PL2603513T3 - Heterocykliczny związek i jego zastosowanie jako pozytywny modulator allosteryczny receptora AMPA - Google Patents

Heterocykliczny związek i jego zastosowanie jako pozytywny modulator allosteryczny receptora AMPA

Info

Publication number
PL2603513T3
PL2603513T3 PL11749944T PL11749944T PL2603513T3 PL 2603513 T3 PL2603513 T3 PL 2603513T3 PL 11749944 T PL11749944 T PL 11749944T PL 11749944 T PL11749944 T PL 11749944T PL 2603513 T3 PL2603513 T3 PL 2603513T3
Authority
PL
Poland
Prior art keywords
heterocyclic compound
positive allosteric
receptor positive
ampa receptor
allosteric modulator
Prior art date
Application number
PL11749944T
Other languages
English (en)
Inventor
Masakuni Kori
Toshihiro Imaeda
Shinji Nakamura
Masashi Toyofuku
Eiji Honda
Yasutomi Asano
Osamu Ujikawa
Michiyo Mochizuki
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of PL2603513T3 publication Critical patent/PL2603513T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
PL11749944T 2010-08-10 2011-08-09 Heterocykliczny związek i jego zastosowanie jako pozytywny modulator allosteryczny receptora AMPA PL2603513T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010179577 2010-08-10
EP11749944.2A EP2603513B1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof as ampa receptor positive allosteric modulator
PCT/JP2011/068497 WO2012020848A1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

Publications (1)

Publication Number Publication Date
PL2603513T3 true PL2603513T3 (pl) 2020-07-27

Family

ID=44534564

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11749944T PL2603513T3 (pl) 2010-08-10 2011-08-09 Heterocykliczny związek i jego zastosowanie jako pozytywny modulator allosteryczny receptora AMPA

Country Status (39)

