DK2603513T3 - Heterocyklisk forbindelse og anvendelse deraf som AMPA-receptorpositiv allosterisk modulator - Google Patents
Heterocyklisk forbindelse og anvendelse deraf som AMPA-receptorpositiv allosterisk modulator Download PDFInfo
- Publication number
- DK2603513T3 DK2603513T3 DK11749944.2T DK11749944T DK2603513T3 DK 2603513 T3 DK2603513 T3 DK 2603513T3 DK 11749944 T DK11749944 T DK 11749944T DK 2603513 T3 DK2603513 T3 DK 2603513T3
- Authority
- DK
- Denmark
- Prior art keywords
- heterocyclic compound
- positive allosteric
- receptor positive
- ampa receptor
- allosteric modulator
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2010179577 | 2010-08-10 | ||
PCT/JP2011/068497 WO2012020848A1 (en) | 2010-08-10 | 2011-08-09 | Heterocyclic compound and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2603513T3 true DK2603513T3 (da) | 2020-06-15 |
Family
ID=44534564
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK11749944.2T DK2603513T3 (da) | 2010-08-10 | 2011-08-09 | Heterocyklisk forbindelse og anvendelse deraf som AMPA-receptorpositiv allosterisk modulator |
Country Status (38)
Country | Link |
---|---|
US (10) | US8575154B2 (da) |
EP (1) | EP2603513B1 (da) |
JP (2) | JP5788496B2 (da) |
KR (1) | KR101852215B1 (da) |
CN (2) | CN104926837A (da) |
AR (1) | AR082618A1 (da) |
AU (1) | AU2011290126B2 (da) |
BR (1) | BR112013002250B1 (da) |
CA (1) | CA2807460C (da) |
CL (1) | CL2013000380A1 (da) |
CO (1) | CO6680700A2 (da) |
CR (1) | CR20130066A (da) |
CY (1) | CY1123507T1 (da) |
DK (1) | DK2603513T3 (da) |
DO (1) | DOP2013000030A (da) |
EA (1) | EA022078B1 (da) |
EC (1) | ECSP13012478A (da) |
ES (1) | ES2793723T3 (da) |
GE (1) | GEP20156216B (da) |
HR (1) | HRP20200844T1 (da) |
HU (1) | HUE049460T2 (da) |
IL (1) | IL224452A (da) |
LT (1) | LT2603513T (da) |
MA (1) | MA34509B1 (da) |
MX (1) | MX349470B (da) |
MY (1) | MY165908A (da) |
NZ (1) | NZ607593A (da) |
PE (1) | PE20131116A1 (da) |
PL (1) | PL2603513T3 (da) |
PT (1) | PT2603513T (da) |
RS (1) | RS60311B1 (da) |
SG (1) | SG187656A1 (da) |
SI (1) | SI2603513T1 (da) |
TW (1) | TWI504604B (da) |
UA (1) | UA111594C2 (da) |
UY (1) | UY33551A (da) |
WO (1) | WO2012020848A1 (da) |
ZA (1) | ZA201301120B (da) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20131116A1 (es) * | 2010-08-10 | 2013-10-24 | Takeda Pharmaceutical | Compuestos heterociclicos potenciadores de ampa |
EP2694472B1 (en) * | 2011-04-05 | 2020-03-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
US9493484B2 (en) | 2012-02-08 | 2016-11-15 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
CA2915405A1 (en) * | 2013-06-13 | 2014-12-18 | Veroscience Llc | Compositions and methods for treating metabolic disorders |
DK3013813T3 (da) | 2013-06-27 | 2019-06-03 | Pfizer | Heteroaromatiske forbindelser og anvendelse deraf som dopamin-d1-ligander |
US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
EP3663282B1 (en) | 2013-12-03 | 2022-05-18 | FMC Corporation | Pyrrolidinone herbicides |
