IT8547538A0 - 8 alfa-acilamminoergoline,loro preparazione e loro impiego come medicamenti - Google Patents

8 alfa-acilamminoergoline,loro preparazione e loro impiego come medicamenti

Info

Publication number
IT8547538A0
IT8547538A0 IT8547538A IT4753885A IT8547538A0 IT 8547538 A0 IT8547538 A0 IT 8547538A0 IT 8547538 A IT8547538 A IT 8547538A IT 4753885 A IT4753885 A IT 4753885A IT 8547538 A0 IT8547538 A0 IT 8547538A0
Authority
IT
Italy
Prior art keywords
acylaminoergolines
medicines
alpha
preparation
Prior art date
Application number
IT8547538A
Other languages
English (en)
Other versions
IT1214648B (it
Inventor
Haefliger Walter
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8547538A0 publication Critical patent/IT8547538A0/it
Application granted granted Critical
Publication of IT1214648B publication Critical patent/IT1214648B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
IT8547538A 1984-01-12 1985-01-11 8 alfa-acilamminoergoline,loro preparazione e loro impiego come medicamenti IT1214648B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3400853 1984-01-12

Publications (2)

Publication Number Publication Date
IT8547538A0 true IT8547538A0 (it) 1985-01-11
IT1214648B IT1214648B (it) 1990-01-18

Family

ID=6224786

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8547538A IT1214648B (it) 1984-01-12 1985-01-11 8 alfa-acilamminoergoline,loro preparazione e loro impiego come medicamenti

Country Status (28)

Country Link
US (2) US4950672A (it)
JP (1) JPH0655739B2 (it)
AT (1) AT391317B (it)
AU (3) AU583489B2 (it)
BE (1) BE901456A (it)
CA (1) CA1245640A (it)
CH (1) CH664568A5 (it)
CY (1) CY1542A (it)
DE (1) DE3500251C2 (it)
DK (1) DK169891B1 (it)
ES (1) ES8605514A1 (it)
FI (1) FI82466C (it)
FR (1) FR2560196B1 (it)
GB (1) GB2152507B (it)
GR (1) GR850065B (it)
HK (1) HK48590A (it)
HU (1) HU197569B (it)
IE (1) IE58228B1 (it)
IL (1) IL74043A (it)
IT (1) IT1214648B (it)
LU (1) LU85725A1 (it)
NL (1) NL193541C (it)
NZ (1) NZ210818A (it)
PH (1) PH23286A (it)
PT (1) PT79818B (it)
SE (1) SE460420B (it)
SG (1) SG32390G (it)
ZA (1) ZA85276B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
ATE107647T1 (de) * 1984-04-09 1994-07-15 Schering Ag 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
NL8700046A (nl) * 1986-01-24 1987-08-17 Sandoz Ag 8 alfa-acylaminoergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
US4931447A (en) * 1987-06-15 1990-06-05 Eli Lilly And Company Cycloalkylamides of (8β)-1-alkyl-6-(substituted) ergolines
US4981859A (en) * 1987-06-15 1991-01-01 Cycloalkylamides of (8 beta )-1-alkyl-6-(substituted)ergolines
IT1219652B (it) * 1987-06-23 1990-05-24 Sandoz Ag 8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto
DE3820159A1 (de) * 1987-06-23 1989-01-05 Sandoz Ag 8(alpha)-acylaminoergolin, seine herstellung und dieses enthaltende arzneimittel
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
GB8824744D0 (en) * 1988-10-21 1988-11-30 Erba Carlo Spa Antiemesis ergoline derivatives
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
EP3253753A4 (en) 2015-01-20 2018-06-27 Xoc Pharmaceuticals, Inc Ergoline compounds and uses thereof
JP2018502889A (ja) 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ イソエルゴリン化合物およびその使用
BR112019025420A2 (pt) 2017-06-01 2020-06-16 Xoc Pharmaceuticals, Inc. Compostos policíclicos e usos destes

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218323A (en) * 1965-11-16 Esters of i,g-dimethyl-b-ergolenyl carbamic acid
US2864822A (en) * 1956-10-22 1958-12-16 Lilly Co Eli 9-amino-7-methyl-belta10-ergolene and derivatives thereof
CH622519A5 (en) * 1974-07-05 1981-04-15 Hoechst Ag Process for the preparation of hydroxyalkylxanthines
GB1517972A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-cyanomethylergoline i
US4348392A (en) * 1974-07-19 1982-09-07 Sandoz Ltd. 8α-Substituted ergoline-I derivatives
US3922347A (en) * 1974-12-19 1975-11-25 Lilly Co Eli Method of inhibiting prolactin secretion with 8-acylaminoergolenes
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
CH622518A5 (en) * 1976-12-14 1981-04-15 Sandoz Ag Process for the preparation of novel ergoline compounds
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.
IT1219652B (it) * 1987-06-23 1990-05-24 Sandoz Ag 8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto

Also Published As

Publication number Publication date
AU609539B2 (en) 1991-05-02
ATA5985A (de) 1990-03-15
IT1214648B (it) 1990-01-18
AT391317B (de) 1990-09-25
NZ210818A (en) 1989-02-24
IE58228B1 (en) 1993-08-11
AU3760985A (en) 1985-07-18
AU583489B2 (en) 1989-05-04
US4950672A (en) 1990-08-21
FI82466B (fi) 1990-11-30
DE3500251C2 (de) 1995-01-26
CA1245640A (en) 1988-11-29
IE850064L (en) 1985-07-12
PT79818A (en) 1985-02-01
NL193541C (nl) 2000-01-04
HK48590A (en) 1990-06-29
AU2506688A (en) 1989-02-23
JPS60174783A (ja) 1985-09-09
FI850130L (fi) 1985-07-13
AU618290B2 (en) 1991-12-19
ES539511A0 (es) 1986-03-16
AU2506788A (en) 1989-03-02
NL8500008A (nl) 1985-08-01
CH664568A5 (de) 1988-03-15
HU197569B (en) 1989-04-28
SE460420B (sv) 1989-10-09
IL74043A0 (en) 1985-04-30
DK12685A (da) 1985-07-13
SE8500107D0 (sv) 1985-01-10
HUT37148A (en) 1985-11-28
GR850065B (it) 1985-05-03
PH23286A (en) 1989-06-30
FI850130A0 (fi) 1985-01-11
JPH0655739B2 (ja) 1994-07-27
CY1542A (en) 1991-03-22
IL74043A (en) 1988-10-31
SG32390G (en) 1990-08-03
DE3500251A1 (de) 1985-07-18
GB2152507A (en) 1985-08-07
PT79818B (en) 1987-01-07
FR2560196B1 (fr) 1986-07-18
ES8605514A1 (es) 1986-03-16
FR2560196A1 (fr) 1985-08-30
GB2152507B (en) 1987-07-15
NL193541B (nl) 1999-09-01
SE8500107L (sv) 1985-07-13
DK12685D0 (da) 1985-01-10
LU85725A1 (fr) 1985-10-22
US5077298A (en) 1991-12-31
GB8500454D0 (en) 1985-02-13
BE901456A (fr) 1985-07-08
ZA85276B (en) 1986-08-27
FI82466C (fi) 1991-03-11
DK169891B1 (da) 1995-03-27

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