MX349470B - Compuesto heterocíclico y su uso. - Google Patents

Compuesto heterocíclico y su uso.

Info

Publication number
MX349470B
MX349470B MX2013001614A MX2013001614A MX349470B MX 349470 B MX349470 B MX 349470B MX 2013001614 A MX2013001614 A MX 2013001614A MX 2013001614 A MX2013001614 A MX 2013001614A MX 349470 B MX349470 B MX 349470B
Authority
MX
Mexico
Prior art keywords
heterocyclic compound
compound
ampa
adhd
schizophrenia
Prior art date
Application number
MX2013001614A
Other languages
English (en)
Spanish (es)
Other versions
MX2013001614A (es
Inventor
Kori Masakuni
Mochizuki Michiyo
Honda Eiji
Imaeda Toshihiro
Nakamura Shinji
Toyofuku Masashi
Asano Yasutomi
Ujitawa Osamu
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of MX2013001614A publication Critical patent/MX2013001614A/es
Publication of MX349470B publication Critical patent/MX349470B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
MX2013001614A 2010-08-10 2011-08-09 Compuesto heterocíclico y su uso. MX349470B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010179577 2010-08-10
PCT/JP2011/068497 WO2012020848A1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

Publications (2)

Publication Number Publication Date
MX2013001614A MX2013001614A (es) 2013-07-05
MX349470B true MX349470B (es) 2017-07-31

Family

ID=44534564

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013001614A MX349470B (es) 2010-08-10 2011-08-09 Compuesto heterocíclico y su uso.

Country Status (39)

Country Link
US (11) US8575154B2 (enExample)
EP (1) EP2603513B1 (enExample)
JP (2) JP5788496B2 (enExample)
KR (1) KR101852215B1 (enExample)
CN (2) CN103180326B (enExample)
AR (1) AR082618A1 (enExample)
AU (1) AU2011290126B2 (enExample)
BR (1) BR112013002250B1 (enExample)
CA (1) CA2807460C (enExample)
CL (1) CL2013000380A1 (enExample)
CO (1) CO6680700A2 (enExample)
CR (1) CR20130066A (enExample)
CY (1) CY1123507T1 (enExample)
DK (1) DK2603513T3 (enExample)
DO (1) DOP2013000030A (enExample)
EA (1) EA022078B1 (enExample)
EC (1) ECSP13012478A (enExample)
ES (1) ES2793723T3 (enExample)
GE (1) GEP20156216B (enExample)
HR (1) HRP20200844T1 (enExample)
HU (1) HUE049460T2 (enExample)
IL (1) IL224452A (enExample)
LT (1) LT2603513T (enExample)
MA (1) MA34509B1 (enExample)
MX (1) MX349470B (enExample)
MY (1) MY165908A (enExample)
NZ (1) NZ607593A (enExample)
PE (1) PE20131116A1 (enExample)
PH (1) PH12013500247A1 (enExample)
PL (1) PL2603513T3 (enExample)
PT (1) PT2603513T (enExample)
RS (1) RS60311B1 (enExample)
SG (1) SG187656A1 (enExample)
SI (1) SI2603513T1 (enExample)
TW (1) TWI504604B (enExample)
UA (1) UA111594C2 (enExample)
UY (1) UY33551A (enExample)
WO (1) WO2012020848A1 (enExample)
ZA (1) ZA201301120B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2603513T1 (sl) * 2010-08-10 2020-07-31 Takeda Pharmaceutical Company Limited Heterociklična spojina in njena uporaba kot pozitivni alosterični modulator receptorja AMPA
WO2012137982A2 (en) * 2011-04-05 2012-10-11 Takeda Pharmaceutical Company Limited Sulfonamide derivative and use thereof
US9493484B2 (en) 2012-02-08 2016-11-15 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
BR112015031249A2 (pt) * 2013-06-13 2017-07-25 Veroscience Llc método de tratamento, método para tratar um distúrbio metabólico ou um elemento chave do mesmo, método para normalizar um ritmo diário de liberação de dopamina no sumn, método para estimular a liberação de dopamina de neurônios dopaminérgicos no sumn de um indivíduo e composição farmacêutica
CN105324376B (zh) 2013-06-27 2017-06-23 辉瑞大药厂 杂芳族化合物及其作为多巴胺d1配体的用途
US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
MD4889C1 (ro) 2013-12-03 2024-10-31 Фмк Корпорейшн Pirolidinone în calitate de erbicide
WO2016003997A1 (en) 2014-07-02 2016-01-07 E. I. Du Pont De Nemours And Company Piperidinone herbicides
JP6611816B2 (ja) 2014-12-08 2019-11-27 エフ エム シー コーポレーション 3−オキソ−3−(アリールアミノ)プロパノエイト、その製造方法、およびピロリジノンの製造におけるその使用
US10405547B2 (en) 2015-04-10 2019-09-10 Fmc Corporation Substituted cyclic amides as herbicides
EP3288928B1 (en) 2015-04-27 2021-10-13 FMC Corporation Butyrolactones as herbicides
AU2016255431B2 (en) * 2015-04-29 2020-05-07 Janssen Pharmaceutica Nv Imidazopyrazines and pyrazolopyrimidines and their use as AMPA receptor modulators
HRP20210403T1 (hr) 2015-04-29 2021-10-29 Janssen Pharmaceutica Nv Azabenzimidazoli i njihova uporaba kao modulatora ampa receptora
CA2980643C (en) 2015-05-12 2023-10-17 E I Du Pont De Nemours And Company Aryl substituted bicyclic compounds as herbicides
CA2983590C (en) 2015-05-29 2021-11-30 E I Du Pont De Nemours And Company Substituted cyclic amides as herbicides
JP6949730B2 (ja) 2015-06-02 2021-10-13 エフ エム シー コーポレーションFmc Corporation 置換環状アミドおよび除草剤としてのそれらの使用
AU2016303209B2 (en) 2015-07-31 2021-04-01 Fmc Corporation Cyclic N-carboxamide compounds useful as herbicides
PL3331892T3 (pl) * 2015-08-06 2019-11-29 Hoffmann La Roche Sposób wytwarzania pochodnych kwasu GalNAc
US20170181292A1 (en) * 2015-12-16 2017-06-22 Rohm And Haas Electronic Materials Llc Method for forming organic coating on nickel surface
CN105669731B (zh) * 2016-01-10 2017-06-30 沧州普瑞东方科技有限公司 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法
BR112019012910B1 (pt) 2016-12-21 2023-10-17 Fmc Corporation Composto, composição herbicida, mistura herbicida e método para controlar o crescimento de vegetação indesejável
CN107892697B (zh) 2016-12-26 2020-11-03 郑州泰基鸿诺医药股份有限公司 一种[1,3]噻嗪-2-胺类化合物及应用,药物组合物
SG11201908640TA (en) 2017-03-21 2019-10-30 Fmc Corp Pyrrolidinones and a process to prepare them
BR112019019551A2 (pt) 2017-03-21 2020-04-22 Fmc Corp mistura, e, método para controlar o crescimento de vegetação indesejada
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
JP7250686B2 (ja) * 2017-10-06 2023-04-03 武田薬品工業株式会社 複素環化合物
EP3693360B1 (en) * 2017-10-06 2023-12-13 Takeda Pharmaceutical Company Limited Heterocyclic compounds
PL4031552T3 (pl) 2019-09-16 2025-03-17 Takeda Pharmaceutical Company Limited Pochodne azolowo-skondensowanych pirydazyn-3(2h)-onów
TW202207944A (zh) * 2020-05-15 2022-03-01 日商武田藥品工業股份有限公司 抑鬱症之治療
CN113943294A (zh) * 2020-07-15 2022-01-18 成都海博为药业有限公司 一种作为btk抑制剂的化合物及其制备方法与用途
WO2025226591A1 (en) 2024-04-22 2025-10-30 Neurocrine Biosciences, Inc. Methods of administering 9-[4-(cyclohexyloxy)phenyl]-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide without side effects
WO2026050231A1 (en) 2024-08-27 2026-03-05 Neurocrine Biosciences, Inc. Method of treating a bipolar disorder