EP3164386B1 (en) | 2014-07-02 | 2020-10-07 | FMC Corporation | Piperidinone herbicides |
CN107001260B (zh) | 2014-12-08 | 2020-11-10 | Fmc公司 | 3-氧基-3-(芳氨基)丙酸酯、其制备方法、以及其在制备吡咯烷酮中的用途 |
AU2016246410B2 (en) | 2015-04-10 | 2020-11-05 | Fmc Corporation | Substituted cyclic amides as herbicides |
CN107531658B (zh) | 2015-04-27 | 2021-07-27 | Fmc公司 | 作为除草剂的丁内酯 |
UY36654A (es) * | 2015-04-29 | 2016-10-31 | Janssen Pharmaceutica Nv | Azabenzimidazoles con propiedades moduladoras del receptor ampa y composiciones farmacéuticas que los contienen |
WO2016176457A1 (en) * | 2015-04-29 | 2016-11-03 | Janssen Pharmaceutica Nv | Imidazopyrazines and pyrazolopyrimidines and their use as ampa receptor modulators |
BR112017021859B1 (pt) | 2015-05-12 | 2022-05-10 | Fmc Corporation | Composto, composições herbicidas, mistura herbicida e método para o controle do crescimento de vegetação indesejada |
JP6869192B2 (ja) | 2015-05-29 | 2021-05-12 | エフ エム シー コーポレーションFmc Corporation | 除草剤としての置換環状アミド |
CA2983759A1 (en) | 2015-06-02 | 2016-12-08 | E I Du Pont De Nemours And Company | Substituted cyclic amides and their use as herbicides |
EP3328836B1 (en) | 2015-07-31 | 2021-03-24 | FMC Corporation | Cyclic n-carboxamide compounds useful as herbicides |
TW201713774A (zh) | 2015-08-06 | 2017-04-16 | Kohjin Life Sciences Co Ltd | 含有β-菸鹼醯胺單核苷酸的酵母萃取物及其製造方法 |
KR102579520B1 (ko) * | 2015-08-06 | 2023-09-15 | 에프. 호프만-라 로슈 아게 | Galnac 산 유도체의 제조 방법 |
US20170181292A1 (en) * | 2015-12-16 | 2017-06-22 | Rohm And Haas Electronic Materials Llc | Method for forming organic coating on nickel surface |
CN105669731B (zh) * | 2016-01-10 | 2017-06-30 | 沧州普瑞东方科技有限公司 | 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法 |
ES2958741T3 (es) | 2016-12-21 | 2024-02-14 | Fmc Corp | Herbicidas de nitrona |
CN107892697B (zh) | 2016-12-26 | 2020-11-03 | 郑州泰基鸿诺医药股份有限公司 | 一种[1,3]噻嗪-2-胺类化合物及应用,药物组合物 |
AU2018239935B2 (en) | 2017-03-21 | 2023-05-18 | Fmc Corporation | Pyrrolidinones and a process to prepare them |
EP3599868A4 (en) | 2017-03-21 | 2020-12-02 | FMC Corporation | HERBICIDE MIXTURE, COMPOSITION AND PROCEDURE |
AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
ES2971497T3 (es) | 2017-10-06 | 2024-06-05 | Takeda Pharmaceuticals Co | Compuestos heterocíclicos |
EP3693368B1 (en) * | 2017-10-06 | 2023-12-06 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
WO2021229294A1 (en) | 2020-05-15 | 2021-11-18 | Takeda Pharmaceutical Company Limited | Treatment for depression |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0437742Y2 (da) | 1986-10-22 | 1992-09-04 | ||
JPH0285851A (ja) * | 1988-09-22 | 1990-03-27 | Konica Corp | 新規な写真用カプラー |
JPH037742A (ja) | 1989-06-05 | 1991-01-14 | Toyo Tire & Rubber Co Ltd | ラバーチエーン用ゴム組成物 |
JP2874960B2 (ja) | 1990-06-03 | 1999-03-24 | コニカ株式会社 | 新規な染料を含有するハロゲン化銀写真感光材料 |
JPH04119890A (ja) | 1990-09-11 | 1992-04-21 | Konica Corp | ピラゾロチアジアジン系色素 |
JP3430375B2 (ja) | 1993-11-12 | 2003-07-28 | コニカ株式会社 | 感熱転写材料及び該材料に好適な色素 |
