NO891711L - Hiv env-kodet peptid som er istand til aa fremkalle hiv-inhiberende antistoffer i pattedyr. - Google Patents

Hiv env-kodet peptid som er istand til aa fremkalle hiv-inhiberende antistoffer i pattedyr.

Info

Publication number
NO891711L
NO891711L NO89891711A NO891711A NO891711L NO 891711 L NO891711 L NO 891711L NO 89891711 A NO89891711 A NO 89891711A NO 891711 A NO891711 A NO 891711A NO 891711 L NO891711 L NO 891711L
Authority
NO
Norway
Prior art keywords
antibodies
inhibitive
mammals
hiv env
injection anti
Prior art date
Application number
NO89891711A
Other languages
English (en)
Other versions
NO891711D0 (no
Inventor
William Robert Kenealy
Stephen Robert Petteway
Paul John Durda
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/324,027 external-priority patent/US5562905A/en
Application filed by Du Pont filed Critical Du Pont
Publication of NO891711D0 publication Critical patent/NO891711D0/no
Publication of NO891711L publication Critical patent/NO891711L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Kjemisk syntetisert peptid av 15 aminosyrer betegnet peptid 1-69, som har sekvensen til aminosyre nummer 308 til 322 (RIQRGPGRAFVTIGK) av det humane immunmangelvirus-1 (HIV-1) IIIB env-kodete protein, ble anvendt for å immun-isere dyr. Peptid 1-69 fremkalte anti-stoffer i immuniserte dyr som blokkerer HIV-proliferasjon og blokkerer Hiv-indusert cellefusjon i cellekultur.
NO89891711A 1988-04-26 1989-04-25 Hiv env-kodet peptid som er istand til aa fremkalle hiv-inhiberende antistoffer i pattedyr. NO891711L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18633388A 1988-04-26 1988-04-26
US07/324,027 US5562905A (en) 1988-04-26 1989-03-20 Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals

Publications (2)

Publication Number Publication Date
NO891711D0 NO891711D0 (no) 1989-04-25
NO891711L true NO891711L (no) 1989-10-27

Family

ID=26881983

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89891711A NO891711L (no) 1988-04-26 1989-04-25 Hiv env-kodet peptid som er istand til aa fremkalle hiv-inhiberende antistoffer i pattedyr.

Country Status (10)

