DOP2013000030A - Compuesto heterociclico y su uso - Google Patents

Compuesto heterociclico y su uso

Info

Publication number
DOP2013000030A
DOP2013000030A DO2013000030A DO2013000030A DOP2013000030A DO P2013000030 A DOP2013000030 A DO P2013000030A DO 2013000030 A DO2013000030 A DO 2013000030A DO 2013000030 A DO2013000030 A DO 2013000030A DO P2013000030 A DOP2013000030 A DO P2013000030A
Authority
DO
Dominican Republic
Prior art keywords
compound
heterociclical
saies
isoxazolepropionic
adhd
Prior art date
Application number
DO2013000030A
Other languages
English (en)
Inventor
Osamu Ujikawa
Masakuni Kori
Eiji Honda
Toshihiro Imaeda
Shinji Nakamura
Masashi Toyofuku
Yasutomi Asano
Michiyo Mochizuki
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of DOP2013000030A publication Critical patent/DOP2013000030A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se proporciona un compuesto representado por la fórmula (l): en donde cada símbolo es como se define en la memoria descriptiva o una de sus saies, que tiene una acción potenciadora del receptor de AM PA (ácido a—amino—3—h idroxi—5—metil—4—isoxazolpropiónico). El compuesto de la presente invención es de utilidad como un fármaco preventivo o terapéutico para depresión, esquizofrénia, enfermedad de Alzheimer o trastorno de hiperactividad de déficit de atención (ADHD), y sim ilares.
DO2013000030A 2010-08-10 2013-02-05 Compuesto heterociclico y su uso DOP2013000030A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010179577 2010-08-10

Publications (1)

Publication Number Publication Date
DOP2013000030A true DOP2013000030A (es) 2013-03-15

Family

ID=44534564

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2013000030A DOP2013000030A (es) 2010-08-10 2013-02-05 Compuesto heterociclico y su uso

Country Status (39)

Country Link
US (11) US9150591B2 (es)
EP (1) EP2603513B1 (es)
JP (2) JP5788496B2 (es)
KR (1) KR101852215B1 (es)
CN (2) CN103180326B (es)
AR (1) AR082618A1 (es)
AU (1) AU2011290126B2 (es)
BR (1) BR112013002250B1 (es)
CA (1) CA2807460C (es)
CL (1) CL2013000380A1 (es)
CO (1) CO6680700A2 (es)
CR (1) CR20130066A (es)
CY (1) CY1123507T1 (es)
DK (1) DK2603513T3 (es)
DO (1) DOP2013000030A (es)
EA (1) EA022078B1 (es)
EC (1) ECSP13012478A (es)
ES (1) ES2793723T3 (es)
GE (1) GEP20156216B (es)
HR (1) HRP20200844T1 (es)
HU (1) HUE049460T2 (es)
IL (1) IL224452A (es)
LT (1) LT2603513T (es)
MA (1) MA34509B1 (es)
MX (1) MX349470B (es)
MY (1) MY165908A (es)
NZ (1) NZ607593A (es)
PE (1) PE20131116A1 (es)
PH (1) PH12013500247A1 (es)
PL (1) PL2603513T3 (es)
PT (1) PT2603513T (es)
RS (1) RS60311B1 (es)
SG (1) SG187656A1 (es)
SI (1) SI2603513T1 (es)
TW (1) TWI504604B (es)
UA (1) UA111594C2 (es)
UY (1) UY33551A (es)
WO (1) WO2012020848A1 (es)
ZA (1) ZA201301120B (es)

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CN107892697B (zh) 2016-12-26 2020-11-03 郑州泰基鸿诺医药股份有限公司 一种[1,3]噻嗪-2-胺类化合物及应用，药物组合物
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Also Published As

Publication number Publication date
US9884875B2 (en) 2018-02-06
US20120077799A1 (en) 2012-03-29
KR20130138738A (ko) 2013-12-19
PE20131116A1 (es) 2013-10-24
HRP20200844T1 (hr) 2020-08-21
ES2793723T3 (es) 2020-11-16
CA2807460C (en) 2018-09-18
US20170022222A1 (en) 2017-01-26
NZ607593A (en) 2015-01-30
KR101852215B1 (ko) 2018-04-25
US11279713B2 (en) 2022-03-22
AU2011290126B2 (en) 2016-01-07
WO2012020848A8 (en) 2012-09-27
BR112013002250A2 (pt) 2016-05-24
EP2603513A1 (en) 2013-06-19
US20190263832A1 (en) 2019-08-29
JP5788496B2 (ja) 2015-09-30
EP2603513B1 (en) 2020-03-11
US20140080817A1 (en) 2014-03-20
MY165908A (en) 2018-05-18
PT2603513T (pt) 2020-06-08
US9150591B2 (en) 2015-10-06
AR082618A1 (es) 2012-12-19
US20240360156A1 (en) 2024-10-31
US8916551B2 (en) 2014-12-23
SI2603513T1 (sl) 2020-07-31
UA111594C2 (uk) 2016-05-25
US20150353578A1 (en) 2015-12-10
LT2603513T (lt) 2020-05-25
US20200317692A1 (en) 2020-10-08
GEP20156216B (en) 2015-01-12
MX349470B (es) 2017-07-31
CA2807460A1 (en) 2012-02-16
ECSP13012478A (es) 2013-04-30
US20130184266A1 (en) 2013-07-18
JP2013535408A (ja) 2013-09-12
MA34509B1 (fr) 2013-09-02
EA022078B1 (ru) 2015-10-30
US9499568B2 (en) 2016-11-22
PH12013500247A1 (en) 2013-03-11
DK2603513T3 (da) 2020-06-15
CY1123507T1 (el) 2022-03-24
TWI504604B (zh) 2015-10-21
US8575154B2 (en) 2013-11-05
WO2012020848A1 (en) 2012-02-16
CL2013000380A1 (es) 2013-05-31
IL224452A (en) 2017-11-30
US10654874B2 (en) 2020-05-19
BR112013002250B1 (pt) 2020-10-27
RS60311B1 (sr) 2020-07-31
MX2013001614A (es) 2013-07-05
SG187656A1 (en) 2013-03-28
PL2603513T3 (pl) 2020-07-27
CN103180326A (zh) 2013-06-26
CO6680700A2 (es) 2013-05-31
UY33551A (es) 2012-03-30
CN104926837A (zh) 2015-09-23
EA201390222A1 (ru) 2013-08-30
CN103180326B (zh) 2015-06-10
US20130190291A1 (en) 2013-07-25
ZA201301120B (en) 2014-04-30
JP2016006080A (ja) 2016-01-14
HUE049460T2 (hu) 2020-09-28
AU2011290126A1 (en) 2013-03-07
US20150073137A1 (en) 2015-03-12
TW201217386A (en) 2012-05-01
US8778934B2 (en) 2014-07-15
JP6113789B2 (ja) 2017-04-12
US20180162875A1 (en) 2018-06-14
CR20130066A (es) 2013-05-03

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