ATE146360T1 - Gonadotropin enthaltende gefriergetrocknete troepfen - Google Patents
Gonadotropin enthaltende gefriergetrocknete troepfenInfo
- Publication number
- ATE146360T1 ATE146360T1 AT94915121T AT94915121T ATE146360T1 AT E146360 T1 ATE146360 T1 AT E146360T1 AT 94915121 T AT94915121 T AT 94915121T AT 94915121 T AT94915121 T AT 94915121T AT E146360 T1 ATE146360 T1 AT E146360T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- freeze
- drops containing
- gonadotropin
- dried drops
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93201215 | 1993-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE146360T1 true ATE146360T1 (de) | 1997-01-15 |
Family
ID=8213798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94915121T ATE146360T1 (de) | 1993-04-28 | 1994-04-25 | Gonadotropin enthaltende gefriergetrocknete troepfen |
Country Status (16)
Country | Link |
---|---|
US (1) | US5656597A (de) |
EP (1) | EP0695171B1 (de) |
JP (1) | JPH08509483A (de) |
KR (1) | KR100334856B1 (de) |
AT (1) | ATE146360T1 (de) |
AU (1) | AU679986B2 (de) |
CA (1) | CA2150251C (de) |
DE (1) | DE69401204T2 (de) |
DK (1) | DK0695171T3 (de) |
ES (1) | ES2098140T3 (de) |
FI (1) | FI112324B (de) |
GR (1) | GR3022510T3 (de) |
HK (1) | HK1002017A1 (de) |
NO (1) | NO311168B1 (de) |
NZ (1) | NZ265956A (de) |
WO (1) | WO1994025005A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL120202A (en) * | 1996-03-07 | 2001-03-19 | Akzo Nobel Nv | Container with freeze-dried vaccine components |
GB2329124B (en) * | 1997-09-12 | 2002-05-08 | Hiran Asoka Malinga Ratwatte | Method of forming dose units of active agents |
EP1658840A1 (de) * | 1999-04-05 | 2006-05-24 | Mannkind Corporation | Verfahren zur Bildung von feinem Pulver |
AU773556B2 (en) * | 1999-04-05 | 2004-05-27 | Mannkind Corporation | Methods for fine powder formation |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
SI1494732T1 (sl) | 2002-03-20 | 2008-08-31 | Mannking Corp | Inhalacijski aparat |
US20040248784A1 (en) * | 2003-06-03 | 2004-12-09 | Marco Filicori | Unitary combinations of FSH and hCG |
EP1643972A4 (de) * | 2003-06-27 | 2010-01-20 | Smithkline Beecham Corp | Stabilisierte liposomale topotecan-zusammensetzung und verfahren |
ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
US7820676B2 (en) | 2004-08-23 | 2010-10-26 | Mannkind Corporation | Diketopiperazine salts for drug delivery and related methods |
CA2621806C (en) | 2005-09-14 | 2016-08-02 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents |
RU2403059C2 (ru) | 2006-02-22 | 2010-11-10 | Маннкайнд Корпорейшн | Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент |
TWI436789B (zh) | 2008-01-21 | 2014-05-11 | Intervet Int Bv | 含有藥學化合物的顆粒之冷凍乾燥方法及含有此顆粒的藥學包 |
MX2010008799A (es) | 2008-03-05 | 2010-09-07 | Sanofi Pasteur | Proceso para estabilizar una composicion de vacuna que contiene adyuvante. |
CN101269215B (zh) * | 2008-05-15 | 2011-03-23 | 上海天伟生物制药有限公司 | 一种糖蛋白激素组合物 |
CA3086027C (en) | 2008-06-13 | 2022-05-17 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
RU2470681C2 (ru) | 2008-06-20 | 2012-12-27 | Маннкайнд Корпорейшн | Интерактивное устройство и способ профилирования усилий при ингаляции в реальном масштабе времени |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
EP2676695A3 (de) | 2009-03-11 | 2017-03-01 | MannKind Corporation | Vorrichtung, System und Verfahren zur Messung des Widerstandes eines Inhalators |
