MX2013001614A - Compuestos heterociclico. - Google Patents
Compuestos heterociclico.Info
- Publication number
- MX2013001614A MX2013001614A MX2013001614A MX2013001614A MX2013001614A MX 2013001614 A MX2013001614 A MX 2013001614A MX 2013001614 A MX2013001614 A MX 2013001614A MX 2013001614 A MX2013001614 A MX 2013001614A MX 2013001614 A MX2013001614 A MX 2013001614A
- Authority
- MX
- Mexico
- Prior art keywords
- heterocyclic compound
- compound
- ampa
- adhd
- schizophrenia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Se proporciona un compuesto representado por la fórmula (I): en donde cada símbolo es como se define en la especificación, o una sal del mismo, el cual tiene una acción potenciadora del receptor de AM PA (ácido a-amino-3-hidroxi-5-metil-4-isoxazolpropionico). El compuesto de la presente invención es útil como un fármaco profiláctico o terapéutico para depresión, esquizofrenia, enfermedad de Alzheimer o trastorno por déficit de atención con hiperactividad (ADHD), y similares.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010179577 | 2010-08-10 | ||
| PCT/JP2011/068497 WO2012020848A1 (en) | 2010-08-10 | 2011-08-09 | Heterocyclic compound and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013001614A true MX2013001614A (es) | 2013-07-05 |
| MX349470B MX349470B (es) | 2017-07-31 |
Family
ID=44534564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013001614A MX349470B (es) | 2010-08-10 | 2011-08-09 | Compuesto heterocíclico y su uso. |
Country Status (38)
| Country | Link |
|---|---|
| US (10) | US9150591B2 (es) |
| EP (1) | EP2603513B1 (es) |
| JP (2) | JP5788496B2 (es) |
| KR (1) | KR101852215B1 (es) |
| CN (2) | CN103180326B (es) |
| AR (1) | AR082618A1 (es) |
| AU (1) | AU2011290126B2 (es) |
| BR (1) | BR112013002250B1 (es) |
| CA (1) | CA2807460C (es) |
| CL (1) | CL2013000380A1 (es) |
| CO (1) | CO6680700A2 (es) |
| CR (1) | CR20130066A (es) |
| CY (1) | CY1123507T1 (es) |
| DK (1) | DK2603513T3 (es) |
| DO (1) | DOP2013000030A (es) |
| EA (1) | EA022078B1 (es) |
| EC (1) | ECSP13012478A (es) |
| ES (1) | ES2793723T3 (es) |
| GE (1) | GEP20156216B (es) |
| HR (1) | HRP20200844T1 (es) |
| HU (1) | HUE049460T2 (es) |
| IL (1) | IL224452A (es) |
| LT (1) | LT2603513T (es) |
| MA (1) | MA34509B1 (es) |
| MX (1) | MX349470B (es) |
| MY (1) | MY165908A (es) |
| NZ (1) | NZ607593A (es) |
| PE (1) | PE20131116A1 (es) |
| PL (1) | PL2603513T3 (es) |
| PT (1) | PT2603513T (es) |
| RS (1) | RS60311B1 (es) |
| SG (1) | SG187656A1 (es) |
| SI (1) | SI2603513T1 (es) |
| TW (1) | TWI504604B (es) |
| UA (1) | UA111594C2 (es) |
| UY (1) | UY33551A (es) |
| WO (1) | WO2012020848A1 (es) |
| ZA (1) | ZA201301120B (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE049460T2 (hu) * | 2010-08-10 | 2020-09-28 | Takeda Pharmaceuticals Co | Heterociklusos vegyület és annak alkalmazása ampa receptor pozitív allosztérikus modulátorként |
| WO2012137982A2 (en) * | 2011-04-05 | 2012-10-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
| JP6134654B2 (ja) * | 2012-02-08 | 2017-05-24 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| EP3311842A1 (en) * | 2013-06-13 | 2018-04-25 | VeroScience LLC | Compositions and methods for treating metabolic disorders |
