CA2277112C - Use of exendins and agonists thereof for the reduction of food intake - Google Patents
Use of exendins and agonists thereof for the reduction of food intake Download PDFInfo
- Publication number
- CA2277112C CA2277112C CA002277112A CA2277112A CA2277112C CA 2277112 C CA2277112 C CA 2277112C CA 002277112 A CA002277112 A CA 002277112A CA 2277112 A CA2277112 A CA 2277112A CA 2277112 C CA2277112 C CA 2277112C
- Authority
- CA
- Canada
- Prior art keywords
- solvent
- exendin
- gly
- peptide
- glu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 230000009467 reduction Effects 0.000 title claims description 8
- 150000001875 compounds Chemical class 0.000 claims abstract description 84
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract description 26
- 230000036528 appetite Effects 0.000 claims abstract description 16
- 235000019789 appetite Nutrition 0.000 claims abstract description 16
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Landscapes
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
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| US3490597P | 1997-01-07 | 1997-01-07 | |
| US60/034,905 | 1997-01-07 | ||
| US5540497P | 1997-08-08 | 1997-08-08 | |
| US60/055,404 | 1997-08-08 | ||
| US6602997P | 1997-11-14 | 1997-11-14 | |
| US6544297P | 1997-11-14 | 1997-11-14 | |
| US60/065,442 | 1997-11-14 | ||
| US60/066,029 | 1997-11-14 | ||
| PCT/US1998/000449 WO1998030231A1 (en) | 1997-01-07 | 1998-01-07 | Use of exendins and agonists thereof for the reduction of food intake |
Publications (2)
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| CA2277112A1 CA2277112A1 (en) | 1998-07-16 |
| CA2277112C true CA2277112C (en) | 2008-08-26 |
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| CA002277112A Expired - Lifetime CA2277112C (en) | 1997-01-07 | 1998-01-07 | Use of exendins and agonists thereof for the reduction of food intake |
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| AU723694B2 (en) * | 1996-06-05 | 2000-08-31 | Roche Diagnostics Gmbh | Exendin analogues, processes for their preparation and medicaments containing them |
| DE69739172D1 (de) | 1996-08-08 | 2009-01-29 | Amylin Pharmaceuticals Inc | Regulation gastrointestinaler beweglichkeit |
| US6956026B2 (en) * | 1997-01-07 | 2005-10-18 | Amylin Pharmaceuticals, Inc. | Use of exendins for the reduction of food intake |
| DE69737916T2 (de) * | 1996-11-12 | 2008-04-03 | Novo Nordisk A/S | Verwendung von GLP-1 Peptiden |
| US7910548B2 (en) * | 1997-06-06 | 2011-03-22 | Amylin Pharmaceuticals, Inc. | Methods for treating obesity |
| US20040022807A1 (en) * | 1998-06-05 | 2004-02-05 | Duft Bradford J | Methods for treating obesity |
| US7157555B1 (en) | 1997-08-08 | 2007-01-02 | Amylin Pharmaceuticals, Inc. | Exendin agonist compounds |
| ES2293688T5 (es) * | 1997-08-08 | 2011-05-04 | Amylin Pharmaceuticals, Inc. | Nuevos compuestos análogos de la exendina. |
| EP1938831A1 (en) * | 1997-08-08 | 2008-07-02 | Amylin Pharmaceuticals, Inc. | Novel exendin agonist compounds |
| EP1941900A1 (en) * | 1997-11-14 | 2008-07-09 | Amylin Pharmaceuticals, Inc. | Novel exendin agonist compounds |
| US7220721B1 (en) | 1997-11-14 | 2007-05-22 | Amylin Pharmaceuticals, Inc. | Exendin agonist peptides |
| AU2003200129B2 (en) * | 1997-11-14 | 2006-06-22 | Amylin Pharmaceuticals, Llc | Novel Exendin Agonist Compounds |
| AU2006225176B2 (en) * | 1997-11-14 | 2009-01-08 | Amylin Pharmaceuticals, Llc | Novel exendin agonist compounds |
| EP1938830A1 (en) * | 1997-11-14 | 2008-07-02 | Amylin Pharmaceuticals, Inc. | Novel exendin agonist compounds |
| BR9815670A (pt) | 1997-11-14 | 2000-10-17 | Amylin Pharmaceuticals Inc | Compostos agonistas de exendina |
| JP2001523688A (ja) * | 1997-11-14 | 2001-11-27 | アミリン・ファーマシューティカルズ，インコーポレイテッド | 新規エキセンジン・アゴニスト化合物 |
| US7223725B1 (en) * | 1997-11-14 | 2007-05-29 | Amylin Pharmaceuticals, Inc. | Exendin agonist compounds |
| US6998387B1 (en) * | 1998-03-19 | 2006-02-14 | Amylin Pharmaceuticals, Inc. | Human appetite control by glucagon-like peptide receptor binding compounds |
| US7259136B2 (en) | 1999-04-30 | 2007-08-21 | Amylin Pharmaceuticals, Inc. | Compositions and methods for treating peripheral vascular disease |
| US6284725B1 (en) * | 1998-10-08 | 2001-09-04 | Bionebraska, Inc. | Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue |
| US6429197B1 (en) | 1998-10-08 | 2002-08-06 | Bionebraska, Inc. | Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain |
| US20030087820A1 (en) * | 1999-01-14 | 2003-05-08 | Young Andrew A. | Novel exendin agonist formulations and methods of administration thereof |
| DE60032331T2 (de) * | 1999-01-14 | 2007-06-21 | Amylin Pharmaceuticals, Inc., San Diego | Exendine zur glucagon suppression |
| JP4426727B2 (ja) * | 1999-01-14 | 2010-03-03 | アミリン・ファーマシューティカルズ，インコーポレイテッド | 新規なエキセンジンアゴニスト製剤とその投与方法 |
| US7399489B2 (en) | 1999-01-14 | 2008-07-15 | Amylin Pharmaceuticals, Inc. | Exendin analog formulations |
| US20050272652A1 (en) | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| US6924264B1 (en) * | 1999-04-30 | 2005-08-02 | Amylin Pharmaceuticals, Inc. | Modified exendins and exendin agonists |
| EP1175443A1 (en) | 1999-04-30 | 2002-01-30 | Amylin Pharmaceuticals, Inc. | Modified exendins and exendin agonists |
| US20090175821A1 (en) * | 1999-05-17 | 2009-07-09 | Bridon Dominique P | Modified therapeutic peptides with extended half-lives in vivo |
| US6514500B1 (en) * | 1999-10-15 | 2003-02-04 | Conjuchem, Inc. | Long lasting synthetic glucagon like peptide {GLP-!} |
| US6506724B1 (en) | 1999-06-01 | 2003-01-14 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for the treatment of gestational diabetes mellitus |
| EP1076066A1 (en) * | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
| US6528486B1 (en) | 1999-07-12 | 2003-03-04 | Zealand Pharma A/S | Peptide agonists of GLP-1 activity |
| WO2001051078A1 (en) * | 2000-01-10 | 2001-07-19 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for modulation of triglyceride levels and treatment of dyslipidemia |
| EP1263458B1 (en) * | 2000-03-08 | 2005-11-16 | Novo Nordisk A/S | Lowering serum cholesterol |
| ATE450269T1 (de) | 2000-12-14 | 2009-12-15 | Amylin Pharmaceuticals Inc | Peptid pyyä3-36ü zur behandlung von stoffwechselkrankheiten |
| US20090281032A1 (en) * | 2001-03-01 | 2009-11-12 | Peter Raymond Flatt | Modified CCK peptides |
| ATE536881T1 (de) | 2001-07-31 | 2011-12-15 | Us Gov Health & Human Serv | Glp-1, exendin-4, peptid-analoga und verwendungen davon |
| GB0121709D0 (en) * | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
| US7459432B2 (en) * | 2001-09-24 | 2008-12-02 | Imperial College Innovations Ltd. | Modification of feeding behavior |
| AU2002351752A1 (en) * | 2001-12-29 | 2003-07-30 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
| CA2475173A1 (en) * | 2002-01-08 | 2003-07-17 | Amylin Pharmaceuticals, Inc. | Use of amylin agonists to modulate triglycerides |
| US8058233B2 (en) * | 2002-01-10 | 2011-11-15 | Oregon Health And Science University | Modification of feeding behavior using PYY and GLP-1 |
| EP2329839B1 (en) * | 2002-01-10 | 2015-09-16 | Imperial Innovations Limited | Modification of feeding behavior by GLP-1 and PYY |
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1998
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- 1998-01-07 DK DK98904545T patent/DK0996459T3/da active
- 1998-01-07 EP EP98904545A patent/EP0996459B1/en not_active Expired - Lifetime
- 1998-01-07 PT PT50119783T patent/PT1629849E/pt unknown
- 1998-01-07 DK DK05011978.3T patent/DK1629849T4/en active
- 1998-01-07 DE DE122007000044C patent/DE122007000044I2/de active Active
- 1998-01-07 DE DE69831673.8T patent/DE69831673C5/de not_active Expired - Lifetime
- 1998-01-07 EP EP05011978.3A patent/EP1629849B2/en not_active Expired - Lifetime
- 1998-01-07 CA CA002277112A patent/CA2277112C/en not_active Expired - Lifetime
- 1998-01-07 ES ES98904545T patent/ES2247676T3/es not_active Expired - Lifetime
- 1998-01-07 AT AT98904545T patent/ATE304864T1/de active
- 1998-01-07 ES ES05011978.3T patent/ES2425559T5/es not_active Expired - Lifetime
- 1998-01-07 AU AU62394/98A patent/AU739020B2/en not_active Expired
- 1998-01-07 WO PCT/US1998/000449 patent/WO1998030231A1/en active IP Right Grant
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2002
- 2002-06-28 US US10/187,051 patent/US6989366B2/en not_active Expired - Fee Related
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2004
- 2004-07-19 US US10/894,999 patent/US7297761B2/en not_active Expired - Fee Related
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- 2004-10-14 US US10/966,337 patent/US7138375B2/en not_active Expired - Fee Related
- 2004-10-15 US US10/964,887 patent/US7115569B2/en not_active Expired - Fee Related
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2006
- 2006-03-03 US US11/368,225 patent/US7419952B2/en not_active Expired - Fee Related
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2007
- 2007-05-16 BE BE2007C038C patent/BE2007C038I2/fr unknown
- 2007-05-16 FR FR07C0031C patent/FR07C0031I2/fr active Active
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