JP7157050B2 - 細胞生存率を維持するための組成物および方法 - Google Patents
細胞生存率を維持するための組成物および方法 Download PDFInfo
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- JP7157050B2 JP7157050B2 JP2019517763A JP2019517763A JP7157050B2 JP 7157050 B2 JP7157050 B2 JP 7157050B2 JP 2019517763 A JP2019517763 A JP 2019517763A JP 2019517763 A JP2019517763 A JP 2019517763A JP 7157050 B2 JP7157050 B2 JP 7157050B2
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/128—Chemically defined matrices for immobilising, holding or storing living parts, e.g. alginate gels; Chemically altering living parts, e.g. by cross-linking
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/16—Physical preservation processes
- A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0656—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Oncology (AREA)
- Developmental Biology & Embryology (AREA)
- Rheumatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662404170P | 2016-10-04 | 2016-10-04 | |
| US62/404,170 | 2016-10-04 | ||
| US201662405447P | 2016-10-07 | 2016-10-07 | |
| US62/405,447 | 2016-10-07 | ||
| PCT/CN2017/105252 WO2018064975A1 (en) | 2016-10-04 | 2017-10-04 | Compositions and methods for maintaining cell viability |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019528764A JP2019528764A (ja) | 2019-10-17 |
| JP7157050B2 true JP7157050B2 (ja) | 2022-10-19 |
Family
ID=61756821
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517763A Active JP7157050B2 (ja) | 2016-10-04 | 2017-10-04 | 細胞生存率を維持するための組成物および方法 |
| JP2019517802A Pending JP2019528765A (ja) | 2016-10-04 | 2017-10-04 | 細胞の凍結保存のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517802A Pending JP2019528765A (ja) | 2016-10-04 | 2017-10-04 | 細胞の凍結保存のための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10815456B2 (https=) |
| EP (2) | EP3523419B1 (https=) |
| JP (2) | JP7157050B2 (https=) |
| KR (2) | KR102502294B1 (https=) |
| CN (2) | CN109843052A (https=) |
| CA (2) | CA3036391A1 (https=) |
| TW (2) | TWI670371B (https=) |
| WO (2) | WO2018064975A1 (https=) |
Families Citing this family (60)
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| US10815456B2 (en) * | 2016-10-04 | 2020-10-27 | Transwell Biotech Co., Ltd. | Composition, kit and method for cryopreserving cells |
| US20220125042A1 (en) * | 2017-05-17 | 2022-04-28 | Universidade Nova De Lisboa | Cryoprotectant and/or cryopreservant composition, methods and uses thereof |
| KR102503086B1 (ko) * | 2017-09-08 | 2023-02-23 | 가부시키가이샤 오츠카 세이야쿠 고죠 | 어린 돼지 유래 줄기 세포 및 그 제조 방법 |
| JP7000212B2 (ja) * | 2018-03-14 | 2022-01-19 | 旭化成株式会社 | 幹細胞の凍結保存液 |
| CN108552158A (zh) * | 2018-04-09 | 2018-09-21 | 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) | 一种贴壁细胞冻存液、冻存方法和解冻方法 |
| CN108728408B (zh) * | 2018-05-28 | 2021-08-24 | 天津博雅秀岩生物技术有限公司 | 犬胎膜间充质干细胞及制备方法和使用的培养基 |
| DK3829604T3 (da) * | 2018-07-27 | 2025-05-19 | Cellphire Inc | Kryokonserverede blodpladesammensætninger og fremgangsmåder til fremstilling |
