen oder Teile von Mikroorganismen und Verfahren zur Erzeugung entsprechender Aerosole
DE102007023012A1 (de) 2007-05-15 2008-11-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber und Filter
CA2686217A1 (en) 2007-06-15 2008-12-18 Boehringer Ingelheim International Gmbh Inhaler
EP2044967A1 (de) * 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Zerstäuber
ES2320961B1 (es) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
EP2077132A1 (de) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung
GB0800709D0 (en) * 2008-01-16 2008-02-20 Dunne Stephen T Double jet impinging nozzle
US9364841B2 (en) * 2008-02-19 2016-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Cartridge system
EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
EP2096105A1 (de) 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. 4-(2-Amino-1-hydroxyethyl)Phenol-Derivate als Agonisten des b2-adrenergen Rezeptors
US20090218412A1 (en) * 2008-02-29 2009-09-03 Sge Analytical Science Pty Ltd. Non-contact dispensing of liquid droplets
EP2100599A1 (de) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
EP2100598A1 (de) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
EP2108641A1 (de) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. Neue substituierte Spiro[Cycloalkyl-1,3'-indo]-2'(1'H)-on-Derivate und ihre Verwendung als p38 mitogen-activated Kinase Inhibitoren
DK2110132T3 (da) 2008-04-20 2014-04-28 D2 Bioscience Group Ltd Anvendelse af deuteriumoxid som elastasehæmmer
EP2113503A1 (de) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. Neue substituierte Indolin-2-on- Derivate und ihre Verwendung als p39 mitogen-activated Kinase Inhibitoren
EP2135632A1 (de) 2008-06-20 2009-12-23 Boehringer Ingelheim International Gmbh Inhalator
WO2010033207A1 (en) 2008-09-19 2010-03-25 Nektar Therapeutics Polymer conjugates of therapeutic peptides
US7984567B2 (en) * 2008-10-07 2011-07-26 Christ Bill Bertakis Apparatus for cleaning simulated hair articles
DE202008015493U1 (de) 2008-11-21 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Faltschachtel
EP2189224A1 (de) 2008-11-22 2010-05-26 Grundfos Management A/S Düse
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
AU2010260211B2 (en) 2008-12-22 2016-04-21 Acerus Pharmaceuticals USA, LLC Safe desmopressin administration
EP2393492A1 (de) 2009-02-09 2011-12-14 Boehringer Ingelheim International GmbH Neue pharmazeutische zusammensetzungen zur behandlung von atemwegs- und gastrointestinalen erkrankungen
EP2221297A1 (de) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-Difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxychinolin-2(1H)-on und seine Verwendung bei der Behandlung von Atemwegserkrankungen
EP2221055A1 (de) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one für die Behandlung von Lungenfunktion
EP2226323A1 (de) 2009-02-27 2010-09-08 Almirall, S.A. Neuartige Tetrahydropyrazol[3,4-c]isochinolin-5-amin-Derivate
EP2228368A1 (de) 2009-03-12 2010-09-15 Almirall, S.A. Verfahren zur Herstellung von 5-(2-{[6-(2,2-Difluor-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxychinolin-2(1H)-on
EP2236227B1 (de) 2009-03-30 2013-12-18 Boehringer Ingelheim International GmbH Umformwerkzeug mit einem rotierbaren Grundkörper
EP2236224B1 (de) 2009-03-30 2013-03-06 Boehringer Ingelheim International GmbH Umformwerkzeug mit einem rotierbaren Grundkörper zum Formen einer Inhalatorkartusche und Verwendung eines solchen Umformwerkzeugs
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
WO2010124795A1 (de) 2009-04-28 2010-11-04 Boehringer Ingelheim International Gmbh Inhalationsvorrichtung
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
LT2435025T (lt) 2009-05-29 2016-09-26 Pearl Therapeutics, Inc. Veikliosios medžiagos tiekimas per kvėpavimo takus
RU2452585C2 (ru) * 2009-06-03 2012-06-10 Макнейл Аб Карманное распределительное устройство
WO2011005645A1 (en) 2009-07-06 2011-01-13 Boehringer Ingelheim International Gmbh Polymorph of [4,6-bis(dimethylamino)-2-(4-{[4-(trifluoromethyl)benzoyl]amino}benzyl)pyrimidin-5-yl]