Country Link
EP (1) EP0339504A3 (no)
JP (1) JPH02160800A (no)
AU (1) AU632475B2 (no)
DK (1) DK200189A (no)
FI (1) FI891957A (no)
HU (1) HUT51296A (no)
IL (1) IL90058A0 (no)
NO (1) NO891711L (no)
NZ (1) NZ228869A (no)
PT (1) PT90376B (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69029937T2 (de) * 1989-04-25 1997-05-28 Tanox Biosystems Inc FÜr DIE CO4-BINDENDE DOMÄNE VON HIV SPEZIFISCHE ANTIKÖRPER
JPH05506561A (ja) * 1989-06-05 1993-09-30 レプリゲン・コーポレーション HIV―1 MN gp120のヒトモノクローナル抗体
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
US7041293B1 (en) 1990-04-03 2006-05-09 Genentech, Inc. HIV env antibodies
ATE125157T1 (de) * 1990-04-03 1995-08-15 Genentech Inc Methoden und zusammensetzungen zur impfung gegen hiv.
AU8007991A (en) * 1990-06-29 1992-01-23 Daniel Zagury Methods of inducing immune response to aids virus
JP2989862B2 (ja) * 1990-07-02 1999-12-13 財団法人化学及血清療法研究所 モノクローナル抗体
US5712373A (en) * 1990-07-02 1998-01-27 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute HIV monoclonal antibody specific for the HTLV-IIImn gp120 envelope glycoprotein
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
CA2047073A1 (en) * 1990-07-19 1992-01-20 William J. Leanza Coconjugate vaccines comprising immunogenic protein, hiv related peptides, and anionic moieties
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
IL99077A0 (en) * 1990-08-13 1992-07-15 Merck & Co Inc New embodiments of the hiv principal neutralizing determinant and pharmaceutical compositions containing them
US5627035A (en) * 1990-08-22 1997-05-06 Syntello Vaccine Development Ab Peptides that block human immunodeficiency virus and methods of use thereof
US5346989A (en) * 1990-08-22 1994-09-13 Syntello Vaccine Development Kb Peptides for use in induction of T cell activation against HIV-1
EP0594638A1 (en) * 1991-06-03 1994-05-04 Syntello Vaccine Development Ab Peptides for use in induction of t cell activation against hiv-1
WO1993004090A1 (en) * 1991-08-22 1993-03-04 Nissin Shokuhin Kabushiki Kaisha Hiv immunotherapeutics
US5558865A (en) * 1991-08-22 1996-09-24 Nissin Shokuhin Kabushiki Kaisha HIV immunotherapeutics
CA2124691A1 (en) * 1991-12-02 1993-06-10 Jagannadha K. Sastry Compositions for eliciting cytotoxic t-lymphocyte responses against viruses
CA2084180A1 (en) * 1991-12-11 1993-06-12 Paul P. Hung Expression of specific immunogens using viral antigens
JPH0748276A (ja) * 1992-03-26 1995-02-21 Inmeru:Kk Hiv感染症予防ワクチンおよびその製造法
WO1993019775A1 (en) * 1992-03-31 1993-10-14 Medimmune, Inc. Administration of liposomes containing peptides or proteins including ctl eptitopes of hiv proteins
WO1994008618A1 (en) * 1992-10-13 1994-04-28 Children's Hospital Oral tolerance and immune suppression in the treatment of aids
US5274122A (en) * 1992-10-15 1993-12-28 Merck & Co., Inc. Acidic derivatives of homocysteine thiolactone
US6114143A (en) * 1993-03-11 2000-09-05 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Anti-HIV monoclonal antibody
US6180134B1 (en) 1993-03-23 2001-01-30 Sequus Pharmaceuticals, Inc. Enhanced ciruclation effector composition and method
NZ267838A (en) 1993-06-07 1997-12-19 Genentech Inc Preparation of an hiv gp 120 subunit vaccine involving determining a neutralising epitope in the v2 and/or c4 domains
WO1995010777A1 (en) * 1993-10-15 1995-04-20 Rakowicz Szulczynska Ewa M Detection and treatment of breast and gynecological cancer
US6585979B1 (en) 1996-07-08 2003-07-01 Genentech, Inc. HIV envelope polypeptides and immunogenic composition
ZA975889B (en) * 1996-07-08 1998-02-23 Genentech Inc HIV envelope polypeptides and vaccine.
FR2874612A1 (fr) * 2004-08-27 2006-03-03 Commissariat Energie Atomique Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications
EP2778681A1 (en) * 2013-03-15 2014-09-17 Biomay Ag Method for diagnosing a viral infection

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2571968B1 (fr) * 1984-10-18 1989-03-17 Pasteur Institut Virus purifie des lymphadenopathies et du syndrome d'immuno-depression acquise et antigenes d'enveloppe de ce virus, procede d'obtention de ce virus et de ces antigenes d'enveloppe de ce virus, applications de ce virus ou de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic des susdites affections.
DE3588254T2 (de) * 1984-10-18 2008-06-26 Institut Pasteur GAG-Antigen und dessen Verwendung zum Nachweis von LAV-Infektion, sowie in immunogenen Zusammensetzungen
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
WO1987002775A1 (en) * 1985-10-24 1987-05-07 Southwest Foundation For Biomedical Research Synthetic peptides and use for diagnosis and vaccination for aids and arc
WO1987007616A1 (en) * 1986-06-12 1987-12-17 Biogen N.V. Peptides involved in the pathogenesis of hiv infection
NZ221440A (en) * 1986-08-20 1991-11-26 Genetic Systems Corp Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
JP2520464B2 (ja) * 1987-05-29 1996-07-31 タノツクス・バイオシステムズ・インコーポレーテツド Hiv―1を中和するモノクロ―ナル抗体
JP2569185B2 (ja) * 1988-01-26 1997-01-08 アメリカ合衆国 抗hiv応答を喚起する合成抗原

