IS5329A - Flutningskerfi fyrir antígen þar sem monoglýseríðeða díglýseríð afleiður eru ónæmisglæðar - Google Patents
Flutningskerfi fyrir antígen þar sem monoglýseríðeða díglýseríð afleiður eru ónæmisglæðarInfo
- Publication number
- IS5329A IS5329A IS5329A IS5329A IS5329A IS 5329 A IS5329 A IS 5329A IS 5329 A IS5329 A IS 5329A IS 5329 A IS5329 A IS 5329A IS 5329 A IS5329 A IS 5329A
- Authority
- IS
- Iceland
- Prior art keywords
- adjuvant
- monoglyceride
- transport system
- antigen
- antigen transport
- Prior art date
Links
- 239000002671 adjuvant Substances 0.000 title abstract 4
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- -1 are described Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Otolaryngology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cultivation Of Plants (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IS4518A IS4518A (is) | 1997-07-09 | 1997-07-09 | Nýtt lyfjaform fyrir bóluefni |
| PCT/IS1998/000006 WO1999002186A2 (en) | 1997-07-09 | 1998-07-09 | Antigen delivery system comprising monoglyceride or diglyceride derivatives as adjuvant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS5329A true IS5329A (is) | 1999-12-29 |
Family
ID=36699745
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS4518A IS4518A (is) | 1997-07-09 | 1997-07-09 | Nýtt lyfjaform fyrir bóluefni |
| IS5329A IS5329A (is) | 1997-07-09 | 1999-12-29 | Flutningskerfi fyrir antígen þar sem monoglýseríðeða díglýseríð afleiður eru ónæmisglæðar |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS4518A IS4518A (is) | 1997-07-09 | 1997-07-09 | Nýtt lyfjaform fyrir bóluefni |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6514503B1 (is) |
| EP (1) | EP1003551B1 (is) |
| JP (1) | JP2001509491A (is) |
| KR (1) | KR20010021622A (is) |
| CN (1) | CN1202863C (is) |
| AT (1) | ATE329617T1 (is) |
| AU (1) | AU745849B2 (is) |
| BR (1) | BR9810568A (is) |
| CA (1) | CA2295237A1 (is) |
| DE (1) | DE69834921T2 (is) |
| ES (1) | ES2267189T3 (is) |
| IS (2) | IS4518A (is) |
| WO (1) | WO1999002186A2 (is) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IS4518A (is) * | 1997-07-09 | 1999-01-10 | Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group | Nýtt lyfjaform fyrir bóluefni |
| ES2296390T3 (es) * | 1998-05-07 | 2008-04-16 | Corixa Corporation | Composicion coadyuvante y procedimiento para su uso. |
| IL146382A0 (en) * | 1999-05-13 | 2002-07-25 | American Cyanamid Co | Adjuvant combination formulations |
| ATE378067T1 (de) * | 1999-08-18 | 2007-11-15 | Industy Academic Cooperation F | Agent zur induktion einer immunologischen toleranz |
| US7384640B1 (en) * | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
| GB0007465D0 (en) * | 2000-03-29 | 2000-05-17 | Amersham Pharm Biotech Uk Ltd | Substrate for a lipase enzyme assay |
| WO2001097841A2 (en) * | 2000-06-22 | 2001-12-27 | American Cyanamid Company | Qs-21 and il-12 as an adjuvant combination |
| HRP20030355A2 (en) * | 2000-11-10 | 2005-04-30 | Wyeth Holdings Corporation | Adjuvant combination formulations |
| DE60234695D1 (de) * | 2001-06-07 | 2010-01-21 | Univ Colorado | Mutantenformen von cholera holotoxin als adjuvans |
| BR0210216A (pt) | 2001-06-07 | 2004-06-08 | Wyeth Corp | Holotoxina do cólera imunogênica, mutante (ct-crm), composição imunogênica, métodos para aumentar a resposta imune de um hospedeiro vertebrado a um antìgeno, e para produzir uma holotoxina do cólera imunogênica, mutante, sequência ou molécula de ácido nucleico isolado e purificado, célula hospedeira, e, uso de uma holotoxina do cólera mutante |