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0437742Y2 (enExample) 1986-10-22 1992-09-04
JPH0285851A (ja) * 1988-09-22 1990-03-27 Konica Corp 新規な写真用カプラー
JPH037742A (ja) 1989-06-05 1991-01-14 Toyo Tire & Rubber Co Ltd ラバーチエーン用ゴム組成物
JP2874960B2 (ja) * 1990-06-03 1999-03-24 コニカ株式会社 新規な染料を含有するハロゲン化銀写真感光材料
JPH04119890A (ja) * 1990-09-11 1992-04-21 Konica Corp ピラゾロチアジアジン系色素
JP3430375B2 (ja) * 1993-11-12 2003-07-28 コニカ株式会社 感熱転写材料及び該材料に好適な色素
DE19704923A1 (de) 1997-02-10 1998-08-13 Hoechst Schering Agrevo Gmbh Klebstoffhaltige Schädlingsbekämpfungsmittel
JP2003526341A (ja) 1999-11-04 2003-09-09 コロラド ステート ユニバーシティー リサーチ ファウンデーション 昆虫を誘引するための装置および方法
FR2801587B1 (fr) 1999-11-30 2002-01-11 Adir Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1436270A1 (en) 2001-10-10 2004-07-14 Neurosearch A/S Novel benzothiazine derivatives, their preparation and use
FR2833955B1 (fr) * 2001-12-21 2004-01-30 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2854634B1 (fr) 2003-05-05 2005-07-08 Servier Lab Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2865474B1 (fr) 2004-01-26 2008-06-13 Servier Lab Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2040551A4 (en) 2006-06-23 2010-02-17 Nufarm Australia Ltd HERBIC PHENOXYALKANOATE COMPOSITION AND METHOD FOR THE PRODUCTION AND USE THEREOF
US8097652B2 (en) 2006-12-11 2012-01-17 Eli Lilly And Company AMPA receptor potentiators
US20080167374A1 (en) 2007-01-09 2008-07-10 Loveland Products, Inc. Pesticide composition and method of use
EP2217604A1 (en) * 2007-11-05 2010-08-18 Schering Corporation Gamma secretase modulators
US8642660B2 (en) * 2007-12-21 2014-02-04 The University Of Rochester Method for altering the lifespan of eukaryotic organisms
EP2269990A4 (en) 2008-03-25 2012-04-18 Takeda Pharmaceutical Heterocyclic compound
JP2009248543A (ja) * 2008-04-11 2009-10-29 Fujifilm Corp 光情報記録媒体および情報記録方法
TW201012803A (en) * 2008-06-06 2010-04-01 Organon Nv Heterocyclic derivatives
CA2742317A1 (en) * 2008-11-06 2010-05-14 Schering Corporation Gamma secretase modulators
TW201030002A (en) 2009-01-16 2010-08-16 Bristol Myers Squibb Co Bicyclic compounds for the reduction of beta-amyloid production
JP2012051806A (ja) 2009-02-26 2012-03-15 Eisai R & D Management Co Ltd イミダゾリルピラジン誘導体
FR2943342B1 (fr) 2009-03-20 2011-03-04 Servier Lab Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
WO2010140339A1 (ja) 2009-06-01 2010-12-09 武田薬品工業株式会社 複素環化合物
US20120142672A1 (en) 2009-07-13 2012-06-07 Tatsuki Koike Heterocyclic compound and use thereof
WO2011036885A1 (ja) 2009-09-25 2011-03-31 武田薬品工業株式会社 複素環化合物
WO2011036889A1 (ja) 2009-09-25 2011-03-31 武田薬品工業株式会社 複素環化合物
SI2603513T1 (sl) * 2010-08-10 2020-07-31 Takeda Pharmaceutical Company Limited Heterociklična spojina in njena uporaba kot pozitivni alosterični modulator receptorja AMPA