| EP3887404A4 (en) | 2018-11-30 | 2022-11-02 | Cellphire, Inc. | SLIDES LOADED WITH ANTI-CANCER AGENTS |
| US11767511B2 (en) | 2018-11-30 | 2023-09-26 | Cellphire, Inc. | Platelets as delivery agents |
| TWI837281B (zh) * | 2019-01-17 | 2024-04-01 | 日商長瀨產業股份有限公司 | 細胞冷凍保存液及細胞的漸凍方法 |
| US20200263128A1 (en) * | 2019-02-15 | 2020-08-20 | Michael C. Doody | In Vitro Fertilization Media with Antiviral Medicine |
| CN109792985A (zh) * | 2019-02-20 | 2019-05-24 | 华东理工大学 | 细胞冻存液 |
| WO2020207151A1 (zh) * | 2019-04-09 | 2020-10-15 | 北京大学第三医院(北京大学第三临床医学院) | 一种无dmso的冷冻保存液及其制备方法与应用 |
| JP6830294B1 (ja) * | 2019-04-26 | 2021-02-17 | 株式会社大塚製薬工場 | トレハロースを含む哺乳動物細胞保存用液 |
| CN114007416A (zh) * | 2019-04-30 | 2022-02-01 | 明尼苏达大学董事会 | 用于细胞的冷冻保存的组合物和方法 |
| AU2020267368B2 (en) | 2019-05-03 | 2023-05-04 | Cellphire, Inc. | Materials and methods for producing blood products |
| WO2020246781A1 (ko) * | 2019-06-02 | 2020-12-10 | (주)카스 인 바이오 | 연질 생체 조직을 미립자화하는 방법 및 이의 방법으로 제조된 연질 생체 조직 미립자 이식편 |
| NZ783290A (en) | 2019-06-11 | 2026-02-27 | Axogen Corp | Wet preservation of tissue |
| WO2021011857A1 (en) * | 2019-07-17 | 2021-01-21 | Cellphire, Inc. | Use of platelets in treating infections |
| EP4013496A4 (en) | 2019-08-16 | 2023-10-18 | Cellphire Inc. | THROMBOSOMES AS AN AGENT FOR REMOVING THE THROMBOCYTE AGGREGATION-INHIBITING EFFECT |
| WO2021092199A1 (en) * | 2019-11-08 | 2021-05-14 | Kansas State University Research Foundation | Isolation, preservation, and expansion of canine umbilical cord mesenchymal stromal cells |
| CN111066776A (zh) * | 2019-11-09 | 2020-04-28 | 无锡市人民医院 | 一种卵子冷冻保护剂及其应用 |
| CN114729317A (zh) | 2019-11-29 | 2022-07-08 | 新泽西鲁特格斯州立大学 | 脐带血血浆制品、组织和细胞外泌体的分离方法,其组合物及使用方法 |
| CN114786481A (zh) * | 2019-11-29 | 2022-07-22 | 新泽西鲁特格斯州立大学 | 用于储存血液制品的组合物、试剂盒和方法及其使用方法 |
| CN110934132A (zh) * | 2019-12-30 | 2020-03-31 | 苏州君欣生物科技有限公司 | 一种无血清无dmso细胞冻存液及其制备方法 |
| KR102542183B1 (ko) * | 2019-12-31 | 2023-06-14 | (주)두다 | 치아 유래 줄기세포의 분리를 위한 치아의 보존 방법 |
| CA3167649A1 (en) * | 2020-01-21 | 2021-07-29 | Takeda Pharmaceutical Company Limited | Compositions and methods of cryopreserving cells |
| CA3170201A1 (en) | 2020-02-04 | 2021-08-12 | Cellphire, Inc. | Methods of treating congenital hemophilia with anti-fibrinolytic loaded platelets |
| WO2021231806A1 (en) * | 2020-05-13 | 2021-11-18 | Rapa Therapeutics, Llc | Antigen presenting t cells, sensitized, manufactured t cells and methods of treatment using the same |
| GB202007905D0 (en) * | 2020-05-27 | 2020-07-08 | Univ Edinburgh | Cryopressing macrophages |
| EP4173483A4 (en) * | 2020-06-26 | 2024-07-17 | Mepsgen Co., Ltd. | CRYOPRESERVATION METHODS FOR ORGAN ON A CHIP |
| EP4199714B1 (en) * | 2020-08-18 | 2026-02-11 | Ichilov Tech Ltd. | Method for organ preservation |
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| US12426594B2 (en) | 2020-09-24 | 2025-09-30 | Everest Medical Innovation GmbH | Cryoprotective compositions and methods for protection of a surgical site during cryosurgery |