KR20210027546A (ko) | 2009-06-12 | 2021-03-10 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
EP2694402B1 (de) | 2011-04-01 | 2017-03-22 | MannKind Corporation | Blisterverpackung für pharmakartuschen |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
CN103945859A (zh) | 2011-10-24 | 2014-07-23 | 曼金德公司 | 用于治疗疼痛的方法和组合物 |
CN104619369B (zh) | 2012-07-12 | 2018-01-30 | 曼金德公司 | 干粉药物输送系统和方法 |
US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
JP6523247B2 (ja) | 2013-03-15 | 2019-05-29 | マンカインド コーポレイション | 微結晶性ジケトピペラジン粒子の製造方法および乾燥粉末組成物の製造方法 |
WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
WO2017066134A1 (en) * | 2015-10-16 | 2017-04-20 | Merck Sharp & Dohme Corp. | Processes for preparing formulations for gastrointestinal-targeted therapies |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3932943A (en) * | 1970-08-14 | 1976-01-20 | E. I. Du Pont De Nemours And Company | Method of preparation of lyophilized biological products |
DE3264450D1 (en) * | 1981-12-11 | 1985-08-01 | Wyeth John & Brother Ltd | Process and apparatus for freezing a liquid medium |
JPS60258125A (ja) * | 1984-06-06 | 1985-12-20 | Hayashibara Biochem Lab Inc | 蛋白性生理活性物質を含有する水溶性乾燥物 |
ES2062530T3 (es) * | 1989-05-01 | 1994-12-16 | Alkermes Inc | Procedimiento para producir particulas pequeñas de moleculas biologicamente activas. |
IE64738B1 (en) * | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
-
1994
- 1994-04-25 NZ NZ265956A patent/NZ265956A/en not_active IP Right Cessation
- 1994-04-25 US US08/454,333 patent/US5656597A/en not_active Expired - Lifetime
- 1994-04-25 JP JP6523868A patent/JPH08509483A/ja active Pending
- 1994-04-25 KR KR1019950702180A patent/KR100334856B1/ko not_active IP Right Cessation
- 1994-04-25 AT AT94915121T patent/ATE146360T1/de active
- 1994-04-25 EP EP94915121A patent/EP0695171B1/de not_active Expired - Lifetime
- 1994-04-25 DE DE69401204T patent/DE69401204T2/de not_active Expired - Lifetime
- 1994-04-25 CA CA002150251A patent/CA2150251C/en not_active Expired - Fee Related
- 1994-04-25 WO PCT/EP1994/001303 patent/WO1994025005A1/en active IP Right Grant
- 1994-04-25 AU AU66488/94A patent/AU679986B2/en not_active Ceased
- 1994-04-25 ES ES94915121T patent/ES2098140T3/es not_active Expired - Lifetime
- 1994-04-25 DK DK94915121.1T patent/DK0695171T3/da active
-
1995
- 1995-07-14 FI FI953442A patent/FI112324B/fi not_active IP Right Cessation
- 1995-10-27 NO NO19954320A patent/NO311168B1/no not_active IP Right Cessation
-
1997
- 1997-02-11 GR GR970400207T patent/GR3022510T3/el unknown
-
1998
- 1998-02-11 HK HK98101026A patent/HK1002017A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH08509483A (ja) | 1996-10-08 |
EP0695171B1 (de) | 1996-12-18 |
HK1002017A1 (en) | 1998-07-24 |
WO1994025005A1 (en) | 1994-11-10 |
DK0695171T3 (da) | 1997-06-02 |
DE69401204T2 (de) | 1997-06-05 |
KR950703934A (ko) | 1995-11-17 |
ES2098140T3 (es) | 1997-04-16 |
CA2150251A1 (en) | 1994-11-10 |
NO954320D0 (no) | 1995-10-27 |
FI953442A0 (fi) | 1995-07-14 |
CA2150251C (en) | 2005-02-22 |
FI112324B (fi) | 2003-11-28 |
DE69401204D1 (de) | 1997-01-30 |
AU679986B2 (en) | 1997-07-17 |
US5656597A (en) | 1997-08-12 |
FI953442A (fi) | 1995-07-14 |
AU6648894A (en) | 1994-11-21 |
NZ265956A (en) | 1996-09-25 |
NO954320L (no) | 1995-10-27 |
GR3022510T3 (en) | 1997-05-31 |
EP0695171A1 (de) | 1996-02-07 |
NO311168B1 (no) | 2001-10-22 |
KR100334856B1 (ko) | 2002-11-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |