AU4050797A - Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators - Google Patents
Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulatorsInfo
- Publication number
- AU4050797A AU4050797A AU40507/97A AU4050797A AU4050797A AU 4050797 A AU4050797 A AU 4050797A AU 40507/97 A AU40507/97 A AU 40507/97A AU 4050797 A AU4050797 A AU 4050797A AU 4050797 A AU4050797 A AU 4050797A
- Authority
- AU
- Australia
- Prior art keywords
- diabetes
- prevention
- treatment
- type
- cardiovascular disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2294996P | 1996-08-02 | 1996-08-02 | |
US60022949 | 1996-08-02 | ||
PCT/US1997/013605 WO1998005331A2 (en) | 1996-08-02 | 1997-08-01 | Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4050797A true AU4050797A (en) | 1998-02-25 |
Family
ID=21812265
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU40507/97A Abandoned AU4050797A (en) | 1996-08-02 | 1997-08-01 | Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0930882A2 (en) |
AU (1) | AU4050797A (en) |
WO (1) | WO1998005331A2 (en) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7115728B1 (en) | 1995-01-30 | 2006-10-03 | Ligand Pharmaceutical Incorporated | Human peroxisome proliferator activated receptor γ |
DK1629849T4 (en) | 1997-01-07 | 2017-12-04 | Amylin Pharmaceuticals Llc | Pharmaceutical compositions comprising exedins and agonists thereof |
FR2774591B1 (en) * | 1998-02-12 | 2000-05-05 | Lipha | PHARMACEUTICAL COMPOSITION COMPRISING THE ASSOCIATION OF METFORMIN AND FIBRATE AND THE USE THEREOF FOR THE PREPARATION OF MEDICINES FOR REDUCING HYPERGLYCEMIA |
NZ508066A (en) | 1998-05-11 | 2003-03-28 | Takeda Chemical Industries Ltd | Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity |
DE19823831A1 (en) * | 1998-05-28 | 1999-12-02 | Probiodrug Ges Fuer Arzneim | New pharmaceutical use of isoleucyl thiazolidide and its salts |
AU4250200A (en) * | 1999-04-19 | 2000-11-02 | Coelacanth Corporation | Ppar-(gamma) agonists as agents for the treatment of type ii diabetes |
AU4652600A (en) * | 1999-04-23 | 2000-11-10 | Curagen Corporation | Method of identifying ligands for the peroxisome proliferator activated receptorgamma using differential gene expression |
DK1206457T3 (en) | 1999-08-27 | 2004-02-16 | Lilly Co Eli | Biaryl-oxa (thia) zole derivatives and their use as modulators PPAPs |
WO2001044512A2 (en) * | 1999-12-16 | 2001-06-21 | Curagen Corporation | Method of identifying ligands for the peroxisome proliferator activated receptor gamma using differential gene expression |
DK1246638T4 (en) * | 2000-01-10 | 2014-09-22 | Amylin Pharmaceuticals Llc | Use of extendins and agonists thereof in the treatment of hypertriglyceridemia |
WO2001051454A1 (en) * | 2000-01-13 | 2001-07-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
GB0002667D0 (en) * | 2000-02-04 | 2000-03-29 | Glaxo Group Ltd | medicamesnts |
WO2001066098A2 (en) * | 2000-03-09 | 2001-09-13 | Aventis Pharma Deutschland Gmbh | Therapeutic uses of ppar mediators |
HUP0301146A3 (en) * | 2000-04-28 | 2004-08-30 | Sankyo Co | 2-chlor-5-nitrophenyl carboxamide derivatives, pharmaceutical compositions containing them and their use |
MXPA02012619A (en) * | 2000-06-16 | 2003-04-10 | Smithkline Beecham Plc | Treatment and prevention of cardiac insulin resistance associated conditions. |
IT1317885B1 (en) * | 2000-08-01 | 2003-07-15 | Sigma Tau Ind Farmaceuti | USE OF FIBRATES FOR THE PREPARATION OF A USEFUL DRUG IN THE TREATMENT OF CONGESTIAL HEART INSUFFICIENCY. |
US7071181B2 (en) * | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
EP1911462A3 (en) | 2001-01-26 | 2011-11-30 | Schering Corporation | Compositions comprising a sterol absorption inhibitor |
WO2002064130A1 (en) * | 2001-02-15 | 2002-08-22 | Pfizer Products Inc. | Proliferative activator receptor (ppar) compounds |
BR0207285A (en) * | 2001-02-15 | 2004-02-10 | Pfizer Producs Inc | Ppar agonists |
