ES2318853T3 - Bloqueo de la subregulacion de linfocitos t asociado a la señalizacion por ctla-4. - Google Patents
Bloqueo de la subregulacion de linfocitos t asociado a la señalizacion por ctla-4. Download PDFInfo
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- ES2318853T3 ES2318853T3 ES96942901T ES96942901T ES2318853T3 ES 2318853 T3 ES2318853 T3 ES 2318853T3 ES 96942901 T ES96942901 T ES 96942901T ES 96942901 T ES96942901 T ES 96942901T ES 2318853 T3 ES2318853 T3 ES 2318853T3
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Landscapes
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/566,853 US5855887A (en) | 1995-07-25 | 1995-12-04 | Blockade of lymphocyte down-regulation associated with CTLA-4 signaling |
| US566853 | 1995-12-04 | ||
| US08/646,605 US5811097A (en) | 1995-07-25 | 1996-05-08 | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| US646605 | 1996-05-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2318853T3 true ES2318853T3 (es) | 2009-05-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10180032.4T Expired - Lifetime ES2579277T3 (es) | 1995-12-04 | 1996-12-04 | Utilización combinada de un agente de bloqueo CTLA-4 y una terapia linfotóxica en el tratamiento de tumores |
| ES96942901T Expired - Lifetime ES2318853T3 (es) | 1995-12-04 | 1996-12-04 | Bloqueo de la subregulacion de linfocitos t asociado a la señalizacion por ctla-4. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10180032.4T Expired - Lifetime ES2579277T3 (es) | 1995-12-04 | 1996-12-04 | Utilización combinada de un agente de bloqueo CTLA-4 y una terapia linfotóxica en el tratamiento de tumores |
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| Country | Link |
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| US (1) | US5811097A (enExample) |
| EP (3) | EP2332561B1 (enExample) |
| JP (2) | JP4477701B2 (enExample) |
| AT (1) | ATE415172T1 (enExample) |
| AU (1) | AU730500B2 (enExample) |
| CA (2) | CA2239448C (enExample) |
| DE (2) | DE69637762D1 (enExample) |
| DK (2) | DK2332561T3 (enExample) |
| ES (2) | ES2579277T3 (enExample) |
| LU (1) | LU91927I2 (enExample) |
| PT (2) | PT865293E (enExample) |
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Families Citing this family (513)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7820798B2 (en) * | 1994-11-07 | 2010-10-26 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| US7597886B2 (en) * | 1994-11-07 | 2009-10-06 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| US7429646B1 (en) | 1995-06-05 | 2008-09-30 | Human Genome Sciences, Inc. | Antibodies to human tumor necrosis factor receptor-like 2 |
| US6051227A (en) * | 1995-07-25 | 2000-04-18 | The Regents Of The University Of California, Office Of Technology Transfer | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| US7964190B2 (en) * | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
| US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
| US20060034844A1 (en) * | 1996-12-04 | 2006-02-16 | The Regents Of The University Of California | Stimulation of T cells against self antigens using CTLA-4 blocking agents |
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| US556763A (en) * | 1896-03-24 | Telephone-switch | ||
| US6090914A (en) * | 1991-06-27 | 2000-07-18 | Bristol-Myers Squibb Company | CTLA4/CD28Ig hybrid fusion proteins and uses thereof |
| KR100238712B1 (ko) * | 1991-06-27 | 2000-01-15 | 스티븐 비. 데이비스 | 씨티엘에이4 수용체,그를 함유한 연합단백질 및 그의 용도 |
| US5770197A (en) * | 1991-06-27 | 1998-06-23 | Bristol-Myers Squibb Company | Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules |
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| JPH08506247A (ja) * | 1993-07-09 | 1996-07-09 | アムジェン ボールダー インコーポレイテッド | 組換えｃｔｌａ４ポリペプチドおよびその製造方法 |
| CA2167091A1 (en) * | 1993-07-26 | 1995-02-02 | Gordon J. Freeman | B7-2: ctl a4/cd 28 counter receptor |
| WO1995005464A1 (en) * | 1993-08-16 | 1995-02-23 | Arch Development Corporation | B7-2: ctla4/cd28 counter receptor |
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| AU4158396A (en) * | 1994-11-10 | 1996-06-06 | Dana-Farber Cancer Institute | Methods for inhibiting graft versus host disease in bone marrow transplantation |
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- 1996-12-04 ES ES10180032.4T patent/ES2579277T3/es not_active Expired - Lifetime
- 1996-12-04 CA CA2239448A patent/CA2239448C/en not_active Expired - Lifetime
- 1996-12-04 ES ES96942901T patent/ES2318853T3/es not_active Expired - Lifetime
- 1996-12-04 JP JP52142597A patent/JP4477701B2/ja not_active Expired - Lifetime
- 1996-12-04 DK DK10180032.4T patent/DK2332561T3/en active
- 1996-12-04 CA CA2770851A patent/CA2770851C/en not_active Expired - Lifetime
- 1996-12-04 PT PT96942901T patent/PT865293E/pt unknown
- 1996-12-04 DE DE69637762T patent/DE69637762D1/de not_active Expired - Fee Related
- 1996-12-04 EP EP10180032.4A patent/EP2332561B1/en not_active Expired - Lifetime
- 1996-12-04 PT PT101800324T patent/PT2332561E/pt unknown
- 1996-12-04 EP EP96942901A patent/EP0865293B1/en not_active Revoked
- 1996-12-04 DK DK96942901T patent/DK0865293T3/da active
- 1996-12-04 WO PCT/US1996/019375 patent/WO1997020574A1/en not_active Ceased
- 1996-12-04 AU AU11473/97A patent/AU730500B2/en not_active Expired
- 1996-12-04 AT AT96942901T patent/ATE415172T1/de active
- 1996-12-04 EP EP08020208.8A patent/EP2106800B1/en not_active Expired - Lifetime
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2008
- 2008-11-13 JP JP2008291542A patent/JP2009114191A/ja not_active Withdrawn
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2012
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- 2012-01-09 LU LU91927C patent/LU91927I2/fr unknown
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| AU730500B2 (en) | 2001-03-08 |
| WO1997020574A1 (en) | 1997-06-12 |
| PT865293E (pt) | 2009-03-06 |
| LU91927I2 (fr) | 2012-03-09 |
| CA2239448C (en) | 2013-10-01 |
| ES2579277T3 (es) | 2016-08-09 |
| CA2770851A1 (en) | 1997-06-12 |
| US5811097A (en) | 1998-09-22 |
| JP2000502331A (ja) | 2000-02-29 |
| EP0865293A1 (en) | 1998-09-23 |
| EP0865293A4 (en) | 2002-02-06 |
| EP2332561A1 (en) | 2011-06-15 |
| EP0865293B1 (en) | 2008-11-26 |
| JP4477701B2 (ja) | 2010-06-09 |
| EP2332561B1 (en) | 2016-03-30 |
| EP2106800A1 (en) | 2009-10-07 |
| DK0865293T3 (da) | 2009-03-23 |
| PT2332561E (pt) | 2016-06-14 |
| CA2770851C (en) | 2013-09-24 |
| DE122012000002I1 (de) | 2012-06-14 |
| EP2106800B1 (en) | 2016-12-07 |
| DE69637762D1 (de) | 2009-01-08 |
| DK2332561T3 (en) | 2016-06-06 |
| JP2009114191A (ja) | 2009-05-28 |
| ATE415172T1 (de) | 2008-12-15 |
| CA2239448A1 (en) | 1997-06-12 |
| AU1147397A (en) | 1997-06-27 |
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