ES2194012T3 - Epitopo p1a1 y p1a2 de la gpiii a de plaquetas, su preparacion y uso. - Google Patents
Epitopo p1a1 y p1a2 de la gpiii a de plaquetas, su preparacion y uso.Info
- Publication number
- ES2194012T3 ES2194012T3 ES93900656T ES93900656T ES2194012T3 ES 2194012 T3 ES2194012 T3 ES 2194012T3 ES 93900656 T ES93900656 T ES 93900656T ES 93900656 T ES93900656 T ES 93900656T ES 2194012 T3 ES2194012 T3 ES 2194012T3
- Authority
- ES
- Spain
- Prior art keywords
- disclosed
- polypeptides
- those
- epitopo
- gpiii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
- C07K14/70557—Integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
Abstract
SE DESCRIBEN POLIPEPTIDOS Y POLIPEPTIDOS DE FUSION QUE IMITAN INMUNOLOGICAMENTE LOS DETERMINANTES NATIVOS P1A1 Y P1A2 DE PROTEINA DE PLAQUETA GPIIIA. TAMBIEN SE DESCRIBEN SEGMENTOS DE ADN Y MOLECULAS DE ADN RECOMBINADAS QUE CODIFICAN ESTOS POLIPEPTIDOS Y POLIPEPTIDOS DE FUSION Y LOS METODOS PARA EXPRESAR Y USAR ESTOS DETERMINANTES. TAMBIEN SE DESCRIBEN ANTICUERPOS QUE INMUNOREACCIONAN CON UN DETERMINANTE U OTRO, PERO NO CON AMBOS, Y LOS METODOS PARA PREPARAR Y USAR ESTOS ANTICUERPOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/808,457 US5939524A (en) | 1991-12-09 | 1991-12-09 | Platelet GPIII P1A1 and P1A2 epitopes, their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2194012T3 true ES2194012T3 (es) | 2003-11-16 |
Family
ID=25198810
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93900656T Expired - Lifetime ES2194012T3 (es) | 1991-12-09 | 1992-11-24 | Epitopo p1a1 y p1a2 de la gpiii a de plaquetas, su preparacion y uso. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5939524A (es) |
EP (1) | EP0625157B1 (es) |
JP (1) | JP4053084B2 (es) |
AT (1) | ATE233811T1 (es) |
AU (1) | AU680190B2 (es) |
CA (1) | CA2125486C (es) |
DE (1) | DE69232945T2 (es) |
DK (1) | DK0625157T3 (es) |
ES (1) | ES2194012T3 (es) |
PT (1) | PT625157E (es) |
WO (1) | WO1993012127A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7442370B2 (en) * | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Jx日鉱日石エネルギー株式会社 | 潤滑油組成物 |
EP2322205A1 (en) | 2003-04-18 | 2011-05-18 | Biogen Idec MA Inc. | Polymer-conjugated glycosylated neublastin |
GB0315754D0 (en) * | 2003-07-04 | 2003-08-13 | Univ Aberdeen | Pharmaceutical compositions |
CA2577755C (en) * | 2004-08-19 | 2014-05-13 | Biogen Idec Ma Inc. | Neublastin variants |
DE602005022082D1 (de) | 2004-08-19 | 2010-08-12 | Biogen Idec Inc | Rückfaltung von proteinen der transforming-growth-factor-beta-familie |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
ES2450065T3 (es) * | 2006-03-01 | 2014-03-21 | Biogen Idec Ma Inc. | Composiciones y métodos para la administración de proteínas de la familia de ligandos del GDNF |
GB0701048D0 (en) * | 2007-01-18 | 2007-02-28 | Univ Aberdeen | A composition |
TWI445544B (zh) | 2007-05-01 | 2014-07-21 | Biogen Idec Inc | 增進血管形成之組合物及方法 |
WO2009020964A2 (en) * | 2007-08-08 | 2009-02-12 | Biogen Idec Ma Inc. | Anti-neublastin antibodies and uses thereof |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3654090A (en) * | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
NL154598B (nl) * | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
US4016043A (en) * | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
US4356270A (en) * | 1977-11-08 | 1982-10-26 | Genentech, Inc. | Recombinant DNA cloning vehicle |
SE428332B (sv) * | 1979-03-08 | 1983-06-20 | Wallac Oy | Forfarande for fluorescensspektroskopisk bestemning av biologiskt aktivt emne, sasom hapten, antikropp eller antigen |
