TR200003577T2 - Enterik kaplı farmasötik tablet ve üretim metodu - Google Patents
Enterik kaplı farmasötik tablet ve üretim metoduInfo
- Publication number
- TR200003577T2 TR200003577T2 TR2000/03577T TR200003577T TR200003577T2 TR 200003577 T2 TR200003577 T2 TR 200003577T2 TR 2000/03577 T TR2000/03577 T TR 2000/03577T TR 200003577 T TR200003577 T TR 200003577T TR 200003577 T2 TR200003577 T2 TR 200003577T2
- Authority
- TR
- Turkey
- Prior art keywords
- tablets
- coated pharmaceutical
- production method
- enteric coated
- pharmaceutical tablet
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
Abstract
ddI gibi, 3'ten daha az olan, düsük bir pH ortamina duyarli olan bir ilaçtan olusan ve tablet formundaki bir özü içeren, metakrilik asit kopolimerinden ve bir plastiklestiriciden olusan enterik kaplamaya sahip olan, yüksek ilaç yüklemeli, enterik kapli bir farmasötik kompozisyon saglanmaktadir. Bahsedilen tabletler; degisen boyutlarda olabilmekte, bireysel olarak, oral yolla mideye gönderilebilmekte veya istenen bir dozaja ulasmaya yetecek kadar olan tabletlerin bir toplulugu, çözünebilen kapsül içinde kapsüllenebilmektedir. Söz konusu tabletler; 3'ten düsük pH'de, ayrilmaya (disentegrasyona) karsi mükemmel dirence sahiptir, ancak, 4.5'ten daha büyük pH'de ise, mükemmel ilaç salinim özelliklerine sahiptirler. Bunun yaninda, bahsedilen farmasötik kompozisyonu yapmanin yeni bir metodu da bildirilmektedir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11841898A | 1998-07-17 | 1998-07-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200003577T2 true TR200003577T2 (tr) | 2001-06-21 |
Family
ID=22378467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/03577T TR200003577T2 (tr) | 1998-07-17 | 1998-08-06 | Enterik kaplı farmasötik tablet ve üretim metodu |
Country Status (35)
Country | Link |
---|---|
US (2) | US6331316B1 (tr) |
EP (1) | EP1098635B1 (tr) |
JP (1) | JP2002520350A (tr) |
KR (1) | KR100535954B1 (tr) |
CN (1) | CN1195499C (tr) |
AR (1) | AR019934A1 (tr) |
AT (1) | ATE268165T1 (tr) |
AU (1) | AU750388B2 (tr) |
BG (1) | BG65443B1 (tr) |
BR (1) | BR9815948A (tr) |
CA (1) | CA2337885C (tr) |
CO (1) | CO5090840A1 (tr) |
CZ (1) | CZ301557B6 (tr) |
DE (1) | DE69824319T2 (tr) |
DK (1) | DK1098635T3 (tr) |
EE (1) | EE05021B1 (tr) |
EG (1) | EG23944A (tr) |
ES (1) | ES2221188T3 (tr) |
GE (1) | GEP20032912B (tr) |
HU (1) | HU226492B1 (tr) |
ID (1) | ID27019A (tr) |
IL (1) | IL139701A0 (tr) |
LT (1) | LT4844B (tr) |
LV (1) | LV12638B (tr) |
NO (1) | NO330554B1 (tr) |
NZ (1) | NZ508298A (tr) |
PL (1) | PL195587B1 (tr) |
PT (1) | PT1098635E (tr) |
RO (1) | RO121082B1 (tr) |
RU (1) | RU2201217C2 (tr) |
SK (1) | SK285152B6 (tr) |
TR (1) | TR200003577T2 (tr) |
UA (1) | UA73092C2 (tr) |
WO (1) | WO2000003696A1 (tr) |
ZA (1) | ZA993446B (tr) |
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1998
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- 1998-08-06 ES ES98940790T patent/ES2221188T3/es not_active Expired - Lifetime
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- 1998-08-06 NZ NZ508298A patent/NZ508298A/en not_active IP Right Cessation
- 1998-08-06 AT AT98940790T patent/ATE268165T1/de active
- 1998-08-06 ID IDW20010105A patent/ID27019A/id unknown
- 1998-08-06 WO PCT/US1998/016323 patent/WO2000003696A1/en active IP Right Grant
- 1998-08-06 KR KR10-2001-7000742A patent/KR100535954B1/ko not_active IP Right Cessation
- 1998-08-06 RO ROA200100021A patent/RO121082B1/ro unknown
- 1998-08-06 EE EEP200100033A patent/EE05021B1/xx unknown
- 1998-08-06 TR TR2000/03577T patent/TR200003577T2/tr unknown
- 1998-08-06 CA CA002337885A patent/CA2337885C/en not_active Expired - Fee Related
- 1998-08-06 CZ CZ20010215A patent/CZ301557B6/cs not_active IP Right Cessation
- 1998-08-06 CN CNB988141736A patent/CN1195499C/zh not_active Expired - Lifetime
- 1998-08-06 DE DE69824319T patent/DE69824319T2/de not_active Expired - Lifetime
- 1998-08-06 EP EP98940790A patent/EP1098635B1/en not_active Expired - Lifetime
- 1998-08-06 RU RU2001104535/14A patent/RU2201217C2/ru active
- 1998-08-06 SK SK1883-2000A patent/SK285152B6/sk not_active IP Right Cessation
- 1998-08-06 HU HU0102659A patent/HU226492B1/hu active IP Right Revival
- 1998-08-06 PL PL98345774A patent/PL195587B1/pl unknown
- 1998-08-06 JP JP2000559831A patent/JP2002520350A/ja active Pending
- 1998-08-06 BR BR9815948-8A patent/BR9815948A/pt not_active Application Discontinuation
- 1998-08-06 PT PT98940790T patent/PT1098635E/pt unknown
- 1998-08-06 AU AU88983/98A patent/AU750388B2/en not_active Expired
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1999
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- 1999-07-03 EG EG80099A patent/EG23944A/xx active
- 1999-07-14 CO CO99044569A patent/CO5090840A1/es unknown
- 1999-07-16 AR ARP990103526A patent/AR019934A1/es not_active Application Discontinuation
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2000
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