SG11201407818PA - High-capacity storage of digital information in dna - Google Patents

High-capacity storage of digital information in dna

Info

Publication number
SG11201407818PA
SG11201407818PA SG11201407818PA SG11201407818PA SG11201407818PA SG 11201407818P A SG11201407818P A SG 11201407818PA SG 11201407818P A SG11201407818P A SG 11201407818PA SG 11201407818P A SG11201407818P A SG 11201407818PA SG 11201407818P A SG11201407818P A SG 11201407818PA
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SG
Singapore
Prior art keywords
lllll
international
dna
information
llll
Prior art date
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SG11201407818PA
Inventor
Nick Goldman
John Birney
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European Molecular Biology Lab Embl
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Application filed by European Molecular Biology Lab Embl filed Critical European Molecular Biology Lab Embl
Publication of SG11201407818PA publication Critical patent/SG11201407818PA/en

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F12/00—Accessing, addressing or allocating within memory systems or architectures
    • G06F12/02—Addressing or allocation; Relocation
    • G06F12/0223—User address space allocation, e.g. contiguous or non contiguous base addressing
    • G06F12/023—Free address space management
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/12—Computing arrangements based on biological models using genetic models
    • G06N3/123—DNA computing
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/02—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using elements whose operation depends upon chemical change
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/40—Encryption of genetic data
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/50—Compression of genetic data
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F2212/00—Indexing scheme relating to accessing, addressing or allocation within memory systems or architectures
    • G06F2212/10—Providing a specific technical effect
    • G06F2212/1032—Reliability improvement, data loss prevention, degraded operation etc

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Mathematical Physics (AREA)
  • Nanotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Bioethics (AREA)
  • Molecular Biology (AREA)
  • Artificial Intelligence (AREA)
  • Computing Systems (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Evolutionary Computation (AREA)
  • Data Mining & Analysis (AREA)
  • Computational Linguistics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Software Systems (AREA)
  • Databases & Information Systems (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Compression, Expansion, Code Conversion, And Decoders (AREA)
  • Detection And Correction Of Errors (AREA)
  • Error Detection And Correction (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau „ (10) International Publication Number (43) International Publication Date ^ ^ WO 2013/178801 A3 5 December 2013 (05.12.2013) WIPO I PCT (51) International Patent Classification: G06F19/22 (2011.01) G06N3/12 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/EP2013/061300 31 May 2013 (31.05.2013) English English (30) Priority Data: 61/654,295 1 June 2012 (01.06.2012) (71) Applicant: EUROPEAN MOLECULAR BIOLOGY LABORATORY [DE/DE]; Meyerhofstr. 1, 69117 Heidel­ berg (DE). (72) Inventors: GOLDMAN, Nick; European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cam­ bridge Cambridgeshire CB10 1SD (GB). BIRNEY, John; European Bioinformatics Institute, Wellcome Trust Gen­ ome Campus, Hinxton, Cambridge Cambridgeshire CB10 1SD(GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Ug (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (74) Agent: 24IP LAW GROUP SONNENBERG FORT- MANN; Patent- und Rechtsanwalte, Dr. Robert Harrison, HerzogspitalstraBe 10a, 80331 Miinchen (DE). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) [Continued on next page] (54) Title: HIGH-CAPACITY STORAGE OF DIGITAL INFORMATION IN DNA binary/text file I --.00011001110011100110011000010111010101011111... I | ^Thoui«^morelovel^_and_jriore_tem£erate ^^__| i . TAGATGTGTACAGACTACGCGCAGCGAGATCGACTCGCAGTGCTGAGTGACAGACTAGTCACGTCGCAGCGCTAG 1 I I alternate fragments have file information alemented T-H o 00 00 l> T-H rn T-H o CJ O ^ d DNA-encoded indexing information added Figure 2 (57) Abstract: A method for storage of an item of information (210) disclosed. The method comprises encoding is bytes (720) in the item of information (210), and representing using a schema the encoded bytes by a DNA nucleotide to produce DNA sequence a (230). The DNA sequence (230) is broken into a plurality of overlapping DNA segments (240) and indexing information (250) ad­ ded to the plurality of DNA segments. Finally, the plurality of DNA segments (240) is synthesized (790) and stored (795). WO 2013/178801 A3 I lllll llllllll II llllll III lllll lllll lllll lllll III III III lllll lllll llll lllll lllllll llll llll llll (88) Date of publication of the international search report: 23 January 2014
SG11201407818PA 2012-06-01 2013-05-31 High-capacity storage of digital information in dna SG11201407818PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261654295P 2012-06-01 2012-06-01
PCT/EP2013/061300 WO2013178801A2 (en) 2012-06-01 2013-05-31 High-capacity storage of digital information in dna

