ES2194836T3 - Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana. - Google Patents

Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana.

Info

Publication number
ES2194836T3
ES2194836T3 ES91917502T ES91917502T ES2194836T3 ES 2194836 T3 ES2194836 T3 ES 2194836T3 ES 91917502 T ES91917502 T ES 91917502T ES 91917502 T ES91917502 T ES 91917502T ES 2194836 T3 ES2194836 T3 ES 2194836T3
Authority
ES
Spain
Prior art keywords
peptides
human immunodeficiency
virus
vaccination
induction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91917502T
Other languages
English (en)
Inventor
Anders Vahlne
Bo Svennerholm
Lars Rymo
Stig Jeansson
Peter Horal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tripep AB
Original Assignee
Tripep AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tripep AB filed Critical Tripep AB
Application granted granted Critical
Publication of ES2194836T3 publication Critical patent/ES2194836T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

DE ACUERDO CON LA INVENCION, SE PRESENTAN PEPTIDOS QUE SE CORRESPONDEN CON EPITOPOS DE LA PROTEINA GP120 DEL VIRUS-1 DE LA INMUNODEFICIENCIA HUMANA Y ANALOGOS Y HOMOLOGOS DE LOS MISMOS. ESTOS PEPTIDOS PUEDEN UTILIZARSE SOLOS O EN COMBINACION, ACOPLADOS O NO ACOPLADOS A OTRAS MOLECULAS O SUSTRATOS. LOS PEPTIDOS SON UTILES EN LA INMUNIZACION CONTRA LA INFECCION POR EL VIRUS DE INMUNODEFICIENCIA HUMANA Y EN LA PRODUCCION DE ANTICUERPOS MONOCLONALES Y POLICLONALES. LOS PEPTIDOS SE SELECCIONAN ENTRE AQUELLOS QUE TIENEN COMBINADOS DE AMINOACIDO 151-176, 192-218, 205-230.
ES91917502T 1990-09-27 1991-09-25 Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana. Expired - Lifetime ES2194836T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58942290A 1990-09-27 1990-09-27

Publications (1)

Publication Number Publication Date
ES2194836T3 true ES2194836T3 (es) 2003-12-01

Family

ID=24357953

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91917502T Expired - Lifetime ES2194836T3 (es) 1990-09-27 1991-09-25 Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana.

Country Status (13)

Country Link
US (1) US5589175A (es)
EP (1) EP0550599B1 (es)
JP (1) JPH06501260A (es)
AT (1) ATE238065T1 (es)
AU (1) AU650911B2 (es)
CA (1) CA2091263C (es)
DE (1) DE69133242T2 (es)
ES (1) ES2194836T3 (es)
FI (1) FI931393A0 (es)
HU (1) HU9300877D0 (es)
MC (1) MC2308A1 (es)
OA (1) OA09802A (es)
WO (1) WO1992005800A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939074A (en) * 1986-12-30 1999-08-17 The United States Of America As Represented By The Department Of Health And Human Services Multideterminant peptide antigens
US5346989A (en) * 1990-08-22 1994-09-13 Syntello Vaccine Development Kb Peptides for use in induction of T cell activation against HIV-1
WO1992021377A1 (en) * 1991-06-03 1992-12-10 Syntello Inc. Peptides for use in induction of t cell activation against hiv-1
DK0601108T3 (da) * 1991-08-29 2000-04-17 Us Gov Health & Human Serv Multideterminante peptidantigener, som stimulerer T-hjælpelymfocytrespons til HIV hos en gruppe mennesker
IT1254360B (it) * 1992-05-11 1995-09-14 San Romanello Centro Fond Epitopi immunologicamente omologhi di hla e proteine del virus hiv.
DE4228787A1 (de) * 1992-08-29 1994-03-03 Chemotherapeutisches Forschungsinstitut Georg Speyer Haus Neue HIV-1-Virusisolate eines Subtyps, Vakzine gegen HIV-1-Virusinfektionen dieses Subtyps und Verfahren zu ihrer Herstellung, Verwendung der HIV-1-Virusisolate
AU6515394A (en) * 1993-04-16 1994-11-08 Syntello Vaccine Development Ab Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus
FR2707170A1 (fr) * 1993-06-04 1995-01-13 Pasteur Institut Expression des récepteurs CD4 et CD26 dans des cellules recombinantes, inhibiteurs du récepteur CD26.
FR2707169B1 (fr) * 1993-06-04 1995-09-01 Pasteur Institut Antigène cellulaire CD26 impliqué dans l'infection par un rétrovirus hiv. nouveaux inhibiteurs de l'infection par HIV. * (Dipeptidyl-peptidase IV).
DE4405810A1 (de) 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
AU2991197A (en) * 1996-04-15 1997-11-07 University Of North Carolina At Chapel Hill, The Antigenic sequences of a sperm protein and immunocontraceptive methods
US7048929B1 (en) * 1997-11-10 2006-05-23 Dana-Farber Cancer Institute, Inc. Stabilized primate lentivirus envelope glycoproteins
DK2476436T3 (en) 2006-08-11 2018-02-05 Life Sciences Res Partners Vzw Immunogenic peptides and their use in immune disorders
EP2626081B1 (en) 2008-02-14 2017-03-22 Life Sciences Research Partners VZW Immunogenic control of tumours and tumour cells
WO2009101208A2 (en) 2008-02-14 2009-08-20 Life Sciences Research Partners Vzw Immunotherapy targeting intracellular pathogens
BR112013012555B8 (pt) * 2010-11-25 2022-09-06 Imnate Sarl Peptídeo imunogênico isolado derivado de uma proteína antigênica, seus usos, método para a preparação de um peptídeo com capacidade de provocar a ativação de células nkt e método in vitro para obtenção de uma população de células nkt cd4+ antígeno específicas
GB201201511D0 (en) 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
CA2995771A1 (en) 2015-09-25 2017-03-30 Imcyse Sa Improved methods and compounds for eliminating immune responses to therapeutic agents
IL262286B2 (en) 2016-04-19 2023-12-01 Imcyse Sa Novel immunogenic peptides that bind CD1D

