ES2118720T3 - Produccion y utilizacion de agentes antihelminticos e inmunogenos protectores. - Google Patents
Produccion y utilizacion de agentes antihelminticos e inmunogenos protectores.Info
- Publication number
- ES2118720T3 ES2118720T3 ES90904903T ES90904903T ES2118720T3 ES 2118720 T3 ES2118720 T3 ES 2118720T3 ES 90904903 T ES90904903 T ES 90904903T ES 90904903 T ES90904903 T ES 90904903T ES 2118720 T3 ES2118720 T3 ES 2118720T3
- Authority
- ES
- Spain
- Prior art keywords
- approximately
- protein
- complex
- production
- egpa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
- C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE DESCRIBE UN COMPLEXO DE PROTEINA CUYOS COMPONENTES SON GLICOPROTEINAS AISLABLES DE LA MEMBRANA DE PLASMA DE MICROVILLUS INTESTINAL DE UN NEMATODO PARASITICO, COMO EL HAEMONCHUS CONTORTUS. ESTE COMPLEJO INCLUYE LA PROTEINA H4.5, QUE TIENE UN PESO MOLECULAR APARENTE EN ELECTROFORESIS DE GEL DE POLIACRILAMIDA DE SULFATO DE DODECILO DE SODIO (EGPA-SDS) DE APROXIMADAMENTE 45 KD BAJO CONDICIONES REDUCTORAS Y APROXIMADAMENTE 90 KD BAJO CONDICIONES NO REDUCTORAS, ASI COMO LAS PROTEINAS H4.9 Y H5.3 QUE TIENEN PESOS MOLECULARES APARENTE EN EGPA-SDS DE APROXIMADAMENTE 49 KD Y APROXIMADAMENTE 53 KD RESPECTIVAMENTE, AMBAS BAJO CONDICIONES REDUCTORAS Y NO REDUCTORAS. EL COMPLEJO DE PROTEINA H 45 Y SUS COMPONENTES PUEDEN USARSE, OPCIONALMENTE JUNTOS CON EL YA CONOCIDO DOBLETE DE PROTEINA H110D, PARA ELABORAR UNA VACUNA QUE PUEDE REDUCIR EL PESO DE LOS GUSANOS EN LAS OVEJAS INFECTADAS CON EL HAEMONCHUS CONTORTUS CON UNA MEDIA DE 91% Y LA PRODUCCION DE HUEVOS PARASITOS CON UNA MEDIA DE 94.5%.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898906156A GB8906156D0 (en) | 1989-03-17 | 1989-03-17 | Production and use of anthelmintic agents and protective immunogens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2118720T3 true ES2118720T3 (es) | 1998-10-01 |
Family
ID=10653520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90904903T Expired - Lifetime ES2118720T3 (es) | 1989-03-17 | 1990-03-19 | Produccion y utilizacion de agentes antihelminticos e inmunogenos protectores. |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP0846760A1 (es) |
| JP (2) | JP3103592B2 (es) |
| AT (1) | ATE166231T1 (es) |
| AU (1) | AU641148B2 (es) |
| CA (2) | CA2046601C (es) |
| DE (1) | DE69032323T2 (es) |
| DK (1) | DK0463053T3 (es) |
| ES (1) | ES2118720T3 (es) |
| GB (1) | GB8906156D0 (es) |
| IN (2) | IN176658B (es) |
| NZ (1) | NZ232984A (es) |
| WO (1) | WO1990011086A1 (es) |
| ZA (1) | ZA902054B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0529019T3 (da) * | 1991-02-06 | 1996-03-18 | Biotech Australia Pty Ltd | Nematodevaccine |
| US5525508A (en) * | 1991-02-06 | 1996-06-11 | Biotech Australia Pty Limited | Haemonchus contortus vaccine |
| GB9209993D0 (en) * | 1992-05-08 | 1992-06-24 | Munn Edward A | Vaccines |
| ZW8893A1 (en) * | 1992-07-21 | 1994-06-01 | Pitman Moore Inc | Vaccines |
| GB9302302D0 (en) * | 1993-02-05 | 1993-03-24 | Pitman Moore Inc | Process |
| GB9303681D0 (en) * | 1993-02-24 | 1993-04-14 | Pitman Moore Inc | Vaccines |
| GB9322702D0 (en) * | 1993-11-03 | 1993-12-22 | Agricultural & Food Res | Vaccines |
| US5808009A (en) * | 1996-09-23 | 1998-09-15 | North Dakota State University Research Foundation | Method of affinity purifying antibodies |
| US6017757A (en) * | 1997-02-20 | 2000-01-25 | Mississippi State University | Isolated viable nematode intestinal cells |
| US20190069528A1 (en) * | 2016-03-21 | 2019-03-07 | The George Washington University | Engineered human hookworms as a novel biodelivery system for vaccines and biologicals |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2152510B (en) * | 1984-01-10 | 1988-06-15 | Kenneth K Lew | Method for the commercial production of helminths antigens |
| ES8705231A1 (es) * | 1984-11-15 | 1987-05-01 | Biotech Australia Pty Ltd | Un procedimiento para preparar una vacuna anti-helmintica que comprende una suspension, homogeneizado o extracto de una especie de nematodo y un vehiculo farmaceutico. |
| US4761281A (en) * | 1986-04-22 | 1988-08-02 | Immunomed Corporation | Vaccine from Dirofilaria extracts |
| GB8619293D0 (en) * | 1986-08-07 | 1986-09-17 | Munn E A | Anthelmintic agents |
| NZ225295A (en) * | 1987-07-07 | 1991-07-26 | Biotech Australia Pty Ltd | Nematode antigen, its production and vaccines containing it |
| AU618546B2 (en) * | 1987-07-07 | 1992-01-02 | Biotechnology Australia Proprietary Limited | Vaccines against animal parasitic nematodes |
