AU2011290126B2 - Heterocyclic compound and use thereof - Google Patents

Heterocyclic compound and use thereof Download PDF

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Publication number
AU2011290126B2
AU2011290126B2 AU2011290126A AU2011290126A AU2011290126B2 AU 2011290126 B2 AU2011290126 B2 AU 2011290126B2 AU 2011290126 A AU2011290126 A AU 2011290126A AU 2011290126 A AU2011290126 A AU 2011290126A AU 2011290126 B2 AU2011290126 B2 AU 2011290126B2
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Australia
Prior art keywords
optionally substituted
halogen atom
alkyl
group
substituted
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AU2011290126A
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AU2011290126A1 (en
Inventor
Yasutomi Asano
Eiji Honda
Toshihiro Imaeda
Masakuni Kori
Michiyo Mochizuki
Shinji Nakamura
Masashi Toyofuku
Osamu Ujikawa
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Publication of AU2011290126A1 publication Critical patent/AU2011290126A1/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AU2011290126A 2010-08-10 2011-08-09 Heterocyclic compound and use thereof Active AU2011290126B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010-179577 2010-08-10
JP2010179577 2010-08-10
PCT/JP2011/068497 WO2012020848A1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

Publications (2)

Publication Number Publication Date
AU2011290126A1 AU2011290126A1 (en) 2013-03-07
AU2011290126B2 true AU2011290126B2 (en) 2016-01-07

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AU2011290126A Active AU2011290126B2 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

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US (11) US8575154B2 (enExample)
EP (1) EP2603513B1 (enExample)
JP (2) JP5788496B2 (enExample)
KR (1) KR101852215B1 (enExample)
CN (2) CN104926837A (enExample)
AR (1) AR082618A1 (enExample)
AU (1) AU2011290126B2 (enExample)
BR (1) BR112013002250B1 (enExample)
CA (1) CA2807460C (enExample)
CL (1) CL2013000380A1 (enExample)
CO (1) CO6680700A2 (enExample)
CR (1) CR20130066A (enExample)
CY (1) CY1123507T1 (enExample)
DK (1) DK2603513T3 (enExample)
DO (1) DOP2013000030A (enExample)
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GE (1) GEP20156216B (enExample)
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HU (1) HUE049460T2 (enExample)
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PL (1) PL2603513T3 (enExample)
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RS (1) RS60311B1 (enExample)
SG (1) SG187656A1 (enExample)
SI (1) SI2603513T1 (enExample)
TW (1) TWI504604B (enExample)
UA (1) UA111594C2 (enExample)
UY (1) UY33551A (enExample)
WO (1) WO2012020848A1 (enExample)
ZA (1) ZA201301120B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20131116A1 (es) * 2010-08-10 2013-10-24 Takeda Pharmaceutical Compuestos heterociclicos potenciadores de ampa
US9527807B2 (en) 2011-04-05 2016-12-27 Takeda Pharmaceutical Company Limited Sulfonamide derivative and use thereof
JP6134654B2 (ja) * 2012-02-08 2017-05-24 武田薬品工業株式会社 複素環化合物およびその用途
WO2014201411A1 (en) * 2013-06-13 2014-12-18 Veroscience Llc Compositions and methods for treating metabolic disorders
JP6026024B2 (ja) 2013-06-27 2016-11-16 ファイザー・インク 複素芳香族化合物およびそのドーパミンd1リガンドとしての使用
US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
HUE049827T2 (hu) 2013-12-03 2020-10-28 Fmc Corp Pirrolidinonok mint herbicidek
KR102479858B1 (ko) 2014-07-02 2022-12-21 에프엠씨 코포레이션 피페리디논계 제초제
AU2015361018B2 (en) 2014-12-08 2020-01-16 Fmc Corporation 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones
AU2016246410B2 (en) 2015-04-10 2020-11-05 Fmc Corporation Substituted cyclic amides as herbicides
BR112017020094B1 (pt) 2015-04-27 2022-01-11 Fmc Corporation Composto, composições herbicidas, mistura de herbicida e método para controlar o crescimento de vegetação indesejada
KR20170140382A (ko) 2015-04-29 2017-12-20 얀센 파마슈티카 엔.브이. 아자벤즈이미다졸 및 ampa 수용체 조절제로서의 이의 용도
BR112017023038A2 (pt) * 2015-04-29 2018-07-03 Janssen Pharmaceutica Nv imidazopirazinas e pirazolopirimidinas e seu uso como moduladores do receptor ampa
WO2016182780A1 (en) 2015-05-12 2016-11-17 E I Du Pont De Nemours And Company Aryl substituted bicyclic compounds as herbicides
JP6869192B2 (ja) 2015-05-29 2021-05-12 エフ エム シー コーポレーションFmc Corporation 除草剤としての置換環状アミド
RU2017142979A (ru) 2015-06-02 2019-07-15 ЭфЭмСи Корпорейшн Замещенные циклические амиды и их применение в качестве гербицидов
CA2993000C (en) 2015-07-31 2024-01-23 E.I. Du Pont De Nemours & Company Cyclic n-carboxamide compounds useful as herbicides
CN107709342B (zh) * 2015-08-06 2021-09-03 豪夫迈·罗氏有限公司 制备乙酰半乳糖胺酸衍生物的方法
US20170181292A1 (en) * 2015-12-16 2017-06-22 Rohm And Haas Electronic Materials Llc Method for forming organic coating on nickel surface
CN105669731B (zh) * 2016-01-10 2017-06-30 沧州普瑞东方科技有限公司 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法
AU2017378640B2 (en) 2016-12-21 2022-03-03 Fmc Corporation Nitrone herbicides
CN107892697B (zh) 2016-12-26 2020-11-03 郑州泰基鸿诺医药股份有限公司 一种[1,3]噻嗪-2-胺类化合物及应用,药物组合物
JP7201609B2 (ja) 2017-03-21 2023-01-10 エフ エム シー コーポレーション ピロリジノン及びこれらを調製するためのプロセス
WO2018175231A1 (en) 2017-03-21 2018-09-27 Fmc Corporation Herbicidal mixture, composition and method
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
US11407748B2 (en) 2017-10-06 2022-08-09 Takeda Pharmaceutical Company Limited Substituted pyrido[1,2-a]pyrimidines and pyrazino[1,2-a]pyrimidines for enhancing AMPA receptor function
JP7250687B2 (ja) 2017-10-06 2023-04-03 武田薬品工業株式会社 複素環化合物
PE20221341A1 (es) 2019-09-16 2022-09-13 Takeda Pharmaceuticals Co Derivados de piridazin-3(2h)-ona fusionados con azol
JP2023526249A (ja) * 2020-05-15 2023-06-21 武田薬品工業株式会社 うつ病の処置
CN113943294A (zh) * 2020-07-15 2022-01-18 成都海博为药业有限公司 一种作为btk抑制剂的化合物及其制备方法与用途
WO2025226591A1 (en) 2024-04-22 2025-10-30 Neurocrine Biosciences, Inc. Methods of administering 9-[4-(cyclohexyloxy)phenyl]-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide without side effects
WO2026050231A1 (en) 2024-08-27 2026-03-05 Neurocrine Biosciences, Inc. Method of treating a bipolar disorder