| US20040241310A1 (en) * | 2001-08-16 | 2004-12-02 | Sveibjorn Gizurarson | Method of producing antibodies ex-vivo |
| WO2003047493A2 (en) * | 2001-12-03 | 2003-06-12 | Dor Biopharma Inc. | Stabilized reverse micelle compositions and uses thereof |
| US20050163787A1 (en) * | 2002-02-25 | 2005-07-28 | Lyfjathroun Hf, Biopharmaceutical | Immunological adjuvant |
| WO2003070280A2 (en) * | 2002-02-25 | 2003-08-28 | Lyfjathroun Hf | Absorption enhancing agent |
| US6855332B2 (en) * | 2002-07-03 | 2005-02-15 | Lyfjathroun Hf. | Absorption promoting agent |
| CN1720437A (zh) * | 2002-11-21 | 2006-01-11 | 札幌免疫诊断研究所 | 唾液的采集及回收器具 |
| WO2004056314A2 (en) * | 2002-12-17 | 2004-07-08 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of y2 receptor-binding peptides and methods for treating and preventing obesity |
| US8685718B2 (en) * | 2003-05-20 | 2014-04-01 | New York University | Mucosal immunization to prevent prion infection |
| WO2005019412A2 (en) | 2003-05-20 | 2005-03-03 | New York University | Mucosal immunization to prevent prion infection |
| US20060264505A1 (en) * | 2003-11-07 | 2006-11-23 | Stiefel Laboratories, Inc. | Dermatological compositions |
| US20050100621A1 (en) * | 2003-11-07 | 2005-05-12 | Popp Karl F. | Dermatological compositions |
| CA2545325C (en) * | 2003-11-10 | 2015-01-13 | Uab Research Foundation | Compositions for reducing bacterial carriage and cns invasion and methods of using same |
| WO2007015441A1 (ja) | 2005-08-01 | 2007-02-08 | Hisamitsu Pharmaceutical Co., Inc. | 経皮または経粘膜投与のためのアジュバントおよび製剤 |
| CA2661210A1 (en) * | 2006-08-17 | 2008-02-21 | The Uab Research Foundation | Diagnosing pneumococcal pneumonia |
| JP5275047B2 (ja) * | 2007-01-31 | 2013-08-28 | 久光製薬株式会社 | 経皮または経粘膜投与のためのアジュバントおよびこれを含む医薬製剤 |
| BRPI0721702A2 (pt) * | 2007-05-23 | 2013-01-15 | Uab Research Foundation | neuraminidase pneumocàcica destoxificada ou uma porÇço antigÊnica da mesma, composiÇço, mÉtodos para reduzir ou prevenir a portabilidade nasal pneumocàcica em um indivÍduo, e para reduzir ou prevenir a infecÇço pneumocàcica em um indivÍduo, e, recipiente |
| EP2344152A4 (en) * | 2008-10-08 | 2013-04-03 | Immune Solutions Ltd | ORAL VACCINES FOR PRODUCING MUCOSAL IMMUNITY |
| CN106386848B (zh) * | 2009-03-11 | 2022-01-11 | 阿克苏诺贝尔化学品国际有限公司 | 包含草甘膦和烷氧基化甘油酯的除草配制剂 |
| WO2010114169A1 (en) * | 2009-03-31 | 2010-10-07 | Japan As Represented By The Director-General Of National Institute Of Infectious Diseases | Method for prophylaxis of influenza using vaccine for intranasal administration |
| CA2793959C (en) | 2010-03-25 | 2019-06-04 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| LT2691530T (lt) | 2011-06-10 | 2018-08-10 | Oregon Health & Science University | Cmv glikoproteinai ir rekombinantiniai vektoriai |
| EP2568289A3 (en) | 2011-09-12 | 2013-04-03 | International AIDS Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| EP2586461A1 (en) | 2011-10-27 | 2013-05-01 | Christopher L. Parks | Viral particles derived from an enveloped virus |
| EP2679596B1 (en) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 env glycoprotein variant |
| EP2848937A1 (en) | 2013-09-05 | 2015-03-18 | International Aids Vaccine Initiative | Methods of identifying novel HIV-1 immunogens |
| US10058604B2 (en) | 2013-10-07 | 2018-08-28 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| EP3064218B1 (en) | 2013-10-31 | 2019-06-19 | Hisamitsu Pharmaceutical Co., Inc. | Adjuvant composition |
