HUE049460T2 - Heterociklusos vegyület és annak alkalmazása ampa receptor pozitív allosztérikus modulátorként - Google Patents
Heterociklusos vegyület és annak alkalmazása ampa receptor pozitív allosztérikus modulátorkéntInfo
- Publication number
- HUE049460T2 HUE049460T2 HUE11749944A HUE11749944A HUE049460T2 HU E049460 T2 HUE049460 T2 HU E049460T2 HU E11749944 A HUE11749944 A HU E11749944A HU E11749944 A HUE11749944 A HU E11749944A HU E049460 T2 HUE049460 T2 HU E049460T2
- Authority
- HU
- Hungary
- Prior art keywords
- heterocyclic compound
- positive allosteric
- receptor positive
- ampa receptor
- allosteric modulator
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010179577 | 2010-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE049460T2 true HUE049460T2 (hu) | 2020-09-28 |
Family
ID=44534564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE11749944A HUE049460T2 (hu) | 2010-08-10 | 2011-08-09 | Heterociklusos vegyület és annak alkalmazása ampa receptor pozitív allosztérikus modulátorként |
Country Status (38)
| Country | Link |
|---|---|
| US (11) | US9150591B2 (hu) |
| EP (1) | EP2603513B1 (hu) |
| JP (2) | JP5788496B2 (hu) |
| KR (1) | KR101852215B1 (hu) |
| CN (2) | CN103180326B (hu) |
| AR (1) | AR082618A1 (hu) |
| AU (1) | AU2011290126B2 (hu) |
| BR (1) | BR112013002250B1 (hu) |
| CA (1) | CA2807460C (hu) |
| CL (1) | CL2013000380A1 (hu) |
| CO (1) | CO6680700A2 (hu) |
| CR (1) | CR20130066A (hu) |
| CY (1) | CY1123507T1 (hu) |
| DK (1) | DK2603513T3 (hu) |
| DO (1) | DOP2013000030A (hu) |
| EA (1) | EA022078B1 (hu) |
| EC (1) | ECSP13012478A (hu) |
| ES (1) | ES2793723T3 (hu) |
| GE (1) | GEP20156216B (hu) |
| HR (1) | HRP20200844T1 (hu) |
| HU (1) | HUE049460T2 (hu) |
| IL (1) | IL224452A (hu) |
| LT (1) | LT2603513T (hu) |
| MA (1) | MA34509B1 (hu) |
| MX (1) | MX349470B (hu) |
| MY (1) | MY165908A (hu) |
| NZ (1) | NZ607593A (hu) |
| PE (1) | PE20131116A1 (hu) |
| PL (1) | PL2603513T3 (hu) |
| PT (1) | PT2603513T (hu) |
| RS (1) | RS60311B1 (hu) |
| SG (1) | SG187656A1 (hu) |
| SI (1) | SI2603513T1 (hu) |
| TW (1) | TWI504604B (hu) |
| UA (1) | UA111594C2 (hu) |
| UY (1) | UY33551A (hu) |
| WO (1) | WO2012020848A1 (hu) |
| ZA (1) | ZA201301120B (hu) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9150591B2 (en) * | 2010-08-10 | 2015-10-06 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
| US9527807B2 (en) | 2011-04-05 | 2016-12-27 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
| EP2813508B1 (en) * | 2012-02-08 | 2018-01-31 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
| CA2915405A1 (en) * | 2013-06-13 | 2014-12-18 | Veroscience Llc | Compositions and methods for treating metabolic disorders |
| BR122023004130B1 (pt) | 2013-06-27 | 2023-12-12 | Pfizer Inc | Compostos heteroaromáticos, composição farmacêutica e uso dos referidos compostos no tratamento de distúrbios mediados ou associados a dopamina d1 |
| SI3663282T1 (sl) | 2013-12-03 | 2022-08-31 | Fmc Corporation | Pirolidinonski herbicidi |
| US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
| SG11201610720VA (en) | 2014-07-02 | 2017-01-27 | Du Pont | Piperidinone herbicides |
| SG11201702924WA (en) | 2014-12-08 | 2017-05-30 | Du Pont | 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones |
| CN107466290B (zh) | 2015-04-10 | 2021-08-03 | Fmc公司 | 作为除草剂的取代的环酰胺 |
