AU2003263393A1 - New heterocyclic amide compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them - Google Patents
New heterocyclic amide compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- AU2003263393A1 AU2003263393A1 AU2003263393A AU2003263393A AU2003263393A1 AU 2003263393 A1 AU2003263393 A1 AU 2003263393A1 AU 2003263393 A AU2003263393 A AU 2003263393A AU 2003263393 A AU2003263393 A AU 2003263393A AU 2003263393 A1 AU2003263393 A1 AU 2003263393A1
- Authority
- AU
- Australia
- Prior art keywords
- inflammatory
- preparation
- treatment
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN804MU2002 | 2002-09-04 | ||
IN804/MUM/2002 | 2002-09-04 | ||
PCT/IB2003/003721 WO2004022536A1 (en) | 2002-09-04 | 2003-09-03 | New heterocyclic amide compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2003263393A1 true AU2003263393A1 (en) | 2004-03-29 |
Family
ID=31972136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003263393A Abandoned AU2003263393A1 (en) | 2002-09-04 | 2003-09-03 | New heterocyclic amide compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2003263393A1 (en) |
WO (1) | WO2004022536A1 (en) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60317918T2 (en) | 2002-10-23 | 2009-01-29 | Glenmark Pharmaceuticals Ltd. | TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES METHOD OF PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEY |
BRPI0409747A (en) | 2003-04-11 | 2006-05-09 | Glenmark Pharmaceuticals Sa | novel heterocyclic compounds useful for treating inflammatory and allergic disorders, processes for their preparation and pharmaceutical compositions containing these |
SI1638933T1 (en) | 2003-06-17 | 2008-10-31 | Pfizer | N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors |
US7163937B2 (en) | 2003-08-21 | 2007-01-16 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
JP4667384B2 (en) | 2003-10-07 | 2011-04-13 | レノビス, インコーポレイテッド | Amide derivatives and pharmaceutical compositions as ion channel ligands and methods of using them |
CN101090885A (en) * | 2004-02-23 | 2007-12-19 | 塔夫茨大学信托人 | Lactams as comformationally constrained peptidomimetic inhibitors |
US20080081825A1 (en) * | 2004-04-28 | 2008-04-03 | Hisao Nakai | Nitrogen-Containing Heterocyclic Compounds and Medicinal Use Thereof |
GB2418425B (en) | 2004-08-11 | 2008-09-03 | Univ Cambridge Tech | Anti-inflammatory agents |
GB2418427A (en) | 2004-09-02 | 2006-03-29 | Univ Cambridge Tech | Ligands for G-protein coupled receptors |
MX2007004400A (en) | 2004-10-13 | 2007-06-19 | Glenmark Pharmaceuticals Sa | Process for the preparation of n-(3, 5-dichloropyrid-4-yl)-4 oromethoxy-8-methanesulfonamido-dibenzo [b, d] diflufuran-1-carboxamide. |
DK1831227T3 (en) | 2004-12-17 | 2013-08-19 | Glenmark Pharmaceuticals Sa | Hitherto unknown, heterocyclic compounds useful in the treatment of inflammatory and allergic disorders |
WO2006064355A2 (en) | 2004-12-17 | 2006-06-22 | Glenmark Pharmaceuticals S.A. | Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders |
US7671062B2 (en) | 2006-07-28 | 2010-03-02 | Bristol-Myers Squibb Company | Modulators of chemokine receptor activity, crystalline forms and process |
US7687508B2 (en) | 2006-07-28 | 2010-03-30 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
US7629351B2 (en) | 2006-07-28 | 2009-12-08 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino) pyrrolidin-1-yl)cyclohexyl)acetamide and other modulators of chemokine receptor activity, crystalline forms and process |
