DK2603513T3 - Heterocyklisk forbindelse og anvendelse deraf som AMPA-receptorpositiv allosterisk modulator - Google Patents

Heterocyklisk forbindelse og anvendelse deraf som AMPA-receptorpositiv allosterisk modulator Download PDF

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Publication number
DK2603513T3
DK2603513T3 DK11749944.2T DK11749944T DK2603513T3 DK 2603513 T3 DK2603513 T3 DK 2603513T3 DK 11749944 T DK11749944 T DK 11749944T DK 2603513 T3 DK2603513 T3 DK 2603513T3
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Denmark
Prior art keywords
heterocyclic compound
positive allosteric
receptor positive
ampa receptor
allosteric modulator
Prior art date
Application number
DK11749944.2T
Other languages
English (en)
Inventor
Masakuni Kori
Shinji Nakamura
Masashi Toyofuku
Eiji Honda
Yasutomi Asano
Michiyo Mochizuki
Toshihiro Imaeda
Osamu Ujikawa
Original Assignee
Takeda Pharmaceuticals Co
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Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
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Publication of DK2603513T3 publication Critical patent/DK2603513T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK11749944.2T 2010-08-10 2011-08-09 Heterocyklisk forbindelse og anvendelse deraf som AMPA-receptorpositiv allosterisk modulator DK2603513T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010179577 2010-08-10
PCT/JP2011/068497 WO2012020848A1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

Publications (1)

Publication Number Publication Date
DK2603513T3 true DK2603513T3 (da) 2020-06-15

Family

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Family Applications (1)

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DK11749944.2T DK2603513T3 (da) 2010-08-10 2011-08-09 Heterocyklisk forbindelse og anvendelse deraf som AMPA-receptorpositiv allosterisk modulator

Country Status (38)

Country Link
US (10) US8575154B2 (da)
EP (1) EP2603513B1 (da)
JP (2) JP5788496B2 (da)
KR (1) KR101852215B1 (da)
CN (2) CN104926837A (da)
AR (1) AR082618A1 (da)
AU (1) AU2011290126B2 (da)
BR (1) BR112013002250B1 (da)
CA (1) CA2807460C (da)
CL (1) CL2013000380A1 (da)
CO (1) CO6680700A2 (da)
CR (1) CR20130066A (da)
CY (1) CY1123507T1 (da)
DK (1) DK2603513T3 (da)
DO (1) DOP2013000030A (da)
EA (1) EA022078B1 (da)
EC (1) ECSP13012478A (da)
ES (1) ES2793723T3 (da)
GE (1) GEP20156216B (da)
HR (1) HRP20200844T1 (da)
HU (1) HUE049460T2 (da)
IL (1) IL224452A (da)
LT (1) LT2603513T (da)
MA (1) MA34509B1 (da)
MX (1) MX349470B (da)
MY (1) MY165908A (da)
NZ (1) NZ607593A (da)
PE (1) PE20131116A1 (da)
PL (1) PL2603513T3 (da)
PT (1) PT2603513T (da)
RS (1) RS60311B1 (da)
SG (1) SG187656A1 (da)
SI (1) SI2603513T1 (da)
TW (1) TWI504604B (da)
UA (1) UA111594C2 (da)
UY (1) UY33551A (da)
WO (1) WO2012020848A1 (da)
ZA (1) ZA201301120B (da)

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Publication number Publication date
US8778934B2 (en) 2014-07-15
EA201390222A1 (ru) 2013-08-30
US10654874B2 (en) 2020-05-19
JP5788496B2 (ja) 2015-09-30
SI2603513T1 (sl) 2020-07-31
UA111594C2 (uk) 2016-05-25
MX349470B (es) 2017-07-31
WO2012020848A1 (en) 2012-02-16
CN103180326B (zh) 2015-06-10
HRP20200844T1 (hr) 2020-08-21
US20150073137A1 (en) 2015-03-12
AU2011290126A1 (en) 2013-03-07
KR20130138738A (ko) 2013-12-19
CN104926837A (zh) 2015-09-23
BR112013002250A2 (pt) 2016-05-24
ES2793723T3 (es) 2020-11-16
CY1123507T1 (el) 2022-03-24
NZ607593A (en) 2015-01-30
PT2603513T (pt) 2020-06-08
AU2011290126B2 (en) 2016-01-07
US20130190291A1 (en) 2013-07-25
US20140080817A1 (en) 2014-03-20
UY33551A (es) 2012-03-30
MX2013001614A (es) 2013-07-05
EP2603513B1 (en) 2020-03-11
LT2603513T (lt) 2020-05-25
US8916551B2 (en) 2014-12-23
US20130184266A1 (en) 2013-07-18
JP2013535408A (ja) 2013-09-12
US20190263832A1 (en) 2019-08-29
MY165908A (en) 2018-05-18
JP2016006080A (ja) 2016-01-14
EA022078B1 (ru) 2015-10-30
ECSP13012478A (es) 2013-04-30
AR082618A1 (es) 2012-12-19
CL2013000380A1 (es) 2013-05-31
CA2807460A1 (en) 2012-02-16
PE20131116A1 (es) 2013-10-24
JP6113789B2 (ja) 2017-04-12
US8575154B2 (en) 2013-11-05
SG187656A1 (en) 2013-03-28
US9150591B2 (en) 2015-10-06
BR112013002250B1 (pt) 2020-10-27
US20120077799A1 (en) 2012-03-29
HUE049460T2 (hu) 2020-09-28
MA34509B1 (fr) 2013-09-02
KR101852215B1 (ko) 2018-04-25
CN103180326A (zh) 2013-06-26
CA2807460C (en) 2018-09-18
RS60311B1 (sr) 2020-07-31
US20180162875A1 (en) 2018-06-14
US11279713B2 (en) 2022-03-22
US9884875B2 (en) 2018-02-06
US9499568B2 (en) 2016-11-22
DOP2013000030A (es) 2013-03-15
TW201217386A (en) 2012-05-01
US20170022222A1 (en) 2017-01-26
CO6680700A2 (es) 2013-05-31
IL224452A (en) 2017-11-30
CR20130066A (es) 2013-05-03
TWI504604B (zh) 2015-10-21
ZA201301120B (en) 2014-04-30
PL2603513T3 (pl) 2020-07-27
WO2012020848A8 (en) 2012-09-27
US20150353578A1 (en) 2015-12-10
GEP20156216B (en) 2015-01-12
EP2603513A1 (en) 2013-06-19
US20200317692A1 (en) 2020-10-08

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