WO2011007272A1 (en) * 2009-07-16 2011-01-20 Koninklijke Philips Electronics, N.V. Single operation control mechanism for a pressurized gas oral cleaning appliance
CA2768379C (en) * 2009-07-17 2017-10-10 David Mark Blakey Negatively biased sealed nebulizers systems and methods
EP2322176A1 (de) 2009-11-11 2011-05-18 Almirall, S.A. Neue 7-Phenyl-[1,2,4]triazol[4,3-a]pyridin-3(2H)on-Derivate
WO2011066147A2 (en) 2009-11-24 2011-06-03 Boehringer Ingelheim International Gmbh Novel salt forms of pyrimidin-5-yl acetic acid derivative
EA201200765A1 (ru) 2009-11-24 2013-02-28 Бёрингер Ингельхайм Интернациональ Гмбх Способ получения полиморфной модификации холиновой соли производного пиримидин-5-илуксусной кислоты
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064164A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
EP2504051B1 (de) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Zerstäuber
US8464742B2 (en) * 2010-02-11 2013-06-18 Honeywell International Inc. Injection or other system with anti-thermal lockdown mechanism and related method
US8974771B2 (en) * 2010-03-09 2015-03-10 Penn-Century, Inc. Apparatus and method for aerosol delivery to the lungs or other locations of the body
EP2380890A1 (de) 2010-04-23 2011-10-26 Almirall, S.A. Neue 7,8-Dihydro-1,6-Naphthyridin-5(6H)-on-Derivate als PDE4 Inhibitoren
EP2386555A1 (de) 2010-05-13 2011-11-16 Almirall, S.A. Neue Cyclohexylaminderivate mit Aktivitäten von Beta2-adrenergem Agonisten und M3-Muskarin-Antagonisten
EP2394998A1 (de) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl Derivate als PDE4 Inhibitoren
WO2011154295A2 (de) 2010-06-08 2011-12-15 Boehringer Ingelheim International Gmbh Medizinisches gerät mit zählwerk mit voreingestelltem zählbereich gerät mit zählwerksvariation
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
WO2012009696A2 (en) 2010-07-15 2012-01-19 Corinthian Ophthalmic, Inc. Ophthalmic drug delivery
CA2805426C (en) 2010-07-15 2020-03-24 Corinthian Ophthalmic, Inc. Drop generating device
CA2805635A1 (en) 2010-07-15 2012-01-19 Corinthian Ophthalmic, Inc. Method and system for performing remote treatment and monitoring
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
US9283333B2 (en) 2010-07-16 2016-03-15 Boehringer Ingelheim International Gmbh Filter system for use in medical devices
RU2561570C2 (ru) * 2010-09-06 2015-08-27 Кьези Фармасьютичи С.П.А. Исполнительный механизм дозирующего ингалятора и дозирующий ингалятор
EP2441755A1 (de) 2010-09-30 2012-04-18 Almirall, S.A. Pyridin- und Isochinolin-Derivate als Syk- und JAK-Kinase-Inhibitors
EP2457900A1 (de) 2010-11-25 2012-05-30 Almirall, S.A. Neue Pyrazolderivate mit CRTH2-antagonistischem Verhalten
EP2463289A1 (de) 2010-11-26 2012-06-13 Almirall, S.A. Imidazo[1,2-b]Pyridazin-Derivate als AS JAK-Hemmer
EP2489663A1 (de) 2011-02-16 2012-08-22 Almirall, S.A. Verbindungen als Syk-Kinasehemmer
CN103917265B (zh) 2011-03-03 2017-02-15 英倍尔药业股份有限公司 鼻药递送装置
GB2489216B (en) * 2011-03-16 2013-08-07 Consort Medical Plc Fluid delivery device
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
EP2510928A1 (de) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten
EP2518070A1 (de) 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinonderivate als PI3K-Inhibitoren
EP2518071A1 (de) 2011-04-29 2012-10-31 Almirall, S.A. Imidazopyridinderivate als PI3K-Inhibitoren
US9458615B2 (en) 2011-05-13 2016-10-04 Conopco, Inc. Spraying device
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
EP2526945A1 (de) 2011-05-25 2012-11-28 Almirall, S.A. Neue CRTH2-Antagonisten
EP2527344A1 (de) 2011-05-25 2012-11-28 Almirall, S.A. Als Medikamente zur Behandlung von myeloproliferativen Krankheiten, Transplantatabstossung, immunbedingten und entzündlichen Erkrankungen geeignete Pyridin-2(1H-)-on-Derivate
CA2837057C (en) 2011-06-06 2018-08-28 Trudell Medical International Oscillating positive expiratory pressure device
EP2548876A1 (de) 2011-07-18 2013-01-23 Almirall, S.A. Neue CRTH2-Antagonisten
EP2548863A1 (de) 2011-07-18 2013-01-23 Almirall, S.A. Neue CRTH2-Antagonisten
EP2554544A1 (de) 2011-08-01 2013-02-06 Almirall, S.A. Pyridin-2(1H-)-on-Derivate als JAK-Inhibitoren
WO2013017393A1 (en) * 2011-08-03 2013-02-07 Unilever N.V. Spraying device
EP2578570A1 (de) 2011-10-07 2013-04-10 Almirall, S.A. Neues Verfahren zur Herstellung von 5-(2-{[6-(2,2-Difluor-2-phenylethoxy)hexyl]amino}-1(R)-hydroxyethyl)-8-hydroxychinolin-2(1H)-on mittels neuen Synthesezwischenstoffen
WO2013064690A1 (de) * 2011-11-04 2013-05-10 Chv Pharma Gmbh & Co. Kg Inhalator sowie verfahren zum erzeugen eines aerosols
EP2592078A1 (de) 2011-11-11 2013-05-15 Almirall, S.A. Neue Cyclohexylaminderivate mit Aktivitäten von Beta2-adrenergem Agonisten und M3-Muskarin-Antagonisten
EP2592077A1 (de) 2011-11-11 2013-05-15 Almirall, S.A. Neue Cyclohexylaminderivate mit Aktivitäten von Beta2-adrenergem Agonisten und M3-Muskarin-Antagonisten
EP2790619A1 (de) 2011-12-12 2014-10-22 Corinthian Ophthalmic, Inc. Auswurfmechanismus, auswurfvorrichtung und verwendungsverfahren
US8816305B2 (en) * 2011-12-20 2014-08-26 Asml Netherlands B.V. Filter for material supply apparatus
US8771799B2 (en) 2011-12-27 2014-07-08 JM Harwood LLC Liquid delivery system
EP2819669B1 (de) * 2012-02-28 2021-04-21 Boehringer Ingelheim International GmbH Neue treibgashaltige tiotropium-formulierung
EP2641900A1 (de) 2012-03-20 2013-09-25 Almirall, S.A. Neuartige polymorphe Kristallformen von 5-(2-{[6-(2,2-difluor-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxychinolin-2(1H)-on, Heminapadisylat als Agonist des beta2-adrenergen Rezeptors
US9220852B2 (en) 2012-04-10 2015-12-29 Boehringer Ingelheim Microparts Gmbh Method for producing trench-like depressions in the surface of a wafer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
US9562523B2 (en) 2012-10-01 2017-02-07 JM Harwood LLC Wobble drive mechanism
WO2014060431A1 (en) 2012-10-16 2014-04-24 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
EP2738172A1 (de) 2012-11-28 2014-06-04 Almirall, S.A. Neue bizyklische Verbindungen als CRAC-Kanalmodulatoren
US9517315B2 (en) 2012-11-30 2016-12-13 Trudell Medical International Oscillating positive expiratory pressure device
CN102963603A (zh) * 2012-12-08 2013-03-13 胡成佐 一种包装盒
US9518050B2 (en) 2012-12-18 2016-12-13 Almirall, S.A. Cyclohexyl and quinuclidinyl carbamate derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activity
TW201446767A (zh) 2013-02-15 2014-12-16 Almirall Sa 作為磷脂肌醇3-激酶抑製劑之吡咯並三嗪衍生物
JP6454323B2 (ja) 2013-03-15 2019-01-16 パール セラピューティクス，インコーポレイテッド 粒子状結晶性材料のコンディショニングのための方法及びシステム
EP2848615A1 (de) 2013-07-03 2015-03-18 Almirall, S.A. Neue Pyrazolderivate als CRAC-Kanalmodulatoren
EP2835146B1 (de) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Zerstäuber
EP3030298B1 (de) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Vernebler
FI20135903L (fi) * 2013-09-09 2015-03-10 Beneq Oy Laite ja menetelmä aerosolin valmistamiseksi ja kohdistinosa
US10292424B2 (en) * 2013-10-31 2019-05-21 Rai Strategic Holdings, Inc. Aerosol delivery device including a pressure-based aerosol delivery mechanism
DE202014103984U1 (de) * 2014-03-10 2015-06-12 Rpc Bramlage Gmbh Spender
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
PL3139979T3 (pl) 2014-05-07 2023-12-27 Boehringer Ingelheim International Gmbh Jednostka, nebulizator i sposób
EA032459B1 (ru) 2014-05-07 2019-05-31 Бёрингер Ингельхайм Интернациональ Гмбх Небулайзер
GB201408561D0 (en) * 2014-05-14 2014-06-25 The Technology Partnership Plc Aerosolisation engine for liquid drug delivery
US11273271B2 (en) * 2014-07-01 2022-03-15 Aerami Therapeutics, Inc. Aerosolization system with flow restrictor and feedback device
GB201413181D0 (en) 2014-07-25 2014-09-10 Dunne Consultancy Services Ltd Inhaler cartridge system
