ATE255905T1 - Iscom oder iscom-matrix, welche einen gegen die schleimhaut gerichteten wirkstoff und ein antigen enthält - Google Patents
Iscom oder iscom-matrix, welche einen gegen die schleimhaut gerichteten wirkstoff und ein antigen enthältInfo
- Publication number
- ATE255905T1 ATE255905T1 AT97905541T AT97905541T ATE255905T1 AT E255905 T1 ATE255905 T1 AT E255905T1 AT 97905541 T AT97905541 T AT 97905541T AT 97905541 T AT97905541 T AT 97905541T AT E255905 T1 ATE255905 T1 AT E255905T1
- Authority
- AT
- Austria
- Prior art keywords
- iscom
- mucosa
- antigen
- active ingredient
- matrix
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 239000011159 matrix material Substances 0.000 title 1
- 210000004877 mucosa Anatomy 0.000 title 1
- 230000002163 immunogen Effects 0.000 abstract 2
- 210000004400 mucous membrane Anatomy 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 210000003563 lymphoid tissue Anatomy 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 230000010415 tropism Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9600647A SE9600647D0 (sv) | 1996-02-21 | 1996-02-21 | Ny användning |
| PCT/SE1997/000289 WO1997030728A1 (en) | 1996-02-21 | 1997-02-20 | Iscom or iscom-matrix comprising a mucus targetting substance and optionally, an antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE255905T1 true ATE255905T1 (de) | 2003-12-15 |
Family
ID=20401481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97905541T ATE255905T1 (de) | 1996-02-21 | 1997-02-20 | Iscom oder iscom-matrix, welche einen gegen die schleimhaut gerichteten wirkstoff und ein antigen enthält |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6607732B2 (de) |
| EP (1) | EP0889736B1 (de) |
| JP (1) | JP2000504746A (de) |
| AT (1) | ATE255905T1 (de) |
| AU (1) | AU719084B2 (de) |
| CA (1) | CA2247522C (de) |
| DE (1) | DE69726712T2 (de) |
| DK (1) | DK0889736T3 (de) |
| ES (1) | ES2210495T3 (de) |
| NZ (1) | NZ331403A (de) |
| SE (1) | SE9600647D0 (de) |
| WO (1) | WO1997030728A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| IL139813A0 (en) | 1998-05-22 | 2002-02-10 | Loeb Health Res Inst At The Ot | Methods and products for inducing mucosal immunity |
| US7041296B1 (en) * | 1999-11-12 | 2006-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of treating inflammatory bowel disease using cholera toxin B subunit |
| US7713942B2 (en) * | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
| SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
| SE0301998D0 (sv) * | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
| BRPI0606481A2 (pt) | 2005-01-20 | 2009-06-30 | Isconova Ab | composição de vacina compreendendo uma proteìna de ligação a fibronectina ou um peptìdeo de ligação a fibronectina |
| ES2566527T3 (es) | 2007-09-04 | 2016-04-13 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention | Inactivación térmica de rotavirus |
| GB0803076D0 (en) * | 2008-02-20 | 2008-03-26 | Univ Ghent | Mucosal Membrane Receptor and uses thereof |
| ES2325243B1 (es) * | 2008-02-27 | 2011-05-04 | Universidad De Granada | Antigeno recombinante. |
| WO2010077717A1 (en) | 2008-12-09 | 2010-07-08 | Novavax, Inc. | Modified rsv f proteins and methods of their use |
| EP2595653B1 (de) | 2010-07-23 | 2017-06-28 | Novavax AB | Influenza-impfstoff |
| UA114086C2 (xx) | 2011-05-13 | 2017-04-25 | Імуногенна композиція глікопротеїну g вірусу hendra і/або nipah | |
| TR201808733T4 (tr) | 2011-10-03 | 2018-07-23 | Mx Adjuvac Ab | Kanser tedavisini ve gıda ile ilgili bileşikleri içeren tıp alanlarında amfipatik veya hidrofobik moleküller için taşıyıcı olarak nano-parçacıklar, preparasyon için proses ve bunların kullanımı. |
| CA2900008C (en) | 2013-02-07 | 2025-10-07 | Children's Medical Center Corporation | PROTEIN ANTIGENS THAT CONFER PROTECTION AGAINST COLONIZATION AND/OR PNEUMOCOCCAL DISEASE |
| WO2014163558A1 (en) | 2013-04-01 | 2014-10-09 | Moreinx Ab | Nanoparticles, composed of sterol and saponin from quillaja saponaria molina process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds |
| EP3082856A1 (de) | 2013-12-16 | 2016-10-26 | Zoetis Services LLC | Immunogene hendra- und nipah-virus-g-glycoprotein-zusammensetzungen |
| MX2018002728A (es) | 2015-09-03 | 2018-09-05 | Novavax Inc | Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas. |
| CN111148509A (zh) | 2017-07-24 | 2020-05-12 | 诺瓦瓦克斯股份有限公司 | 治疗呼吸系统疾病的方法和组合物 |
| IL277274B2 (en) | 2018-03-19 | 2024-02-01 | Novavax Inc | Multifunctional nanoparticle vaccines for influenza |
| US10953089B1 (en) | 2020-01-27 | 2021-03-23 | Novavax, Inc. | Coronavirus vaccine formulations |
| GB202209588D0 (en) | 2022-06-29 | 2022-08-10 | Plant Bioscience Ltd | Methods and compositions |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290962B1 (en) * | 1992-11-03 | 2001-09-18 | Oravax, Inc. | Urease-based vaccine and treatment for helicobacter infection |
-
1996
- 1996-02-21 SE SE9600647A patent/SE9600647D0/xx unknown
-
1997
- 1997-02-20 CA CA002247522A patent/CA2247522C/en not_active Expired - Lifetime
- 1997-02-20 NZ NZ331403A patent/NZ331403A/en not_active IP Right Cessation
- 1997-02-20 WO PCT/SE1997/000289 patent/WO1997030728A1/en not_active Ceased
- 1997-02-20 JP JP9530070A patent/JP2000504746A/ja active Pending
- 1997-02-20 AU AU22385/97A patent/AU719084B2/en not_active Expired
- 1997-02-20 DK DK97905541T patent/DK0889736T3/da active
- 1997-02-20 AT AT97905541T patent/ATE255905T1/de not_active IP Right Cessation
- 1997-02-20 DE DE69726712T patent/DE69726712T2/de not_active Expired - Lifetime
- 1997-02-20 EP EP97905541A patent/EP0889736B1/de not_active Expired - Lifetime
- 1997-02-20 ES ES97905541T patent/ES2210495T3/es not_active Expired - Lifetime
-
1998
- 1998-08-20 US US09/137,236 patent/US6607732B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2210495T3 (es) | 2004-07-01 |
| SE9600647D0 (sv) | 1996-02-21 |
| AU719084B2 (en) | 2000-05-04 |
| CA2247522A1 (en) | 1997-08-28 |
| DE69726712T2 (de) | 2004-10-07 |
| EP0889736A1 (de) | 1999-01-13 |
| JP2000504746A (ja) | 2000-04-18 |
| AU2238597A (en) | 1997-09-10 |
| DE69726712D1 (de) | 2004-01-22 |
| NZ331403A (en) | 2000-02-28 |
| EP0889736B1 (de) | 2003-12-10 |
| CA2247522C (en) | 2009-12-29 |
| DK0889736T3 (da) | 2004-04-19 |
| US6607732B2 (en) | 2003-08-19 |
| US20020131982A1 (en) | 2002-09-19 |
| WO1997030728A1 (en) | 1997-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0889736 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |