ATA195588A - Epipodophyllotoxinglucosid-4'-phosphat-derivate deren herstellung, sowie pharmazeutische zusammensetzungen hierzu - Google Patents

Epipodophyllotoxinglucosid-4'-phosphat-derivate deren herstellung, sowie pharmazeutische zusammensetzungen hierzu

Info

Publication number
ATA195588A
ATA195588A AT0195588A AT195588A ATA195588A AT A195588 A ATA195588 A AT A195588A AT 0195588 A AT0195588 A AT 0195588A AT 195588 A AT195588 A AT 195588A AT A195588 A ATA195588 A AT A195588A
Authority
AT
Austria
Prior art keywords
epipodophyllotoxinglucoside
production
pharmaceutical compositions
phosphate derivatives
phosphate
Prior art date
Application number
AT0195588A
Other languages
English (en)
Other versions
AT398974B (de
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ATA195588A publication Critical patent/ATA195588A/de
Application granted granted Critical
Publication of AT398974B publication Critical patent/AT398974B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Cable Accessories (AREA)
AT0195588A 1987-08-04 1988-08-03 Epipodophyllotoxinglucosid-4'-phosphat-derivate deren herstellung, sowie pharmazeutische zusammensetzungen hierzu AT398974B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8149387A 1987-08-04 1987-08-04
US07/199,731 US4904768A (en) 1987-08-04 1988-05-27 Epipodophyllotoxin glucoside 4'-phosphate derivatives

Publications (2)

Publication Number Publication Date
ATA195588A true ATA195588A (de) 1994-07-15
AT398974B AT398974B (de) 1995-02-27

Family

ID=26765636

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0195588A AT398974B (de) 1987-08-04 1988-08-03 Epipodophyllotoxinglucosid-4'-phosphat-derivate deren herstellung, sowie pharmazeutische zusammensetzungen hierzu

Country Status (34)

Country Link
US (3) US4904768A (de)
JP (1) JPH0699465B2 (de)
KR (1) KR900006230B1 (de)
CN (1) CN1027169C (de)
AT (1) AT398974B (de)
BE (1) BE1002982A4 (de)
CA (1) CA1310637C (de)
CH (1) CH676716A5 (de)
CY (1) CY1625A (de)
CZ (1) CZ286893B6 (de)
DD (2) DD274423A5 (de)
DE (1) DE3826562A1 (de)
DK (2) DK169344B1 (de)
ES (1) ES2010775A6 (de)
FI (1) FI87790C (de)
FR (1) FR2622193B1 (de)
GB (1) GB2207674B (de)
GR (1) GR1000490B (de)
HK (1) HK6392A (de)
HU (3) HU202547B (de)
IE (1) IE61040B1 (de)
IL (1) IL87290A (de)
IT (1) IT1226825B (de)
LU (2) LU87290A1 (de)
MX (1) MX173843B (de)
MY (1) MY104321A (de)
NL (2) NL192683C (de)
NO (4) NO170284C (de)
NZ (1) NZ225615A (de)
PT (1) PT88186B (de)
SE (1) SE502214C2 (de)
SG (1) SG101291G (de)
SK (1) SK279325B6 (de)
YU (3) YU143688A (de)

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US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives
US6610299B1 (en) 1989-10-19 2003-08-26 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US7241595B2 (en) 1989-10-20 2007-07-10 Sanofi-Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US6475486B1 (en) 1990-10-18 2002-11-05 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US5552154A (en) * 1989-11-06 1996-09-03 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof
US5034380A (en) * 1989-11-20 1991-07-23 Bristol-Myers Squibb Company Alkoxymethylidene epipodophyllotoxin glucosides
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US6080751A (en) * 1992-01-14 2000-06-27 The Stehlin Foundation For Cancer Research Method for treating pancreatic cancer in humans with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof
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US6624317B1 (en) 2000-09-25 2003-09-23 The University Of North Carolina At Chapel Hill Taxoid conjugates as antimitotic and antitumor agents
US6506739B1 (en) 2001-05-01 2003-01-14 Telik, Inc. Bis-(N,N'-bis-(2-haloethyl)amino)phosphoramidates as antitumor agents
WO2003035661A1 (en) * 2001-10-26 2003-05-01 Centre National De La Recherche Scientifique Derivatives of etoposide and analogs, and pharmaceutical compositions containing them
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FR2397425A1 (fr) * 1977-07-11 1979-02-09 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
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Also Published As

