TWI670371B - 用於細胞冷凍保存的組成物和方法 - Google Patents
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- TWI670371B TWI670371B TW106134217A TW106134217A TWI670371B TW I670371 B TWI670371 B TW I670371B TW 106134217 A TW106134217 A TW 106134217A TW 106134217 A TW106134217 A TW 106134217A TW I670371 B TWI670371 B TW I670371B
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- cells
- cryopreservation
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- cell
- freezing
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- A01N1/10—Preservation of living parts
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- A01N1/122—Preservation or perfusion media
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
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- C12N5/0068—General culture methods using substrates
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0656—Adult fibroblasts
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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| US20220125042A1 (en) * | 2017-05-17 | 2022-04-28 | Universidade Nova De Lisboa | Cryoprotectant and/or cryopreservant composition, methods and uses thereof |
| EP3680324A4 (en) * | 2017-09-08 | 2021-06-16 | Otsuka Pharmaceutical Factory, Inc. | Stem cells derived from young pig and preparation method therefor |
| JP7000212B2 (ja) * | 2018-03-14 | 2022-01-19 | 旭化成株式会社 | 幹細胞の凍結保存液 |
| CN108552158A (zh) * | 2018-04-09 | 2018-09-21 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 一种贴壁细胞冻存液、冻存方法和解冻方法 |
| CN108728408B (zh) * | 2018-05-28 | 2021-08-24 | 天津博雅秀岩生物技术有限公司 | 犬胎膜间充质干细胞及制备方法和使用的培养基 |
| US20200046771A1 (en) * | 2018-07-27 | 2020-02-13 | Cellphire, Inc. | Cryopreserved platelet compositions and methods for making |
| CA3121200A1 (en) | 2018-11-30 | 2020-06-04 | Cellphire, Inc. | Platelets as delivery agents |
| WO2020112963A1 (en) | 2018-11-30 | 2020-06-04 | Cellphire, Inc. | Platelets as delivery agents |
| JP7524077B2 (ja) * | 2019-01-17 | 2024-07-29 | 長瀬産業株式会社 | 細胞凍結保存液 |
| WO2020168340A1 (en) * | 2019-02-15 | 2020-08-20 | Doody Michael C | In vitro fertilization media with antiviral medicine |
| CN109792985A (zh) * | 2019-02-20 | 2019-05-24 | 华东理工大学 | 细胞冻存液 |
| EP3939427A4 (en) * | 2019-04-09 | 2022-07-13 | Peking University Third Hospital | CRYOPRESERVATION SOLUTION WITHOUT DMSO, PROCESS FOR ITS PREPARATION AND ITS USE |
| SG11202111764RA (en) * | 2019-04-26 | 2021-11-29 | Otsuka Pharma Factory Inc | Trehalose-containing liquid for mammalian cell preservation |
| WO2020223125A1 (en) * | 2019-04-30 | 2020-11-05 | Regents Of The University Of Minnesota | Composition and method for cryopreservation of cells |
| IL322149A (en) | 2019-05-03 | 2025-09-01 | Cellphire Inc | Materials and methods for manufacturing blood products |