DE19704923A1 (de) | 1997-02-10 | 1998-08-13 | Hoechst Schering Agrevo Gmbh | Klebstoffhaltige Schädlingsbekämpfungsmittel |
JP2003526341A (ja) | 1999-11-04 | 2003-09-09 | コロラド ステート ユニバーシティー リサーチ ファウンデーション | 昆虫を誘引するための装置および方法 |
FR2801587B1 (fr) | 1999-11-30 | 2002-01-11 | Adir | Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
CN1275951C (zh) * | 2001-10-10 | 2006-09-20 | 神经研究公司 | 新的苯并噻嗪衍生物、其制备和应用 |
FR2833955B1 (fr) | 2001-12-21 | 2004-01-30 | Servier Lab | Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2854634B1 (fr) | 2003-05-05 | 2005-07-08 | Servier Lab | Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2865474B1 (fr) | 2004-01-26 | 2008-06-13 | Servier Lab | Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2879201B1 (fr) | 2004-12-10 | 2007-02-16 | Servier Lab | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU2007262661A1 (en) | 2006-06-23 | 2007-12-27 | Nufarm Australia Limited | Phenoxy alkanoate herbicidal composition and method of preparation and use |
EA015600B1 (ru) * | 2006-12-11 | 2011-10-31 | Эли Лилли Энд Компани | Агенты, усиливающие действие амра-рецепторов |
US20080167374A1 (en) | 2007-01-09 | 2008-07-10 | Loveland Products, Inc. | Pesticide composition and method of use |
WO2009061699A1 (en) * | 2007-11-05 | 2009-05-14 | Schering Corporation | Gamma secretase modulators |
JP2011507910A (ja) | 2007-12-21 | 2011-03-10 | ユニバーシティー オブ ロチェスター | 真核生物の寿命を変更するための方法 |
US20110118236A1 (en) | 2008-03-25 | 2011-05-19 | Michiyo Mochizuki | Heterocyclic compound |
JP2009248543A (ja) | 2008-04-11 | 2009-10-29 | Fujifilm Corp | 光情報記録媒体および情報記録方法 |
TW201012803A (en) * | 2008-06-06 | 2010-04-01 | Organon Nv | Heterocyclic derivatives |
US20120129846A1 (en) | 2008-11-06 | 2012-05-24 | Zhaoning Zhu | Gamma secretase modulators |
TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
JP2012051806A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
FR2943342B1 (fr) | 2009-03-20 | 2011-03-04 | Servier Lab | Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
WO2010140339A1 (ja) | 2009-06-01 | 2010-12-09 | 武田薬品工業株式会社 | 複素環化合物 |
EP2455380A4 (en) | 2009-07-13 | 2012-11-28 | Takeda Pharmaceutical | Heterocyclic compound and its use |
WO2011036885A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
WO2011036889A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
PE20131116A1 (es) * | 2010-08-10 | 2013-10-24 | Takeda Pharmaceutical | Compuestos heterociclicos potenciadores de ampa |
-
2011
- 2011-08-09 PE PE2013000244A patent/PE20131116A1/es active IP Right Grant
- 2011-08-09 KR KR1020137006113A patent/KR101852215B1/ko active IP Right Grant
- 2011-08-09 TW TW100128311A patent/TWI504604B/zh active
- 2011-08-09 PT PT117499442T patent/PT2603513T/pt unknown
- 2011-08-09 RS RS20200574A patent/RS60311B1/sr unknown
- 2011-08-09 PL PL11749944T patent/PL2603513T3/pl unknown
- 2011-08-09 SG SG2013007463A patent/SG187656A1/en unknown
- 2011-08-09 NZ NZ607593A patent/NZ607593A/en unknown
- 2011-08-09 MX MX2013001614A patent/MX349470B/es active IP Right Grant