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0285851A (ja) * 1988-09-22 1990-03-27 Konica Corp 新規な写真用カプラー
JPH0437742A (ja) * 1990-06-03 1992-02-07 Konica Corp 新規な染料を含有するハロゲン化銀写真感光材料
JP2009248543A (ja) * 2008-04-11 2009-10-29 Fujifilm Corp 光情報記録媒体および情報記録方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0437742Y2 (enExample) 1986-10-22 1992-09-04
JPH037742A (ja) 1989-06-05 1991-01-14 Toyo Tire & Rubber Co Ltd ラバーチエーン用ゴム組成物
JPH04119890A (ja) 1990-09-11 1992-04-21 Konica Corp ピラゾロチアジアジン系色素
JP3430375B2 (ja) 1993-11-12 2003-07-28 コニカ株式会社 感熱転写材料及び該材料に好適な色素
DE19704923A1 (de) 1997-02-10 1998-08-13 Hoechst Schering Agrevo Gmbh Klebstoffhaltige Schädlingsbekämpfungsmittel
AU5271900A (en) 1999-11-04 2001-05-14 Colorado State University Research Foundation Method and device for attracting insects
FR2801587B1 (fr) 1999-11-30 2002-01-11 Adir Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
MXPA04003297A (es) 2001-10-10 2004-07-23 Neurosearch As Derivados novedosos de benzotiacina su preparacion y uso.
FR2833955B1 (fr) 2001-12-21 2004-01-30 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2854634B1 (fr) 2003-05-05 2005-07-08 Servier Lab Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2865474B1 (fr) 2004-01-26 2008-06-13 Servier Lab Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2879201B1 (fr) 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2007147208A1 (en) 2006-06-23 2007-12-27 Nufarm Australia Limited Phenoxy alkanoate herbicidal composition and method of preparation and use
KR20090082278A (ko) 2006-12-11 2009-07-29 일라이 릴리 앤드 캄파니 Ampa 수용체 강화제
US20080167374A1 (en) 2007-01-09 2008-07-10 Loveland Products, Inc. Pesticide composition and method of use
WO2009061699A1 (en) * 2007-11-05 2009-05-14 Schering Corporation Gamma secretase modulators
US8642660B2 (en) * 2007-12-21 2014-02-04 The University Of Rochester Method for altering the lifespan of eukaryotic organisms
JPWO2009119088A1 (ja) 2008-03-25 2011-07-21 武田薬品工業株式会社 複素環化合物
TW201012803A (en) * 2008-06-06 2010-04-01 Organon Nv Heterocyclic derivatives
WO2010054067A1 (en) 2008-11-06 2010-05-14 Schering Corporation Gamma secretase modulators
TW201030002A (en) 2009-01-16 2010-08-16 Bristol Myers Squibb Co Bicyclic compounds for the reduction of beta-amyloid production
JP2012051806A (ja) 2009-02-26 2012-03-15 Eisai R & D Management Co Ltd イミダゾリルピラジン誘導体
FR2943342B1 (fr) 2009-03-20 2011-03-04 Servier Lab Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
WO2010140339A1 (ja) 2009-06-01 2010-12-09 武田薬品工業株式会社 複素環化合物
JPWO2011007756A1 (ja) 2009-07-13 2012-12-27 武田薬品工業株式会社 複素環化合物及びその用途
WO2011036889A1 (ja) 2009-09-25 2011-03-31 武田薬品工業株式会社 複素環化合物
WO2011036885A1 (ja) 2009-09-25 2011-03-31 武田薬品工業株式会社 複素環化合物
PE20131116A1 (es) * 2010-08-10 2013-10-24 Takeda Pharmaceutical Compuestos heterociclicos potenciadores de ampa