US10737042B2 (en) 2014-08-26 2020-08-11 Michael Edward Breede Thermal modulation of an inhalable medicament
US10300228B2 (en) 2014-08-26 2019-05-28 Innovosciences, Llc Thermal modulation of an inhalable medicament
US9743999B2 (en) * 2014-08-29 2017-08-29 Piero A. Policicchio Dental prophylaxis device and air appliance
EP3061501A1 (de) 2015-02-27 2016-08-31 Rottapharm Ltd. Zusammensetzung zur behandlung von akne
JP6480598B2 (ja) 2015-04-02 2019-03-13 ヒル−ロム サービシーズ プライヴェート リミテッド 呼吸装置用マニホールド
IL238387B (en) * 2015-04-20 2019-01-31 Paz Ilan Drug dispenser release mechanism
WO2016170009A1 (en) 2015-04-21 2016-10-27 Almirall, S.A. Amino-substituted heterocyclic derivatives as sodium channel inhibitors
WO2016180975A1 (en) * 2015-05-14 2016-11-17 Medical Graphics Italia S.R.L. Kit for performing a bronchial challenge test with methacholine and device containing methacholine
CN108686286A (zh) * 2015-05-16 2018-10-23 苏州汉方医药有限公司 由手动悬浮微颗粒发生器和复方党参组成的药盒
EP3103498B2 (de) * 2015-06-12 2023-06-14 AP Pharma Systems Atomizadores e Dispensadores Ltda Sprühspender für nasale arzneimittel
WO2016202800A1 (en) 2015-06-16 2016-12-22 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
EP3117825A1 (de) 2015-07-16 2017-01-18 Rottapharm S.p.A. Orale formulierung mit berberin und morus-alba-extrakt
EP4134118A3 (de) 2015-07-30 2023-05-03 Trudell Medical International Kombiniertes atemmuskeltraining und oszillierende vorrichtung für positiven ausatmungsdruck
DE102016105998A1 (de) * 2015-09-23 2017-03-23 Rpc Bramlage Gmbh Spender für flüssige bis pastöse Massen
JP7189766B2 (ja) 2015-10-09 2022-12-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング マイクロ構造コンポーネントのコーティング方法
RU2636522C1 (ru) * 2016-06-09 2017-11-23 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Способ и устройство получения мелкодисперсных аэрозолей с предотвращением засорения форсунок
CN106215291A (zh) * 2016-08-17 2016-12-14 岑溪市东正动力科技开发有限公司 一种医用雾化器
CN106390252B (zh) * 2016-08-30 2019-07-30 苏州涵轩信息科技有限公司 一种药液雾化装置
DK3512587T3 (da) 2016-09-15 2022-04-11 Softhale Nv Anordning til administration af et flydende lægemiddel
CN109789107B (zh) * 2016-09-29 2021-12-03 广东东阳光药业有限公司 药物组合物
PT3519024T (pt) * 2016-09-30 2021-06-29 Softhale Nv Nebulizador, em particular inalador, para a nebulização de uma substância ativa líquida para um aerossol, bem como um processo correspondente
DK3615111T3 (da) 2017-04-28 2023-06-06 Softhale Nv Inhalationsanordning
JP7227163B2 (ja) 2017-06-10 2023-02-21 アイノビア，インコーポレイティド 流体を取扱い、目に流体を送出するための方法および装置
WO2018234527A1 (en) 2017-06-22 2018-12-27 Softhale Nv PIRFENIDONE AEROSOL ADMINISTRATION
CN110869134B (zh) * 2017-06-22 2023-12-22 索芙特海尔公司 用于吡非尼酮气雾剂的吸入装置、储存器以及递送方法
WO2018234524A1 (en) 2017-06-22 2018-12-27 Softhale Nv MULTILIQUID NOZZLE
WO2018234525A1 (en) 2017-06-22 2018-12-27 Softhale Nv MULTI-LIQUID NOZZLE INHALATION DEVICE AND METHOD
DK179667B1 (en) 2017-06-30 2019-03-14 Mbh-International A/S An enema device and a method of refilling said device with an enema
TW201919682A (zh) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Ｎｒｆ２路徑的新穎化合物
DE202017005165U1 (de) * 2017-10-06 2017-10-18 WERRTA GmbH Düsen- und Zerstäubungstechnik Düsenkörper
CN111225746B (zh) 2017-10-18 2023-04-04 索芙特海尔公司 用于吸入装置的密封件
US10617832B2 (en) 2017-11-22 2020-04-14 Southwest Research Institute High precision, low dose atomizer
US20210008298A1 (en) 2017-11-27 2021-01-14 Softhale Nv Nozzle fixture for an inhalation device
CN109894907A (zh) * 2017-12-07 2019-06-18 上海铼钠克数控科技股份有限公司 制动装置
EP3501582B1 (de) * 2017-12-21 2022-04-27 Boehringer Ingelheim International GmbH Zerstäuber und kartusche
CN111491682B (zh) * 2017-12-22 2024-02-13 索芙特海尔公司 柔性泵室
ES2936473T3 (es) 2017-12-22 2023-03-17 Softhale Nv Dispositivo de bloqueo
JP7358374B2 (ja) 2018-03-21 2023-10-10 ソフトハレ エヌヴイ 吸入装置用スプレーノズル
CN110388467B (zh) * 2018-04-20 2024-06-07 梅特勒-托利多(常州)测量技术有限公司 吸液手柄控制阀门
EP3563894B1 (de) * 2018-05-04 2021-12-22 Boehringer Ingelheim International GmbH Zerstäuber und behälter