-
1989
- 1989-03-17 GB GB898906156A patent/GB8906156D0/en active Pending
-
1990
- 1990-03-16 ZA ZA902054A patent/ZA902054B/xx unknown
- 1990-03-19 WO PCT/GB1990/000416 patent/WO1990011086A1/en not_active Ceased
- 1990-03-19 CA CA002046601A patent/CA2046601C/en not_active Expired - Fee Related
- 1990-03-19 ES ES90904903T patent/ES2118720T3/es not_active Expired - Lifetime
- 1990-03-19 EP EP97119002A patent/EP0846760A1/en not_active Withdrawn
- 1990-03-19 NZ NZ232984A patent/NZ232984A/en unknown
- 1990-03-19 AU AU52767/90A patent/AU641148B2/en not_active Ceased
- 1990-03-19 CA CA002305966A patent/CA2305966A1/en not_active Abandoned
- 1990-03-19 JP JP02504756A patent/JP3103592B2/ja not_active Expired - Fee Related
- 1990-03-19 DE DE69032323T patent/DE69032323T2/de not_active Expired - Fee Related
- 1990-03-19 AT AT90904903T patent/ATE166231T1/de not_active IP Right Cessation
- 1990-03-19 DK DK90904903T patent/DK0463053T3/da active
- 1990-03-19 EP EP90904903A patent/EP0463053B1/en not_active Expired - Lifetime
-
1991
- 1991-11-18 IN IN853MA1991D patent/IN176658B/en unknown
- 1991-11-18 IN IN853MA1991 patent/IN173646B/en unknown
-
1999
- 1999-08-09 JP JP11225284A patent/JP2000060557A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0463053B1 (en) | 1998-05-20 |
| ZA902054B (en) | 1991-05-29 |
| HK1013951A1 (en) | 1999-09-17 |
| DE69032323T2 (de) | 1998-10-01 |
| EP0846760A1 (en) | 1998-06-10 |
| DE69032323D1 (de) | 1998-06-25 |
| CA2046601A1 (en) | 1990-09-18 |
| CA2046601C (en) | 2000-08-15 |
| IN176658B (es) | 1996-08-17 |
| JP2000060557A (ja) | 2000-02-29 |
| CA2305966A1 (en) | 1990-09-18 |
| EP0463053A1 (en) | 1992-01-02 |
| GB8906156D0 (en) | 1989-05-04 |
| AU5276790A (en) | 1990-10-22 |
| JP3103592B2 (ja) | 2000-10-30 |
| JPH04504118A (ja) | 1992-07-23 |
| DK0463053T3 (da) | 1998-10-07 |
| IN173646B (es) | 1994-06-18 |
| WO1990011086A1 (en) | 1990-10-04 |
| ATE166231T1 (de) | 1998-06-15 |
| NZ232984A (en) | 1994-05-26 |
| AU641148B2 (en) | 1993-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2012809B3 (es) | Derivados del taxol, su preparacion y composiciones farmaceuticas que los contienen. | |
| ES2058185T3 (es) | Derivados de camptotecina y procedimiento para su preparacion. | |
| ES2128362T3 (es) | Fragmentos de proteinas de prion. | |
| SE8700499D0 (sv) | Novel pharmacologically active compounds | |
| ES520985A0 (es) | Procedimiento para la preparacion de nuevos 6,11-dihidrodibenzo (b,e)-tiepin-11-n-alcohilnorescopin-eteres cuaternarios. | |
| ES2076142T3 (es) | Peptidos para el diagnostico de anticuerpos para htlv-iii, su preparacion y uso. | |
| BR9814473A (pt) | Imunógenos anti-retrovirais, preparação e uso | |
| DK614987D0 (da) | Syntetiske htlv-iii peptider, praeparater og anvendelser deraf | |
| ES2057191T5 (es) | Metodo de produccion para una composicion que contiene proteinas. | |
| ES2118720T3 (es) | Produccion y utilizacion de agentes antihelminticos e inmunogenos protectores. | |
| DE69119074D1 (de) | Kovalente-ther lipidnukleosid-konjugate | |
| ES2194836T3 (es) | Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana. | |
| ES2097297T3 (es) | Isoquinolein-5-il-sulfonamidas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen. | |
| ES2134197T3 (es) | Vacunas contra el virus del herpes simplex vp16. | |
| ES2107033T3 (es) | Peptidos bpc, su preparacion y su utilizacion. | |
| ES2038969T3 (es) | Procedimiento para la renaturalizacion de proteinas. | |
| ES2054650T3 (es) | Fenilacetonitrilos basicamente substituidos, su obtencion y medicamentos que los contienen. | |
| CO5170467A1 (es) | Capsulas de eter de celulosa libres de turbiedad y proceso para hacer las mismas | |
| FI88401B (fi) | Foerfarande foer framstaellning av peptider med inverkan pao diures och natriures | |
| EA199800526A1 (ru) | Производные бензимидазола и их применение для лечения вирусных инфекций | |
| AR246310A1 (es) | Procedimiento para la preparacion de la cadena alfa- del receptor de la interleucina 5 humana, o partes del mismo, secuencia del adn, vector y celula hospedante. | |
| ES2145234T3 (es) | Derivados de la diosmetina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| ES2097207T3 (es) | Receptor de poli-ig de sintesis, complejos receptor-anticuerpo, produccion y aplicacion de los mismos. | |
| FI892222A0 (fi) | Peptidalkoholer med antikoagulantverkan. | |
| DK0471718T3 (da) | Paracetamolholdigt farmaceutisk præparat |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 463053 Country of ref document: ES |