Publications (1)

Publication Number Publication Date
SG11201407818PA true SG11201407818PA (en) 2014-12-30

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SG11201407818PA SG11201407818PA (en) 2012-06-01 2013-05-31 High-capacity storage of digital information in dna

Country Status (15)

Country Link
US (4) US10387301B2 (en)
EP (2) EP3346404A1 (en)
JP (4) JP2015529864A (en)
KR (1) KR20150016572A (en)
CN (2) CN107055468A (en)
AU (5) AU2013269536B2 (en)
CA (1) CA2874540A1 (en)
DK (1) DK2856375T3 (en)
ES (1) ES2698609T3 (en)
HK (2) HK1208937A1 (en)
IL (4) IL235954B (en)
IN (1) IN2014DN09960A (en)
RU (1) RU2014152796A (en)
SG (1) SG11201407818PA (en)
WO (1) WO2013178801A2 (en)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201407818PA (en) * 2012-06-01 2014-12-30 European Molecular Biology Lab Embl High-capacity storage of digital information in dna
EP2875458A2 (en) 2012-07-19 2015-05-27 President and Fellows of Harvard College Methods of storing information using nucleic acids
DK3030682T3 (en) 2013-08-05 2020-09-14 Twist Bioscience Corp DE NOVO SYNTHESIZED GENE LIBRARIES
GB2521387B (en) * 2013-12-18 2020-05-27 Ge Healthcare Uk Ltd Oligonucleotide data storage on solid supports
KR20150092585A (en) * 2014-02-05 2015-08-13 한국전자통신연구원 DNA data compression Method and Apparatus based on binary image
US10027347B2 (en) 2014-03-28 2018-07-17 Thomson Licensing Methods for storing and reading digital data on a set of DNA strands
CN105022935A (en) * 2014-04-22 2015-11-04 中国科学院青岛生物能源与过程研究所 Encoding method and decoding method for performing information storage by means of DNA
EP2958238A1 (en) 2014-06-17 2015-12-23 Thomson Licensing Method and apparatus for encoding information units in code word sequences avoiding reverse complementarity
KR101788673B1 (en) * 2014-06-24 2017-11-15 싸이퍼롬, 인코퍼레이티드 Method for protecting nucleic acid sequence data security and computer readable storage medium storing the method
WO2015199440A1 (en) * 2014-06-24 2015-12-30 서울대학교산학협력단 Nucleic acid sequence security method, device, and recording medium having same saved therein
WO2016069913A1 (en) * 2014-10-29 2016-05-06 Massachusetts Institute Of Technology Dna cloaking technologies
WO2016126987A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Compositions and methods for synthetic gene assembly
WO2016126882A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
CN104850760B (en) * 2015-03-27 2016-12-21 苏州泓迅生物科技有限公司 The information storing and reading method of artificial-synthetic DNA's storage medium
WO2016164779A1 (en) * 2015-04-10 2016-10-13 University Of Washington Integrated system for nucleic acid-based storage of digital data
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
US10423341B1 (en) * 2015-06-12 2019-09-24 Bahram Ghaffarzadeh Kermani Accurate and efficient DNA-based storage of electronic data
US9898579B2 (en) 2015-06-16 2018-02-20 Microsoft Technology Licensing, Llc Relational DNA operations
WO2017011492A1 (en) * 2015-07-13 2017-01-19 President And Fellows Of Harvard College Methods for retrievable information storage using nucleic acids
IL258164B (en) 2015-09-18 2022-09-01 Twist Bioscience Corp Methods for modulating protein and cellular activity and method for nucleic acid synthesis
US11512347B2 (en) 2015-09-22 2022-11-29 Twist Bioscience Corporation Flexible substrates for nucleic acid synthesis
US10566077B1 (en) 2015-11-19 2020-02-18 The Board Of Trustees Of The University Of Illinois Re-writable DNA-based digital storage with random access
EP3173961A1 (en) * 2015-11-27 2017-05-31 Thomson Licensing Method for storing user data and decoding information in synthesized oligos, apparatus and substance
EP3384077A4 (en) 2015-12-01 2019-05-08 Twist Bioscience Corporation Functionalized surfaces and preparation thereof