Country Link
US (11) US8575154B2 (pl)
EP (1) EP2603513B1 (pl)
JP (2) JP5788496B2 (pl)
KR (1) KR101852215B1 (pl)
CN (2) CN103180326B (pl)
AR (1) AR082618A1 (pl)
AU (1) AU2011290126B2 (pl)
BR (1) BR112013002250B1 (pl)
CA (1) CA2807460C (pl)
CL (1) CL2013000380A1 (pl)
CO (1) CO6680700A2 (pl)
CR (1) CR20130066A (pl)
CY (1) CY1123507T1 (pl)
DK (1) DK2603513T3 (pl)
DO (1) DOP2013000030A (pl)
EA (1) EA022078B1 (pl)
EC (1) ECSP13012478A (pl)
ES (1) ES2793723T3 (pl)
GE (1) GEP20156216B (pl)
HR (1) HRP20200844T1 (pl)
HU (1) HUE049460T2 (pl)
IL (1) IL224452A (pl)
LT (1) LT2603513T (pl)
MA (1) MA34509B1 (pl)
MX (1) MX349470B (pl)
MY (1) MY165908A (pl)
NZ (1) NZ607593A (pl)
PE (1) PE20131116A1 (pl)
PH (1) PH12013500247A1 (pl)
PL (1) PL2603513T3 (pl)
PT (1) PT2603513T (pl)
RS (1) RS60311B1 (pl)
SG (1) SG187656A1 (pl)
SI (1) SI2603513T1 (pl)
TW (1) TWI504604B (pl)
UA (1) UA111594C2 (pl)
UY (1) UY33551A (pl)
WO (1) WO2012020848A1 (pl)
ZA (1) ZA201301120B (pl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR082618A1 (es) * 2010-08-10 2012-12-19 Takeda Pharmaceutical Derivados de tiadiazina, composiciones farmaceuticas y usos
JP5976011B2 (ja) * 2011-04-05 2016-08-23 武田薬品工業株式会社 スルホンアミド誘導体およびその用途
EP2813508B1 (en) * 2012-02-08 2018-01-31 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
US20150011554A1 (en) * 2013-06-13 2015-01-08 Veroscience Llc Compositions and Methods for Treating Metabolic Disorders
TN2015000547A1 (fr) 2013-06-27 2017-04-06 Pfizer Composes heteroaromatiques et leur utilisation comme ligands de dopamine d1
US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
CA2931961C (en) 2013-12-03 2023-10-31 Andrew Duncan Satterfield Pyrrolidinones as herbicides
MX389921B (es) 2014-07-02 2025-03-20 Fmc Corp Star Herbicidas de piperidinona.
JP6611816B2 (ja) 2014-12-08 2019-11-27 エフ エム シー コーポレーション 3−オキソ−3−(アリールアミノ)プロパノエイト、その製造方法、およびピロリジノンの製造におけるその使用
AU2016246410B2 (en) 2015-04-10 2020-11-05 Fmc Corporation Substituted cyclic amides as herbicides
RU2734932C2 (ru) 2015-04-27 2020-10-26 ЭфЭмСи Корпорейшн Бутиролактоны в качестве гербицидов
HUE053943T2 (hu) 2015-04-29 2021-08-30 Janssen Pharmaceutica Nv Azabenzimidazolok és ampa receptor modulátorokként való alkalmazásuk
CN107567452B (zh) * 2015-04-29 2020-07-07 詹森药业有限公司 咪唑并哌嗪和吡唑并嘧啶以及它们作为ampa受体调节剂的用途
CA2980643C (en) 2015-05-12 2023-10-17 E I Du Pont De Nemours And Company Aryl substituted bicyclic compounds as herbicides
EP3303287B1 (en) 2015-05-29 2020-12-16 FMC Corporation Substituted cyclic amides as herbicides
JP6949730B2 (ja) 2015-06-02 2021-10-13 エフ エム シー コーポレーションFmc Corporation 置換環状アミドおよび除草剤としてのそれらの使用
RU2720994C2 (ru) 2015-07-31 2020-05-15 Е.И.Дюпон Де Немур Энд Компани Новые соединения циклического n-карбоксамида, применяемые в качестве гербицидов
SI3331892T1 (sl) * 2015-08-06 2019-10-30 Hoffmann La Roche Postopki za pripravo derivatov gaINAc kisline
US20170181292A1 (en) * 2015-12-16 2017-06-22 Rohm And Haas Electronic Materials Llc Method for forming organic coating on nickel surface
CN105669731B (zh) * 2016-01-10 2017-06-30 沧州普瑞东方科技有限公司 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法
ES2958741T3 (es) 2016-12-21 2024-02-14 Fmc Corp Herbicidas de nitrona
CN107892697B (zh) 2016-12-26 2020-11-03 郑州泰基鸿诺医药股份有限公司 一种[1,3]噻嗪-2-胺类化合物及应用,药物组合物
UA126576C2 (uk) 2017-03-21 2022-11-02 ЕфЕмСі КОРПОРЕЙШН Гербіцидна суміш, композиція та спосіб
KR102620213B1 (ko) 2017-03-21 2024-01-03 에프엠씨 코포레이션 피롤리디논 및 이의 제조 방법
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
WO2019070043A1 (ja) 2017-10-06 2019-04-11 武田薬品工業株式会社 複素環化合物
EP3693360B1 (en) * 2017-10-06 2023-12-13 Takeda Pharmaceutical Company Limited Heterocyclic compounds
US12370192B2 (en) 2019-09-16 2025-07-29 Takeda Pharmaceutical Company Limited Azole-fused pyridazin-3(2H)-one derivatives
TW202207944A (zh) * 2020-05-15 2022-03-01 日商武田藥品工業股份有限公司 抑鬱症之治療
CN113943294A (zh) * 2020-07-15 2022-01-18 成都海博为药业有限公司 一种作为btk抑制剂的化合物及其制备方法与用途
WO2025226581A1 (en) 2024-04-22 2025-10-30 Neurocrine Biosciences, Inc. Osavampator for use in the treatment of depressive disorders and cognitive impairment

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0437742Y2 (pl) 1986-10-22 1992-09-04
JPH0285851A (ja) * 1988-09-22 1990-03-27 Konica Corp 新規な写真用カプラー
JPH037742A (ja) 1989-06-05 1991-01-14 Toyo Tire & Rubber Co Ltd ラバーチエーン用ゴム組成物
JP2874960B2 (ja) * 1990-06-03 1999-03-24 コニカ株式会社 新規な染料を含有するハロゲン化銀写真感光材料
JPH04119890A (ja) 1990-09-11 1992-04-21 Konica Corp ピラゾロチアジアジン系色素
JP3430375B2 (ja) 1993-11-12 2003-07-28 コニカ株式会社 感熱転写材料及び該材料に好適な色素
DE19704923A1 (de) 1997-02-10 1998-08-13 Hoechst Schering Agrevo Gmbh Klebstoffhaltige Schädlingsbekämpfungsmittel
EP1229786A1 (en) 1999-11-04 2002-08-14 Colorado State University Method and device for attracting insects
FR2801587B1 (fr) 1999-11-30 2002-01-11 Adir Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2458388A1 (en) 2001-10-10 2003-04-17 Neurosearch A/S Novel benzothiazine derivatives, their preparation and use
FR2833955B1 (fr) 2001-12-21 2004-01-30 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2854634B1 (fr) 2003-05-05 2005-07-08 Servier Lab Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2865474B1 (fr) 2004-01-26 2008-06-13 Servier Lab Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2007262661A1 (en) 2006-06-23 2007-12-27 Nufarm Australia Limited Phenoxy alkanoate herbicidal composition and method of preparation and use
AU2007333247B2 (en) * 2006-12-11 2012-06-07 Eli Lilly And Company AMPA receptor potentiators
US20080167374A1 (en) 2007-01-09 2008-07-10 Loveland Products, Inc. Pesticide composition and method of use
CN101910178A (zh) 2007-11-05 2010-12-08 先灵公司 γ分泌酶调节剂
JP2011507910A (ja) * 2007-12-21 2011-03-10 ユニバーシティー オブ ロチェスター 真核生物の寿命を変更するための方法
JPWO2009119088A1 (ja) 2008-03-25 2011-07-21 武田薬品工業株式会社 複素環化合物
JP2009248543A (ja) * 2008-04-11 2009-10-29 Fujifilm Corp 光情報記録媒体および情報記録方法
TW201012803A (en) * 2008-06-06 2010-04-01 Organon Nv Heterocyclic derivatives
WO2010054078A1 (en) 2008-11-06 2010-05-14 Schering Corporation Gamma secretase modulators
TW201030002A (en) 2009-01-16 2010-08-16 Bristol Myers Squibb Co Bicyclic compounds for the reduction of beta-amyloid production
JP2012051806A (ja) 2009-02-26 2012-03-15 Eisai R & D Management Co Ltd イミダゾリルピラジン誘導体
FR2943342B1 (fr) 2009-03-20 2011-03-04 Servier Lab Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
WO2010140339A1 (ja) 2009-06-01 2010-12-09 武田薬品工業株式会社 複素環化合物
CA2767764A1 (en) 2009-07-13 2011-01-20 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
WO2011036889A1 (ja) 2009-09-25 2011-03-31 武田薬品工業株式会社 複素環化合物
WO2011036885A1 (ja) 2009-09-25 2011-03-31 武田薬品工業株式会社 複素環化合物
AR082618A1 (es) * 2010-08-10 2012-12-19 Takeda Pharmaceutical Derivados de tiadiazina, composiciones farmaceuticas y usos

Also Published As

Publication number Publication date
AU2011290126A1 (en) 2013-03-07
BR112013002250B1 (pt) 2020-10-27
PE20131116A1 (es) 2013-10-24
US8575154B2 (en) 2013-11-05
HUE049460T2 (hu) 2020-09-28
LT2603513T (lt) 2020-05-25
KR20130138738A (ko) 2013-12-19
IL224452A (en) 2017-11-30
AU2011290126B2 (en) 2016-01-07
DK2603513T3 (da) 2020-06-15
US8778934B2 (en) 2014-07-15
EA022078B1 (ru) 2015-10-30
WO2012020848A1 (en) 2012-02-16
MA34509B1 (fr) 2013-09-02
CA2807460A1 (en) 2012-02-16
BR112013002250A2 (pt) 2016-05-24
US20170022222A1 (en) 2017-01-26
ES2793723T3 (es) 2020-11-16
CA2807460C (en) 2018-09-18
US9150591B2 (en) 2015-10-06
US20180162875A1 (en) 2018-06-14
US20200317692A1 (en) 2020-10-08
CN103180326B (zh) 2015-06-10
US9499568B2 (en) 2016-11-22
JP2016006080A (ja) 2016-01-14
EP2603513A1 (en) 2013-06-19
US11279713B2 (en) 2022-03-22
JP2013535408A (ja) 2013-09-12
JP6113789B2 (ja) 2017-04-12
SI2603513T1 (sl) 2020-07-31
UA111594C2 (uk) 2016-05-25
RS60311B1 (sr) 2020-07-31
US20140080817A1 (en) 2014-03-20
US20150073137A1 (en) 2015-03-12
PT2603513T (pt) 2020-06-08
EA201390222A1 (ru) 2013-08-30
CO6680700A2 (es) 2013-05-31
NZ607593A (en) 2015-01-30
US8916551B2 (en) 2014-12-23
US9884875B2 (en) 2018-02-06
WO2012020848A8 (en) 2012-09-27
TW201217386A (en) 2012-05-01
MY165908A (en) 2018-05-18
AR082618A1 (es) 2012-12-19
KR101852215B1 (ko) 2018-04-25
CN104926837A (zh) 2015-09-23
ECSP13012478A (es) 2013-04-30
US20150353578A1 (en) 2015-12-10
US20130184266A1 (en) 2013-07-18
CN103180326A (zh) 2013-06-26
CR20130066A (es) 2013-05-03
US20130190291A1 (en) 2013-07-25
MX349470B (es) 2017-07-31
US20120077799A1 (en) 2012-03-29
JP5788496B2 (ja) 2015-09-30
UY33551A (es) 2012-03-30
CL2013000380A1 (es) 2013-05-31
US20240360156A1 (en) 2024-10-31
US20190263832A1 (en) 2019-08-29
CY1123507T1 (el) 2022-03-24
US10654874B2 (en) 2020-05-19
DOP2013000030A (es) 2013-03-15
PH12013500247A1 (en) 2013-03-11
SG187656A1 (en) 2013-03-28
TWI504604B (zh) 2015-10-21
HRP20200844T1 (hr) 2020-08-21
MX2013001614A (es) 2013-07-05
EP2603513B1 (en) 2020-03-11
ZA201301120B (en) 2014-04-30
GEP20156216B (en) 2015-01-12

Similar Documents

Publication Publication Date Title
HUE049460T2 (hu) Heterociklusos vegyület és annak alkalmazása ampa receptor pozitív allosztérikus modulátorként
IL246600B (en) Heterocyclic compounds and their use
EP2637669A4 (en) Heterocyclic compounds and their use
IL222288A0 (en) Heterocyclic compounds and their uses
IL225770A0 (en) Heterocyclic compounds
IL221442A0 (en) Heterocyclic compound
ZA201300950B (en) Heterocyclic compound
IL237581B (en) Derivatives of 6-oxo-pyrazinopyrrolopyrimidines
PT2594567T (pt) Compostos de alquinil benzeno heterocíclicos e composições médicas e seus usos
IL231145A0 (en) Heterocyclic compounds and their uses
PL2521450T3 (pl) Grzybobójcze związki heterocykliczne
IL230536A0 (en) Heterocyclic compounds and their uses
EP2678016A4 (en) HETEROCYCLIC COMPOUNDS AND USES THEREOF
IL231783A0 (en) History of ethinyl as allosteric modulators of 5mglur
ZA201306586B (en) Thynyl derivatives as positive allosteric modulators of the mglur5
IL223721A0 (en) Heterocyclic compounds, their preparation and their therapeutic application
ZA201300157B (en) Fused heterocyclic derivatives as s1p modulators
EP2782571A4 (en) HETEROCYCLIC COMPOUNDS AND USES THEREOF
PL2769720T3 (pl) Heterocykliczne allosteryczne modulatory gsk-3
GB2477949B (en) Powering of devices
GB201009514D0 (en) Novel heterocyclic compounds
GB201021416D0 (en) Novel heterocyclic compounds
AU331233S (en) Powder applicator