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE286132T1 (de) * 1984-10-18 2005-01-15 Pasteur Institut Dns-fragmente des gag-gens von lav
WO1987007616A1 (en) * 1986-06-12 1987-12-17 Biogen N.V. Peptides involved in the pathogenesis of hiv infection
US5128319A (en) * 1987-08-28 1992-07-07 Board Of Regents, The University Of Texas System Prophylaxis and therapy of acquired immunodeficiency syndrome
US5019387A (en) * 1987-09-08 1991-05-28 Duke University Production of antibodies to HIV
WO1989005820A1 (en) * 1987-12-21 1989-06-29 Arch Development Corporation Hiv-related antigens and antibodies
EP0330359A3 (en) * 1988-02-25 1991-06-05 Bio-Rad Laboratories, Inc. Composition useful in the diagnosis and treating of hiv-1 infection
AU3557889A (en) * 1988-04-20 1989-11-24 Trustees Of The University Of Pennsylvania, The Protective peptides derived from human immunodeficiency virus-1 gp160
US4943628A (en) * 1988-06-13 1990-07-24 Ortho Pharmaceutical Corporation HIV peptide-inducted T cell stimulation
CA2078545A1 (en) * 1990-04-03 1991-10-04 Timothy J. Gregory Hiv envelope polypeptides
AP237A (en) * 1990-05-29 1993-04-29 Cedars Sinai Medical Center Immunoreagents reactive with a conserved epitope of human immunodeficiency virus type 1 (HIV-1) gp120 and methods of use.
WO1992021377A1 (en) * 1991-06-03 1992-12-10 Syntello Inc. Peptides for use in induction of t cell activation against hiv-1

Also Published As

Publication number Publication date
EP0550599B1 (en) 2003-04-23
ATE238065T1 (de) 2003-05-15
CA2091263C (en) 2003-05-06
US5589175A (en) 1996-12-31
DE69133242D1 (de) 2003-05-28
FI931393A (fi) 1993-03-26
CA2091263A1 (en) 1992-03-28
AU8643591A (en) 1992-04-28
FI931393A0 (fi) 1993-03-26
MC2308A1 (fr) 1993-09-27
DE69133242T2 (de) 2004-02-19
AU650911B2 (en) 1994-07-07
EP0550599A1 (en) 1993-07-14
HU9300877D0 (en) 1993-06-28
WO1992005800A1 (en) 1992-04-16
JPH06501260A (ja) 1994-02-10
OA09802A (en) 1994-04-15

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