EP3414694A4 (en) 2016-02-12 2019-10-23 Pegasus Media Security, LLC Security enhanced portable data store and processor for allowing secure and selective access to genomic data
US10438662B2 (en) 2016-02-29 2019-10-08 Iridia, Inc. Methods, compositions, and devices for information storage
US10859562B2 (en) 2016-02-29 2020-12-08 Iridia, Inc. Methods, compositions, and devices for information storage
US10640822B2 (en) 2016-02-29 2020-05-05 Iridia, Inc. Systems and methods for writing, reading, and controlling data stored in a polymer
EP3427385A1 (en) * 2016-03-08 2019-01-16 Thomson Licensing Method and device for decoding data segments derived from oligonucleotides and related sequencer
EP3470997B1 (en) * 2016-05-04 2024-10-23 BGI Shenzhen Method for using dna to store text information, decoding method therefor and application thereof
EP3478852B1 (en) 2016-07-01 2020-08-12 Microsoft Technology Licensing, LLC Storage through iterative dna editing
US11359234B2 (en) 2016-07-01 2022-06-14 Microsoft Technology Licensing, Llc Barcoding sequences for identification of gene expression
US10892034B2 (en) 2016-07-01 2021-01-12 Microsoft Technology Licensing, Llc Use of homology direct repair to record timing of a molecular event
JP6854340B2 (en) 2016-08-22 2021-04-07 ツイスト バイオサイエンス コーポレーション Denovo Synthesized Nucleic Acid Library
US11177019B2 (en) * 2016-08-30 2021-11-16 Tsinghua University Method for biologically storing and restoring data
US10417457B2 (en) 2016-09-21 2019-09-17 Twist Bioscience Corporation Nucleic acid based data storage
US10370246B1 (en) * 2016-10-20 2019-08-06 The Board Of Trustees Of The University Of Illinois Portable and low-error DNA-based data storage
WO2018081566A1 (en) * 2016-10-28 2018-05-03 Integrated Dna Technologies, Inc. Dna data storage using reusable nucleic acids
US10650312B2 (en) 2016-11-16 2020-05-12 Catalog Technologies, Inc. Nucleic acid-based data storage
AU2017363146B2 (en) 2016-11-16 2023-11-02 Catalog Technologies, Inc. Systems for nucleic acid-based data storage
EP3513346B1 (en) * 2016-11-30 2020-04-15 Microsoft Technology Licensing, LLC Dna random access storage system via ligation
US10853244B2 (en) * 2016-12-07 2020-12-01 Sandisk Technologies Llc Randomly writable memory device and method of operating thereof
US10907274B2 (en) 2016-12-16 2021-02-02 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
US10839948B2 (en) 2016-12-29 2020-11-17 Intel Corporation Microfluidic information-encoding polymer data storage
US10793897B2 (en) 2017-02-08 2020-10-06 Microsoft Technology Licensing, Llc Primer and payload design for retrieval of stored polynucleotides
US10787699B2 (en) * 2017-02-08 2020-09-29 Microsoft Technology Licensing, Llc Generating pluralities of primer and payload designs for retrieval of stored nucleotides
US10689684B2 (en) 2017-02-14 2020-06-23 Microsoft Technology Licensing, Llc Modifications to polynucleotides for sequencing
CN106845158A (en) * 2017-02-17 2017-06-13 苏州泓迅生物科技股份有限公司 A kind of method that information Store is carried out using DNA
CN118116478A (en) 2017-02-22 2024-05-31 特韦斯特生物科学公司 Nucleic acid-based data storage
US10930370B2 (en) 2017-03-03 2021-02-23 Microsoft Technology Licensing, Llc Polynucleotide sequencer tuned to artificial polynucleotides
CA3056388A1 (en) 2017-03-15 2018-09-20 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
US10774379B2 (en) 2017-03-15 2020-09-15 Microsoft Technology Licensing, Llc Random access of data encoded by polynucleotides
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
WO2018231872A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
RU2659025C1 (en) * 2017-06-14 2018-06-26 Общество с ограниченной ответственностью "ЛЭНДИГРАД" Methods of encoding and decoding information
US10742233B2 (en) * 2017-07-11 2020-08-11 Erlich Lab Llc Efficient encoding of data for storage in polymers such as DNA
CN109300508B (en) * 2017-07-25 2020-08-11 南京金斯瑞生物科技有限公司 DNA data storage coding decoding method
WO2019040871A1 (en) * 2017-08-24 2019-02-28 Miller Julian Device for information encoding and, storage using artificially expanded alphabets of nucleic acids and other analogous polymers
US11810651B2 (en) 2017-09-01 2023-11-07 Seagate Technology Llc Multi-dimensional mapping of binary data to DNA sequences
US11407837B2 (en) 2017-09-11 2022-08-09 Twist Bioscience Corporation GPCR binding proteins and synthesis thereof
US11538554B1 (en) 2017-09-19 2022-12-27 The Board Of Trustees Of The Univ Of Illinois Nick-based data storage in native nucleic acids
US10810495B2 (en) * 2017-09-20 2020-10-20 University Of Wyoming Methods for data encoding in DNA and genetically modified organism authentication
CA3079613A1 (en) 2017-10-20 2019-04-25 Twist Bioscience Corporation Heated nanowells for polynucleotide synthesis
WO2019081145A1 (en) 2017-10-27 2019-05-02 Eth Zurich Encoding and decoding information in synthetic dna with cryptographic keys generated based on polymorphic features of nucleic acids
WO2019136175A1 (en) 2018-01-04 2019-07-11 Twist Bioscience Corporation Dna-based digital information storage
JP7364604B2 (en) 2018-03-16 2023-10-18 カタログ テクノロジーズ， インコーポレイテッド Chemical methods for nucleic acid-based data storage
WO2019191083A1 (en) * 2018-03-26 2019-10-03 Colorado State University Research Foundation Apparatuses, systems and methods for generating and tracking molecular digital signatures to ensure authenticity and integrity of synthetic dna molecules
KR102138864B1 (en) * 2018-04-11 2020-07-28 경희대학교 산학협력단 Dna digital data storage device and method, and decoding method of dna digital data storage device
CN112313749A (en) 2018-04-13 2021-02-02 香港理工大学 Data storage using peptides
CN108631791B (en) * 2018-05-14 2021-08-10 东南大学 Low-density parity check code decoding method based on chemical reaction network
US20200193301A1 (en) 2018-05-16 2020-06-18 Catalog Technologies, Inc. Compositions and methods for nucleic acid-based data storage
AU2019270243A1 (en) 2018-05-18 2021-01-07 Twist Bioscience Corporation Polynucleotides, reagents, and methods for nucleic acid hybridization
CN110569974B (en) * 2018-06-06 2021-08-24 天津大学 DNA storage layered representation and interweaving coding method capable of containing artificial base
US20210210171A1 (en) 2018-06-07 2021-07-08 Vib Vzw A method of storing information using dna molecules
US11854669B1 (en) 2018-07-30 2023-12-26 National Technology & Engineering Solutions Of Sandia, Llc Synthetic nucleic acids for information storage and transmission
KR102236439B1 (en) * 2018-08-30 2021-04-06 (주) 케일헬스케어 Method for storing digital information into DNA molecule and apparatus therefor
US11515012B1 (en) 2018-09-22 2022-11-29 Mark Gordon Arnold Method and apparatus for a pipelined DNA memory hierarchy
US11017170B2 (en) * 2018-09-27 2021-05-25 At&T Intellectual Property I, L.P. Encoding and storing text using DNA sequences
EP3651156A1 (en) * 2018-11-07 2020-05-13 BioSistemika d.o.o. Nucleic acid-based data storage
EP3904527A4 (en) * 2018-12-26 2022-08-10 BGI Shenzhen Method and device for fixed-point editing of nucleotide sequence stored with data
CN109887549B (en) * 2019-02-22 2023-01-20 天津大学 Data storage and restoration method and device
WO2020176680A1 (en) 2019-02-26 2020-09-03 Twist Bioscience Corporation Variant nucleic acid libraries for antibody optimization
CN113766930A (en) 2019-02-26 2021-12-07 特韦斯特生物科学公司 Variant nucleic acid libraries of GLP1 receptors
EP3966823A1 (en) 2019-05-09 2022-03-16 Catalog Technologies, Inc. Data structures and operations for searching, computing, and indexing in dna-based data storage
