ES2134797T3 - Peptidos y fragmentos de peptidos terapeuticamente utiles. - Google Patents

Peptidos y fragmentos de peptidos terapeuticamente utiles.

Info

Publication number
ES2134797T3
ES2134797T3 ES92905196T ES92905196T ES2134797T3 ES 2134797 T3 ES2134797 T3 ES 2134797T3 ES 92905196 T ES92905196 T ES 92905196T ES 92905196 T ES92905196 T ES 92905196T ES 2134797 T3 ES2134797 T3 ES 2134797T3
Authority
ES
Spain
Prior art keywords
peptides
fragments
therapeutically useful
oncogen
presented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92905196T
Other languages
English (en)
Inventor
Gustav Gaudernack
Tobias D Y Gedde-Dahl
Jon Amund Eriksen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norsk Hydro ASA
Original Assignee
Norsk Hydro ASA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro ASA filed Critical Norsk Hydro ASA
Application granted granted Critical
Publication of ES2134797T3 publication Critical patent/ES2134797T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE PRESENTAN PEPTIDOS SINTETICOS Y FRAGMENTOS DE PRODUCTOS DE LA PROTEINA DEL ONCOGEN QUE PRODUCEN LA INMUNIDAD CELULAR T, PARA SU USO EN VACUNAS CONTRA EL CANCER Y COMPUESTOS PARA EL TRATAMIENTO DEL CANCER.
ES92905196T 1991-02-26 1992-02-21 Peptidos y fragmentos de peptidos terapeuticamente utiles. Expired - Lifetime ES2134797T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919103974A GB9103974D0 (en) 1991-02-26 1991-02-26 Therapeutically useful peptides or peptide fragments

Publications (1)

Publication Number Publication Date
ES2134797T3 true ES2134797T3 (es) 1999-10-16

Family

ID=10690575

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92905196T Expired - Lifetime ES2134797T3 (es) 1991-02-26 1992-02-21 Peptidos y fragmentos de peptidos terapeuticamente utiles.

Country Status (14)

Country Link
US (1) US5961978A (es)
EP (1) EP0529023B1 (es)
AT (1) ATE181337T1 (es)
AU (1) AU660452B2 (es)
CA (1) CA2077537C (es)
DE (1) DE69229428T2 (es)
DK (1) DK0529023T3 (es)
ES (1) ES2134797T3 (es)
FI (1) FI108139B (es)
GB (2) GB9103974D0 (es)
GR (1) GR3031234T3 (es)
HK (1) HK1011370A1 (es)
NO (1) NO923953L (es)
WO (1) WO1992014756A1 (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2124595A1 (en) * 1992-09-30 1994-04-14 Hanswalter Zentgraf Process for detecting p53-specific antibodies
AU6363094A (en) * 1993-03-15 1994-10-11 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Peptide coated dendritic cells as immunogens
AT399656B (de) * 1993-03-19 1995-06-26 Boehringer Ingelheim Int Verfahren zur herstellung von krebsvakzinen
GB9422814D0 (en) * 1994-11-11 1995-01-04 Medinnova Sf Chemical method
US6156316A (en) * 1995-05-08 2000-12-05 Sloan-Kettering Institute For Cancer Research Oncogene fusion protein peptide vaccines
US6365151B1 (en) 1996-01-19 2002-04-02 Philadelphia Health And Educational Corporation Cellular immunogens comprising cognate proto-oxogenes
US7709002B1 (en) * 1996-04-19 2010-05-04 The United States Of America As Represented By The Department Of Health And Human Services Mutated ras peptides for generation of CD8+Cytotoxic T lymphocytes
EP0895538B1 (en) 1996-04-19 2002-07-17 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Mutated ras peptides for generation of cd8+ cytotoxic t lymphocytes
US6069229A (en) * 1997-03-07 2000-05-30 Schering Corporation Mammalian proteinases; oxidoreductases; related reagents
GB2328689A (en) * 1997-08-27 1999-03-03 Norsk Hydro As Peptides based on the p21 ras proto-oncogene protein for the treatment of cancer
NO314086B1 (no) 1998-05-08 2003-01-27 Gemvax As Peptider og farmasöytiske sammensetninger inneholdende disse, nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slike DNA-sekvenser samt anvendelse av disse for fremstilling avfarmasöytiske preparater til
NO315238B1 (no) 1998-05-08 2003-08-04 Gemvax As Peptider som stammer fra leserammeforskyvingsmutasjoner i TBF<beta>II- eller BAX-genet, og farmasöytiske sammensetninger inneholdende disse,nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slikenukleinsy
US7030211B1 (en) * 1998-07-08 2006-04-18 Gemvax As Antigenic peptides derived from telomerase
NO309798B1 (no) * 1999-04-30 2001-04-02 Targovax As Peptidblanding, samt farmasoytisk sammensetning og kreftvaksine som innbefatter peptidblandingen
US7700359B2 (en) * 2000-06-02 2010-04-20 Novartis Vaccines And Diagnostics, Inc. Gene products differentially expressed in cancerous cells
GB0031430D0 (en) 2000-12-22 2001-02-07 Norsk Hydro As Polypeptides
GB0105238D0 (en) * 2001-03-02 2001-04-18 Norsk Hydro As Vaccines
JP4376629B2 (ja) * 2002-01-08 2009-12-02 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 癌性胸部細胞において差次的に発現された遺伝子産物およびその使用方法
US20030206916A1 (en) * 2002-05-03 2003-11-06 Rush-Presbyterian-St. Luke's Medical Center Immunogenic peptides
ES2676503T3 (es) * 2002-12-16 2018-07-20 Globeimmune, Inc. Vacunas basadas en levadura como inmunoterapia
US8343502B2 (en) 2002-12-16 2013-01-01 Globeimmune, Inc. Yeast-based vaccines as immunotherapy
US7439042B2 (en) * 2002-12-16 2008-10-21 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
EP2460533A3 (en) 2004-10-18 2014-01-08 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
US9732131B2 (en) 2006-02-27 2017-08-15 Calviri, Inc. Identification and use of novopeptides for the treatment of cancer
US7745128B2 (en) * 2006-03-27 2010-06-29 Globeimmune, Inc. Ras mutation and compositions and methods related thereto
US20080079547A1 (en) * 2006-09-29 2008-04-03 Sensormatic Electronics Corporation Radio frequency identification reader having a signal canceller and method thereof
JP2012503011A (ja) 2008-09-19 2012-02-02 グローブイミューン，インコーポレイテッド 慢性ｃ型肝炎ウイルス感染の免疫療法
GB0821616D0 (en) 2008-11-26 2008-12-31 Lytix Biopharma As Compounds
EP3369432A1 (en) 2013-12-09 2018-09-05 Targovax Asa A peptide mixture
JP2017514847A (ja) * 2014-05-06 2017-06-08 タルゴバックス エーエスエー 突然変異ｒａｓペプチド及び化学療法剤を含むペプチドワクチン
BR112019015797A2 (pt) 2017-02-01 2020-03-17 Modernatx, Inc. Composições de mrna terapêuticas imunomoduladoras que codificam peptídeos de mutação de oncogene de ativação
WO2018145020A1 (en) * 2017-02-03 2018-08-09 The Medical College Of Wisconsin, Inc. Kras peptide vaccine compositions and method of use
CA3065325A1 (en) 2017-06-02 2018-12-06 Arizona Board Of Regents On Behalf Of Arizona State University A method to create personalized cancer vaccines
WO2019055618A1 (en) 2017-09-15 2019-03-21 Arizona Board Of Regents On Behalf Of Arizona State University METHODS OF CLASSIFYING RESPONSES TO ANTICANCER IMMUNOTHERAPY
SG11202008433QA (en) * 2018-03-02 2020-09-29 Elicio Therapeutics Inc Compounds including a mutant kras sequence and a lipid and uses thereof
CN114573688A (zh) * 2018-10-19 2022-06-03 杭州纽安津生物科技有限公司 通用性多肽疫苗及其在制备治疗/预防胰腺癌药物中的应用
EP4038222A4 (en) 2019-10-02 2023-10-18 Arizona Board of Regents on behalf of Arizona State University METHODS AND COMPOSITIONS FOR IDENTIFYING NEOANTIGENS FOR USE IN THE TREATMENT AND PREVENTION OF CANCER
US11421015B2 (en) 2020-12-07 2022-08-23 Think Therapeutics, Inc. Method of compact peptide vaccines using residue optimization
US11058751B1 (en) 2020-11-20 2021-07-13 Think Therapeutics, Inc. Compositions for optimized RAS peptide vaccines
US11464842B1 (en) 2021-04-28 2022-10-11 Think Therapeutics, Inc. Compositions and method for optimized peptide vaccines using residue optimization

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1252046A (en) * 1982-11-04 1989-04-04 Martin J. Cline Methods for oncogenic detection
CA1219232A (en) * 1983-08-17 1987-03-17 Richard A. Lerner Polypeptide-induced monoclonal receptors to protein ligands
CA1296660C (en) * 1985-01-29 1992-03-03 Walter P. Carney Monoclonal antibody against a ras oncogene p21 related dodecapeptide
US4898932A (en) * 1985-01-29 1990-02-06 E. I. Du Pont De Nemours And Company Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
US5100664A (en) * 1985-09-20 1992-03-31 Cetus Corporation Human IL-2 as a vaccine adjuvant
DK354487A (da) * 1986-07-11 1988-01-12 Noboru Yanaihara Oncogen-relaterede peptider
CA1339069C (en) * 1987-11-09 1997-07-29 Henry Lee Niman Polypeptide-induced monoclonal receptors to protein ligand
US4957859A (en) * 1988-02-16 1990-09-18 Hoffmann-La Roche Inc. Antibodies for transforming ras protein
EP0370012A1 (en) * 1988-03-08 1990-05-30 E.I. Du Pont De Nemours And Company Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
EP0411018B1 (en) * 1988-04-22 1997-06-04 Oncogene Science, Inc. Detection, quantitation and classification of ras proteins in body fluids and tissues
EP0354808B1 (en) * 1988-08-12 1997-12-03 Ligand Pharmaceuticals Incorporated Polypeptide-induced monoclonal receptors to protein ligands
ES2070492T3 (es) * 1990-01-26 1995-06-01 Washington Res Found Reactividad inmunitaria para oncogenes expresados activos para diagnostico y tratamiento de estados malignos.

Also Published As

Publication number Publication date
NO923953L (no) 1993-03-26
NO923953D0 (no) 1992-10-12
DE69229428D1 (de) 1999-07-22
CA2077537C (en) 2000-06-13
ATE181337T1 (de) 1999-07-15
FI924069A0 (fi) 1992-09-11
GB2253211A (en) 1992-09-02
FI108139B (fi) 2001-11-30
WO1992014756A1 (en) 1992-09-03
AU1272992A (en) 1992-09-15
FI924069A (fi) 1992-09-11
GR3031234T3 (en) 1999-12-31
EP0529023A1 (en) 1993-03-03
DK0529023T3 (da) 2000-01-17
HK1011370A1 (en) 1999-07-09
AU660452B2 (en) 1995-06-29
CA2077537A1 (en) 1992-08-27
US5961978A (en) 1999-10-05
GB9204098D0 (en) 1992-04-08
DE69229428T2 (de) 2000-06-29
GB9103974D0 (en) 1991-04-10
EP0529023B1 (en) 1999-06-16

Similar Documents

Publication Publication Date Title
ES2134797T3 (es) Peptidos y fragmentos de peptidos terapeuticamente utiles.
ES2063515T3 (es) Ifn-alfa o-glucosilados.
GB2255093A (en) Hiv-1 core protein fragments
ES2196024T3 (es) Vacunas conjugadas de gangliosido-klh con qs-21.
CY1105963T1 (el) Συνθεσεις καψομepιδιακου εμβολιου του ιου του θηλωματος και μεθοδοι χρησης
ES2060310T3 (es) Utilizacion de la n-miristoil-(s)-fenilalanina para la obtencion de medicamentos destinados al tratamiento de enfermedades que hacen intervenir la miristoilacion.
AR023806A1 (es) Uso de una mezcla de peptidos para la manufactura de un agente terapeutico para la profilaxis y/o el tratamiento del cancer, las composicionesfarmaceuticas y vacunas que contienen dicha mezcla y los procedimientos de preparacion de dichas composiciones y vacunas
BR9814473A (pt) Imunógenos anti-retrovirais, preparação e uso
ES2153665T3 (es) Usos terapeuticos de productos proteicos bactericidas/incrementadores de la permeabilidad (bpi) para la meningococemia humana.
ES2194836T3 (es) Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana.
EP0511306A4 (en) Tumor killing effects of enterotoxins and related compounds
ATE212540T1 (de) Antitumorvakzine
ATE193974T1 (de) Chlamydia impfstoffen
NO179855C (no) Fremgangsmåte for fremstilling av et legemiddel
UA42741C2 (uk) Пептид маститної вакцини (варіанти), пептид складного антигенного представлення (варіанти), фармацевтична композиція (варіанти)
DE59610098D1 (de) Protein mit anti-tumorwirkung
ES2185083T3 (es) Proteina estimulante de macrofagos para el tratamiento de patologias del sistema nervioso.
DK0427633T3 (da) Anvendelse af et polypeptid med gammainterferonaktivitet til fremstilling af farmaceutiske præparater beregnet til behandling af primitiv pleuracancer
NO20000976L (no) Peptider
GT199500023A (es) Formas de dosificacion de liberacion controlada azitromicina
ITRM920091A1 (it) Uso di derivati del trenbolone per la terapia dello stress in acquacoltura.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 529023

Country of ref document: ES