FI953442A0 - Gonadotropiinia sisältäviä pakastekuivattuja pallosia - Google Patents

Gonadotropiinia sisältäviä pakastekuivattuja pallosia

Info

Publication number
FI953442A0
FI953442A0 FI953442A FI953442A FI953442A0 FI 953442 A0 FI953442 A0 FI 953442A0 FI 953442 A FI953442 A FI 953442A FI 953442 A FI953442 A FI 953442A FI 953442 A0 FI953442 A0 FI 953442A0
Authority
FI
Finland
Prior art keywords
pct
freeze
beads containing
dried beads
gonadotropin
Prior art date
Application number
FI953442A
Other languages
English (en)
Swedish (sv)
Other versions
FI953442A (fi
FI112324B (fi
Inventor
Arnold Titus Philip Skrabanja
Herman Vromans
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of FI953442A0 publication Critical patent/FI953442A0/fi
Publication of FI953442A publication Critical patent/FI953442A/fi
Application granted granted Critical
Publication of FI112324B publication Critical patent/FI112324B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
FI953442A 1993-04-28 1995-07-14 Menetelmä gonadotropiinia sisältävän pakastekuivatun pallosen valmistamiseksi FI112324B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP93201215 1993-04-28
EP93201215 1993-04-28
PCT/EP1994/001303 WO1994025005A1 (en) 1993-04-28 1994-04-25 Lyospheres comprising gonadotropin
EP9401303 1994-04-25

Publications (3)

Publication Number Publication Date
FI953442A0 true FI953442A0 (fi) 1995-07-14
FI953442A FI953442A (fi) 1995-07-14
FI112324B FI112324B (fi) 2003-11-28

Family

ID=8213798

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953442A FI112324B (fi) 1993-04-28 1995-07-14 Menetelmä gonadotropiinia sisältävän pakastekuivatun pallosen valmistamiseksi

Country Status (16)

Country Link
US (1) US5656597A (fi)
EP (1) EP0695171B1 (fi)
JP (1) JPH08509483A (fi)
KR (1) KR100334856B1 (fi)
AT (1) ATE146360T1 (fi)
AU (1) AU679986B2 (fi)
CA (1) CA2150251C (fi)
DE (1) DE69401204T2 (fi)
DK (1) DK0695171T3 (fi)
ES (1) ES2098140T3 (fi)
FI (1) FI112324B (fi)
GR (1) GR3022510T3 (fi)
HK (1) HK1002017A1 (fi)
NO (1) NO311168B1 (fi)
NZ (1) NZ265956A (fi)
WO (1) WO1994025005A1 (fi)

Families Citing this family (34)

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IL120202A (en) * 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
GB2329124B (en) * 1997-09-12 2002-05-08 Hiran Asoka Malinga Ratwatte Method of forming dose units of active agents
EP1658840A1 (en) * 1999-04-05 2006-05-24 Mannkind Corporation Methods for fine powder formation
CA2367131C (en) * 1999-04-05 2007-07-03 Solomon S. Steiner Methods for fine powder formation
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
EP1894591B1 (en) 2002-03-20 2013-06-26 MannKind Corporation Cartridge for an inhalation apparatus
US20040248784A1 (en) * 2003-06-03 2004-12-09 Marco Filicori Unitary combinations of FSH and hCG
EP1643972A4 (en) * 2003-06-27 2010-01-20 Smithkline Beecham Corp STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
ES2540853T3 (es) 2004-08-23 2015-07-14 Mannkind Corporation Sales de dicetopiperazina para la administración de fármacos
DK1928423T3 (en) 2005-09-14 2016-02-29 Mannkind Corp A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
TWI436789B (zh) 2008-01-21 2014-05-11 Intervet Int Bv 含有藥學化合物的顆粒之冷凍乾燥方法及含有此顆粒的藥學包
EP2254594B1 (en) 2008-03-05 2015-06-03 Sanofi Pasteur Process for stabilizing an adjuvant containing vaccine composition
CN101269215B (zh) * 2008-05-15 2011-03-23 上海天伟生物制药有限公司 一种糖蛋白激素组合物
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
PL2293833T3 (pl) 2008-06-13 2016-08-31 Mannkind Corp Inhalator proszkowy i układ do dostarczania leku
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
MX359281B (es) 2010-06-21 2018-09-21 Mannkind Corp Sistema y metodos para suministrar un farmaco en polvo seco.
SG194034A1 (en) 2011-04-01 2013-11-29 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
IN2014DN03093A (fi) 2011-10-24 2015-05-15 Mannkind Corp
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
SG10201708090TA (en) 2013-03-15 2017-11-29 Mannkind Corp Microcrystalline diketopiperazine compositions and methods
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
JP6855469B2 (ja) * 2015-10-16 2021-04-07 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 消化器標的療法のための処方物を調製するための工程

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932943A (en) * 1970-08-14 1976-01-20 E. I. Du Pont De Nemours And Company Method of preparation of lyophilized biological products
ATE14047T1 (de) * 1981-12-11 1985-07-15 Wyeth John & Brother Ltd Verfahren und vorrichtung zum gefrieren einer fluessigkeit.
JPS60258125A (ja) * 1984-06-06 1985-12-20 Hayashibara Biochem Lab Inc 蛋白性生理活性物質を含有する水溶性乾燥物
JPH0739339B2 (ja) * 1989-05-01 1995-05-01 アルカーメス コントロールド セラピューティクス，インコーポレイテッド 生物活性を有する分子の小粒子の製造方法
IE64738B1 (en) * 1990-03-20 1995-09-06 Akzo Nv Stabilized gonadotropin containing preparations

Also Published As

Publication number Publication date
JPH08509483A (ja) 1996-10-08
DE69401204D1 (de) 1997-01-30
ES2098140T3 (es) 1997-04-16
GR3022510T3 (en) 1997-05-31
KR950703934A (ko) 1995-11-17
HK1002017A1 (en) 1998-07-24
NO311168B1 (no) 2001-10-22
EP0695171B1 (en) 1996-12-18
DK0695171T3 (da) 1997-06-02
EP0695171A1 (en) 1996-02-07
NO954320D0 (no) 1995-10-27
US5656597A (en) 1997-08-12
ATE146360T1 (de) 1997-01-15
NZ265956A (en) 1996-09-25
KR100334856B1 (ko) 2002-11-07
WO1994025005A1 (en) 1994-11-10
CA2150251C (en) 2005-02-22
AU6648894A (en) 1994-11-21
CA2150251A1 (en) 1994-11-10
AU679986B2 (en) 1997-07-17
NO954320L (no) 1995-10-27
DE69401204T2 (de) 1997-06-05
FI953442A (fi) 1995-07-14
FI112324B (fi) 2003-11-28

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Owner name: N.V. ORGANON

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