PL2769720T3 - Heterocykliczne allosteryczne modulatory gsk-3 - Google Patents
Heterocykliczne allosteryczne modulatory gsk-3Info
- Publication number
- PL2769720T3 PL2769720T3 PL12836243T PL12836243T PL2769720T3 PL 2769720 T3 PL2769720 T3 PL 2769720T3 PL 12836243 T PL12836243 T PL 12836243T PL 12836243 T PL12836243 T PL 12836243T PL 2769720 T3 PL2769720 T3 PL 2769720T3
- Authority
- PL
- Poland
- Prior art keywords
- gsk
- heterocyclic
- allosteric modulators
- allosteric
- modulators
- Prior art date
Links
- 230000003281 allosteric effect Effects 0.000 title 1
- 101150090422 gsk-3 gene Proteins 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201131582A ES2402503B1 (es) | 2011-09-30 | 2011-09-30 | Moduladores alostéricos de gsk-3 de naturaleza heterocíclica. |
| EP12836243.1A EP2769720B1 (en) | 2011-09-30 | 2012-09-28 | Heterocyclic gsk-3 allosteric modulators |
| PCT/ES2012/070672 WO2013045736A1 (es) | 2011-09-30 | 2012-09-28 | Moduladores alostéricos de gsk-3 de naturaleza heterocíclica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2769720T3 true PL2769720T3 (pl) | 2017-12-29 |
Family
ID=47994332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12836243T PL2769720T3 (pl) | 2011-09-30 | 2012-09-28 | Heterocykliczne allosteryczne modulatory gsk-3 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9193688B2 (pl) |
| EP (1) | EP2769720B1 (pl) |
| AU (1) | AU2012314283B2 (pl) |
| DK (1) | DK2769720T3 (pl) |
| ES (2) | ES2402503B1 (pl) |
| PL (1) | PL2769720T3 (pl) |
| WO (1) | WO2013045736A1 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4094764A1 (en) | 2021-05-24 | 2022-11-30 | Consejo Superior De Investigaciones Científicas | 1,2-dihydroquinoline-2-ones for their use in the treatment of limb-girdle muscular dystrophy |
| AU2022391025A1 (en) | 2021-11-19 | 2024-06-06 | The Brigham And Women's Hospital, Inc. | Bifunctional chimeric molecules for labeling of kinases with target binding moieties and methods of use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008518964A (ja) * | 2004-11-01 | 2008-06-05 | ユニバーシティ オブ サザン カリフォルニア | 癌と、血管新生機能に関連する疾患との治療用新規化合物 |
| AU2007225088B2 (en) * | 2006-03-13 | 2012-09-13 | Kyorin Pharmaceutical Co., Ltd | Aminoquinolones as GSK-3 inhibitors |
| EP2059305A2 (en) * | 2006-07-26 | 2009-05-20 | Novartis Ag | Inhibitors of undecaprenyl pyrophosphate synthase |
-
2011
- 2011-09-30 ES ES201131582A patent/ES2402503B1/es not_active Expired - Fee Related
-
2012
- 2012-09-28 EP EP12836243.1A patent/EP2769720B1/en active Active
- 2012-09-28 AU AU2012314283A patent/AU2012314283B2/en active Active
- 2012-09-28 US US14/348,277 patent/US9193688B2/en active Active
- 2012-09-28 PL PL12836243T patent/PL2769720T3/pl unknown
- 2012-09-28 WO PCT/ES2012/070672 patent/WO2013045736A1/es not_active Ceased
- 2012-09-28 DK DK12836243.1T patent/DK2769720T3/en active
- 2012-09-28 ES ES12836243.1T patent/ES2635427T3/es active Active
-
2015
- 2015-10-22 US US14/920,030 patent/US9585879B2/en active Active
-
2017
- 2017-01-25 US US15/415,188 patent/US9757369B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9757369B2 (en) | 2017-09-12 |
| AU2012314283B2 (en) | 2017-04-27 |
| US20160113918A1 (en) | 2016-04-28 |
| EP2769720B1 (en) | 2017-03-29 |
| US20150057311A1 (en) | 2015-02-26 |
| US9193688B2 (en) | 2015-11-24 |
| DK2769720T3 (en) | 2017-07-17 |
| WO2013045736A1 (es) | 2013-04-04 |
| AU2012314283A1 (en) | 2014-05-22 |
| EP2769720A4 (en) | 2015-05-20 |
| ES2402503A1 (es) | 2013-05-06 |
| EP2769720A1 (en) | 2014-08-27 |
| US9585879B2 (en) | 2017-03-07 |
| US20170196850A1 (en) | 2017-07-13 |
| ES2635427T3 (es) | 2017-10-03 |
| ES2402503B1 (es) | 2014-04-04 |
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