ES2627221T3 (en) * | 2006-12-28 | 2017-07-27 | Rigel Pharmaceuticals, Inc. | N-substituted heterocycloalkyloxybenzamide compounds and methods of use |
CA2678575C (en) * | 2007-02-16 | 2013-10-08 | Emisphere Technologies, Inc. | Compounds having a cyclic moiety and compositions for delivering active agents |
US7662967B2 (en) | 2007-08-02 | 2010-02-16 | Cambridge Enterprise Limited | Anti-inflammatory compounds and compositions |
GB2452696B (en) | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
ES2354550B1 (en) * | 2009-06-26 | 2011-11-15 | Institut Univ. De Ciència I Tecnologia, S.A. | LIBRARY OF N- (1-PHENYL-2-OXO-3-PIPERIDIL) SULFONAMIDS FOR THE DISCOVERY OF DRUGS. |
ES2354551B1 (en) * | 2009-07-01 | 2011-11-15 | Institut Univ. De Ciencia I Tecnologia S.A. | LIBRARIES OF N- (1-PHENYL-2-OXO-3-PIPERIDIL) SULFONAMIDS FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY. |
US8383812B2 (en) | 2009-10-13 | 2013-02-26 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-A][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide, a dual modulator of chemokine receptor activity, crystalline forms and processes |
CN102070638A (en) * | 2009-11-24 | 2011-05-25 | 上海药明康德新药开发有限公司 | Preparation method of hexahydro-pyrrolo [3,4-c] pyrrole-1-ketone derivative |
TW201309689A (en) | 2011-02-07 | 2013-03-01 | Daiichi Sankyo Co Ltd | Amino group-containing pyrrolidinone derivatives |
CN102690194B (en) * | 2011-03-24 | 2014-06-25 | 上海通远生物科技有限公司 | Preparation method of 3-cyclopropylmethoxy-4-difluoromethoxy-benzoic acid |
CN103508883B (en) * | 2012-06-17 | 2015-04-01 | 重庆圣华曦药业股份有限公司 | Method for synthesizing roflumilast intermediate |
WO2014024056A1 (en) | 2012-08-06 | 2014-02-13 | Daiichi Sankyo Company, Limited | Pyrrolidine derivatives with antibacterial properties |
EP2976343A2 (en) | 2013-03-20 | 2016-01-27 | Bayer Pharma Aktiengesellschaft | Substituted n-biphenyl-3-acetylamino-benzamides and n-[3-(acetylamino)phenyl]-biphenyl-carboxamides and their use as inhibitors of the wnt signalling pathway |
AU2014234472A1 (en) | 2013-03-20 | 2015-10-29 | Bayer Pharma Aktiengesellschaft | 3-acetylamino-1-(phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino)benzene derivatives for the treatment of hyperproliferative disorders |
US9815814B2 (en) * | 2013-04-12 | 2017-11-14 | Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives |
CN103351315A (en) * | 2013-07-03 | 2013-10-16 | 北京化工大学 | General preparation method of sulfonyl chloride |
EP3140298A1 (en) | 2014-05-07 | 2017-03-15 | Pfizer Inc. | Tropomyosin-related kinase inhibitors |
CA2976973A1 (en) | 2015-02-20 | 2016-08-25 | Bayer Pharma Aktiengesellschaft | N-phenyl-(morpholin-4-yl or piperazinyl)acetamide derivatives and their use as inhibitors of the wnt signalling pathways |
WO2016131808A1 (en) | 2015-02-20 | 2016-08-25 | Bayer Pharma Aktiengesellschaft | 1,3,4-thiadiazol-2-yl-benzamide derivatives as inhibitorsof the wnt signalling pathway |
JP2018513112A (en) | 2015-02-20 | 2018-05-24 | バイエル・ファルマ・アクティエンゲゼルシャフト | 3-Carbamoylphenyl-4-carboxamide and isophthalamide derivatives as inhibitors of WNT signaling pathway |
HUE054474T2 (en) | 2015-03-30 | 2021-09-28 | Mission Therapeutics Ltd | 1-cyano-pyrrolidine compounds as usp30 inhibitors |
CN105523954B (en) * | 2016-02-05 | 2017-07-18 | 徐江平 | The alkoxy benzamides class phosphodiesterase 4 inhibitors of 3 the third methoxyl group of ring 4 |
CA3058104A1 (en) | 2017-04-26 | 2018-11-01 | Basf Se | Substituted succinimide derivatives as pesticides |
WO2018224455A1 (en) | 2017-06-07 | 2018-12-13 | Basf Se | Substituted cyclopropyl derivatives |
