ES2037795T3 - Procedimiento para la preparacion del antigeno hrpii de plasmodium falciparum sge2. - Google Patents

Procedimiento para la preparacion del antigeno hrpii de plasmodium falciparum sge2.

Info

Publication number
ES2037795T3
ES2037795T3 ES198888118043T ES88118043T ES2037795T3 ES 2037795 T3 ES2037795 T3 ES 2037795T3 ES 198888118043 T ES198888118043 T ES 198888118043T ES 88118043 T ES88118043 T ES 88118043T ES 2037795 T3 ES2037795 T3 ES 2037795T3
Authority
ES
Spain
Prior art keywords
plasmodium falciparum
sge2
hrpii
antigen
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888118043T
Other languages
English (en)
Inventor
Dr. Knapp. Bernhard
Erika Dr. Hundt
Burkhard Dr. Enders
Hans Dr. Kupper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Application granted granted Critical
Publication of ES2037795T3 publication Critical patent/ES2037795T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C07K16/205—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855—Proteins from animals other than mammals or birds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE PUEDE AISLAR UN GEL POR SCREENIM DEL BANCO DE GENES A ADN DOS DISTINTOS PLASMODIUM FALCIPARUM SIN ANTISUERO EN UNA PROTEINA 41KD, EN SU CASO POR HIBRIDACION CRUZADA CON EL DNA INSERTO, UNO DE LOS CLONES ASI OBTENIDO, QUE CODIFICA PARA UN ISTIDIN ALAVIN, ESTAS PROTEINAS SON CAUSANTES DE INFECCIONES CON P. PALCIPARUM Y ASI ES UNA PARTE CONOCIDA DE LA VACUNA MALARIA.
ES198888118043T 1987-11-03 1988-10-29 Procedimiento para la preparacion del antigeno hrpii de plasmodium falciparum sge2. Expired - Lifetime ES2037795T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873737238 DE3737238A1 (de) 1987-11-03 1987-11-03 Rekombinantes histidinreiches protein (37 kd antigen) von plasmodium falciparum, seine herstellung und verwendung

Publications (1)

Publication Number Publication Date
ES2037795T3 true ES2037795T3 (es) 1993-07-01

Family

ID=6339664

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888118043T Expired - Lifetime ES2037795T3 (es) 1987-11-03 1988-10-29 Procedimiento para la preparacion del antigeno hrpii de plasmodium falciparum sge2.

Country Status (12)

Country Link
US (1) US5393523A (es)
EP (1) EP0315085B1 (es)
JP (1) JPH01165398A (es)
KR (1) KR970009346B1 (es)
AT (1) ATE83928T1 (es)
AU (1) AU618030B2 (es)
DE (2) DE3737238A1 (es)
DK (1) DK610588A (es)
ES (1) ES2037795T3 (es)
FI (1) FI97479C (es)
GR (1) GR3007476T3 (es)
PT (1) PT88915B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0474891A1 (en) * 1990-09-08 1992-03-18 BEHRINGWERKE Aktiengesellschaft Vectors for expression of malarial antigens on the surface of Salmonella vaccine strains
DE4041836A1 (de) * 1990-12-24 1992-06-25 Behringwerke Ag Protektive plasmodium falciparum hybridproteine, die teilsequenzen der malaria-antigene hrpii und serp enthalten, ihre herstellung und verwendung
AU670108B2 (en) * 1992-09-11 1996-07-04 Becton Dickinson & Company Improved antibodies to plasmodium falciparum
EP1754717A1 (en) 2005-08-19 2007-02-21 Université de Lausanne Antigenic peptides and their use
WO2009097159A1 (en) * 2008-02-02 2009-08-06 Tropical Health Systems Llc A blood purification method and appartus for the treatment of malaria

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3583347D1 (de) * 1984-02-22 1991-08-08 Wellcome Found Klonieren von dna fuer protozoenantigene.
AU5603786A (en) * 1985-04-11 1986-10-16 Walter And Eliza Hall Institute Of Medical Research, The Highly repetitive antigens - sharp-arp-mesa-plasmodium falciparum
US5130416A (en) * 1986-08-13 1992-07-14 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA clone containing a genomic fragment of PfHRP-II gene from plasmodium falciparum
US4721617A (en) * 1986-08-14 1988-01-26 Regents Of The University Of Minnesota Vaccine against lyme disease

Also Published As

Publication number Publication date
FI97479B (fi) 1996-09-13
AU2459088A (en) 1989-05-25
PT88915A (pt) 1988-12-01
AU618030B2 (en) 1991-12-12
KR890008318A (ko) 1989-07-10
FI885023L (fi) 1989-05-04
FI885023A0 (fi) 1988-11-01
JPH01165398A (ja) 1989-06-29
KR970009346B1 (en) 1997-06-10
EP0315085A2 (de) 1989-05-10
EP0315085A3 (en) 1990-05-02
DK610588D0 (da) 1988-11-02
DK610588A (da) 1989-05-04
FI97479C (fi) 1996-12-27
ATE83928T1 (de) 1993-01-15
US5393523A (en) 1995-02-28
GR3007476T3 (es) 1993-07-30
PT88915B (pt) 1993-01-29
DE3877136D1 (de) 1993-02-11
DE3737238A1 (de) 1989-05-18
EP0315085B1 (de) 1992-12-30

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