ES2148458T3 - Derivados de fenil-4-tiazoles sustituidos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Derivados de fenil-4-tiazoles sustituidos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2148458T3
ES2148458T3 ES95402969T ES95402969T ES2148458T3 ES 2148458 T3 ES2148458 T3 ES 2148458T3 ES 95402969 T ES95402969 T ES 95402969T ES 95402969 T ES95402969 T ES 95402969T ES 2148458 T3 ES2148458 T3 ES 2148458T3
Authority
ES
Spain
Prior art keywords
fenil
derivatives
procedure
contain
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95402969T
Other languages
English (en)
Inventor
Alain Badorc
Marie-Francoise Bordes
Cointet Paul De
Jean-Marc Herbert
Jean-Pierre Maffrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Application granted granted Critical
Publication of ES2148458T3 publication Critical patent/ES2148458T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A COMPUESTOS DE FORMULA (I) EN LA QUE R, A, R{SUB,1} Y Y SON TALES COMO SE DEFINEN EN LA REIVINDICACION 1.
ES95402969T 1994-12-28 1995-12-28 Derivados de fenil-4-tiazoles sustituidos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2148458T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9415805A FR2728901B1 (fr) 1994-12-28 1994-12-28 Derives de phenyl-4-thiazoles substitues, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ES2148458T3 true ES2148458T3 (es) 2000-10-16

Family

ID=9470360

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95402969T Expired - Lifetime ES2148458T3 (es) 1994-12-28 1995-12-28 Derivados de fenil-4-tiazoles sustituidos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Country Status (28)

Country Link
US (1) US5607952A (es)
EP (1) EP0719775B1 (es)
JP (1) JP3027110B2 (es)
KR (1) KR960022515A (es)
CN (1) CN1048726C (es)
AR (1) AR002017A1 (es)
AT (1) ATE194616T1 (es)
AU (1) AU703490B2 (es)
BR (1) BR1100524A (es)
CA (1) CA2166165A1 (es)
CZ (1) CZ346595A3 (es)
DE (1) DE69517936T2 (es)
DK (1) DK0719775T3 (es)
ES (1) ES2148458T3 (es)
FI (1) FI956278A7 (es)
FR (1) FR2728901B1 (es)
GR (1) GR3034582T3 (es)
HU (1) HUT75096A (es)
IL (1) IL116560A (es)
NO (1) NO306114B1 (es)
NZ (1) NZ280720A (es)
PL (1) PL312078A1 (es)
PT (1) PT719775E (es)
RU (1) RU2124515C1 (es)
SI (1) SI0719775T1 (es)
SK (1) SK281247B6 (es)
TW (1) TW418207B (es)
ZA (1) ZA9511029B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840733A (en) * 1996-07-01 1998-11-24 Redcell, Canada, Inc. Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes
US6010911A (en) * 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
FR2764511B1 (fr) * 1997-06-13 2000-09-08 Sanofi Sa Compositions pour le traitement et la prevention de la thrombose arterielle et utilisation d'un inhibiteur du facteur xa seul et/ou en combinaison avec un antiagregant plaquettaire
WO2000029406A2 (en) 1998-11-18 2000-05-25 Du Pont Pharmaceuticals Company Novel isoxazoline fibrinogen receptor antagonists
US6319937B1 (en) * 1998-11-18 2001-11-20 Dupont Pharmaceuticals Company Isoxazoline fibrinogen receptor antagonists
FR2797400A1 (fr) * 1999-08-11 2001-02-16 Sanofi Synthelabo Associations a activite anti-thrombotique constituees de l'hydrogenosulfate de clopidogrel et d'un antagoniste des recepteurs gpiib/iiia et les compositions pharmaceutiques les contenant
TWI284639B (en) * 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
US20060198836A1 (en) * 2003-07-17 2006-09-07 Smithkline Beecham Corporation Method of treating hit patients with argatroban
CN103130739B (zh) * 2003-08-12 2015-09-16 盐野义制药株式会社 具有血小板生成素受体激动作用的化合物
WO2005014593A1 (en) * 2003-08-12 2005-02-17 F. Hoffmann-La Roche Ag Thiazole derivatives as npy antagonists
CN101068570A (zh) * 2004-05-13 2007-11-07 贝林格尔·英格海姆国际有限公司 双嘧达莫治疗血小板抑制剂的抗药性的用途
ATE532058T1 (de) 2004-05-17 2011-11-15 Medtronic Inc Point-of-care-heparinbestimmungssystem
US7423053B2 (en) * 2004-07-15 2008-09-09 Hoffmann-La Roche Inc. 4-Aminothiazole derivatives
AU2005272389B2 (en) * 2004-08-11 2011-08-04 Kyorin Pharmaceutical Co., Ltd. Novel cyclic aminobenzoic acid derivative
JP5114395B2 (ja) * 2005-06-30 2013-01-09 プロシディオン・リミテッド Ｇｐｃｒアゴニスト
RU2373929C1 (ru) * 2008-11-11 2009-11-27 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО БГМУ РОСЗДРАВА) Корректор системы гемостаза, проявляющий ингибирующее действие на адгезивно-агрегационную функцию тромбоцитов для профилактики патологического тромбообразования

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB542363A (en) * 1940-07-03 1942-01-06 Joseph Arthur Musgrave Woodcoc Improvements in or relating to the manufacture of graphite electrodes
DK157135C (da) * 1982-04-07 1990-04-02 Pfizer Analogifremgangsmaade til fremstilling af 1,2,4-triazol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf
DE3839758A1 (de) * 1988-10-24 1990-04-26 Bayer Ag Substituierte 2-aminothiazole
US5231091A (en) * 1988-12-19 1993-07-27 American Cyanamid Company Bis-arylphosphate ester antagonists of platelet activating factor
FR2656610B1 (fr) * 1989-12-29 1992-05-07 Sanofi Sa Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique.
WO1993010091A2 (en) * 1991-11-14 1993-05-27 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
US5405848A (en) * 1993-12-22 1995-04-11 Ortho Pharmaceutical Corporation Substituted thiazolylaminotetrahydropyridopyrimidines derivatives useful as platelet aggregation inhibitors

Also Published As

Publication number Publication date
FI956278L (fi) 1996-06-29
CZ346595A3 (en) 1996-08-14
CN1048726C (zh) 2000-01-26
ATE194616T1 (de) 2000-07-15
SK281247B6 (sk) 2001-01-18
NZ280720A (en) 1997-10-24
FR2728901A1 (fr) 1996-07-05
FI956278A7 (fi) 1996-06-29
SI0719775T1 (en) 2000-12-31
NO955320D0 (no) 1995-12-27
BR1100524A (pt) 2000-03-14
HUT75096A (en) 1997-04-28
DK0719775T3 (da) 2000-10-23
KR960022515A (ko) 1996-07-18
CA2166165A1 (en) 1996-06-29
EP0719775B1 (fr) 2000-07-12
CN1133289A (zh) 1996-10-16
NO306114B1 (no) 1999-09-20
PT719775E (pt) 2000-12-29
HU9503801D0 (en) 1996-02-28
DE69517936D1 (de) 2000-08-17
JPH08231542A (ja) 1996-09-10
IL116560A (en) 2001-03-19
GR3034582T3 (en) 2001-01-31
AU703490B2 (en) 1999-03-25
EP0719775A1 (fr) 1996-07-03
IL116560A0 (en) 1996-03-31
PL312078A1 (en) 1996-07-08
TW418207B (en) 2001-01-11
ZA9511029B (en) 1997-06-30
FR2728901B1 (fr) 1997-03-28
RU2124515C1 (ru) 1999-01-10
FI956278A0 (fi) 1995-12-27
JP3027110B2 (ja) 2000-03-27
AR002017A1 (es) 1998-01-07
US5607952A (en) 1997-03-04
SK163395A3 (en) 1996-09-04
AU4070995A (en) 1996-07-04
NO955320L (no) 1996-07-01
DE69517936T2 (de) 2001-04-19

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