| CA2916653C (en) | 2013-06-27 | 2017-07-18 | Pfizer Inc. | Heteroaromatic compounds and their use as dopamine d1 ligands |
| MY181117A (en) | 2013-12-03 | 2020-12-18 | Fmc Corp | Pyrrolidinone herbicides |
| US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
| WO2016003997A1 (en) | 2014-07-02 | 2016-01-07 | E. I. Du Pont De Nemours And Company | Piperidinone herbicides |
| KR102542215B1 (ko) | 2014-12-08 | 2023-06-12 | 에프엠씨 코포레이션 | 3-옥소-3-(아릴아미노)프로파노에이트, 이의 제조방법 및 피롤리디논 제조에 있어서 이의 용도 |
| CN107466290B (zh) | 2015-04-10 | 2021-08-03 | Fmc公司 | 作为除草剂的取代的环酰胺 |
| AU2016254958B2 (en) | 2015-04-27 | 2020-04-23 | Fmc Corporation | Butyrolactones as herbicides |
| WO2016176457A1 (en) * | 2015-04-29 | 2016-11-03 | Janssen Pharmaceutica Nv | Imidazopyrazines and pyrazolopyrimidines and their use as ampa receptor modulators |
| AU2016255434C1 (en) * | 2015-04-29 | 2021-09-23 | Rapport Therapeutics, Inc. | Azabenzimidazoles and their use as AMPA receptor modulators |
| EP3294743B1 (en) | 2015-05-12 | 2019-08-21 | FMC Corporation | Aryl substituted bicyclic compounds as herbicides |
| JP6869192B2 (ja) | 2015-05-29 | 2021-05-12 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 除草剤としての置換環状アミド |
| WO2016196593A1 (en) | 2015-06-02 | 2016-12-08 | E I Du Pont De Nemours And Company | Substituted cyclic amides and their use as herbicides |
| JP6937290B2 (ja) | 2015-07-31 | 2021-09-22 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 除草剤として有用な環状ｎ−カルボキサミド化合物 |
| TW201713774A (zh) | 2015-08-06 | 2017-04-16 | Kohjin Life Sciences Co Ltd | 含有β-菸鹼醯胺單核苷酸的酵母萃取物及其製造方法 |
| JP6940477B2 (ja) * | 2015-08-06 | 2021-09-29 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ＧａｌＮＡｃ酸誘導体の調製法 |
| US20170181292A1 (en) * | 2015-12-16 | 2017-06-22 | Rohm And Haas Electronic Materials Llc | Method for forming organic coating on nickel surface |
| CN105669731B (zh) * | 2016-01-10 | 2017-06-30 | 沧州普瑞东方科技有限公司 | 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法 |
| JP7325328B2 (ja) | 2016-12-21 | 2023-08-14 | エフ エム シー コーポレーション | ニトロン除草剤 |
| CN107892697B (zh) | 2016-12-26 | 2020-11-03 | 郑州泰基鸿诺医药股份有限公司 | 一种[1,3]噻嗪-2-胺类化合物及应用，药物组合物 |
| KR102620213B1 (ko) | 2017-03-21 | 2024-01-03 | 에프엠씨 코포레이션 | 피롤리디논 및 이의 제조 방법 |
| WO2018175231A1 (en) | 2017-03-21 | 2018-09-27 | Fmc Corporation | Herbicidal mixture, composition and method |
| AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
| AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
| US11407748B2 (en) | 2017-10-06 | 2022-08-09 | Takeda Pharmaceutical Company Limited | Substituted pyrido[1,2-a]pyrimidines and pyrazino[1,2-a]pyrimidines for enhancing AMPA receptor function |
| US11447488B2 (en) | 2017-10-06 | 2022-09-20 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds |
| TW202207944A (zh) * | 2020-05-15 | 2022-03-01 | 日商武田藥品工業股份有限公司 | 抑鬱症之治療 |
| CN113943294A (zh) * | 2020-07-15 | 2022-01-18 | 成都海博为药业有限公司 | 一种作为btk抑制剂的化合物及其制备方法与用途 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0437742Y2 (es) | 1986-10-22 | 1992-09-04 | ||
| JPH0285851A (ja) * | 1988-09-22 | 1990-03-27 | Konica Corp | 新規な写真用カプラー |
| JPH037742A (ja) | 1989-06-05 | 1991-01-14 | Toyo Tire & Rubber Co Ltd | ラバーチエーン用ゴム組成物 |
| JP2874960B2 (ja) | 1990-06-03 | 1999-03-24 | コニカ株式会社 | 新規な染料を含有するハロゲン化銀写真感光材料 |
| JPH04119890A (ja) | 1990-09-11 | 1992-04-21 | Konica Corp | ピラゾロチアジアジン系色素 |
| JP3430375B2 (ja) | 1993-11-12 | 2003-07-28 | コニカ株式会社 | 感熱転写材料及び該材料に好適な色素 |
| DE19704923A1 (de) | 1997-02-10 | 1998-08-13 | Hoechst Schering Agrevo Gmbh | Klebstoffhaltige Schädlingsbekämpfungsmittel |
| EP1229786A1 (en) | 1999-11-04 | 2002-08-14 | Colorado State University | Method and device for attracting insects |
| FR2801587B1 (fr) | 1999-11-30 | 2002-01-11 | Adir | Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2458388A1 (en) | 2001-10-10 | 2003-04-17 | Neurosearch A/S | Novel benzothiazine derivatives, their preparation and use |
| FR2833955B1 (fr) * | 2001-12-21 | 2004-01-30 | Servier Lab | Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2854634B1 (fr) * | 2003-05-05 | 2005-07-08 | Servier Lab | Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2865474B1 (fr) | 2004-01-26 | 2008-06-13 | Servier Lab | Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2879201B1 (fr) * | 2004-12-10 | 2007-02-16 | Servier Lab | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2655376A1 (en) | 2006-06-23 | 2007-12-27 | Nufarm Australia Limited | Phenoxy alkanoate herbicidal composition and method of preparation and use |
| US8097652B2 (en) | 2006-12-11 | 2012-01-17 | Eli Lilly And Company | AMPA receptor potentiators |
| US20080167374A1 (en) | 2007-01-09 | 2008-07-10 | Loveland Products, Inc. | Pesticide composition and method of use |
| US8487099B2 (en) * | 2007-11-05 | 2013-07-16 | Merck Sharp & Dohme Corp. | Gamma secretase modulators |
| JP2011507910A (ja) * | 2007-12-21 | 2011-03-10 | ユニバーシティー オブ ロチェスター | 真核生物の寿命を変更するための方法 |
| JPWO2009119088A1 (ja) | 2008-03-25 | 2011-07-21 | 武田薬品工業株式会社 | 複素環化合物 |
| JP2009248543A (ja) | 2008-04-11 | 2009-10-29 | Fujifilm Corp | 光情報記録媒体および情報記録方法 |
| TW201012803A (en) | 2008-06-06 | 2010-04-01 | Organon Nv | Heterocyclic derivatives |
| EP2356115A1 (en) * | 2008-11-06 | 2011-08-17 | Schering Corporation | Gamma secretase modulators |
| TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
| JP2012051806A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
| FR2943342B1 (fr) | 2009-03-20 | 2011-03-04 | Servier Lab | Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO2010140339A1 (ja) | 2009-06-01 | 2010-12-09 | 武田薬品工業株式会社 | 複素環化合物 |
| JPWO2011007756A1 (ja) | 2009-07-13 | 2012-12-27 | 武田薬品工業株式会社 | 複素環化合物及びその用途 |
| WO2011036885A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| WO2011036889A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| HUE049460T2 (hu) * | 2010-08-10 | 2020-09-28 | Takeda Pharmaceuticals Co | Heterociklusos vegyület és annak alkalmazása ampa receptor pozitív allosztérikus modulátorként |
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2011
- 2011-08-09 HU HUE11749944A patent/HUE049460T2/hu unknown
- 2011-08-09 CA CA2807460A patent/CA2807460C/en active Active
- 2011-08-09 DK DK11749944.2T patent/DK2603513T3/da active
- 2011-08-09 US US13/816,137 patent/US9150591B2/en active Active
- 2011-08-09 MA MA35708A patent/MA34509B1/fr unknown
- 2011-08-09 CN CN201180048970.3A patent/CN103180326B/zh active Active
- 2011-08-09 TW TW100128311A patent/TWI504604B/zh active
- 2011-08-09 MY MYPI2013000428A patent/MY165908A/en unknown
- 2011-08-09 WO PCT/JP2011/068497 patent/WO2012020848A1/en active Application Filing
- 2011-08-09 EP EP11749944.2A patent/EP2603513B1/en active Active
- 2011-08-09 NZ NZ607593A patent/NZ607593A/en unknown
- 2011-08-09 PT PT117499442T patent/PT2603513T/pt unknown
- 2011-08-09 PL PL11749944T patent/PL2603513T3/pl unknown
- 2011-08-09 PE PE2013000244A patent/PE20131116A1/es active IP Right Grant
- 2011-08-09 KR KR1020137006113A patent/KR101852215B1/ko active IP Right Grant
- 2011-08-09 SI SI201131887T patent/SI2603513T1/sl unknown
- 2011-08-09 UY UY0001033551A patent/UY33551A/es not_active Application Discontinuation
- 2011-08-09 GE GEAP201113021A patent/GEP20156216B/en unknown
- 2011-08-09 MX MX2013001614A patent/MX349470B/es active IP Right Grant
- 2011-08-09 US US13/206,113 patent/US8575154B2/en active Active
- 2011-08-09 ES ES11749944T patent/ES2793723T3/es active Active
- 2011-08-09 AU AU2011290126A patent/AU2011290126B2/en active Active
- 2011-08-09 SG SG2013007463A patent/SG187656A1/en unknown
- 2011-08-09 BR BR112013002250-7A patent/BR112013002250B1/pt active IP Right Grant
- 2011-08-09 LT LTEP11749944.2T patent/LT2603513T/lt unknown
- 2011-08-09 AR ARP110102905A patent/AR082618A1/es active IP Right Grant
- 2011-08-09 RS RS20200574A patent/RS60311B1/sr unknown
- 2011-08-09 EA EA201390222A patent/EA022078B1/ru not_active IP Right Cessation
- 2011-08-09 CN CN201510259936.0A patent/CN104926837A/zh active Pending
- 2011-08-09 JP JP2013506362A patent/JP5788496B2/ja active Active
- 2011-09-08 UA UAA201302884A patent/UA111594C2/uk unknown
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2013
- 2013-01-28 IL IL224452A patent/IL224452A/en active IP Right Grant
- 2013-02-05 DO DO2013000030A patent/DOP2013000030A/es unknown
- 2013-02-07 CL CL2013000380A patent/CL2013000380A1/es unknown
- 2013-02-12 ZA ZA2013/01120A patent/ZA201301120B/en unknown
- 2013-02-18 CR CR20130066A patent/CR20130066A/es unknown
- 2013-02-22 US US13/774,635 patent/US8778934B2/en active Active
- 2013-02-22 US US13/774,707 patent/US8916551B2/en active Active
- 2013-03-06 EC ECSP13012478 patent/ECSP13012478A/es unknown
- 2013-03-07 CO CO13046020A patent/CO6680700A2/es active IP Right Grant
-
2014
- 2014-11-13 US US14/540,699 patent/US20150073137A1/en not_active Abandoned
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2015
- 2015-07-21 US US14/804,935 patent/US9499568B2/en active Active
- 2015-07-29 JP JP2015149216A patent/JP6113789B2/ja active Active
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2016
- 2016-10-10 US US15/289,650 patent/US9884875B2/en active Active
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2017
- 2017-12-18 US US15/845,621 patent/US20180162875A1/en not_active Abandoned
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2019
- 2019-01-24 US US16/256,773 patent/US10654874B2/en active Active
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2020
- 2020-03-23 US US16/827,316 patent/US11279713B2/en active Active
- 2020-05-25 CY CY20201100475T patent/CY1123507T1/el unknown
- 2020-05-25 HR HRP20200844TT patent/HRP20200844T1/hr unknown
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