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| CN116472283A (zh) * | 2020-10-29 | 2023-07-21 | 国立大学法人大阪大学 | 细胞结构体的冷冻方法 |
| US20220211029A1 (en) * | 2020-11-10 | 2022-07-07 | Cellphire, Inc. | Freeze-dried peripheral blood mononuclear cell compositions and methods |
| JP7266892B2 (ja) * | 2020-11-16 | 2023-05-01 | 株式会社アビー | 細胞凍結保存液、凍結細胞保存方法、及び細胞凍結方法 |
| CN112438252B (zh) * | 2020-11-20 | 2021-06-08 | 上海欧易生物医学科技有限公司 | 一种适用于小鼠心脏组织单细胞测序的组织冷冻及解冻方法 |
| CN112616827B (zh) * | 2020-11-30 | 2022-05-13 | 中国科学技术大学 | 红细胞冻存方法及冻存的红细胞 |
| CN112649268A (zh) * | 2020-12-14 | 2021-04-13 | 四川农业大学 | 精子质膜保护剂hepes/bsa及染色液和染色方法 |
| CN112514892B (zh) * | 2020-12-25 | 2022-06-14 | 广州赛莱拉干细胞科技股份有限公司 | 一种外泌体冻存保护液及其制备方法 |
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| CN114642200B (zh) * | 2022-03-01 | 2023-03-03 | 长春科技学院 | 一种鹿茸生茸区骨膜的冷冻保存方法 |
| IL315637A (en) * | 2022-03-22 | 2024-11-01 | Univ Sorbonne | A method for preserving cells |
| CN114711225B (zh) * | 2022-03-29 | 2023-08-29 | 中国科学技术大学 | 卵泡的冷冻保存和复苏方法 |
| CN114667999A (zh) * | 2022-05-27 | 2022-06-28 | 广东先康达生物科技有限公司 | 一种免疫细胞冻存稳定剂、冻存液及冻存方法 |
| JP7818743B2 (ja) * | 2022-12-28 | 2026-02-20 | ルースロ ビーヴイ | コラーゲン加水分解物を含む凍結保存調製物 |
| EP4662469A1 (en) * | 2023-02-08 | 2025-12-17 | Allen Institute | Methods of preparing and freezing biological samples for analytical use and associated compositions |
| CN116649328A (zh) * | 2023-05-10 | 2023-08-29 | 杭州中赢生物医疗科技有限公司 | 一种人类活性免疫细胞冻存液及其冻存方法 |
| WO2025019400A1 (en) * | 2023-07-14 | 2025-01-23 | Cryocrate Llc | Efficient cryopreservation medium that preserves tissue ultra-structures and eliminates tissue cells |
| CN117481109B (zh) * | 2023-12-26 | 2024-03-12 | 北京青藤谷禧干细胞科技研究院有限公司 | 一种细胞储存介质及储存方法 |
| WO2025183063A1 (ja) * | 2024-03-01 | 2025-09-04 | セントラル硝子株式会社 | 三次元細胞培養体の凍結物、三次元細胞培養体の凍結物を含む容器、細胞凍結キット、凍結保存液、三次元細胞培養体の凍結物の製造方法、三次元細胞培養体の凍結物の使用方法、および凍結保存液の使用方法 |
| CN119699307B (zh) * | 2024-12-05 | 2025-10-14 | 中国农业科学院北京畜牧兽医研究所 | 蛋白质去乙酰化酶抑制剂nam在家禽精液超低温冷冻保存中的应用 |
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| EP3523419C0 (en) | 2025-05-14 |
| EP3534705A1 (en) | 2019-09-11 |
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| WO2018064975A1 (en) | 2018-04-12 |
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| US11485953B2 (en) | 2022-11-01 |
| US10815456B2 (en) | 2020-10-27 |
| KR20190090780A (ko) | 2019-08-02 |
| US20180094235A1 (en) | 2018-04-05 |
| KR20190088461A (ko) | 2019-07-26 |
| EP3523419A4 (en) | 2020-04-15 |
| EP3523419A1 (en) | 2019-08-14 |
| US20180092348A1 (en) | 2018-04-05 |
| JP2019528765A (ja) | 2019-10-17 |
| JP2019528764A (ja) | 2019-10-17 |
| CN109790514A (zh) | 2019-05-21 |
| TW201831876A (zh) | 2018-09-01 |
| CA3036391A1 (en) | 2018-04-12 |
| CA3036388A1 (en) | 2018-04-12 |
| EP3523419B1 (en) | 2025-05-14 |
| WO2018064976A1 (en) | 2018-04-12 |
| EP3534705A4 (en) | 2020-04-22 |
| CN109843052A (zh) | 2019-06-04 |
| TWI670371B (zh) | 2019-09-01 |
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