Also Published As

Publication number Publication date
AU632475B2 (en) 1993-01-07
HUT51296A (en) 1990-04-28
DK200189D0 (da) 1989-04-25
NZ228869A (en) 1992-02-25
FI891957A0 (fi) 1989-04-25
PT90376A (pt) 1989-11-10
FI891957A (fi) 1989-10-27
IL90058A0 (en) 1989-12-15
AU3332089A (en) 1989-11-02
JPH02160800A (ja) 1990-06-20
DK200189A (da) 1989-10-27
PT90376B (pt) 1995-01-31
EP0339504A2 (en) 1989-11-02
NO891711D0 (no) 1989-04-25
EP0339504A3 (en) 1990-09-12

Similar Documents

Publication Publication Date Title
NO891711L (no) Hiv env-kodet peptid som er istand til aa fremkalle hiv-inhiberende antistoffer i pattedyr.
ATE175446T1 (de) Immunogene peptide, antikörper sowie deren verwendungen im zusammenhang mit der cd4- rezeptorbindung
NL300013I1 (nl) Nieuwe protein met TNF-remmende werking en hun ber
DK0561907T3 (da) Proteiner med ændrede epitoper og fremgangsmåder til fremstilling deraf
DE69129803D1 (de) Wasserlösliche peptidanaloguen mit bindungstellen
ES2194836T3 (es) Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana.
DE68927379D1 (de) Plättchen blockierende peptide
DE68925660D1 (de) Peptidfragmente von HIV
DK0491628T3 (da) Lipopeptider inducerende cytotoksiske T-lymfocytter og deres anvendelse som vacciner
DK148085C (da) Dipeptidet pyrglu-his(2,4-dinitrophenyl)-oh og fremgangsmaade til fremstilling af lh-rh og lh-rh-analoge peptider under anvendelse af dette dipeptid
DK0707473T3 (da) Orale farmaceutiske præparater omfattende et protein eller et peptid, et antistof og polymerkugler
ES2185628T3 (es) Procedimiento para preparar proteinas modificadas.
DK0541753T3 (da) Hidtil ukendt hybrid, opløselig og ikke-spaltelig gp160-variant
ES2044928T3 (es) Enzima alfa-amidante en terminal c y procedimiento para la produccion y el uso del mismo.
AU4712993A (en) New peptides, antibodies raised against peptides and means for blocking said antibodies, application as medicaments, pharmaceutical compositions and utilization methods
ATE25984T1 (de) Pharmakologisch aktive peptide.
DK0732339T3 (da) Peptider fra HIV-gag-proteinet, fremstilling og anvendelse deraf
DK0474789T3 (da) Peptid med thiol-beskyttet cystein til anvendelse i immnoassays
DK0426314T3 (da) HIV-relaterede peptider
DE69012989D1 (de) Peptiden von retinblastoma gen produkten und antikoerper dagegen.
DK0540560T3 (da) Ancrod-lignende proteiner, fremstilling og anvendelse deraf
ATE46173T1 (de) Pharmakologisch aktive peptide.
ATE69240T1 (de) Mitogene peptide.
ES2017811A6 (es) Procedimiento de obtencion de una nueva proteina especifica de la gestacion de mamiferos y de anticuerpos policlonales y monoclonales de lamisma, utilizables en el diagnostico precoz de gestacion o de mortalidad embrionaria de mamiferos.
RU93004854A (ru) Пептиды для вакцинации и индукции нейтрализующих антител против вируса иммунодефицита человека