AU2011239525B2 - Pyrrolobenzodiazepines used to treat proliferative diseases - Google Patents

Pyrrolobenzodiazepines used to treat proliferative diseases Download PDF

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Publication number
AU2011239525B2
AU2011239525B2 AU2011239525A AU2011239525A AU2011239525B2 AU 2011239525 B2 AU2011239525 B2 AU 2011239525B2 AU 2011239525 A AU2011239525 A AU 2011239525A AU 2011239525 A AU2011239525 A AU 2011239525A AU 2011239525 B2 AU2011239525 B2 AU 2011239525B2
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AU2011239525A1 (en
Inventor
Patrick Burke
Philip Wilson Howard
Scott Jeffrey
Luke Masterson
Peter Senter
Arnaud Tiberghien
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MedImmune Ltd
Seagen Inc
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MedImmune Ltd
Seagen Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
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    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

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  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Dermatology (AREA)
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  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
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  • Pain & Pain Management (AREA)
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  • Gynecology & Obstetrics (AREA)
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AU2011239525A 2010-04-15 2011-04-15 Pyrrolobenzodiazepines used to treat proliferative diseases Active AU2011239525B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32445310P 2010-04-15 2010-04-15
US61/324,453 2010-04-15
PCT/US2011/032668 WO2011130616A1 (en) 2010-04-15 2011-04-15 Pyrrolobenzodiazepines used to treat proliferative diseases

Publications (2)

Publication Number Publication Date
AU2011239525A1 AU2011239525A1 (en) 2012-11-01
AU2011239525B2 true AU2011239525B2 (en) 2015-04-09

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EP (2) EP2789622B1 (US07794700-20100914-C00152.png)
JP (1) JP5875083B2 (US07794700-20100914-C00152.png)
KR (1) KR101687054B1 (US07794700-20100914-C00152.png)
CN (1) CN102971329B (US07794700-20100914-C00152.png)
AU (1) AU2011239525B2 (US07794700-20100914-C00152.png)
BR (1) BR112012026410B8 (US07794700-20100914-C00152.png)
CA (1) CA2795353C (US07794700-20100914-C00152.png)
ES (1) ES2623057T3 (US07794700-20100914-C00152.png)
HK (1) HK1202536A1 (US07794700-20100914-C00152.png)
MX (2) MX339185B (US07794700-20100914-C00152.png)
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WO (1) WO2011130616A1 (US07794700-20100914-C00152.png)
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WO2011130616A1 (en) 2010-04-15 2011-10-20 Spirogen Limited Pyrrolobenzodiazepines used to treat proliferative diseases
KR101671360B1 (ko) 2010-04-15 2016-11-01 시애틀 지네틱스, 인크. 표적화된 피롤로벤조디아제핀 접합체
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EP3388435B1 (en) 2011-10-14 2023-05-03 Seagen Inc. Pyrrolobenzodiazepines and targeted conjugates
BR112014008981A2 (pt) 2011-10-14 2017-05-02 Spirogen Sàrl pirrolobenzodiazepinas
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