PT1096954E - Composicoes de adjuvante e vacina contendo monofosforil-lipido a - Google Patents

Composicoes de adjuvante e vacina contendo monofosforil-lipido a

Info

Publication number
PT1096954E
PT1096954E PT99935566T PT99935566T PT1096954E PT 1096954 E PT1096954 E PT 1096954E PT 99935566 T PT99935566 T PT 99935566T PT 99935566 T PT99935566 T PT 99935566T PT 1096954 E PT1096954 E PT 1096954E
Authority
PT
Portugal
Prior art keywords
adjuvant
lipid
compositions
monophosphalp
vaccine containing
Prior art date
Application number
PT99935566T
Other languages
English (en)
Inventor
Vincent James Laposta
John Hayward Eldridge
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PT1096954E publication Critical patent/PT1096954E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
PT99935566T 1998-07-14 1999-07-13 Composicoes de adjuvante e vacina contendo monofosforil-lipido a PT1096954E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11539298A 1998-07-14 1998-07-14

Publications (1)

Publication Number Publication Date
PT1096954E true PT1096954E (pt) 2004-12-31

Family

ID=22361090

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99935566T PT1096954E (pt) 1998-07-14 1999-07-13 Composicoes de adjuvante e vacina contendo monofosforil-lipido a

Country Status (14)

Country Link
EP (1) EP1096954B1 (pt)
JP (1) JP2002520373A (pt)
KR (1) KR100586804B1 (pt)
CN (1) CN1247262C (pt)
AT (1) ATE278420T1 (pt)
AU (1) AU763770B2 (pt)
BR (1) BR9912067A (pt)
CA (1) CA2333578C (pt)
DE (1) DE69920915T2 (pt)
DK (1) DK1096954T3 (pt)
ES (1) ES2229745T3 (pt)
IL (1) IL140890A0 (pt)
PT (1) PT1096954E (pt)
WO (1) WO2000003744A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
EP1141308B1 (en) 1998-12-22 2007-02-07 Microscience Limited Group b streptococcus proteins, and their use
PL206832B1 (pl) * 2000-05-19 2010-09-30 Corixa Corp Zastosowanie związków opartych na mono- i disacharydach
FR2814956B1 (fr) 2000-10-06 2003-01-24 Seppic Sa Nouvelle composition vaccinale, procede pour sa preparation, utilisation comme composition injectale en medecine humaine ou veterinaire et nouveau procede de conservation
EA014314B1 (ru) * 2005-08-02 2010-10-29 Новартис Вэксинес Энд Дайэгностикс Срл Пониженная интерференция между маслосодержащими адъювантами и антигенами, содержащими поверхностно-активные вещества
AU2012279154A1 (en) * 2011-07-01 2014-02-20 The Regents Of The University Of California Herpes virus vaccine and methods of use
US9241988B2 (en) 2012-04-12 2016-01-26 Avanti Polar Lipids, Inc. Disaccharide synthetic lipid compounds and uses thereof
US20160193326A1 (en) * 2013-09-05 2016-07-07 Immune Design Corp. Vaccine Compositions for Drug Addiction
CN116199727A (zh) * 2021-12-01 2023-06-02 上海安奕康生物科技有限公司 一种mpl三乙胺盐、其制备工艺及应用
WO2023212702A2 (en) * 2022-04-28 2023-11-02 Kansas State University Research Foundation Corralling amphipathic peptide colloids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672496B3 (fr) * 1990-07-18 1993-05-28 Vacsyn France Sa Compositions a base de substances hydrophobes, solubilisables dans un solvant aqueux, leur procede d'obtention, et leurs utilisations notamment dans le domaine pharmaceutique.
ES2109685T5 (es) * 1993-03-23 2005-09-01 Smithkline Beecham Biologicals S.A. Composiciones para vacunas que contienen monofosforil-lipido a 3-o-desacilado.
US5565204A (en) * 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5762943A (en) * 1996-05-14 1998-06-09 Ribi Immunochem Research, Inc. Methods of treating type I hypersensitivity using monophosphoryl lipid A
GB9612137D0 (en) * 1996-06-10 1996-08-14 Quaker Oats Co Treatment of dried fruit
CN1150001C (zh) * 1996-07-03 2004-05-19 卫材株式会社 含有脂质a类似物的注射剂及其制备方法

Also Published As

Publication number Publication date
AU763770B2 (en) 2003-07-31
KR100586804B1 (ko) 2006-06-07
CN1307483A (zh) 2001-08-08
DK1096954T3 (da) 2005-01-31
DE69920915D1 (de) 2004-11-11
DE69920915T2 (de) 2006-02-16
ES2229745T3 (es) 2005-04-16
CA2333578C (en) 2010-11-16
ATE278420T1 (de) 2004-10-15
AU5101899A (en) 2000-02-07
WO2000003744A2 (en) 2000-01-27
IL140890A0 (en) 2002-02-10
EP1096954A2 (en) 2001-05-09
CA2333578A1 (en) 2000-01-27
JP2002520373A (ja) 2002-07-09
BR9912067A (pt) 2001-04-10
EP1096954B1 (en) 2004-10-06
CN1247262C (zh) 2006-03-29
WO2000003744A3 (en) 2000-04-27
KR20010071637A (ko) 2001-07-28

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