- 2011-08-09 AU AU2011290126A patent/AU2011290126B2/en active Active
- 2011-08-09 AR ARP110102905A patent/AR082618A1/es active IP Right Grant
- 2011-08-09 WO PCT/JP2011/068497 patent/WO2012020848A1/en active Application Filing
- 2011-08-09 EA EA201390222A patent/EA022078B1/ru not_active IP Right Cessation
- 2011-08-09 US US13/206,113 patent/US8575154B2/en active Active
- 2011-08-09 BR BR112013002250-7A patent/BR112013002250B1/pt active IP Right Grant
- 2011-08-09 CN CN201510259936.0A patent/CN104926837A/zh active Pending
- 2011-08-09 UY UY0001033551A patent/UY33551A/es not_active Application Discontinuation
- 2011-08-09 ES ES11749944T patent/ES2793723T3/es active Active
- 2011-08-09 US US13/816,137 patent/US9150591B2/en active Active
- 2011-08-09 DK DK11749944.2T patent/DK2603513T3/da active
- 2011-08-09 MA MA35708A patent/MA34509B1/fr unknown
- 2011-08-09 LT LTEP11749944.2T patent/LT2603513T/lt unknown
- 2011-08-09 GE GEAP201113021A patent/GEP20156216B/en unknown
- 2011-08-09 MY MYPI2013000428A patent/MY165908A/en unknown
- 2011-08-09 JP JP2013506362A patent/JP5788496B2/ja active Active
- 2011-08-09 EP EP11749944.2A patent/EP2603513B1/en active Active
- 2011-08-09 SI SI201131887T patent/SI2603513T1/sl unknown
- 2011-08-09 HU HUE11749944A patent/HUE049460T2/hu unknown
- 2011-08-09 CA CA2807460A patent/CA2807460C/en active Active
- 2011-08-09 CN CN201180048970.3A patent/CN103180326B/zh active Active
- 2011-09-08 UA UAA201302884A patent/UA111594C2/uk unknown
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2013
- 2013-01-28 IL IL224452A patent/IL224452A/en active IP Right Grant
- 2013-02-05 DO DO2013000030A patent/DOP2013000030A/es unknown
- 2013-02-07 CL CL2013000380A patent/CL2013000380A1/es unknown
- 2013-02-12 ZA ZA2013/01120A patent/ZA201301120B/en unknown
- 2013-02-18 CR CR20130066A patent/CR20130066A/es unknown
- 2013-02-22 US US13/774,635 patent/US8778934B2/en active Active
- 2013-02-22 US US13/774,707 patent/US8916551B2/en active Active
- 2013-03-06 EC ECSP13012478 patent/ECSP13012478A/es unknown
- 2013-03-07 CO CO13046020A patent/CO6680700A2/es active IP Right Grant
-
2014
- 2014-11-13 US US14/540,699 patent/US20150073137A1/en not_active Abandoned
-
2015
- 2015-07-21 US US14/804,935 patent/US9499568B2/en active Active
- 2015-07-29 JP JP2015149216A patent/JP6113789B2/ja active Active
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2016
- 2016-10-10 US US15/289,650 patent/US9884875B2/en active Active
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2017
- 2017-12-18 US US15/845,621 patent/US20180162875A1/en not_active Abandoned
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2019
- 2019-01-24 US US16/256,773 patent/US10654874B2/en active Active
-
2020
- 2020-03-23 US US16/827,316 patent/US11279713B2/en active Active
- 2020-05-25 HR HRP20200844TT patent/HRP20200844T1/hr unknown
- 2020-05-25 CY CY20201100475T patent/CY1123507T1/el unknown
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