CN1275949C (en) | 2001-03-28 | 2006-09-20 | 先灵公司 | Enantioselective synthesis of azetidinone intermediate compounds |
CA2445322C (en) * | 2001-04-25 | 2011-06-14 | Takeda Chemical Industries, Ltd. | Use of the abc expression promoting agent pioglitazone for the treatment of arteriosclerosis obliterans |
WO2003059378A2 (en) | 2001-12-29 | 2003-07-24 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
ITRM20020014A1 (en) | 2002-01-15 | 2003-07-15 | Sigma Tau Ind Farmaceuti | DERIVATIVES OF A-PHENYLTHIOCARBOXYL AND A-PHYLYOXYCARBOXYL ACIDS USEFUL FOR THE TREATMENT OF DISEASES THAT RESPOND TO THE ACTIVATION OF |
CA2481371A1 (en) * | 2002-03-11 | 2003-09-18 | Peter Zahradka | Use of ppar alpha agonists for the treatment of vascular and renal diseases |
US7811593B2 (en) * | 2002-03-25 | 2010-10-12 | Jian Luo | Pharmaceutical composition with combined active agents and methods for using the same |
EP1388352A1 (en) * | 2002-08-08 | 2004-02-11 | Laboratoires Fournier S.A. | Use of a ppar-alpha agonist to treat patients suffering from weight gain associated with a ppar-gamma agonist treatment |
EP1388351A1 (en) * | 2002-08-08 | 2004-02-11 | Laboratoires Fournier S.A. | Use of fibrate to treat weight gain associated with rosiglitazone treatment |
KR100875318B1 (en) | 2002-11-26 | 2008-12-22 | 화이자 프로덕츠 인크. | Phenyl Substituted Piperidine Compounds for Use as PPAR Activators |
EP1424070A1 (en) * | 2002-11-28 | 2004-06-02 | Fournier Laboratories Ireland Limited | Combination of a PPAR alpha agonist and metformin for decreasing the serum triglycerides |
US6987118B2 (en) | 2003-05-21 | 2006-01-17 | Pfizer Inc. | Tetrahydroisoquinoline derivatives as PPAR-alpha activators |
CN101772513B (en) | 2007-06-04 | 2013-11-13 | 协同医药品公司 | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
ES2522968T3 (en) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
JP2011528375A (en) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders |
US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
US9486433B2 (en) | 2012-10-12 | 2016-11-08 | Mochida Pharmaceuticals Co. Ltd. | Compositions and methods for treating non-alcoholic steatohepatitis |
EP2968245B1 (en) | 2013-03-15 | 2021-05-05 | Mochida Pharmaceutical Co., Ltd. | Compositions and methods for treating non-alcoholic steatohepatitis |
JP2016514671A (en) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | Guanylate cyclase agonists and uses thereof |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
US10441560B2 (en) | 2013-03-15 | 2019-10-15 | Mochida Pharmaceutical Co., Ltd. | Compositions and methods for treating non-alcoholic steatohepatitis |
WO2014197720A2 (en) | 2013-06-05 | 2014-12-11 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
CA2926685A1 (en) | 2013-10-09 | 2015-04-16 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3729209A1 (en) * | 1987-09-01 | 1989-03-09 | Boehringer Mannheim Gmbh | USE OF BEZAFIBRATE FOR TREATING DIABETES |
JP3852621B2 (en) * | 1992-01-21 | 2006-12-06 | あすか製薬株式会社 | Vascular endothelial cell function improving agent |
NZ274346A (en) * | 1993-09-15 | 1997-06-24 | Sankyo Co | Use of various thiazolidine-2,4-dione and oxazolidine-2,4-dione derivatives to prevent or delay onset of non-insulin dependent diabetes mellitus |
US5478852C1 (en) * | 1993-09-15 | 2001-03-13 | Sankyo Co | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus |
BR9610624A (en) * | 1995-09-18 | 1999-03-16 | Ligand Pharm Inc | Treatment of dmndi with rxr agonists |
GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
-
1997
- 1997-08-01 WO PCT/US1997/013605 patent/WO1998005331A2/en not_active Application Discontinuation
- 1997-08-01 AU AU40507/97A patent/AU4050797A/en not_active Abandoned
- 1997-08-01 EP EP97938101A patent/EP0930882A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO1998005331A2 (en) | 1998-02-12 |
EP0930882A2 (en) | 1999-07-28 |
WO1998005331A3 (en) | 1998-05-07 |
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