GB201907460D0 (en) 2019-05-27 2019-07-10 Vib Vzw A method of storing information in pools of nucleic acid molecules
WO2020243076A1 (en) 2019-05-31 2020-12-03 Illumina, Inc. System and method for storage
WO2020243074A1 (en) 2019-05-31 2020-12-03 Illumina, Inc. Obtaining information from a biological sample in a flow cell
CN112689751A (en) 2019-05-31 2021-04-20 伊鲁米那股份有限公司 Flow cell with one or more barrier features
US11229909B2 (en) 2019-05-31 2022-01-25 Illumina, Inc. Flow cell with selective deposition or activation of nucleotides
EP3977456A4 (en) 2019-05-31 2023-05-31 Illumina Inc Storage device, system, and method
AU2020298294A1 (en) 2019-06-21 2022-02-17 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
US11066661B2 (en) 2019-08-20 2021-07-20 Seagate Technology Llc Methods of gene assembly and their use in DNA data storage
US12091777B2 (en) 2019-09-23 2024-09-17 Twist Bioscience Corporation Variant nucleic acid libraries for CRTH2
CA3157804A1 (en) 2019-10-11 2021-04-15 Catalog Technologies, Inc. Nucleic acid security and authentication
US11755640B2 (en) * 2019-12-20 2023-09-12 The Board Of Trustees Of The University Of Illinois DNA-based image storage and retrieval
US11702689B2 (en) * 2020-04-24 2023-07-18 Microsoft Technology Licensing, Llc Homopolymer primers for amplification of polynucleotides created by enzymatic synthesis
CN111680797B (en) * 2020-05-08 2023-06-06 中国科学院计算技术研究所 DNA type printer, DNA-based data storage device and method
AU2021271639A1 (en) 2020-05-11 2022-12-08 Catalog Technologies, Inc. Programs and functions in DNA-based data storage
PT116392B (en) 2020-05-15 2022-06-30 Univ Aveiro METHOD AND COMPOSITION FOR STABILIZING AND STORING DNA AT ROOM TEMPERATURE AND USES THEREOF
CN111737955A (en) * 2020-06-24 2020-10-02 任兆瑞 Method for storing character dot matrix by using DNA character code
CN111858510B (en) * 2020-07-16 2021-08-20 中国科学院北京基因组研究所(国家生物信息中心) DNA type storage system and method
US11837302B1 (en) 2020-08-07 2023-12-05 Iridia, Inc. Systems and methods for writing and reading data stored in a polymer using nano-channels
KR102418617B1 (en) * 2020-10-13 2022-07-07 서울대학교산학협력단 DNA storage encoding methods, programs and devices that limit base ratio and successive occurrences
US11993769B2 (en) 2021-04-14 2024-05-28 Microsoft Technology Licensing, Llc Compostable silica encapsulation of oligonucleotides for long-term storage
CN113314187B (en) * 2021-05-27 2022-05-10 广州大学 Data storage method, decoding method, system, device and storage medium
US11823066B2 (en) 2021-05-28 2023-11-21 Bank Of America Corporation Enterprise market volatility predictions through synthetic DNA and mutant nucleotides
US11823065B2 (en) 2021-05-28 2023-11-21 Bank Of America Corporation Enterprise market volatility predictions through synthetic DNA and mutant nucleotides
US11823064B2 (en) 2021-05-28 2023-11-21 Bank Of America Corporation Enterprise market volatility prediction through synthetic DNA and mutant nucleotides
CN116451780B (en) * 2022-01-05 2024-07-05 密码子（杭州）科技有限公司 Method and apparatus for storing information in molecules
KR20240056939A (en) 2022-10-24 2024-05-02 (주)디나스텍 Decrambling method for scrambled binary data to original binary data
KR20240049911A (en) 2022-10-11 2024-04-18 (주)디나스텍 Binary data scramble method for preventing repeating placement fo nucleotide sequence
KR20240048218A (en) 2022-10-06 2024-04-15 (주)디나스텍 Dna encoding method and apparatus for low error possibility
KR20240058289A (en) 2022-10-26 2024-05-03 (주)디나스텍 Dna encoding method and apparatus for improving structural stability
KR20240126946A (en) 2023-02-15 2024-08-22 이근우 Dna encoding and decoding method using degenerate nucleotide
KR20240123633A (en) 2023-02-07 2024-08-14 이근우 Dna encoding and decoding method using degenerate nucleotide

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1983052A3 (en) * 1999-03-18 2009-01-07 Complete Genomics AS Methods of cloning and producing fragment chains with readable information content
ATE347617T1 (en) * 1999-05-06 2006-12-15 Sinai School Medicine DNA-BASED STEGANOGRAPHY
GB0103364D0 (en) * 2001-02-10 2001-03-28 Nat Inst Of Agricultural Botan Storage of encoded information within biological macromolecules
US7110885B2 (en) * 2001-03-08 2006-09-19 Dnaprint Genomics, Inc. Efficient methods and apparatus for high-throughput processing of gene sequence data
WO2003025123A2 (en) * 2001-08-28 2003-03-27 Mount Sinai School Of Medecine Dna: a medium for long-term information storage specification
US7158892B2 (en) 2002-06-28 2007-01-02 International Business Machines Corporation Genomic messaging system
US20050053968A1 (en) * 2003-03-31 2005-03-10 Council Of Scientific And Industrial Research Method for storing information in DNA
US6943417B2 (en) * 2003-05-01 2005-09-13 Clemson University DNA-based memory device and method of reading and writing same
TWI326308B (en) * 2003-08-06 2010-06-21 Applied Dna Sciences Inc British Virgin Island Apdn B V I Inc Method for concealing a secret information carried within a dna molecule and method for decoding thereof
JP2005072772A (en) * 2003-08-21 2005-03-17 Sony Ericsson Mobilecommunications Japan Inc Data backup system, terminal, and data backup program
CN101137991A (en) * 2005-02-11 2008-03-05 智明基因有限责任公司 Computer-implemented method and computer-based system for validating DNA sequencing data
US20070067332A1 (en) * 2005-03-14 2007-03-22 Gridiron Software, Inc. Distributed, secure digital file storage and retrieval
US20070113137A1 (en) * 2005-10-22 2007-05-17 Ho Seung Ryu Error Correction in Binary-encoded DNA Using Linear Feedback Shift Registers
WO2007091064A1 (en) * 2006-02-08 2007-08-16 Solexa Limited End modification to prevent over-representation of fragments
KR101829182B1 (en) * 2009-04-02 2018-03-29 플루이다임 코포레이션 Multi-primer amplification method for barcoding of target nucleic acids
WO2011071923A2 (en) * 2009-12-07 2011-06-16 Illumina, Inc. Multi-sample indexing for multiplex genotyping
RU106771U1 (en) 2011-04-14 2011-07-20 Межрегиональное общественное учреждение "Институт инженерной физики" DEVICE FOR STORAGE AND TRANSFER OF DATA WITH CORRECTION OF ERRORS IN THE BYTE OF INFORMATION AND DETECTION OF ERRORS IN THE BYtes OF INFORMATION
WO2012149171A1 (en) * 2011-04-27 2012-11-01 The Regents Of The University Of California Designing padlock probes for targeted genomic sequencing
CN102329884B (en) * 2011-10-20 2013-05-08 东南大学 Synchronous synthesis and DNA sequencing method for two nucleotides and application thereof
SG11201407818PA (en) * 2012-06-01 2014-12-30 European Molecular Biology Lab Embl High-capacity storage of digital information in dna
EP2875458A2 (en) 2012-07-19 2015-05-27 President and Fellows of Harvard College Methods of storing information using nucleic acids
US9255265B2 (en) * 2013-03-15 2016-02-09 Illumina, Inc. Methods for producing stranded cDNA libraries

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