| US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| CU24534B1 (es) * | 2017-11-06 | 2021-07-02 | Ct Inmunologia Molecular | Adyuvantes nano-particulados que contienen variantes sintéticas del gangliósido gm3 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE545978A (is) * | 1955-03-11 | |||
| FR2253499B1 (is) * | 1973-12-10 | 1977-11-04 | Fabre Sa Pierre | |
| US4420484A (en) | 1979-08-13 | 1983-12-13 | Sterling Drug Inc. | Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use therof |
| DE3225706C2 (de) * | 1982-07-09 | 1984-04-26 | A. Nattermann & Cie GmbH, 5000 Köln | Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen |
| JPS60149510A (ja) | 1984-01-13 | 1985-08-07 | Kao Corp | 農薬組成物 |
| US4610868A (en) | 1984-03-20 | 1986-09-09 | The Liposome Company, Inc. | Lipid matrix carriers for use in drug delivery systems |
| US4771571A (en) * | 1986-12-31 | 1988-09-20 | Nabisco Brands, Inc. | Method for treating pineapple to prevent pineapple fruit diseases |
| US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| EP0324455A3 (en) | 1988-01-15 | 1991-03-27 | Hans O. Ribi | Novel polymeric immunological adjuvants |
| US5190748A (en) * | 1988-11-22 | 1993-03-02 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
| US5177091A (en) * | 1990-12-06 | 1993-01-05 | Ciba-Geigy Corporation | Use of carbazones as novel active ingredients in medicaments |
| DK0575545T3 (da) * | 1991-03-15 | 2003-09-15 | Amgen Inc | Pegylering af polypeptider |
| AU668509B2 (en) | 1991-04-19 | 1996-05-09 | Affinity Biotech, Inc. | Convertible microemulsion formulations |
| CA2083553A1 (en) | 1991-11-25 | 1993-05-26 | Kuniharu Seki | Immunogen composition |
| GB9207799D0 (en) * | 1992-04-09 | 1992-05-27 | Procter & Gamble | Aqueous compositions |
| US5314685A (en) * | 1992-05-11 | 1994-05-24 | Agouron Pharmaceuticals, Inc. | Anhydrous formulations for administering lipophilic agents |
| ATE196254T1 (de) * | 1992-10-16 | 2000-09-15 | Ibah Inc | Konvertierbare mikroemulsionsformulierungen |
| IT1255895B (it) * | 1992-10-20 | 1995-11-17 | Laura Chiodini | Composizioni farmaceutiche contenenti una calcitonina |
| CA2153780C (en) | 1993-01-15 | 2004-04-13 | Micro Vesicular Systems, Inc. | Method of inhibiting viral reproduction |
| DK17093D0 (da) * | 1993-02-15 | 1993-02-15 | Lyfjathroun H F | Farmaceutisk praeparat til topisk administrering af antigener og/eller vacciner til pattedyr via slimhinder |
| US5359030A (en) * | 1993-05-10 | 1994-10-25 | Protein Delivery, Inc. | Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same |
| GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| ES2141950T3 (es) * | 1994-08-05 | 2000-04-01 | Inpharma Sa | Composiciones que contienen troxerutina complejada con fosfatidilcolina para el tratamiento topico de la impotencia erectil. |
| FR2729307B1 (fr) * | 1995-01-18 | 1997-04-18 | Seppic Sa | Utilisation d'esters d'acides gras ethoxyles comme composants auto-emulsionnables notamment utiles pour la preparation de produits de traitement phytosanitaires ou de medicaments a usage veterinaire ou humain |
| US5744137A (en) * | 1995-02-06 | 1998-04-28 | The United States Of America As Represented By The Secretary Of The Agriculture | Oil emulsion vaccines prepared with animal, vegetable, and synthetic oils using a mixture of nonionic surfactants |
