CA2978942A1 - Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof - Google Patents
Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereofInfo
- Publication number
- CA2978942A1 CA2978942A1 CA2978942A CA2978942A CA2978942A1 CA 2978942 A1 CA2978942 A1 CA 2978942A1 CA 2978942 A CA2978942 A CA 2978942A CA 2978942 A CA2978942 A CA 2978942A CA 2978942 A1 CA2978942 A1 CA 2978942A1
- Authority
- CA
- Canada
- Prior art keywords
- seq
- antibody
- pdl1
- activatable antibody
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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Applications Claiming Priority (7)
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| US201562133231P | 2015-03-13 | 2015-03-13 | |
| US62/133,231 | 2015-03-13 | ||
| US201562139596P | 2015-03-27 | 2015-03-27 | |
| US62/139,596 | 2015-03-27 | ||
| US201562218883P | 2015-09-15 | 2015-09-15 | |
| US62/218,883 | 2015-09-15 | ||
| PCT/US2016/022345 WO2016149201A2 (en) | 2015-03-13 | 2016-03-14 | Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof |
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| CA2978942A1 true CA2978942A1 (en) | 2016-09-22 |
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| CA2978942A Pending CA2978942A1 (en) | 2015-03-13 | 2016-03-14 | Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof |
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| EP (1) | EP3268392A2 (OSRAM) |
| JP (3) | JP6826055B2 (OSRAM) |
| KR (1) | KR20170135860A (OSRAM) |
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| MY (1) | MY194225A (OSRAM) |
| SG (2) | SG11201707383PA (OSRAM) |
| WO (1) | WO2016149201A2 (OSRAM) |
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