CN1046939C - 氟烷氧基取代的苯甲酰胺类及其制备方法和应用 - Google Patents

氟烷氧基取代的苯甲酰胺类及其制备方法和应用 Download PDF

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Publication number
CN1046939C
CN1046939C CN94192659A CN94192659A CN1046939C CN 1046939 C CN1046939 C CN 1046939C CN 94192659 A CN94192659 A CN 94192659A CN 94192659 A CN94192659 A CN 94192659A CN 1046939 C CN1046939 C CN 1046939C
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halogen
alkyl
hydrogen
phenyl
salt
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Expired - Lifetime
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Chinese (zh)
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CN1126468A (zh
Inventor
H·阿施勒
D·弗洛克齐
B·古特勒
A·哈策曼
C·舒特
R·博默
U·吉利安
H·P·O·沃尔夫
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Takeda GmbH
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Byk Gulden Lomberg Chemische Fabrik GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN94192659A 1993-07-02 1994-07-02 氟烷氧基取代的苯甲酰胺类及其制备方法和应用 Expired - Lifetime CN1046939C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1996/93-9 1993-07-02
CH199693 1993-07-02
CH1996/939 1993-07-02

Publications (2)

Publication Number Publication Date
CN1126468A CN1126468A (zh) 1996-07-10
CN1046939C true CN1046939C (zh) 1999-12-01

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CN94192659A Expired - Lifetime CN1046939C (zh) 1993-07-02 1994-07-02 氟烷氧基取代的苯甲酰胺类及其制备方法和应用

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US (1) US5712298A (enExample)
EP (1) EP0706513B1 (enExample)
JP (1) JP3093271B2 (enExample)
KR (1) KR100331255B1 (enExample)
CN (1) CN1046939C (enExample)
AT (1) ATE217612T1 (enExample)
AU (1) AU687087B2 (enExample)
CA (1) CA2165192C (enExample)
CY (2) CY2389B1 (enExample)
CZ (1) CZ290266B6 (enExample)
DE (2) DE59410119D1 (enExample)
DK (1) DK0706513T3 (enExample)
ES (1) ES2176252T3 (enExample)
FI (1) FI112864B (enExample)
FR (1) FR10C0052I2 (enExample)
HU (1) HU220041B (enExample)
LU (1) LU91709I2 (enExample)
LV (1) LV13074B (enExample)
NO (2) NO305598B1 (enExample)
NZ (1) NZ271316A (enExample)
PL (1) PL178314B1 (enExample)
PT (1) PT706513E (enExample)
RU (1) RU2137754C1 (enExample)
SG (1) SG143011A1 (enExample)
SI (1) SI0706513T1 (enExample)
SK (1) SK283263B6 (enExample)
WO (1) WO1995001338A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102690194A (zh) * 2011-03-24 2012-09-26 上海通远生物科技有限公司 3-环丙基甲氧基-4-二氟甲氧基苯甲酸的制备方法
CN104080770A (zh) * 2011-11-09 2014-10-01 迈兰实验室有限公司 用于制备罗氟司特的改进方法

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