| AU2016254958B2 (en) | 2015-04-27 | 2020-04-23 | Fmc Corporation | Butyrolactones as herbicides |
| US10513523B2 (en) * | 2015-04-29 | 2019-12-24 | Janssen Pharmaceutica Nv | Imidazopyrazines and pyrazolopyrimidines and their use as AMPA receptor modulators |
| CN107835814B (zh) * | 2015-04-29 | 2021-07-23 | 詹森药业有限公司 | 氮杂苯并咪唑及其作为ampa受体调节剂的用途 |
| JP7000160B2 (ja) | 2015-05-12 | 2022-01-19 | エフ エム シー コーポレーション | 除草剤としてのアリール置換二環式化合物 |
| CN107690426B (zh) | 2015-05-29 | 2021-07-06 | Fmc公司 | 作为除草剂的取代的环酰胺 |
| WO2016196593A1 (en) | 2015-06-02 | 2016-12-08 | E I Du Pont De Nemours And Company | Substituted cyclic amides and their use as herbicides |
| RU2720994C2 (ru) | 2015-07-31 | 2020-05-15 | Е.И.Дюпон Де Немур Энд Компани | Новые соединения циклического n-карбоксамида, применяемые в качестве гербицидов |
| TW201713774A (zh) | 2015-08-06 | 2017-04-16 | Kohjin Life Sciences Co Ltd | 含有β-菸鹼醯胺單核苷酸的酵母萃取物及其製造方法 |
| CN107709342B (zh) * | 2015-08-06 | 2021-09-03 | 豪夫迈·罗氏有限公司 | 制备乙酰半乳糖胺酸衍生物的方法 |
| US20170181292A1 (en) * | 2015-12-16 | 2017-06-22 | Rohm And Haas Electronic Materials Llc | Method for forming organic coating on nickel surface |
| CN105669731B (zh) * | 2016-01-10 | 2017-06-30 | 沧州普瑞东方科技有限公司 | 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法 |
| RU2019122791A (ru) | 2016-12-21 | 2021-01-25 | Фмк Корпорейшн | Гербициды на основе нитрона |
| CN107892697B (zh) | 2016-12-26 | 2020-11-03 | 郑州泰基鸿诺医药股份有限公司 | 一种[1,3]噻嗪-2-胺类化合物及应用，药物组合物 |
| KR102620213B1 (ko) | 2017-03-21 | 2024-01-03 | 에프엠씨 코포레이션 | 피롤리디논 및 이의 제조 방법 |
| MX2019011090A (es) | 2017-03-21 | 2019-11-18 | Fmc Corp | Mezcla herbicida, composición y método. |
| AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
| AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
| WO2019070043A1 (ja) | 2017-10-06 | 2019-04-11 | 武田薬品工業株式会社 | 複素環化合物 |
| JP7250687B2 (ja) | 2017-10-06 | 2023-04-03 | 武田薬品工業株式会社 | 複素環化合物 |
| JP2023526249A (ja) * | 2020-05-15 | 2023-06-21 | 武田薬品工業株式会社 | うつ病の処置 |
| CN113943294A (zh) * | 2020-07-15 | 2022-01-18 | 成都海博为药业有限公司 | 一种作为btk抑制剂的化合物及其制备方法与用途 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0437742Y2 (hu) | 1986-10-22 | 1992-09-04 | ||
| JPH0285851A (ja) * | 1988-09-22 | 1990-03-27 | Konica Corp | 新規な写真用カプラー |
| JPH037742A (ja) | 1989-06-05 | 1991-01-14 | Toyo Tire & Rubber Co Ltd | ラバーチエーン用ゴム組成物 |
| JP2874960B2 (ja) * | 1990-06-03 | 1999-03-24 | コニカ株式会社 | 新規な染料を含有するハロゲン化銀写真感光材料 |
| JPH04119890A (ja) | 1990-09-11 | 1992-04-21 | Konica Corp | ピラゾロチアジアジン系色素 |
| JP3430375B2 (ja) | 1993-11-12 | 2003-07-28 | コニカ株式会社 | 感熱転写材料及び該材料に好適な色素 |
| DE19704923A1 (de) | 1997-02-10 | 1998-08-13 | Hoechst Schering Agrevo Gmbh | Klebstoffhaltige Schädlingsbekämpfungsmittel |
| WO2001032013A1 (en) | 1999-11-04 | 2001-05-10 | Colorado State University Research Foundation | Method and device for attracting insects |
| FR2801587B1 (fr) | 1999-11-30 | 2002-01-11 | Adir | Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2458388A1 (en) * | 2001-10-10 | 2003-04-17 | Neurosearch A/S | Novel benzothiazine derivatives, their preparation and use |
| FR2833955B1 (fr) * | 2001-12-21 | 2004-01-30 | Servier Lab | Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2854634B1 (fr) * | 2003-05-05 | 2005-07-08 | Servier Lab | Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2865474B1 (fr) | 2004-01-26 | 2008-06-13 | Servier Lab | Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2879201B1 (fr) * | 2004-12-10 | 2007-02-16 | Servier Lab | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2655376A1 (en) | 2006-06-23 | 2007-12-27 | Nufarm Australia Limited | Phenoxy alkanoate herbicidal composition and method of preparation and use |
| EA015600B1 (ru) * | 2006-12-11 | 2011-10-31 | Эли Лилли Энд Компани | Агенты, усиливающие действие амра-рецепторов |
| US20080167374A1 (en) | 2007-01-09 | 2008-07-10 | Loveland Products, Inc. | Pesticide composition and method of use |
| CN101910178A (zh) * | 2007-11-05 | 2010-12-08 | 先灵公司 | γ分泌酶调节剂 |
| US8642660B2 (en) * | 2007-12-21 | 2014-02-04 | The University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| JPWO2009119088A1 (ja) | 2008-03-25 | 2011-07-21 | 武田薬品工業株式会社 | 複素環化合物 |
| JP2009248543A (ja) * | 2008-04-11 | 2009-10-29 | Fujifilm Corp | 光情報記録媒体および情報記録方法 |
| TW201012803A (en) | 2008-06-06 | 2010-04-01 | Organon Nv | Heterocyclic derivatives |
| WO2010054078A1 (en) * | 2008-11-06 | 2010-05-14 | Schering Corporation | Gamma secretase modulators |
| TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
| JP2012051806A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
| FR2943342B1 (fr) | 2009-03-20 | 2011-03-04 | Servier Lab | Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO2010140339A1 (ja) | 2009-06-01 | 2010-12-09 | 武田薬品工業株式会社 | 複素環化合物 |
| WO2011007756A1 (ja) | 2009-07-13 | 2011-01-20 | 武田薬品工業株式会社 | 複素環化合物及びその用途 |
| WO2011036885A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| WO2011036889A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| US9150591B2 (en) * | 2010-08-10 | 2015-10-06 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
-
2011
- 2011-08-09 US US13/816,137 patent/US9150591B2/en active Active
- 2011-08-09 PE PE2013000244A patent/PE20131116A1/es active IP Right Grant
- 2011-08-09 PT PT117499442T patent/PT2603513T/pt unknown
- 2011-08-09 MY MYPI2013000428A patent/MY165908A/en unknown
- 2011-08-09 AR ARP110102905A patent/AR082618A1/es active IP Right Grant
- 2011-08-09 SI SI201131887T patent/SI2603513T1/sl unknown
- 2011-08-09 WO PCT/JP2011/068497 patent/WO2012020848A1/en active Application Filing
- 2011-08-09 CN CN201180048970.3A patent/CN103180326B/zh active Active
- 2011-08-09 AU AU2011290126A patent/AU2011290126B2/en active Active
- 2011-08-09 DK DK11749944.2T patent/DK2603513T3/da active
- 2011-08-09 BR BR112013002250-7A patent/BR112013002250B1/pt active IP Right Grant
- 2011-08-09 ES ES11749944T patent/ES2793723T3/es active Active
- 2011-08-09 CN CN201510259936.0A patent/CN104926837A/zh active Pending
- 2011-08-09 CA CA2807460A patent/CA2807460C/en active Active
- 2011-08-09 US US13/206,113 patent/US8575154B2/en active Active
- 2011-08-09 GE GEAP201113021A patent/GEP20156216B/en unknown
- 2011-08-09 MA MA35708A patent/MA34509B1/fr unknown
- 2011-08-09 EP EP11749944.2A patent/EP2603513B1/en active Active
- 2011-08-09 KR KR1020137006113A patent/KR101852215B1/ko active IP Right Grant
- 2011-08-09 SG SG2013007463A patent/SG187656A1/en unknown
- 2011-08-09 NZ NZ607593A patent/NZ607593A/en unknown
- 2011-08-09 MX MX2013001614A patent/MX349470B/es active IP Right Grant
- 2011-08-09 UY UY0001033551A patent/UY33551A/es not_active Application Discontinuation
- 2011-08-09 TW TW100128311A patent/TWI504604B/zh active