| KR102487903B1 (ko) * | 2019-06-02 | 2023-01-12 | (주)카스 인 바이오 | 연질 생체 조직을 미립자화하는 방법 및 이의 방법으로 제조된 연질 생체 조직 미립자 이식편 |
| KR20220031555A (ko) | 2019-06-11 | 2022-03-11 | 옥소젠 코포레이션 | 조직의 습식 보존 |
| US20210100846A1 (en) * | 2019-07-17 | 2021-04-08 | Cellphire, Inc. | Use of platelets in treating infections |
| CN114450066A (zh) | 2019-08-16 | 2022-05-06 | 塞尔菲乐有限公司 | 作为抗血小板剂逆转剂的血栓小体 |
| WO2021092199A1 (en) * | 2019-11-08 | 2021-05-14 | Kansas State University Research Foundation | Isolation, preservation, and expansion of canine umbilical cord mesenchymal stromal cells |
| CN111066776A (zh) * | 2019-11-09 | 2020-04-28 | 无锡市人民医院 | 一种卵子冷冻保护剂及其应用 |
| EP4064837A4 (en) * | 2019-11-29 | 2023-01-04 | Rutgers, the State University of New Jersey | COMPOSITIONS, KITS AND METHODS FOR STORING BLOOD PRODUCTS AND METHODS OF USE THEREOF |
| EP4065690A4 (en) | 2019-11-29 | 2022-10-05 | Rutgers, the State University of New Jersey | METHODS OF ISOLATING UMBRELLA PLASMA PRODUCTS, TISSUE AND CELL EXOSOMES AND COMPOSITIONS AND METHODS OF USE THEREOF |
| CN110934132A (zh) * | 2019-12-30 | 2020-03-31 | 苏州君欣生物科技有限公司 | 一种无血清无dmso细胞冻存液及其制备方法 |
| KR102542183B1 (ko) * | 2019-12-31 | 2023-06-14 | (주)두다 | 치아 유래 줄기세포의 분리를 위한 치아의 보존 방법 |
| BR112022014246A2 (pt) * | 2020-01-21 | 2022-09-20 | Takeda Pharmaceuticals Co | Meio de criopreservação para criopreservar células de mamífero, kit, e, métodos de criopreservação de células de mamífero e recuperação de células viáveis |
| CA3170196A1 (en) | 2020-02-04 | 2021-08-12 | Cellphire, Inc. | Anti-fibrinolytic loaded platelets |
| WO2021231806A1 (en) * | 2020-05-13 | 2021-11-18 | Rapa Therapeutics, Llc | Antigen presenting t cells, sensitized, manufactured t cells and methods of treatment using the same |
| GB202007905D0 (en) * | 2020-05-27 | 2020-07-08 | Univ Edinburgh | Cryopressing macrophages |
| JP2023525357A (ja) * | 2020-06-26 | 2023-06-15 | メプスゲン カンパニー リミテッド | 臓器チップの凍結保存方法 |
| CN116234441B (zh) * | 2020-08-18 | 2026-02-27 | 伊奇洛夫科技有限公司 | 用于器官保存的装置和方法 |
| CN111979172A (zh) * | 2020-08-31 | 2020-11-24 | 安徽惠恩生物科技股份有限公司 | 一种让细胞保持较长时间活性的输注液及其制备方法 |
| CN114158549B (zh) * | 2020-09-10 | 2023-10-03 | 上海原天生物科技有限公司 | 一种免疫细胞的置核冻存方法 |
| US12453805B2 (en) | 2020-09-24 | 2025-10-28 | Everest Medical Innovation GmbH | Cryoprotective compositions, surgical kits, and methods for protection of a surgical site during cryosurgery |
| US12426594B2 (en) | 2020-09-24 | 2025-09-30 | Everest Medical Innovation GmbH | Cryoprotective compositions and methods for protection of a surgical site during cryosurgery |
| CN112167243B (zh) * | 2020-10-14 | 2023-03-10 | 中国科学技术大学 | 红细胞冻存液及快速冻存方法 |
| CN116472283A (zh) * | 2020-10-29 | 2023-07-21 | 国立大学法人大阪大学 | 细胞结构体的冷冻方法 |
| US20220211029A1 (en) * | 2020-11-10 | 2022-07-07 | Cellphire, Inc. | Freeze-dried peripheral blood mononuclear cell compositions and methods |