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0285851A (ja) * 1988-09-22 1990-03-27 Konica Corp 新規な写真用カプラー
JPH0437742A (ja) * 1990-06-03 1992-02-07 Konica Corp 新規な染料を含有するハロゲン化銀写真感光材料
JP2009248543A (ja) * 2008-04-11 2009-10-29 Fujifilm Corp 光情報記録媒体および情報記録方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CAS Registry No. 732959-59-0 *
WARD, S. E. et al., Current Medicinal Chemistry 2010, 17(30), 3503-3513 *

Also Published As

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JP6113789B2 (ja) 2017-04-12
US8778934B2 (en) 2014-07-15
US20130184266A1 (en) 2013-07-18
NZ607593A (en) 2015-01-30
MX349470B (es) 2017-07-31
GEP20156216B (en) 2015-01-12
US20170022222A1 (en) 2017-01-26
AR082618A1 (es) 2012-12-19
US20130190291A1 (en) 2013-07-25
CN103180326A (zh) 2013-06-26
US20200317692A1 (en) 2020-10-08
EA022078B1 (ru) 2015-10-30
WO2012020848A1 (en) 2012-02-16
CY1123507T1 (el) 2022-03-24
KR101852215B1 (ko) 2018-04-25
ECSP13012478A (es) 2013-04-30
UY33551A (es) 2012-03-30
SI2603513T1 (sl) 2020-07-31
BR112013002250A2 (pt) 2016-05-24
EP2603513A1 (en) 2013-06-19
DOP2013000030A (es) 2013-03-15
US11279713B2 (en) 2022-03-22
US20180162875A1 (en) 2018-06-14
US20120077799A1 (en) 2012-03-29
PT2603513T (pt) 2020-06-08
UA111594C2 (uk) 2016-05-25
TW201217386A (en) 2012-05-01
US20140080817A1 (en) 2014-03-20
JP2016006080A (ja) 2016-01-14
MA34509B1 (fr) 2013-09-02
BR112013002250B1 (pt) 2020-10-27
DK2603513T3 (da) 2020-06-15
RS60311B1 (sr) 2020-07-31
JP2013535408A (ja) 2013-09-12
EA201390222A1 (ru) 2013-08-30
US8575154B2 (en) 2013-11-05
CA2807460C (en) 2018-09-18
CR20130066A (es) 2013-05-03
CL2013000380A1 (es) 2013-05-31
US10654874B2 (en) 2020-05-19
KR20130138738A (ko) 2013-12-19
PE20131116A1 (es) 2013-10-24
JP5788496B2 (ja) 2015-09-30
HUE049460T2 (hu) 2020-09-28
US20150353578A1 (en) 2015-12-10
US20150073137A1 (en) 2015-03-12
TWI504604B (zh) 2015-10-21
AU2011290126A1 (en) 2013-03-07
ES2793723T3 (es) 2020-11-16
MX2013001614A (es) 2013-07-05
US8916551B2 (en) 2014-12-23
CN104926837A (zh) 2015-09-23
EP2603513B1 (en) 2020-03-11
CN103180326B (zh) 2015-06-10
HRP20200844T1 (hr) 2020-08-21
PL2603513T3 (pl) 2020-07-27
US9150591B2 (en) 2015-10-06
ZA201301120B (en) 2014-04-30
US20190263832A1 (en) 2019-08-29
CA2807460A1 (en) 2012-02-16
CO6680700A2 (es) 2013-05-31
IL224452A (en) 2017-11-30
PH12013500247A1 (en) 2013-03-11
LT2603513T (lt) 2020-05-25
US9884875B2 (en) 2018-02-06
US20240360156A1 (en) 2024-10-31
US9499568B2 (en) 2016-11-22
WO2012020848A8 (en) 2012-09-27
SG187656A1 (en) 2013-03-28
MY165908A (en) 2018-05-18

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