| US6008228A (en) * | 1995-06-06 | 1999-12-28 | Hoffman-La Roche Inc. | Pharmaceutical compositions containing proteinase inhibitors |
| EP0833621B1 (en) * | 1995-06-09 | 2002-01-30 | R.P. Scherer Technologies, Inc. | Soft gelatin capsules containing particulate material |
| DE69636889T2 (de) * | 1995-11-30 | 2007-12-06 | Nof Corp. | Öladjuvierter Impfstoff und Verfahren zu seiner Herstellung |
| SE9602280D0 (sv) * | 1996-06-10 | 1996-06-10 | Pharmatrix Ab | Immunstimulerande lipidformulering |
| ID18079A (id) * | 1996-08-26 | 1998-02-26 | Takeda Chemical Industries Ltd | Komposisi farmasi yang mengandung bahan pemercepat osteogenesis |
| IS4518A (is) * | 1997-07-09 | 1999-01-10 | Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group | Nýtt lyfjaform fyrir bóluefni |
| FR2773489B1 (fr) * | 1998-01-15 | 2001-03-23 | Immunotech Sa | Nouvelle composition destinee a la voie oromuqueuse notamment pernasale |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| EP1034792A1 (en) * | 1999-03-11 | 2000-09-13 | Pasteur Merieux Serums Et Vaccins | Intranasal delivery of pneumococcal polysaccharide vaccines |
| US6458383B2 (en) * | 1999-08-17 | 2002-10-01 | Lipocine, Inc. | Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin |
| US6468559B1 (en) * | 2000-04-28 | 2002-10-22 | Lipocine, Inc. | Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods |
| US6495596B1 (en) * | 2001-03-23 | 2002-12-17 | Biozibe Laboratories, Inc. | Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase-2 |
| US6855332B2 (en) * | 2002-07-03 | 2005-02-15 | Lyfjathroun Hf. | Absorption promoting agent |
-
1997
- 1997-07-09 IS IS4518A patent/IS4518A/is unknown
-
1998
- 1998-07-09 JP JP2000501776A patent/JP2001509491A/ja active Pending
- 1998-07-09 EP EP98935262A patent/EP1003551B1/en not_active Expired - Lifetime
- 1998-07-09 AU AU84598/98A patent/AU745849B2/en not_active Ceased
- 1998-07-09 US US09/112,684 patent/US6514503B1/en not_active Expired - Fee Related
- 1998-07-09 KR KR1020007000180A patent/KR20010021622A/ko not_active Ceased
- 1998-07-09 CA CA002295237A patent/CA2295237A1/en not_active Abandoned
- 1998-07-09 CN CNB988069660A patent/CN1202863C/zh not_active Expired - Fee Related
- 1998-07-09 WO PCT/IS1998/000006 patent/WO1999002186A2/en active IP Right Grant
- 1998-07-09 BR BR9810568-0A patent/BR9810568A/pt not_active Application Discontinuation
- 1998-07-09 AT AT98935262T patent/ATE329617T1/de not_active IP Right Cessation
- 1998-07-09 DE DE69834921T patent/DE69834921T2/de not_active Expired - Fee Related
- 1998-07-09 ES ES98935262T patent/ES2267189T3/es not_active Expired - Lifetime
-
1999
- 1999-12-29 IS IS5329A patent/IS5329A/is unknown
-
2002
- 2002-07-12 US US10/195,226 patent/US20030099659A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030099659A1 (en) | 2003-05-29 |
| KR20010021622A (ko) | 2001-03-15 |
| IS4518A (is) | 1999-01-10 |
| CA2295237A1 (en) | 1999-01-21 |
| AU745849B2 (en) | 2002-04-11 |
| CN1262626A (zh) | 2000-08-09 |
| DE69834921T2 (de) | 2007-01-18 |
| BR9810568A (pt) | 2000-09-19 |
| AU8459898A (en) | 1999-02-08 |
| WO1999002186A2 (en) | 1999-01-21 |
| JP2001509491A (ja) | 2001-07-24 |
| CN1202863C (zh) | 2005-05-25 |
| ATE329617T1 (de) | 2006-07-15 |
| EP1003551B1 (en) | 2006-06-14 |
| ES2267189T3 (es) | 2007-03-01 |
| WO1999002186A3 (en) | 1999-04-01 |
| US6514503B1 (en) | 2003-02-04 |
| DE69834921D1 (de) | 2006-07-27 |
| EP1003551A2 (en) | 2000-05-31 |
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