EP3801925A1 (de) 2018-05-30 2021-04-14 Softhale NV Inhalationsvorrichtung mit einer pumpeinheit
CN108499769B (zh) * 2018-06-12 2023-05-19 湖南科道尔生物科技有限公司 一种具有延时自动喷液的高雾化装置
CN108704779A (zh) * 2018-06-20 2018-10-26 浙江普莱得电器有限公司 一种喷枪
GB201810546D0 (en) * 2018-06-27 2018-08-15 Ttp Plc Droplet Dispenser
US20210252234A1 (en) 2018-07-16 2021-08-19 Softhale Nv Improved inhalation device
BR112021001981A2 (pt) * 2018-08-10 2021-04-27 Softhale Nv dispositivo de inalação de alta pressão
EP3628355A1 (de) * 2018-09-27 2020-04-01 Ttp Plc. Kartusche für ein aerosolabgabesystem
CN111345948A (zh) * 2018-09-30 2020-06-30 潘爱平 一种能够呼吸给药的轮椅
WO2020094761A1 (en) 2018-11-09 2020-05-14 Softhale Nv Reservoir for an inhalation device
WO2020141024A1 (de) * 2019-01-03 2020-07-09 Aptar Radolfzell Gmbh Düseneinheit, flüssigkeitsspender mit einer solchen düseneinheit und verfahren zur herstellung solcher düseneinheiten
CN111450361B (zh) * 2019-01-21 2022-02-08 樊启民 一种肺心病雾化呼吸治疗装置
TW202100194A (zh) 2019-04-15 2021-01-01 比利時商索芙特海爾公司 改進的閥
EP3956002A4 (de) * 2019-04-18 2023-01-25 Jon Greenfield Positivdruckinhalator zur abgabe von inhalierbaren medikamenten und verfahren zur verwendung
FR3095968B1 (fr) 2019-05-14 2021-10-01 Aptar France Sas Dispositif de distribution de produit fluide
CN110141744B (zh) * 2019-06-30 2021-03-23 河南省斯科赛斯科技发展有限公司 气流雾化器
CN110627149B (zh) * 2019-08-23 2021-12-07 江苏星鑫分离设备制造有限公司 一种可处理尾气的垃圾渗滤液回喷处理设备
CN110786345A (zh) * 2019-11-13 2020-02-14 申璐璐 一种天然植物抗菌剂
US20210283145A1 (en) 2020-03-13 2021-09-16 Softhale Nv Method for the treatment of viral infections
EP4121032A1 (de) 2020-03-19 2023-01-25 Softhale NV Verfahren zur behandlung von nlrp3-assoziierten erkrankungen
CN111299007B (zh) * 2020-03-20 2021-06-25 浙江宝龙工贸有限公司 一种用于木门生产的喷涂均匀的喷漆装置
TW202206132A (zh) 2020-03-31 2022-02-16 比利時商索芙特海爾公司 吸入設備系統
TW202203997A (zh) 2020-03-31 2022-02-01 比利時商索芙特海爾公司 至少兩種液體組合物的氣霧劑遞送
CN111544715B (zh) * 2020-04-02 2022-08-19 佛山市澳斯卡医疗器械有限公司 一种瓶装雾化器
US20210308047A1 (en) 2020-04-03 2021-10-07 Softhale Nv Methods of treatment using niclosamide
US20230145555A1 (en) 2020-04-10 2023-05-11 Galenus G.H. Ag Composition comprising resveratrol
CN111532591A (zh) * 2020-04-29 2020-08-14 丁亚宁 一种呼吸内科用的消毒喷雾瓶及其使用方法
EP4153346A1 (de) * 2020-05-20 2023-03-29 Victaulic Company Strahler und system zum ableiten eines dekontaminierenden flüssigkeits-gasstroms
US11013688B1 (en) 2020-05-28 2021-05-25 Softhale Nv Methods of treatment of viral diseases
RU2745231C9 (ru) * 2020-06-08 2021-04-27 Акционерное общество "Столетика" Спрей-ингалятор с функцией приготовления и хранения лекарственных форм
WO2021260179A1 (en) 2020-06-26 2021-12-30 Softhale Nv Inverted nozzle fixture and method
CN113171895B (zh) * 2021-04-20 2022-12-13 广州腾龙健康实业股份有限公司 一种多向喷嘴
EP4109066A1 (de) 2021-06-25 2022-12-28 Harro Höfliger Verpackungsmaschinen GmbH Vorrichtung zum prüfen der dichtigkeit einer pumpenbaugruppe für hochdrucksprühapplikatoren
WO2023001750A1 (en) 2021-07-20 2023-01-26 Softhale Nv Inhalation device system with a counting and blocking assembly
DE202021002812U1 (de) 2021-08-31 2021-09-15 Harro Höfliger Verpackungsmaschinen GmbH Vorrichtung zum Prüfen von an Kapillaren befestigten Hochdruckrückschlagventilen, insbesondere für den Einsatz in Sprühapplikatoren
CN114392454B (zh) * 2022-02-09 2024-07-02 商丘市中心医院 一种临床麻醉用局部麻醉可控喷雾装置
WO2024023231A1 (en) 2022-07-29 2024-02-01 Softhale Nv Microfluidic devices and methods of producing
CN115068755B (zh) * 2022-08-24 2023-06-06 中国人民解放军总医院第六医学中心 一种呼吸科用雾化装置
WO2024126359A1 (en) 2022-12-12 2024-06-20 Invox Belgium Nv Microstructured nozzle
CN118079152B (zh) * 2024-04-24 2024-06-21 北安市第一人民医院 一种呼吸内科用药物吸入装置

Family Cites Families (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US334110A (en) * 1886-01-12 Edwaed j
US460458A (en) * 1891-09-29 Edward t
US1035261A (en) * 1912-02-16 1912-08-13 Hermann Strumpf Atomizer.
US1116536A (en) * 1913-10-06 1914-11-10 Charles Ballreich Lawn-sprinkler.
US1276245A (en) * 1916-11-03 1918-08-20 Gilmour Sharp Spraying-nozzle.