Also Published As

Publication number Publication date
US20140080817A1 (en) 2014-03-20
CA2807460A1 (en) 2012-02-16
JP6113789B2 (ja) 2017-04-12
ZA201301120B (en) 2014-04-30
CN103180326A (zh) 2013-06-26
US9499568B2 (en) 2016-11-22
US20130190291A1 (en) 2013-07-25
UY33551A (es) 2012-03-30
AU2011290126A1 (en) 2013-03-07
BR112013002250B1 (pt) 2020-10-27
HUE049460T2 (hu) 2020-09-28
US8778934B2 (en) 2014-07-15
LT2603513T (lt) 2020-05-25
EP2603513B1 (en) 2020-03-11
KR20130138738A (ko) 2013-12-19
US9150591B2 (en) 2015-10-06
WO2012020848A8 (en) 2012-09-27
ECSP13012478A (es) 2013-04-30
CL2013000380A1 (es) 2013-05-31
US8916551B2 (en) 2014-12-23
PE20131116A1 (es) 2013-10-24
PL2603513T3 (pl) 2020-07-27
DK2603513T3 (da) 2020-06-15
MY165908A (en) 2018-05-18
AR082618A1 (es) 2012-12-19
IL224452A (en) 2017-11-30
TWI504604B (zh) 2015-10-21
US20200317692A1 (en) 2020-10-08
HRP20200844T1 (hr) 2020-08-21
CA2807460C (en) 2018-09-18
JP2016006080A (ja) 2016-01-14
US20170022222A1 (en) 2017-01-26
SI2603513T1 (sl) 2020-07-31
UA111594C2 (uk) 2016-05-25
CO6680700A2 (es) 2013-05-31
US20190263832A1 (en) 2019-08-29
PT2603513T (pt) 2020-06-08
US20240360156A1 (en) 2024-10-31
CN103180326B (zh) 2015-06-10
TW201217386A (en) 2012-05-01
NZ607593A (en) 2015-01-30
US20150353578A1 (en) 2015-12-10
US11279713B2 (en) 2022-03-22
US10654874B2 (en) 2020-05-19
EA022078B1 (ru) 2015-10-30
CN104926837A (zh) 2015-09-23
PH12013500247A1 (en) 2013-03-11
MA34509B1 (fr) 2013-09-02
US20130184266A1 (en) 2013-07-18
ES2793723T3 (es) 2020-11-16
US20180162875A1 (en) 2018-06-14
RS60311B1 (sr) 2020-07-31
SG187656A1 (en) 2013-03-28
BR112013002250A2 (pt) 2016-05-24
DOP2013000030A (es) 2013-03-15
CY1123507T1 (el) 2022-03-24
EP2603513A1 (en) 2013-06-19
JP5788496B2 (ja) 2015-09-30
GEP20156216B (en) 2015-01-12
US9884875B2 (en) 2018-02-06
EA201390222A1 (ru) 2013-08-30
WO2012020848A1 (en) 2012-02-16
CR20130066A (es) 2013-05-03
KR101852215B1 (ko) 2018-04-25
JP2013535408A (ja) 2013-09-12
US20120077799A1 (en) 2012-03-29
AU2011290126B2 (en) 2016-01-07
US8575154B2 (en) 2013-11-05
MX2013001614A (es) 2013-07-05
US20150073137A1 (en) 2015-03-12

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