- 2011-08-09 JP JP2013506362A patent/JP5788496B2/ja active Active
- 2011-08-09 EA EA201390222A patent/EA022078B1/ru not_active IP Right Cessation
- 2011-08-09 HU HUE11749944A patent/HUE049460T2/hu unknown
- 2011-08-09 RS RS20200574A patent/RS60311B1/sr unknown
- 2011-08-09 PL PL11749944T patent/PL2603513T3/pl unknown
- 2011-08-09 LT LTEP11749944.2T patent/LT2603513T/lt unknown
- 2011-09-08 UA UAA201302884A patent/UA111594C2/uk unknown
-
2013
- 2013-01-28 IL IL224452A patent/IL224452A/en active IP Right Grant
- 2013-02-05 DO DO2013000030A patent/DOP2013000030A/es unknown
- 2013-02-07 CL CL2013000380A patent/CL2013000380A1/es unknown
- 2013-02-12 ZA ZA2013/01120A patent/ZA201301120B/en unknown
- 2013-02-18 CR CR20130066A patent/CR20130066A/es unknown
- 2013-02-22 US US13/774,635 patent/US8778934B2/en active Active
- 2013-02-22 US US13/774,707 patent/US8916551B2/en active Active
- 2013-03-06 EC ECSP13012478 patent/ECSP13012478A/es unknown
- 2013-03-07 CO CO13046020A patent/CO6680700A2/es active IP Right Grant
-
2014
- 2014-11-13 US US14/540,699 patent/US20150073137A1/en not_active Abandoned
-
2015
- 2015-07-21 US US14/804,935 patent/US9499568B2/en active Active
- 2015-07-29 JP JP2015149216A patent/JP6113789B2/ja active Active
-
2016
- 2016-10-10 US US15/289,650 patent/US9884875B2/en active Active
-
2017
- 2017-12-18 US US15/845,621 patent/US20180162875A1/en not_active Abandoned
-
2019
- 2019-01-24 US US16/256,773 patent/US10654874B2/en active Active
-
2020
- 2020-03-23 US US16/827,316 patent/US11279713B2/en active Active
- 2020-05-25 HR HRP20200844TT patent/HRP20200844T1/hr unknown
- 2020-05-25 CY CY20201100475T patent/CY1123507T1/el unknown
-
2024
- 2024-03-01 US US18/592,897 patent/US20240360156A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| LT2603513T (lt) | Heterociklinis junginys ir jo panaudojimas kaip ampa receptoriaus teigiamo alosterinio moduliatoriaus | |
| IL246600B (en) | Heterocyclic compounds and their use | |
| IL222288A0 (en) | Heterocyclic compounds and their uses | |
| EP2637669A4 (en) | Heterocyclic compounds and their use | |
| IL225770A0 (en) | Heterocyclic compounds | |
| EP2575462A4 (en) | Heterocyclic compounds and their use | |
| IL221442A0 (en) | Heterocyclic compound | |
| EP2579717A4 (en) | POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 | |
| EP2603079A4 (en) | POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 | |
| ZA201300950B (en) | Heterocyclic compound | |
| EP2542083A4 (en) | POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 | |
| EP2604597A4 (en) | HETEROCYCLIC COMPOUND AND USE THEREOF | |
| EP2582241A4 (en) | HETEROCYCLIC FUSIONED PHENANTHROLINONE COMPOUNDS USEFUL AS POSITIVE ALLOSERIC MODULATORS OF THE M1 RECEPTOR | |
| EP2563126A4 (en) | POSITIVE ALLOSTERIC MODULATORS OF M1 RECEPTOR DERIVED FROM HETEROCYCLIC QUINOLIZINE | |
| ZA201306586B (en) | Thynyl derivatives as positive allosteric modulators of the mglur5 | |
| ZA201300157B (en) | Fused heterocyclic derivatives as s1p modulators | |
| EP2597095A4 (en) | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | |
| EP2583965A4 (en) | HETEROCYCLIC RING CONNECTION | |
| GB2477949B (en) | Powering of devices | |
| PL2769720T3 (pl) | Heterocykliczne allosteryczne modulatory gsk-3 | |
| GB201021416D0 (en) | Novel heterocyclic compounds | |
| GB201009514D0 (en) | Novel heterocyclic compounds |