DK0695171T3 - Lyosfærer indeholdende gonadotropin - Google Patents

Lyosfærer indeholdende gonadotropin

Info

Publication number
DK0695171T3
DK0695171T3 DK94915121.1T DK94915121T DK0695171T3 DK 0695171 T3 DK0695171 T3 DK 0695171T3 DK 94915121 T DK94915121 T DK 94915121T DK 0695171 T3 DK0695171 T3 DK 0695171T3
Authority
DK
Denmark
Prior art keywords
pct
lyospheres
gonadotropin
sec
date
Prior art date
Application number
DK94915121.1T
Other languages
English (en)
Inventor
Arnold Titus Philip Skrabanja
Herman Vromans
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK0695171T3 publication Critical patent/DK0695171T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
DK94915121.1T 1993-04-28 1994-04-25 Lyosfærer indeholdende gonadotropin DK0695171T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93201215 1993-04-28

Publications (1)

Publication Number Publication Date
DK0695171T3 true DK0695171T3 (da) 1997-06-02

Family

ID=8213798

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94915121.1T DK0695171T3 (da) 1993-04-28 1994-04-25 Lyosfærer indeholdende gonadotropin

Country Status (16)

Country Link
US (1) US5656597A (da)
EP (1) EP0695171B1 (da)
JP (1) JPH08509483A (da)
KR (1) KR100334856B1 (da)
AT (1) ATE146360T1 (da)
AU (1) AU679986B2 (da)
CA (1) CA2150251C (da)
DE (1) DE69401204T2 (da)
DK (1) DK0695171T3 (da)
ES (1) ES2098140T3 (da)
FI (1) FI112324B (da)
GR (1) GR3022510T3 (da)
HK (1) HK1002017A1 (da)
NO (1) NO311168B1 (da)
NZ (1) NZ265956A (da)
WO (1) WO1994025005A1 (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL120202A (en) * 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
GB2329124B (en) * 1997-09-12 2002-05-08 Hiran Asoka Malinga Ratwatte Method of forming dose units of active agents
EP1658840A1 (en) * 1999-04-05 2006-05-24 Mannkind Corporation Methods for fine powder formation
CA2367131C (en) 1999-04-05 2007-07-03 Solomon S. Steiner Methods for fine powder formation
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
US20040248784A1 (en) * 2003-06-03 2004-12-09 Marco Filicori Unitary combinations of FSH and hCG
WO2005002546A1 (en) * 2003-06-27 2005-01-13 Smithkline Beecham Corporation Stabilized topotecan liposomal composition and methods
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2322180B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Diketopiperazine salts for drug delivery
RU2390325C2 (ru) 2005-09-14 2010-05-27 Маннкайнд Корпорейшн Способ приготовления лекарственного препарата, основанный на увеличении сродства активных агентов к поверхностям кристаллических микрочастиц
RU2403059C2 (ru) 2006-02-22 2010-11-10 Маннкайнд Корпорейшн Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент
TWI436789B (zh) 2008-01-21 2014-05-11 Intervet Int Bv 含有藥學化合物的顆粒之冷凍乾燥方法及含有此顆粒的藥學包
MX2010008799A (es) 2008-03-05 2010-09-07 Sanofi Pasteur Proceso para estabilizar una composicion de vacuna que contiene adyuvante.
CN101269215B (zh) * 2008-05-15 2011-03-23 上海天伟生物制药有限公司 一种糖蛋白激素组合物
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
US8636001B2 (en) 2008-06-13 2014-01-28 Mannkind Corporation Dry powder inhaler and system for drug delivery
DK2609954T3 (da) 2008-06-20 2022-02-14 Mannkind Corp Interaktivt apparat til realtidsafbildning af inhalationspræstationer
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
CN102647979B (zh) 2009-06-12 2015-03-04 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
EP2582421A1 (en) 2010-06-21 2013-04-24 MannKind Corporation Dry powder drug delivery system and methods
WO2012135765A2 (en) 2011-04-01 2012-10-04 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CN103945859A (zh) 2011-10-24 2014-07-23 曼金德公司 用于治疗疼痛的方法和组合物
US9802012B2 (en) 2012-07-12 2017-10-31 Mannkind Corporation Dry powder drug delivery system and methods
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
SG11201507564PA (en) 2013-03-15 2015-10-29 Mannkind Corp Microcrystalline diketopiperazine compositions and methods
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3362052A4 (en) * 2015-10-16 2019-06-19 Merck Sharp & Dohme Corp. PROCESS FOR PREPARING FORMULATIONS FOR GASTROINTESTINAL THERAPIES

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932943A (en) * 1970-08-14 1976-01-20 E. I. Du Pont De Nemours And Company Method of preparation of lyophilized biological products
DE3264450D1 (en) * 1981-12-11 1985-08-01 Wyeth John & Brother Ltd Process and apparatus for freezing a liquid medium
JPS60258125A (ja) * 1984-06-06 1985-12-20 Hayashibara Biochem Lab Inc 蛋白性生理活性物質を含有する水溶性乾燥物
JPH0739339B2 (ja) * 1989-05-01 1995-05-01 アルカーメス コントロールド セラピューティクス，インコーポレイテッド 生物活性を有する分子の小粒子の製造方法
IE64738B1 (en) * 1990-03-20 1995-09-06 Akzo Nv Stabilized gonadotropin containing preparations

Also Published As

Publication number Publication date
ES2098140T3 (es) 1997-04-16
AU6648894A (en) 1994-11-21
FI953442A (fi) 1995-07-14
ATE146360T1 (de) 1997-01-15
NZ265956A (en) 1996-09-25
KR100334856B1 (ko) 2002-11-07
WO1994025005A1 (en) 1994-11-10
DE69401204T2 (de) 1997-06-05
FI112324B (fi) 2003-11-28
CA2150251A1 (en) 1994-11-10
EP0695171A1 (en) 1996-02-07
CA2150251C (en) 2005-02-22
DE69401204D1 (de) 1997-01-30
HK1002017A1 (en) 1998-07-24
JPH08509483A (ja) 1996-10-08
AU679986B2 (en) 1997-07-17
NO954320L (no) 1995-10-27
FI953442A0 (fi) 1995-07-14
US5656597A (en) 1997-08-12
NO311168B1 (no) 2001-10-22
GR3022510T3 (en) 1997-05-31
KR950703934A (ko) 1995-11-17
NO954320D0 (no) 1995-10-27
EP0695171B1 (en) 1996-12-18

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