Publication number Publication date
NZ225615A (en) 1991-06-25
IT1226825B (it) 1991-02-19
LU87290A1 (fr) 1990-02-07
IL87290A (en) 1993-01-31
CZ286893B6 (cs) 2000-07-12
MY104321A (en) 1994-03-31
NL192683C (nl) 1997-12-02
HK6392A (en) 1992-01-17
NL8801934A (nl) 1989-03-01
NL970042I2 (de) 2005-06-01
CH676716A5 (de) 1991-02-28
FI87790C (fi) 1993-02-25
FI883596A0 (fi) 1988-08-01
IE882378L (en) 1989-02-04
FR2622193A1 (fr) 1989-04-28
DK169344B1 (da) 1994-10-10
JPH01100188A (ja) 1989-04-18
SE502214C2 (sv) 1995-09-18
DK11992A (da) 1992-01-31
US5041424A (en) 1991-08-20
BE1002982A4 (fr) 1991-10-15
YU10390A (en) 1990-06-30
FI87790B (fi) 1992-11-13
AT398974B (de) 1995-02-27
DD274423A5 (de) 1989-12-20
NO170284C (no) 1992-09-30
NL192683B (de) 1997-08-01
PT88186B (pt) 1995-07-03
IL87290A0 (en) 1989-01-31
GR880100512A (en) 1989-05-25
FR2622193B1 (fr) 1993-12-17
HU208147B (en) 1993-08-30
DK434088A (da) 1989-02-05
CZ541288A3 (cs) 1999-12-15
NO883299L (no) 1989-02-24
CA1310637C (en) 1992-11-24
GB8818462D0 (en) 1988-09-07
GR1000490B (el) 1992-07-30
US4904768A (en) 1990-02-27
GB2207674B (en) 1991-09-11
SE8802815D0 (sv) 1988-08-03
PT88186A (pt) 1989-06-30
SK541288A3 (en) 1998-10-07
NO883299D0 (no) 1988-07-26
HU211960A9 (en) 1996-01-29
DK434088D0 (da) 1988-08-03
YU10490A (en) 1990-06-30
NO920277D0 (no) 1992-01-22
DD299067A5 (de) 1992-03-26
YU143688A (en) 1990-04-30
KR890003790A (ko) 1989-04-18
CN1061225A (zh) 1992-05-20
ES2010775A6 (es) 1989-12-01
HU905862D0 (en) 1991-03-28
CY1625A (en) 1992-07-10
FI883596A (fi) 1989-02-05
NO1998002I1 (no) 1998-01-14
KR900006230B1 (ko) 1990-08-27
DE3826562C2 (de) 1993-04-08
NO920665D0 (no) 1992-02-20
SE8802815L (sv) 1989-02-05
DE3826562A1 (de) 1989-02-16
NO170284B (no) 1992-06-22
HU202547B (en) 1991-03-28
AU2030688A (en) 1989-06-08
MX173843B (es) 1994-03-30
NO172440B (no) 1993-04-13
NL970042I1 (nl) 1998-03-02
CN1027169C (zh) 1994-12-28
USRE35524E (en) 1997-06-03
IE61040B1 (en) 1994-09-07
SG101291G (en) 1992-01-17
MX9202851A (es) 1992-06-30
HUT47303A (en) 1989-02-28
DK11992D0 (da) 1992-01-31
NO172440C (no) 1993-07-21
NO920665L (no) 1989-02-24
GB2207674A (en) 1989-02-08
IT8821535A0 (it) 1988-07-28
LU90138I2 (fr) 1997-11-26
JPH0699465B2 (ja) 1994-12-07
SK279325B6 (sk) 1998-10-07
NO920277L (no) 1989-02-24
AU610619B2 (en) 1991-05-23

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