| JP7266892B2 (ja) * | 2020-11-16 | 2023-05-01 | 株式会社アビー | 細胞凍結保存液、凍結細胞保存方法、及び細胞凍結方法 |
| CN112438252B (zh) * | 2020-11-20 | 2021-06-08 | 上海欧易生物医学科技有限公司 | 一种适用于小鼠心脏组织单细胞测序的组织冷冻及解冻方法 |
| CN112616827B (zh) * | 2020-11-30 | 2022-05-13 | 中国科学技术大学 | 红细胞冻存方法及冻存的红细胞 |
| CN112649268A (zh) * | 2020-12-14 | 2021-04-13 | 四川农业大学 | 精子质膜保护剂hepes/bsa及染色液和染色方法 |
| CN112514892B (zh) * | 2020-12-25 | 2022-06-14 | 广州赛莱拉干细胞科技股份有限公司 | 一种外泌体冻存保护液及其制备方法 |
| CA3174826A1 (en) * | 2021-01-19 | 2022-07-28 | Katsuro HAGIWARA | Virus stabilizer, gelatin hydrolysate for virus stabilizer, and virus-containing composition |
| TW202245814A (zh) | 2021-02-17 | 2022-12-01 | 美商賽菲爾公司 | 用於治療抗血小板誘導的凝血病之凍乾血小板衍生物組成物 |
| CN117177663A (zh) * | 2021-04-05 | 2023-12-05 | 库瑞欧库瑞特有限公司 | 消除了对细胞渗透性防冻剂的需要的高效生物相容性冷冻保存培养基 |
| CN114073249B (zh) * | 2021-10-29 | 2024-01-02 | 上海原天生物科技有限公司 | 一种人t淋巴细胞的慢速冻存方法 |
| CN114375944A (zh) * | 2021-12-31 | 2022-04-22 | 四川大学华西医院 | 一种用于骨组织和骨软组织的冻存液和冻存方法 |
| CN114642200B (zh) * | 2022-03-01 | 2023-03-03 | 长春科技学院 | 一种鹿茸生茸区骨膜的冷冻保存方法 |
| WO2023180635A1 (fr) * | 2022-03-22 | 2023-09-28 | Sorbonne Universite | Methode de conservation de cellules |
| CN114711225B (zh) * | 2022-03-29 | 2023-08-29 | 中国科学技术大学 | 卵泡的冷冻保存和复苏方法 |
| CN114667999A (zh) * | 2022-05-27 | 2022-06-28 | 广东先康达生物科技有限公司 | 一种免疫细胞冻存稳定剂、冻存液及冻存方法 |
| WO2024141561A1 (en) * | 2022-12-28 | 2024-07-04 | Rousselot Bv | Cryopreservation formulation comprising collagen hydrolysate |
| WO2024168076A1 (en) * | 2023-02-08 | 2024-08-15 | Allen Institute | Methods of preparing and freezing biological samples for analytical use and associated compositions |
| CN116649328A (zh) * | 2023-05-10 | 2023-08-29 | 杭州中赢生物医疗科技有限公司 | 一种人类活性免疫细胞冻存液及其冻存方法 |
| WO2025019400A1 (en) * | 2023-07-14 | 2025-01-23 | Cryocrate Llc | Efficient cryopreservation medium that preserves tissue ultra-structures and eliminates tissue cells |
| CN117481109B (zh) * | 2023-12-26 | 2024-03-12 | 北京青藤谷禧干细胞科技研究院有限公司 | 一种细胞储存介质及储存方法 |
| TW202548005A (zh) * | 2024-03-01 | 2025-12-16 | 日商中央硝子股份有限公司 | 三維細胞培養體的冷凍物、包含三維細胞培養體的冷凍物的容器、細胞冷凍套件、冷凍保存液、冷凍物的製造方法、冷凍物的使用方法、三維細胞培養體之解凍物的製造方法及冷凍保存液的使用方法 |
| CN119699307B (zh) * | 2024-12-05 | 2025-10-14 | 中国农业科学院北京畜牧兽医研究所 | 蛋白质去乙酰化酶抑制剂nam在家禽精液超低温冷冻保存中的应用 |
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- 2017-10-04 WO PCT/CN2017/105252 patent/WO2018064975A1/en not_active Ceased
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| CN101220346A (zh) * | 2008-02-03 | 2008-07-16 | 西北农林科技大学 | 一种生物细胞冷冻抗冻剂 |
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| EP3534705A4 (en) | 2020-04-22 |
| EP3534705A1 (en) | 2019-09-11 |
| CN109843052A (zh) | 2019-06-04 |
| KR20190090780A (ko) | 2019-08-02 |
| TW201816107A (zh) | 2018-05-01 |
| JP2019528765A (ja) | 2019-10-17 |
| CA3036391A1 (en) | 2018-04-12 |
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