DE69726712D1 - Iscom oder iscom-matrix, welche einen gegen die schleimhaut gerichteten wirkstoff und ein antigen enthält - Google Patents

Iscom oder iscom-matrix, welche einen gegen die schleimhaut gerichteten wirkstoff und ein antigen enthält

Info

Publication number
DE69726712D1
DE69726712D1 DE69726712T DE69726712T DE69726712D1 DE 69726712 D1 DE69726712 D1 DE 69726712D1 DE 69726712 T DE69726712 T DE 69726712T DE 69726712 T DE69726712 T DE 69726712T DE 69726712 D1 DE69726712 D1 DE 69726712D1
Authority
DE
Germany
Prior art keywords
iscom
mucutine
antique
matrix
agent against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69726712T
Other languages
English (en)
Other versions
DE69726712T2 (de
Inventor
Bror Morein
Bengtsson Karin Loevgren
Jill Ekstroem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69726712D1 publication Critical patent/DE69726712D1/de
Application granted granted Critical
Publication of DE69726712T2 publication Critical patent/DE69726712T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69726712T 1996-02-21 1997-02-20 Iscom oder iscom-matrix, welche einen gegen die schleimhaut gerichteten wirkstoff und ein antigen enthält Expired - Lifetime DE69726712T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9600647A SE9600647D0 (sv) 1996-02-21 1996-02-21 Ny användning
PCT/SE1997/000289 WO1997030728A1 (en) 1996-02-21 1997-02-20 Iscom or iscom-matrix comprising a mucus targetting substance and optionally, an antigen

Publications (2)

Publication Number Publication Date
DE69726712D1 true DE69726712D1 (de) 2004-01-22
DE69726712T2 DE69726712T2 (de) 2004-10-07

Family

ID=20401481

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69726712T Expired - Lifetime DE69726712T2 (de) 1996-02-21 1997-02-20 Iscom oder iscom-matrix, welche einen gegen die schleimhaut gerichteten wirkstoff und ein antigen enthält

Country Status (12)

Country Link
US (1) US6607732B2 (de)
EP (1) EP0889736B1 (de)
JP (1) JP2000504746A (de)
AT (1) ATE255905T1 (de)
AU (1) AU719084B2 (de)
CA (1) CA2247522C (de)
DE (1) DE69726712T2 (de)
DK (1) DK0889736T3 (de)
ES (1) ES2210495T3 (de)
NZ (1) NZ331403A (de)
SE (1) SE9600647D0 (de)
WO (1) WO1997030728A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
PT1077722E (pt) 1998-05-22 2006-12-29 Coley Pharm Group Inc Produtos e composições para utilização na indução da imunidade mucosal
US7041296B1 (en) * 1999-11-12 2006-05-09 The United States Of America As Represented By The Department Of Health And Human Services Methods of treating inflammatory bowel disease using cholera toxin B subunit
US7713942B2 (en) * 2001-04-04 2010-05-11 Nordic Vaccine Technology A/S Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
SE0202110D0 (sv) 2002-07-05 2002-07-05 Isconova Ab Iscom preparation and use thereof
SE0301998D0 (sv) 2003-07-07 2003-07-07 Isconova Ab Quil A fraction with low toxicity and use thereof
DK1838341T3 (da) 2005-01-20 2013-11-04 Isconova Ab Vaccinesammensætning omfattende et fibronectin bindende protein eller et fibronectinbindende peptid
CN101835488B (zh) 2007-09-04 2018-10-26 美国政府(由卫生和人类服务部、疾病控制和预防中心的部长所代表) 轮状病毒的热灭活
GB0803076D0 (en) 2008-02-20 2008-03-26 Univ Ghent Mucosal Membrane Receptor and uses thereof
ES2325243B1 (es) * 2008-02-27 2011-05-04 Universidad De Granada Antigeno recombinante.
KR20130095251A (ko) 2010-07-23 2013-08-27 이스코노바 에이비 인플루엔자 백신
EP3251692B1 (de) 2011-05-13 2023-09-27 Zoetis Services LLC Immunogene hendra- und nipah-virus-g-glycoprotein-zusammensetzungen
EP4176871A1 (de) 2011-10-03 2023-05-10 Canqura Oncology Ab Nanopartikel, verfahren zur herstellung und verwendung davon als träger für amphipatische hydrophobische moleküle in arzneimitteln mit krebsbehandlung und lebensmittelverwandten verbindungen
WO2014124228A1 (en) 2013-02-07 2014-08-14 Children's Medical Center Corporation Protein antigens that provide protection against pneumococcal colonization and/or disease
WO2014163558A1 (en) 2013-04-01 2014-10-09 Moreinx Ab Nanoparticles, composed of sterol and saponin from quillaja saponaria molina process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds
CA2931855A1 (en) 2013-12-16 2015-06-25 Nigel Edwards Hendra and nipah virus g glycoprotein immunogenic compositions
EP3344291A4 (de) 2015-09-03 2019-04-10 Novavax, Inc. Impfstoffzusammensetzungen mit verbesserter stabilität und immunogenität
WO2019023196A1 (en) 2017-07-24 2019-01-31 Novavax, Inc. METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISEASE
IL305911B1 (en) 2018-03-19 2024-09-01 Novavax Inc Multifunctional nanoparticle vaccines for influenza
US10953089B1 (en) 2020-01-27 2021-03-23 Novavax, Inc. Coronavirus vaccine formulations
GB202209588D0 (en) 2022-06-29 2022-08-10 Plant Bioscience Ltd Methods and compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6290962B1 (en) * 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection

Also Published As

Publication number Publication date
AU2238597A (en) 1997-09-10
NZ331403A (en) 2000-02-28
EP0889736A1 (de) 1999-01-13
CA2247522C (en) 2009-12-29
SE9600647D0 (sv) 1996-02-21
ATE255905T1 (de) 2003-12-15
US6607732B2 (en) 2003-08-19
AU719084B2 (en) 2000-05-04
DE69726712T2 (de) 2004-10-07
ES2210495T3 (es) 2004-07-01
EP0889736B1 (de) 2003-12-10
WO1997030728A1 (en) 1997-08-28
CA2247522A1 (en) 1997-08-28
JP2000504746A (ja) 2000-04-18
US20020131982A1 (en) 2002-09-19
DK0889736T3 (da) 2004-04-19

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