EA201690081A1 - Синтезированные de novo библиотеки генов - Google Patents

Синтезированные de novo библиотеки генов

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Publication number
EA201690081A1
EA201690081A1 EA201690081A EA201690081A EA201690081A1 EA 201690081 A1 EA201690081 A1 EA 201690081A1 EA 201690081 A EA201690081 A EA 201690081A EA 201690081 A EA201690081 A EA 201690081A EA 201690081 A1 EA201690081 A1 EA 201690081A1
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EA
Eurasian Patent Office
Prior art keywords
synthesized
nucleic acids
large libraries
quality
manufacture
Prior art date
Application number
EA201690081A
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English (en)
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EA034459B1 (ru
Inventor
Уильям Баниайи
Билл Джеймс Пек
Андрес Фернандез
Сыюань Чэнь
Пьер Индермуле
Original Assignee
Твист Байосайенс Корпорейшн
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52428204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201690081(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Твист Байосайенс Корпорейшн filed Critical Твист Байосайенс Корпорейшн
Publication of EA201690081A1 publication Critical patent/EA201690081A1/ru
Publication of EA034459B1 publication Critical patent/EA034459B1/ru

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Abstract

В настоящем документе предлагаются синтезированные de novo большие библиотеки нуклеиновых кислот с низкой частотой ошибок. Кроме того, в настоящем документе описаны устройства для изготовления строительных блоков высокого качества, таких как олигонуклеотиды. Более длинные нуклеиновые кислоты могут быть синтезированы параллельно с использованием микрожидкостных блоков. Кроме того, предложенные здесь способы обеспечивают быстрое конструирование больших библиотек длинных генов высокого качества. Также, в настоящем документе предлагаются устройства для изготовления больших библиотек длинных и высококачественных нуклеиновых кислот.
EA201690081A 2013-08-05 2014-08-05 Синтезированные de novo библиотеки генов EA034459B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361862445P 2013-08-05 2013-08-05
US201361862457P 2013-08-05 2013-08-05
PCT/US2014/049834 WO2015021080A2 (en) 2013-08-05 2014-08-05 De novo synthesized gene libraries

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EA201690081A1 true EA201690081A1 (ru) 2016-10-31
EA034459B1 EA034459B1 (ru) 2020-02-11

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EA201690081A EA034459B1 (ru) 2013-08-05 2014-08-05 Синтезированные de novo библиотеки генов

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US (20) US9409139B2 (ru)
EP (3) EP3030682B1 (ru)
JP (4) JP6656733B2 (ru)
KR (6) KR102207770B1 (ru)
CN (2) CN105637097A (ru)
CA (1) CA2918258A1 (ru)
DK (1) DK3030682T3 (ru)
EA (1) EA034459B1 (ru)
ES (2) ES2815099T3 (ru)
GB (1) GB2533173A (ru)
HK (1) HK1225761A1 (ru)
PL (1) PL3030682T3 (ru)
SG (1) SG11201600853UA (ru)
TW (5) TWI707038B (ru)
WO (1) WO2015021080A2 (ru)

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KR20140024270A (ko) 2010-12-30 2014-02-28 파운데이션 메디신 인코포레이티드 종양 샘플의 다유전자 분석의 최적화
DK3030682T3 (da) 2013-08-05 2020-09-14 Twist Bioscience Corp De novo synthesized gene libraries
WO2015026873A1 (en) 2013-08-19 2015-02-26 Singular Bio, Inc. Assays for single molecule detection and use thereof
CA2961210A1 (en) * 2014-09-15 2016-03-24 Abvitro, Inc. High-throughput nucleotide library sequencing
US10040048B1 (en) 2014-09-25 2018-08-07 Synthego Corporation Automated modular system and method for production of biopolymers
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