US1838873A (en) * 1930-02-27 1931-12-29 Lewis L Scott Atomizer
GB405458A (en) * 1933-05-18 1934-02-08 Harry Krantz An improved device for disinfecting the mouthpieces of telephones
US2024339A (en) * 1933-11-11 1935-12-17 James W Connell Water spraying device
US2052869A (en) * 1934-10-08 1936-09-01 Coanda Henri Device for deflecting a stream of elastic fluid projected into an elastic fluid
US2187779A (en) * 1936-07-22 1940-01-23 Gardner Mfg Company Atomizing nozzle
US2432791A (en) * 1945-12-12 1947-12-16 Osses Jacob Defense weapon
US2673123A (en) * 1949-10-14 1954-03-23 Atlantic Plastics Inc Spray cap
US2676845A (en) * 1949-11-04 1954-04-27 Gen Closure Corp Atomizing closure device for liquid receptacles
US2786656A (en) * 1954-06-23 1957-03-26 Ernest R Corneil Impact spraying of slurries
FR1072399A (fr) * 1961-01-07 1954-09-13 Injecteur intra-dermique
NL296493A (de) * 1962-08-14
US3187748A (en) * 1963-04-29 1965-06-08 Merck And Company Inc Inhalation-actuated aerosol device
US3330277A (en) * 1964-08-17 1967-07-11 Scherer Corp R P Multidose hypodermic injector
US3317002A (en) * 1965-02-08 1967-05-02 Walker Mfg Co Fluid distributing system
GB1131918A (en) * 1965-05-06 1968-10-30 Murray Budd Burgess Jet injector
DE1475174A1 (de) * 1965-09-20 1969-01-16 Afa Corp Fluessigkeitssprayvorrichtung
US3421662A (en) * 1967-03-07 1969-01-14 Ralph W Hanson Dispersal device
US3396874A (en) * 1967-05-15 1968-08-13 Afa Corp Positive action dispensing valve
DE1803541A1 (de) * 1968-10-17 1970-04-23 Wild Dr Walter J Verfahren und Vorrichtung zum Verspruehen von leichtfluessigen Medien
GB1239855A (en) * 1969-01-30 1971-07-21 Pye Ltd Improvements in or relating to liquid injectors for medical respirators
US3514017A (en) * 1969-03-03 1970-05-26 Afa Corp Pressure regulating structure for piston pump
US3575322A (en) * 1969-03-21 1971-04-20 Union Carbide Corp Metering aerosol actuator with downstroke discharge
US3605738A (en) * 1969-06-20 1971-09-20 Paul J Ciranna Medicinal spray device
US3647143A (en) * 1970-04-06 1972-03-07 Champion Spark Plug Co Atomizer
US3838686A (en) * 1971-10-14 1974-10-01 G Szekely Aerosol apparatus for inhalation therapy
BE795375A (fr) * 1972-02-14 1973-08-13 Thiokol Chemical Corp Atomiseur
US3797748A (en) 1972-03-30 1974-03-19 T Nozawa Liquid spraying device
US3818908A (en) * 1972-08-07 1974-06-25 Riker Laboratories Inc Medicament dispenser
US3794247A (en) * 1972-11-22 1974-02-26 Corsette Douglas Frank Spray fitment for squeeze bottles
US3933279A (en) * 1972-11-28 1976-01-20 Ciba-Geigy Corporation Aerosol dispenser for fluid products comprising a piston pump assembly for generating compressed air
US3831861A (en) * 1973-03-23 1974-08-27 Par Way Mfg Co Liquid spray head for producing rectangular spray patterns
US3923202A (en) * 1973-11-29 1975-12-02 Ciba Geigy Corp Non-spitting liquid dispensing device with pressurized product supply
US3878973A (en) * 1973-10-31 1975-04-22 Ciba Geigy Corp Metered dose dispenser
CH588896A5 (de) * 1973-10-31 1977-06-15 Ciba Geigy Ag
US3921857A (en) * 1973-11-29 1975-11-25 Ciba Geigy Corp Non-spitting liquid dispensing device
AT343788B (de) * 1973-11-30 1978-06-12 Thomae Gmbh Dr K Hemmvorrichtung fur pumpdosierventile
US4017007A (en) * 1973-12-26 1977-04-12 Ciba-Geigy Corporation Single dose air pressure operated dispenser
CA1008825A (en) * 1974-03-28 1977-04-19 William E. Warren Pump assembly for an atomizing piston pump
US3893628A (en) * 1974-04-08 1975-07-08 Alsons Corp Spray head
JPS5824183B2 (ja) * 1974-05-17 1983-05-19 コンドウ ヒロシ チクアツフンムソウチ
US3921916A (en) * 1974-12-31 1975-11-25 Ibm Nozzles formed in monocrystalline silicon
US4007855A (en) * 1975-03-24 1977-02-15 Joseph M. Magrath Liquid dispenser of the metering type
CA1099674A (en) 1975-12-05 1981-04-21 Gerald A. Rooney Manually operated liquid dispensing device
IT1069354B (it) * 1976-03-05 1985-03-25 Zanasi Nigris Spa Perfezionamenti nei dosatori volume trici
US4167941A (en) * 1976-10-05 1979-09-18 James D. Pauls, Ltd. (Limited Partnership) Mechanically operated dispensing device for increasing discharge pressure and dispensing time
US4174055A (en) * 1977-04-20 1979-11-13 James D. Pauls & J. Claybrook Lewis & Associates, Ltd. Non-aerosol pressure dispenser
US4179070A (en) * 1977-05-09 1979-12-18 Tetsuya Tada Sprayer
US4174056A (en) * 1977-05-10 1979-11-13 Ciba-Geigy Corporation Pump type dispenser with continuous flow feature
US4079865A (en) * 1977-06-30 1978-03-21 John H. Oltman Non-pulsating, non-throttling, vented pumping system for continuously dispensing product
US4183449A (en) 1978-01-09 1980-01-15 The Afa Corporation Manually operated miniature atomizer
US4245788A (en) * 1978-03-20 1981-01-20 Wright Hershel E Dispensing device for fluid material
US4271875A (en) * 1978-09-21 1981-06-09 Philip Meshberg Dispenser adapted for fast pressure filling
DE2854841C2 (de) * 1978-12-19 1981-03-26 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Flüssigkeitszerstäuber, vorzugsweise Inhalationsgerät
US4345718A (en) * 1979-04-23 1982-08-24 William Horvath Manually actuated trigger sprayer
CA1156695A (en) * 1979-10-10 1983-11-08 Macmillan Bloedel Limited Self protecting spray nozzle
US4602726A (en) * 1979-12-31 1986-07-29 George Goda Dispensing device
US4402432A (en) * 1980-02-13 1983-09-06 Corsette Douglas Frank Leak-proof dispensing pump
DE3007512C2 (de) 1980-02-28 1982-04-29 Fa. Hermann Heye, 3063 Obernkirchen Vorrichtung zum Aufbringen einer Schmier- oder Trennflüssigkeit auf ein Glasformmaschinenteil
DE3166709D1 (en) * 1980-08-04 1984-11-22 Fisons Plc Inhalation device for administering medicaments
GB2109690B (en) * 1981-02-12 1985-02-20 Robert Charles Turner Dose metering plunger devices for use with syringes
US4412632A (en) * 1981-05-28 1983-11-01 Berger Richard F Self-cleaning valve
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
SU992070A1 (ru) * 1981-09-28 1983-01-30 Тартуский Ордена Трудового Красного Знамени Государственный Университет Ингал тор
US4441634A (en) * 1982-01-13 1984-04-10 Philip Meshberg Dispenser adapted for fast pressure filling
FR2521036A1 (fr) * 1982-02-05 1983-08-12 Valois Sa Dispositif de projection de doses precises d'aerosol
FR2524348A1 (fr) * 1982-03-30 1983-10-07 Ramis Michel Vaporisateur pompe
EP0105964A1 (de) * 1982-10-18 1984-04-25 Fischer, Jürgen L. Verfahren zum kontinuierlichen Abtrennen von Schadstoffen aus einem Trägerfluid
US4771769A (en) * 1982-12-20 1988-09-20 Schering Corporation Hand held metered spray dispenser
DE3303419A1 (de) * 1983-02-02 1984-08-02 W. Schlafhorst & Co, 4050 Mönchengladbach Verfahren und vorrichtung zum dosieren und einspritzen kleiner fluessigkeitsmengen in die spleissluft einer druckgas-fadenspleissvorrichtung
JPS59222251A (ja) * 1983-05-31 1984-12-13 Matsushita Electric Works Ltd 電動式粘稠剤押出機
DE3339180C2 (de) 1983-10-28 1993-10-14 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
US4648393A (en) * 1984-11-02 1987-03-10 Ackrad Laboratories, Inc. Breath activated medication spray
DE8621135U1 (de) * 1985-09-02 1987-01-29 Callahan, George Edgar, Prof., 40479 Düsseldorf Sprühvorrichtung zum Aufsetzen auf einen zusammenpressbaren Behälter
US4705034A (en) * 1985-10-02 1987-11-10 Perkins Warren E Method and means for dispensing respirating gases by effecting a known displacement
CA1323004C (en) * 1985-10-15 1993-10-12 Yuji Higo Process for injecting a minute volume of a solution and an apparatus therefor
US4693675A (en) 1986-01-16 1987-09-15 The Pharmasol Corporation Non-throttling discharge pump
US4738398A (en) * 1986-07-29 1988-04-19 Corsette Douglas Frank Sprayer having induced air assist
US4819834A (en) * 1986-09-09 1989-04-11 Minnesota Mining And Manufacturing Company Apparatus and methods for delivering a predetermined amount of a pressurized fluid
GB8629982D0 (en) * 1986-12-16 1987-01-28 English Glass Co Ltd Dispenser pump
WO1988004638A1 (en) * 1986-12-17 1988-06-30 Microvol Limited Pressurised metering dispenser
DE3704210A1 (de) * 1987-02-11 1988-08-25 Friedhelm Schneider Dosierpistole fuer fluessigkeiten und pasten
JPS63232866A (ja) * 1987-03-20 1988-09-28 Tokyo Electron Ltd スプレイノズル
US4896832A (en) * 1987-09-07 1990-01-30 Bespak Plc Dispensing apparatus for metered quantities of pressurised fluid
US4892232A (en) * 1988-07-25 1990-01-09 Martin James H Unit dose dispenser
US4828184A (en) * 1988-08-12 1989-05-09 Ford Motor Company Silicon micromachined compound nozzle
FR2641202B1 (fr) * 1989-01-03 1991-03-15 Poizot Francis Dispositif de production de mousse
ATE91091T1 (de) * 1989-05-31 1993-07-15 Conceptair Anstalt Verfahren und elektrische, elektronische und mechanische vorrichtung zum verteilen, dosieren oder diffundieren, von fluessigen oder gasfoermigen aromen, arzneien und anderen fluessigen oder viskoesen produkten.