WO2018234488A1 (en) | 2017-06-23 | 2018-12-27 | Basf Se | Substituted cyclopropyl derivatives |
CN107915685A (en) * | 2017-12-11 | 2018-04-17 | 重庆植恩药业有限公司 | A kind of preparation method of hydrobromic acid Vortioxetine intermediate |
WO2019121143A1 (en) | 2017-12-20 | 2019-06-27 | Basf Se | Substituted cyclopropyl derivatives |
CN108003105B (en) * | 2018-01-02 | 2021-09-07 | 上海克琴科技有限公司 | Method for synthesizing micromolecular amino acid derivative ectoin |
US10781172B2 (en) | 2018-06-21 | 2020-09-22 | Northwestern University | Catalysts and methods for enantioselective conjugate additions of amines to unsaturated electrophiles |
EP3613736A1 (en) | 2018-08-22 | 2020-02-26 | Basf Se | Substituted glutarimide derivatives |
US20210340113A1 (en) | 2018-10-29 | 2021-11-04 | Basf Se | Process for preparation of optically enriched aldol compounds |
AU2019376282A1 (en) | 2018-11-06 | 2021-05-20 | Basf Se | Process for preparation of optically enriched isoxazolines |
EP3696177A1 (en) | 2019-02-12 | 2020-08-19 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
EP4043444A1 (en) | 2021-02-11 | 2022-08-17 | Basf Se | Substituted isoxazoline derivatives |
JP2024508249A (en) | 2021-02-11 | 2024-02-26 | ビーエーエスエフ ソシエタス・ヨーロピア | Substituted isoxazoline derivatives |
WO2024033374A1 (en) | 2022-08-11 | 2024-02-15 | Syngenta Crop Protection Ag | Novel arylcarboxamide or arylthioamide compounds |
WO2024089216A1 (en) | 2022-10-27 | 2024-05-02 | Syngenta Crop Protection Ag | Novel sulfur-containing heteroaryl carboxamide compounds |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1041861A (en) * | 1962-03-14 | 1966-09-07 | Organon Labor Ltd | Pyrrolidone derivatives and pharmaceutical preparations containing them |
NL7016899A (en) * | 1969-12-03 | 1971-06-07 | ||
JPS62158253A (en) * | 1985-12-28 | 1987-07-14 | Kirin Brewery Co Ltd | 4-aminopyridinamide derivative |
US5202344A (en) * | 1990-12-11 | 1993-04-13 | G. D. Searle & Co. | N-substituted lactams useful as cholecystokinin antagonists |
IE71647B1 (en) * | 1991-01-28 | 1997-02-26 | Rhone Poulenc Rorer Ltd | Benzamide derivatives |
MX9304571A (en) * | 1992-07-28 | 1994-05-31 | Rhone Poulenc Rorer Ltd | FANILIC COMPOUNDS LINKED TO AN ARYLL OR HETEROARILO THROUGH AN ALIPHATIC RADICAL OR A HETEROGENEOUS ATOM CONTAINING A LINK GROUP. |
GB9304920D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
CA2165192C (en) * | 1993-07-02 | 2001-04-24 | Hermann Amschler | Fluoroalkoxy-substituted benzamides and their use as cyclic nucleotide phosphodiesterase inhibitors |
GB9315595D0 (en) * | 1993-07-28 | 1993-09-08 | Res Inst Medicine Chem | New compounds |
GB9401460D0 (en) * | 1994-01-26 | 1994-03-23 | Rhone Poulenc Rorer Ltd | Compositions of matter |
EP1064298B1 (en) * | 1998-03-19 | 2008-10-08 | Vertex Pharmaceuticals Incorporated | Inhibitors of caspases |
US6887870B1 (en) * | 1999-10-12 | 2005-05-03 | Bristol-Myers Squibb Company | Heterocyclic sodium/proton exchange inhibitors and method |
NZ521248A (en) * | 2000-03-17 | 2004-04-30 | Bristol Myers Squibb Pharma Co | Cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha |
CA2404226A1 (en) * | 2000-03-23 | 2001-09-27 | Takeda Chemical Industries, Ltd. | Furoisoquinoline derivatives, process for producing the same and use thereof |
-
2003
- 2003-09-03 AU AU2003263393A patent/AU2003263393A1/en not_active Abandoned
- 2003-09-03 WO PCT/IB2003/003721 patent/WO2004022536A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2004022536A1 (en) | 2004-03-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |