CN1227554A - 取代的6,5-杂二环衍生物 - Google Patents
取代的6,5-杂二环衍生物 Download PDFInfo
- Publication number
- CN1227554A CN1227554A CN97197027A CN97197027A CN1227554A CN 1227554 A CN1227554 A CN 1227554A CN 97197027 A CN97197027 A CN 97197027A CN 97197027 A CN97197027 A CN 97197027A CN 1227554 A CN1227554 A CN 1227554A
- Authority
- CN
- China
- Prior art keywords
- alkyl
- compound
- phenyl
- ethyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 0 BC1=C*C(*)=*CCc2c1[s]c(*)c2* Chemical compound BC1=C*C(*)=*CCc2c1[s]c(*)c2* 0.000 description 6
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C07D487/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Psychology (AREA)
- Oncology (AREA)
- Pregnancy & Childbirth (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2503996P | 1996-08-28 | 1996-08-28 | |
| US60/025,039 | 1996-08-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1227554A true CN1227554A (zh) | 1999-09-01 |
Family
ID=21823717
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97197027A Pending CN1227554A (zh) | 1996-08-28 | 1997-07-25 | 取代的6,5-杂二环衍生物 |
Country Status (36)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100447141C (zh) * | 2001-07-17 | 2008-12-31 | 葛兰素集团有限公司 | 杂双环crf拮抗剂 |
| CN102933584A (zh) * | 2010-04-16 | 2013-02-13 | Abbvie公司 | 激酶的吡咯并吡嗪酮抑制剂 |
| CN102947302A (zh) * | 2010-02-18 | 2013-02-27 | 西班牙国家癌症研究中心 | 三唑并[4,5-b]吡啶衍生物 |
| CN104411314A (zh) * | 2012-07-09 | 2015-03-11 | 詹森药业有限公司 | 磷酸二酯酶10的抑制剂 |
Families Citing this family (148)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10506126A (ja) | 1995-05-12 | 1998-06-16 | ニューロゲン コーポレイション | 新規なデアザプリン誘導体;crf1特異性リガンドの新規なクラス |
| US6313124B1 (en) | 1997-07-23 | 2001-11-06 | Dupont Pharmaceuticals Company | Tetrazine bicyclic compounds |
| US6124289A (en) * | 1996-07-24 | 2000-09-26 | Dupont Pharmaceuticals Co. | Azolo triazines and pyrimidines |
| US6191131B1 (en) | 1997-07-23 | 2001-02-20 | Dupont Pharmaceuticals Company | Azolo triazines and pyrimidines |
| US6060478A (en) * | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
| US7094782B1 (en) | 1996-07-24 | 2006-08-22 | Bristol-Myers Squibb Company | Azolo triazines and pyrimidines |
| JP2001511813A (ja) | 1997-02-18 | 2001-08-14 | ニューロクライン バイオサイエンシーズ,インコーポレイテッド | Crfレセプターアンタゴニストおよびそれらに関連する方法 |
| NZ335823A (en) | 1997-04-22 | 2001-06-29 | Neurocrine Biosciences Inc | Thiophenopyridines, preparation as CRF receptor antagonists |
| JP2002507996A (ja) * | 1997-07-03 | 2002-03-12 | デュポン ファーマシューティカルズ カンパニー | 神経学的障害を治療するためのイミダゾピリミジン類およびイミダゾピリジン類 |
| IL137019A0 (en) * | 1998-01-28 | 2001-06-14 | Du Pont Pharm Co | Azolo triazines and pyrimidines |
| US6187777B1 (en) * | 1998-02-06 | 2001-02-13 | Amgen Inc. | Compounds and methods which modulate feeding behavior and related diseases |
| EP1068205A1 (en) | 1998-04-02 | 2001-01-17 | Neurogen Corporation | Aminoalkyl substituted 5,6,7,8-tetrahydro-9h pyrimidino 2,3-b]indole and 5,6,7,8-tetrahydro-9h-pyrimidino 4,5-b]indole derivatives: crf1 specific ligands |
| US6472402B1 (en) | 1998-04-02 | 2002-10-29 | Neurogen Corporation | Aminoalkyl substituted 5,6,7,8-Tetrahydro-9H-Pyridino [2,3-B]indole derivatives |
| WO1999051608A1 (en) * | 1998-04-03 | 1999-10-14 | Du Pont Pharmaceuticals Company | THIAZOLO[4,5-d]PYRIMIDINES AND PYRIDINES AS CORTICOTROPIN RELEASING FACTOR (CRF) ANTAGONISTS |
| AU4556999A (en) * | 1998-06-09 | 1999-12-30 | Neurogen Corporation | Pyrido[2,3-b]indolizine derivatives and aza analogues thereof; crf1 specific ligands |
| US6509338B1 (en) | 1998-06-22 | 2003-01-21 | Bristol-Myers Squibb Company | Pyrazolo[1,5-A]triazine corticotropin releasing factor antagonists |
| CA2339188A1 (en) * | 1998-08-21 | 2000-03-02 | Dupont Pharmaceuticals Company | Isoxazolo¬4,5-d|pyrimidines as crf antagonists |
| US6531475B1 (en) * | 1998-11-12 | 2003-03-11 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100447141C (zh) * | 2001-07-17 | 2008-12-31 | 葛兰素集团有限公司 | 杂双环crf拮抗剂 |
| CN102947302A (zh) * | 2010-02-18 | 2013-02-27 | 西班牙国家癌症研究中心 | 三唑并[4,5-b]吡啶衍生物 |
| CN102933584A (zh) * | 2010-04-16 | 2013-02-13 | Abbvie公司 | 激酶的吡咯并吡嗪酮抑制剂 |
| CN104411314A (zh) * | 2012-07-09 | 2015-03-11 | 詹森药业有限公司 | 磷酸二酯酶10的抑制剂 |
| CN104411314B (zh) * | 2012-07-09 | 2017-10-20 | 詹森药业有限公司 | 磷酸二酯酶10的抑制剂 |
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