SG11201407669QA - Methods for improving safety of blood-brain barrier transport - Google Patents
Methods for improving safety of blood-brain barrier transportInfo
- Publication number
- SG11201407669QA SG11201407669QA SG11201407669QA SG11201407669QA SG11201407669QA SG 11201407669Q A SG11201407669Q A SG 11201407669QA SG 11201407669Q A SG11201407669Q A SG 11201407669QA SG 11201407669Q A SG11201407669Q A SG 11201407669QA SG 11201407669Q A SG11201407669Q A SG 11201407669QA
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- SG
- Singapore
- Prior art keywords
- lllll
- genentech
- san francisco
- international
- south san
- Prior art date
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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Abstract
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 28 November 2013 (28.11.2013) WIPOIPCT (10) International Publication Number WO 2013/177062 A2 (51) International Patent Classification: C07K16/28 (2006.01) A61K39/395 (2006.01) C07K16/40 (2006.01) A61P 25/00 (2006.01) C07K16/46 (2006.01) A ft IK 47/48 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication (30) Priority Language: Data: 61/649,878 61/698,495 61/763,915 21 May 2012 (21.05.2012) 7 September 2012 (07.09.2012) 12 February 2013 (12.02.2013) PCT/US2013/041860 20 May 2013 (20.05.2013) English English US US us (71) Applicant (for all designated States except AL, AT, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT ; RO, RS, SE, SI, SK, SM, TR): GENENTECH, INC. [US/US]; DNA Way, 1 South San Francisco, Califor nia 94080 (US). (71) Applicant (for AL, AT, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR only): F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH). (72) Inventors: WATTS, Ryan, Jefferson; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). YU ZUCHERO, Joy; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). COUCH, Jessica; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). DENNIS, Mark; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). [Continued on next page] (54) Title: METHODS FOR IMPROVING SAFETY OF BLOOD-BRAIN BARRIER TRANSPORT O O ^ 0 sb \"5 c. 01 o <D ^3 CO jj j C5 60- 40- ZU- Hr Post-close (57) Abstract: The present invention relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport. ~™i— 50 50 —r~ 50 Anti~TfR D Anti-TfR / 0 6 AC El Control igG WO 2013/177062 A2 I lllll llllllll II llllll III lllll lllll III III III lllll llll llll lllll lllll lllll lllll lllllll llll llll (74) Agents: ELLIOTT, Jennifer, L. et al.; Genentech, Inc., 1 DNA Way, Mail Stop 49, South San Francisco, Califor nia 94080 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — without international search report and to be republished upon receipt of that report (Rule 48.2(g)) — with sequence listing part of description (Rule 5.2(a))
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261649878P | 2012-05-21 | 2012-05-21 | |
US201261698495P | 2012-09-07 | 2012-09-07 | |
US201361763915P | 2013-02-12 | 2013-02-12 | |
PCT/US2013/041860 WO2013177062A2 (en) | 2012-05-21 | 2013-05-20 | Methods for improving safety of blood-brain barrier transport |
Publications (1)
Publication Number | Publication Date |
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SG11201407669QA true SG11201407669QA (en) | 2014-12-30 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SG11201407669QA SG11201407669QA (en) | 2012-05-21 | 2013-05-20 | Methods for improving safety of blood-brain barrier transport |
Country Status (20)
Country | Link |
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US (2) | US20150353639A1 (en) |
EP (2) | EP2852618A2 (en) |
JP (2) | JP6419068B2 (en) |
KR (3) | KR102293061B1 (en) |
CN (2) | CN104520325A (en) |
AU (2) | AU2013266611B2 (en) |
BR (1) | BR112014028838A2 (en) |
CA (1) | CA2873929C (en) |
CL (1) | CL2014003161A1 (en) |
CO (1) | CO7151532A2 (en) |
EA (1) | EA201491920A1 (en) |
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