DE69405551T2 - 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen - Google Patents

3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen

Info

Publication number
DE69405551T2
DE69405551T2 DE69405551T DE69405551T DE69405551T2 DE 69405551 T2 DE69405551 T2 DE 69405551T2 DE 69405551 T DE69405551 T DE 69405551T DE 69405551 T DE69405551 T DE 69405551T DE 69405551 T2 DE69405551 T2 DE 69405551T2
Authority
DE
Germany
Prior art keywords
vaccine compositions
monophosphoryl lipid
deacylated monophosphoryl
containing vaccine
deacylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69405551T
Other languages
English (en)
Other versions
DE69405551D1 (de
DE69405551T3 (de
Inventor
Pierre Hauser
Pierre Voet
Moncef Slaoui
Nathalie Marie- Garcon-Johnson
Pierre Desmons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26302633&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69405551(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB939306029A external-priority patent/GB9306029D0/en
Priority claimed from GB9403417A external-priority patent/GB9403417D0/en
Application filed by SmithKline Beecham Biologicals SA filed Critical SmithKline Beecham Biologicals SA
Publication of DE69405551D1 publication Critical patent/DE69405551D1/de
Publication of DE69405551T2 publication Critical patent/DE69405551T2/de
Application granted granted Critical
Publication of DE69405551T3 publication Critical patent/DE69405551T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DE69405551T 1993-03-23 1994-03-14 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen Expired - Lifetime DE69405551T3 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9306029 1993-03-23
GB939306029A GB9306029D0 (en) 1993-03-23 1993-03-23 Vaccine compositions
GB9403417 1994-02-23
GB9403417A GB9403417D0 (en) 1994-02-23 1994-02-23 Vaccine compositions
PCT/EP1994/000818 WO1994021292A1 (en) 1993-03-23 1994-03-14 Vaccine compositions containing 3-o deacylated monophosphoryl lipid a

Publications (3)

Publication Number Publication Date
DE69405551D1 DE69405551D1 (de) 1997-10-16
DE69405551T2 true DE69405551T2 (de) 1998-03-26
DE69405551T3 DE69405551T3 (de) 2005-10-20

Family

ID=26302633

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69405551T Expired - Lifetime DE69405551T3 (de) 1993-03-23 1994-03-14 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen
DE69428136T Expired - Lifetime DE69428136T3 (de) 1993-03-23 1994-03-14 3-0-Deazylierte Monophosphoryl Lipid A enthaltende Impfstoff-Zusammensetzungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69428136T Expired - Lifetime DE69428136T3 (de) 1993-03-23 1994-03-14 3-0-Deazylierte Monophosphoryl Lipid A enthaltende Impfstoff-Zusammensetzungen

Country Status (28)

Country Link
US (1) US5776468A (de)
EP (3) EP0812593B8 (de)
JP (2) JP4028593B2 (de)
KR (1) KR100310510B1 (de)
CN (1) CN1087176C (de)
AP (1) AP515A (de)
AT (2) ATE157882T1 (de)
AU (1) AU685443B2 (de)
BR (1) BR9405957A (de)
CZ (1) CZ289476B6 (de)
DE (2) DE69405551T3 (de)
DK (2) DK0689454T4 (de)
DZ (1) DZ1763A1 (de)
ES (2) ES2109685T5 (de)
FI (1) FI110844B (de)
GR (1) GR3025483T3 (de)
HK (3) HK1011930A1 (de)
HU (1) HU219056B (de)
IL (1) IL109056A (de)
MA (1) MA23143A1 (de)
NO (2) NO322578B1 (de)
NZ (1) NZ263538A (de)
PL (1) PL178578B1 (de)
PT (1) PT812593E (de)
SA (1) SA94140762B1 (de)
SG (1) SG48309A1 (de)
SK (1) SK117395A3 (de)
WO (1) WO1994021292A1 (de)

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DK0812593T4 (da) 2008-05-13
DK0689454T4 (da) 2005-05-30
PL178578B1 (pl) 2000-05-31
CZ246795A3 (en) 1996-03-13
HK1011930A1 (en) 1999-07-23
EP0689454B1 (de) 1997-09-10
DE69405551T3 (de) 2005-10-20

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