NO307570B1 - Inklusjonskomplekser oppnådd fra nimesulidalkali- og nimesulidjordalkalisalter og cyklodekstriner eller cyklodekstrinderivater, samt farmasøytisk preparat inneholdende nevnte inklusjonskompleks og fremgangsmåte for å fremstille samme - Google Patents

Inklusjonskomplekser oppnådd fra nimesulidalkali- og nimesulidjordalkalisalter og cyklodekstriner eller cyklodekstrinderivater, samt farmasøytisk preparat inneholdende nevnte inklusjonskompleks og fremgangsmåte for å fremstille samme

Info

Publication number
NO307570B1
NO307570B1 NO950243A NO950243A NO307570B1 NO 307570 B1 NO307570 B1 NO 307570B1 NO 950243 A NO950243 A NO 950243A NO 950243 A NO950243 A NO 950243A NO 307570 B1 NO307570 B1 NO 307570B1
Authority
NO
Norway
Prior art keywords
nimesulide
cyclodextrins
alkaline earth
well
inclusion
Prior art date
Application number
NO950243A
Other languages
English (en)
Norwegian (no)
Other versions
NO950243D0 (no
NO950243L (no
Inventor
Joseph Geczy
Original Assignee
Europharmaceuticals Sa
Cyclolab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europharmaceuticals Sa, Cyclolab Ltd filed Critical Europharmaceuticals Sa
Publication of NO950243D0 publication Critical patent/NO950243D0/no
Publication of NO950243L publication Critical patent/NO950243L/no
Publication of NO307570B1 publication Critical patent/NO307570B1/no

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO950243A 1993-05-24 1995-01-23 Inklusjonskomplekser oppnådd fra nimesulidalkali- og nimesulidjordalkalisalter og cyklodekstriner eller cyklodekstrinderivater, samt farmasøytisk preparat inneholdende nevnte inklusjonskompleks og fremgangsmåte for å fremstille samme NO307570B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9301518A HU210922B (en) 1993-05-24 1993-05-24 Nimesulide alkali salt cyclodextrin inclusion complexes their preparation and pharmaceutical compositions containing them
PCT/HU1994/000014 WO1994028031A1 (en) 1993-05-24 1994-05-18 New nimesulide salt cyclodextrin inclusion complexes

Publications (3)

Publication Number Publication Date
NO950243D0 NO950243D0 (no) 1995-01-23
NO950243L NO950243L (no) 1995-03-13
NO307570B1 true NO307570B1 (no) 2000-04-25

Family

ID=10983630

Family Applications (1)

Application Number Title Priority Date Filing Date
NO950243A NO307570B1 (no) 1993-05-24 1995-01-23 Inklusjonskomplekser oppnådd fra nimesulidalkali- og nimesulidjordalkalisalter og cyklodekstriner eller cyklodekstrinderivater, samt farmasøytisk preparat inneholdende nevnte inklusjonskompleks og fremgangsmåte for å fremstille samme

Country Status (17)

Country Link
US (1) US5744165A (es)
EP (1) EP0656015B1 (es)
JP (1) JPH07509498A (es)
KR (1) KR950702580A (es)
AT (1) ATE170194T1 (es)
AU (1) AU675146B2 (es)
CA (1) CA2140887C (es)
CZ (1) CZ285962B6 (es)
DE (1) DE69412760T2 (es)
DK (1) DK0656015T3 (es)
ES (1) ES2124893T3 (es)
FI (1) FI950294A0 (es)
HU (1) HU210922B (es)
NO (1) NO307570B1 (es)
RU (1) RU2129564C1 (es)
SI (1) SI0656015T1 (es)
WO (1) WO1994028031A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994019318A1 (en) * 1993-02-19 1994-09-01 Taisho Pharmaceutical Co., Ltd. 5-aminoacetylaminosulfonanilide compound
HUP9601442A3 (en) * 1995-07-25 1999-03-29 Panacea Biotec Ltd Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them
UA57734C2 (uk) 1996-05-07 2003-07-15 Пфайзер Інк. Комплекси включення арилгетероциклічних солей
IN186315B (es) * 1996-12-12 2001-08-04 Panacea Biotec Ltd
ES2129010B1 (es) * 1997-01-02 2000-01-16 Gold Oscar Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion.
IT1291895B1 (it) 1997-04-24 1999-01-21 Errekappa Euroterapici S P A Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo
IT1298221B1 (it) * 1998-02-10 1999-12-20 Helsinn Healthcare Sa Sali micronizzati di nimesulide
EP1172101A1 (en) * 2000-06-20 2002-01-16 Helsinn Healthcare S.A. The use of nimesulide for the treatment of psoriasis and psoriatic arthritis
IT1318588B1 (it) * 2000-06-20 2003-08-27 Helsinn Healthcare Sa Uso della nimesulide nel trattamento di patologie dermatologiche.
TWI321054B (en) 2000-12-19 2010-03-01 California Inst Of Techn Compositions containing inclusion complexes
CN102516417B (zh) 2002-09-06 2014-12-10 天蓝制药公司 用于传递治疗剂的以环糊精为基础的聚合物
WO2004032862A2 (en) 2002-10-09 2004-04-22 Insert Therapeutics, Inc. Cyclodextrin-based materials, compositions and uses related thereto
CN1511828A (zh) * 2002-12-31 2004-07-14 �й������ž�����ҽѧ��ѧԺ����ҽ 磺酰苯胺类衍生物及其医药用途
DE102004060914A1 (de) * 2004-12-17 2006-07-06 Bioghurt Biogarde Gmbh & Co. Kg Verwendung von Liponsäure-haltigen Cyclodextrin-Komplexen
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
CN109608370A (zh) * 2019-01-22 2019-04-12 山西康斯亚森生物科技有限公司 尼美舒利衍生物和制备方法及用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
GB8813682D0 (en) * 1988-06-09 1988-07-13 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
IT1248475B (it) * 1990-05-22 1995-01-19 Angeli Inst Spa Composti di inclusione di nimesulide con ciclodestrine

Also Published As

Publication number Publication date
CA2140887C (en) 2000-08-01
ES2124893T3 (es) 1999-02-16
HU9301518D0 (en) 1993-09-28
AU7081394A (en) 1994-12-20
FI950294A (fi) 1995-01-24
DE69412760D1 (de) 1998-10-01
CZ16395A3 (en) 1995-10-18
US5744165A (en) 1998-04-28
RU2129564C1 (ru) 1999-04-27
KR950702580A (ko) 1995-07-29
DE69412760T2 (de) 1999-05-20
DK0656015T3 (da) 1999-05-25
WO1994028031A1 (en) 1994-12-08
CA2140887A1 (en) 1994-12-08
HU210922B (en) 1995-09-28
FI950294A0 (fi) 1995-01-24
HUT68239A (en) 1995-06-28
NO950243D0 (no) 1995-01-23
SI0656015T1 (en) 1999-02-28
JPH07509498A (ja) 1995-10-19
NO950243L (no) 1995-03-13
ATE170194T1 (de) 1998-09-15
EP0656015B1 (en) 1998-08-26
CZ285962B6 (cs) 1999-12-15
EP0656015A1 (en) 1995-06-07
RU95105977A (ru) 1997-02-10
AU675146B2 (en) 1997-01-23

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