ES2124893T3 - Nuevos complejos de inclusion de sales de nimesulida y de ciclodextrina. - Google Patents
Nuevos complejos de inclusion de sales de nimesulida y de ciclodextrina.Info
- Publication number
- ES2124893T3 ES2124893T3 ES94919796T ES94919796T ES2124893T3 ES 2124893 T3 ES2124893 T3 ES 2124893T3 ES 94919796 T ES94919796 T ES 94919796T ES 94919796 T ES94919796 T ES 94919796T ES 2124893 T3 ES2124893 T3 ES 2124893T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- inclusion
- complexes
- cyclodextrin
- nimesulide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Medical Informatics (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
COMPLEJOS DE INCLUSION DE SALES ALCALINOTERROSA Y ALCALI NIMESULIDO DE FORMULA GENERAL (I) DONDE ALCALINOTERROSO Y ALCALI CLODEXTRINA, COMPOSICIONES QUE LOS CONTIENEN, PROCESOS PARA LA PREPARACION DE LOS COMPLEJOS POR LA COMPLEJACION DE SALES DE NIMESULIDO POR COMPLEJACION ASI COMO METODOS PARA USARLAS COMO PRODUCTOS FARMACEUTICOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9301518A HU210922B (en) | 1993-05-24 | 1993-05-24 | Nimesulide alkali salt cyclodextrin inclusion complexes their preparation and pharmaceutical compositions containing them |
PCT/HU1994/000014 WO1994028031A1 (en) | 1993-05-24 | 1994-05-18 | New nimesulide salt cyclodextrin inclusion complexes |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2124893T3 true ES2124893T3 (es) | 1999-02-16 |
Family
ID=10983630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94919796T Expired - Lifetime ES2124893T3 (es) | 1993-05-24 | 1994-05-18 | Nuevos complejos de inclusion de sales de nimesulida y de ciclodextrina. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5744165A (es) |
EP (1) | EP0656015B1 (es) |
JP (1) | JPH07509498A (es) |
KR (1) | KR950702580A (es) |
AT (1) | ATE170194T1 (es) |
AU (1) | AU675146B2 (es) |
CA (1) | CA2140887C (es) |
CZ (1) | CZ285962B6 (es) |
DE (1) | DE69412760T2 (es) |
DK (1) | DK0656015T3 (es) |
ES (1) | ES2124893T3 (es) |
FI (1) | FI950294A0 (es) |
HU (1) | HU210922B (es) |
NO (1) | NO307570B1 (es) |
RU (1) | RU2129564C1 (es) |
SI (1) | SI0656015T1 (es) |
WO (1) | WO1994028031A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU672285B2 (en) * | 1993-02-19 | 1996-09-26 | Taisho Pharmaceutical Co., Ltd. | 5-Aminoacetylaminosulfonanilide compound |
HUP9601442A3 (en) * | 1995-07-25 | 1999-03-29 | Panacea Biotec Ltd | Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them |
UA57734C2 (uk) | 1996-05-07 | 2003-07-15 | Пфайзер Інк. | Комплекси включення арилгетероциклічних солей |
IN186315B (es) * | 1996-12-12 | 2001-08-04 | Panacea Biotec Ltd | |
ES2129010B1 (es) * | 1997-01-02 | 2000-01-16 | Gold Oscar | Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion. |
IT1291895B1 (it) | 1997-04-24 | 1999-01-21 | Errekappa Euroterapici S P A | Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo |
IT1298221B1 (it) * | 1998-02-10 | 1999-12-20 | Helsinn Healthcare Sa | Sali micronizzati di nimesulide |
EP1172101A1 (en) * | 2000-06-20 | 2002-01-16 | Helsinn Healthcare S.A. | The use of nimesulide for the treatment of psoriasis and psoriatic arthritis |
IT1318588B1 (it) * | 2000-06-20 | 2003-08-27 | Helsinn Healthcare Sa | Uso della nimesulide nel trattamento di patologie dermatologiche. |
TWI321054B (en) | 2000-12-19 | 2010-03-01 | California Inst Of Techn | Compositions containing inclusion complexes |
EP2402036B1 (en) | 2002-09-06 | 2018-02-14 | Cerulean Pharma Inc. | Cyclodextrin-based polymers for delivering the therapeutic agents covalently attached thereto |