US5031839A (en) * 1989-09-13 1991-07-16 Dowelanco Volume controllable applicator
US5056511A (en) * 1989-12-14 1991-10-15 Juergen L. Fischer Method and apparatus for compressing, atomizing, and spraying liquid substances
GB2243880B (en) * 1990-05-01 1994-03-16 Bespak Plc Dispensing device
US5088649A (en) * 1990-07-12 1992-02-18 Par-Way Group Pump sprayable dispensing system for vegetable oil based pan coatings

Also Published As

Publication number Publication date
UA27777C2 (uk) 2000-10-16
GB9215398D0 (en) 1992-09-16
HU9202985D0 (en) 1992-12-28
CZ283820B6 (cs) 1998-06-17
FI924216A0 (fi) 1992-09-21
IE910929A1 (en) 1991-09-25
CN1199009A (zh) 1998-11-18
AU7548491A (en) 1991-10-21
IL97619A (en) 1995-05-26
GR3026065T3 (en) 1998-05-29
PH30833A (en) 1997-11-03
SI9110500A (en) 1996-02-29
DE69128419D1 (de) 1998-01-22
HRP921357A2 (en) 1995-10-31
PT97098A (pt) 1993-04-30
CN1042203C (zh) 1999-02-24
YU50091A (sh) 1994-11-15
CA2078683C (en) 1997-10-07
FI104311B (fi) 1999-12-31
TW253846B (de) 1995-08-11
MY110310A (en) 1998-04-30
AU650870B2 (en) 1994-07-07
YU52998A (sh) 2001-07-10
GB2256805B (en) 1994-04-06
NO923647L (no) 1992-11-09
ATE189413T1 (de) 2000-02-15
CN1119182C (zh) 2003-08-27
ES2141786T3 (es) 2000-04-01
ES2109943T3 (es) 1998-02-01
US5497944A (en) 1996-03-12
DE69131966T2 (de) 2000-07-20
IE62626B1 (en) 1995-02-22
CA2206753A1 (en) 1991-09-22
FI924216A (fi) 1992-09-21
KR0139652B1 (en) 1998-07-01
ATE160947T1 (de) 1997-12-15
NO923647D0 (no) 1992-09-18
RU2104048C1 (ru) 1998-02-10
SI9110500B (sl) 2000-12-31
HK1005059A1 (en) 1998-12-18
JP2630347B2 (ja) 1997-07-16
DE69128419T2 (de) 1998-04-16
DK0521061T3 (da) 1998-03-30
HU216121B (hu) 1999-04-28
CA2078683A1 (en) 1991-09-22
DK0627230T3 (da) 2000-06-26
CN1061362A (zh) 1992-05-27
US5662271A (en) 1997-09-02
BR9106249A (pt) 1993-11-09
EP0521061B1 (de) 1997-12-10
PT97098B (pt) 1998-02-27
SG45171A1 (en) 1998-01-16
WO1991014468A1 (en) 1991-10-03
CA2206753C (en) 2006-10-17
EP0627230B1 (de) 2000-02-02
SK280225B6 (sk) 1999-10-08
GR3033317T3 (en) 2000-09-29
EP0521061A1 (de) 1993-01-07
EP0627230A2 (de) 1994-12-07
IN177383B (de) 1997-01-11
JPH05509241A (ja) 1993-12-22
IL97619A0 (en) 1992-06-21
GB2256805A (en) 1992-12-23
EP0627230A3 (de) 1995-03-01
RS49548B (sr) 2007-02-05
HRP921357B1 (en) 2000-12-31
HUT66175A (en) 1994-09-28
PL165926B1 (pl) 1995-03-31
NO303206B1 (no) 1998-06-15
DE69131966D1 (de) 2000-03-09
YU48710B (sh) 1999-07-28
NZ237502A (en) 1994-02-25

Similar Documents

Publication Publication Date Title
FI104311B1 (fi) Annosinhalointilaite ja -menetelmä
LV10059B (en) An inhaling device
RU93004853A (ru) Ингаляторное устройство
JP2007522902A (ja) ネブライザ
CA2069753A1 (en) Inhalation device
JPH05317427A (ja) 吸入方法と装置
MXPA97001196A (en) Inhaler apparatus with optimizac camera
GEP19991782B (en) inhalation Device for Inhaling Active Powder or Liquid Agent

Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: BOEHRINGER INGELHEIM INTERNATIONAL GMBH