US4403036A (en) * | 1980-12-02 | 1983-09-06 | University Of Iowa Research Foundation | Genetic reagents for generating plasmids containing multiple copies of DNA segments |
US4416988A (en) * | 1980-12-23 | 1983-11-22 | Harvey Rubin | Detection and isolation of enkephalin mRNA using a synthetic oligodeoxynucleotide |
US4714681A (en) * | 1981-07-01 | 1987-12-22 | The Board Of Reagents, The University Of Texas System Cancer Center | Quadroma cells and trioma cells and methods for the production of same |
US4493795A (en) * | 1983-10-17 | 1985-01-15 | Syntex (U.S.A.) Inc. | Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture |
US4599231A (en) * | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
US4599230A (en) * | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
US4569790A (en) * | 1984-03-28 | 1986-02-11 | Cetus Corporation | Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions |
US4707404A (en) * | 1984-04-03 | 1987-11-17 | Mitsubishi Paper Mills, Ltd. | Thermal transfer recording material |
US4818678A (en) * | 1984-05-04 | 1989-04-04 | Scripps Clinic And Research Foundation | Diagnostic system for the detection of cytomegalovirus |
US4683136A (en) * | 1985-03-06 | 1987-07-28 | Scripps Clinic And Research Foundation | Proteinaceous antigens with conformation-independent and conformation-dependent determinants |
US4631211A (en) * | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4882145A (en) * | 1986-12-09 | 1989-11-21 | Scripps Clinic And Research Foundation | T cell epitopes of the hepatitis B virus nucleocapsid protein |
US4828527A (en) * | 1987-12-04 | 1989-05-09 | Donald Spector | Play character |
EP0452364B1 (en) * | 1988-12-22 | 2002-05-22 | Genentech, Inc. | Method for preparing water soluble polypeptides |
US5091302A (en) * | 1989-04-27 | 1992-02-25 | The Blood Center Of Southeastern Wisconsin, Inc. | Polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic applications thereof |
US5177188A (en) * | 1990-12-03 | 1993-01-05 | The Scripps Research Institute | Methods and compositions for diagnosing chronic immune thrombocytopenic purpura |
-
1991
- 1991-12-09 US US07/808,457 patent/US5939524A/en not_active Expired - Lifetime
-
1992
- 1992-11-24 AU AU32249/93A patent/AU680190B2/en not_active Expired
- 1992-11-24 ES ES93900656T patent/ES2194012T3/es not_active Expired - Lifetime
- 1992-11-24 JP JP51092793A patent/JP4053084B2/ja not_active Expired - Lifetime
- 1992-11-24 DE DE69232945T patent/DE69232945T2/de not_active Expired - Lifetime
- 1992-11-24 PT PT93900656T patent/PT625157E/pt unknown
- 1992-11-24 CA CA002125486A patent/CA2125486C/en not_active Expired - Lifetime
- 1992-11-24 EP EP93900656A patent/EP0625157B1/en not_active Expired - Lifetime
- 1992-11-24 DK DK93900656T patent/DK0625157T3/da active
- 1992-11-24 WO PCT/US1992/010178 patent/WO1993012127A1/en active IP Right Grant
- 1992-11-24 AT AT93900656T patent/ATE233811T1/de active
Also Published As
Publication number | Publication date |
---|---|
AU3224993A (en) | 1993-07-19 |
PT625157E (pt) | 2003-07-31 |
JP4053084B2 (ja) | 2008-02-27 |
ATE233811T1 (de) | 2003-03-15 |
AU680190B2 (en) | 1997-07-24 |
DE69232945T2 (de) | 2003-12-04 |
EP0625157B1 (en) | 2003-03-05 |
DE69232945D1 (de) | 2003-04-10 |
JPH07502121A (ja) | 1995-03-02 |
EP0625157A1 (en) | 1994-11-23 |
CA2125486C (en) | 1999-09-07 |
DK0625157T3 (da) | 2003-06-16 |
US5939524A (en) | 1999-08-17 |
EP0625157A4 (en) | 1995-06-28 |
WO1993012127A1 (en) | 1993-06-24 |
CA2125486A1 (en) | 1993-06-24 |
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