RU2005114007A (ru) | 2002-10-09 | 2005-10-10 | Инсерт Терапьютикс, Инк. (Us) | Материалы на основе циклодекстринов, их композиции и применение |
CN1511828A (zh) * | 2002-12-31 | 2004-07-14 | �й������ž�����ҽѧ��ѧԺ����ҽ | 磺酰苯胺类衍生物及其医药用途 |
DE102004060914A1 (de) * | 2004-12-17 | 2006-07-06 | Bioghurt Biogarde Gmbh & Co. Kg | Verwendung von Liponsäure-haltigen Cyclodextrin-Komplexen |
US20080176958A1 (en) | 2007-01-24 | 2008-07-24 | Insert Therapeutics, Inc. | Cyclodextrin-based polymers for therapeutics delivery |
WO2014055493A1 (en) | 2012-10-02 | 2014-04-10 | Cerulean Pharma Inc. | Methods and systems for polymer precipitation and generation of particles |
CN109608370A (zh) * | 2019-01-22 | 2019-04-12 | 山西康斯亚森生物科技有限公司 | 尼美舒利衍生物和制备方法及用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5920230A (ja) * | 1982-07-19 | 1984-02-01 | チバ−ガイギ−・アクチエンゲゼルシヤフト | ピルプロフエン含有薬剤 |
GB8813682D0 (en) * | 1988-06-09 | 1988-07-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
IT1248475B (it) * | 1990-05-22 | 1995-01-19 | Angeli Inst Spa | Composti di inclusione di nimesulide con ciclodestrine |
-
1993
- 1993-05-24 HU HU9301518A patent/HU210922B/hu not_active IP Right Cessation
-
1994
- 1994-05-18 AT AT94919796T patent/ATE170194T1/de not_active IP Right Cessation
- 1994-05-18 CZ CZ95163A patent/CZ285962B6/cs not_active IP Right Cessation
- 1994-05-18 US US08/374,765 patent/US5744165A/en not_active Expired - Lifetime
- 1994-05-18 RU RU95105977A patent/RU2129564C1/ru active
- 1994-05-18 CA CA002140887A patent/CA2140887C/en not_active Expired - Fee Related
- 1994-05-18 EP EP94919796A patent/EP0656015B1/en not_active Expired - Lifetime
- 1994-05-18 AU AU70813/94A patent/AU675146B2/en not_active Ceased
- 1994-05-18 DK DK94919796T patent/DK0656015T3/da active
- 1994-05-18 ES ES94919796T patent/ES2124893T3/es not_active Expired - Lifetime
- 1994-05-18 KR KR1019950700275A patent/KR950702580A/ko not_active Application Discontinuation
- 1994-05-18 JP JP7500436A patent/JPH07509498A/ja active Pending
- 1994-05-18 SI SI9430204T patent/SI0656015T1/xx unknown
- 1994-05-18 DE DE69412760T patent/DE69412760T2/de not_active Expired - Fee Related
- 1994-05-18 WO PCT/HU1994/000014 patent/WO1994028031A1/en active IP Right Grant
-
1995
- 1995-01-23 NO NO950243A patent/NO307570B1/no not_active IP Right Cessation
- 1995-01-24 FI FI950294A patent/FI950294A0/fi unknown
Also Published As
Publication number | Publication date |
---|---|
RU95105977A (ru) | 1997-02-10 |
DE69412760D1 (de) | 1998-10-01 |
CA2140887A1 (en) | 1994-12-08 |
ATE170194T1 (de) | 1998-09-15 |
KR950702580A (ko) | 1995-07-29 |
NO950243D0 (no) | 1995-01-23 |
WO1994028031A1 (en) | 1994-12-08 |
FI950294A (fi) | 1995-01-24 |
DE69412760T2 (de) | 1999-05-20 |
US5744165A (en) | 1998-04-28 |
DK0656015T3 (da) | 1999-05-25 |
EP0656015B1 (en) | 1998-08-26 |
HU210922B (en) | 1995-09-28 |
HU9301518D0 (en) | 1993-09-28 |
AU675146B2 (en) | 1997-01-23 |
EP0656015A1 (en) | 1995-06-07 |
FI950294A0 (fi) | 1995-01-24 |
NO950243L (no) | 1995-03-13 |
CZ16395A3 (en) | 1995-10-18 |
JPH07509498A (ja) | 1995-10-19 |
RU2129564C1 (ru) | 1999-04-27 |
HUT68239A (en) | 1995-06-28 |
SI0656015T1 (en) | 1999-02-28 |
CA2140887C (en) | 2000-08-01 |
CZ285962B6 (cs) | 1999-12-15 |
NO307570B1 (no) | 2000-04-25 |
AU7081394A (en) | 1994-12-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA2A | Application withdrawn |
Effective date: 19941028 |
|
FG2A | Definitive protection |
Ref document number: 656015 Country of ref document: ES |