SI9720017B - Liquid oral compositions comprising a calcium compound and an acidulant - Google Patents

Liquid oral compositions comprising a calcium compound and an acidulant Download PDF

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SI9720017B
SI9720017B SI9720017A SI9720017A SI9720017B SI 9720017 B SI9720017 B SI 9720017B SI 9720017 A SI9720017 A SI 9720017A SI 9720017 A SI9720017 A SI 9720017A SI 9720017 B SI9720017 B SI 9720017B
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composition
calcium
acid
beverage
acidulant
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SI9720017A
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SI9720017A (sl
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David Myatt Parker
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Smithkline Beecham Plc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385—Concentrates of non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/68—Acidifying substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Claims (32)

1 PATENTNI ZAHTEVKI 1. Tekoči sestavek za oralno uporabo, ki vsebuje kalcijevo spojino in acidulant, označen s tem, daje kalcij prisoten v območju od 0,3 do 0,55 mol na mol kisline in da delež kalcija in acidulanta v sestavku izberemo tako, daje pH sestavka od 3,5 do 4,5.
2. Sestavek po zahtevku 1, označen s tem, daje kalcij prisoten v količini vsaj 0,4 mol na mol kisline.
3. Sestavek po zahtevku 1 ali 2, označen s tem, da njegov pH ni večji od 4.
4. Sestavek po kateremkoli od zahtevkov 1 do 3, označen s tem, da je pH od 3,7 do 3,9.
5. Sestavek po kateremkoli od zahtevkov 1 do 4, označen s tem, daje kislina citronska ali jabolčna ali mlečna ali zmes le-teh.
6. Sestavek po kateremkoli od zahtevkov 1 do 5, označen s tem, daje kalcijeva spojina kalcijev karbonat, kalcijev hidroksid, kalcijev citrat, kalcijev malat, kalcijev laktat, kalcijev klorid, kalcijev glicerofosfat ali kalcijev formiat.
7. Sestavek po kateremkoli od zahtevkov 1 do 6, označen s tem, daje pijača.
8. Sestavek po zahtevku 7, označen s tem, da je pijača nepeneča se sadna pijača ali brezalkoholna pijača, ki vsebuje ogljikovo kislino, ali prednostno zdravilna pijača.
9. Sestavek po zahtevku 8, označen s tem, daje zdravilna pijača sok črnega ribeza ali pijača z dodanim vitaminom. 2
10. Sestavek po kateremkoli od zahtevkov 1 do 6, označen s tem, daje koncentrat za pripravo pijače.
11. Sestavek po zahtevku 10, označen s tem, da je koncentrat za sadno pijačo ali zdravilno pijačo.
12. Sestavek po kateremkoli od zahtevkov 1 do 6, označen s tem, da je sestavek za zdravstveno nego ust.
13. Sestavek po zahtevku 12, označen s tem, daje ustna voda.
14. Uporaba kalcija za izdelavo kislega tekočega sestavka, ki inhibira zobno erozijo in obsega kalcijevo spojino in acidulant, za oralno uporabo, označena s tem, da je kalcij prisoten v območju od 0,3 do 0,8 mol na mol kisline in je količina kalcija in acidulanta v sestavku izbrana tako, daje pH sestavka od 3,5 do 4,5; s pridržkom, da če je sestavek tekočina, ki vsebuje sadje in je vsebnost sadja od 25 do 100 mas.% in vsebnost kisline vsaj 5 g/1 (računano kot vinska kislina), potem le-ta vsebuje manj od 2 g/1 raztopljenega kalcijevega fosfata.
15. Uporaba kalcija za izdelavo kislega tekočega sestavka, ki inhibira zobno erozijo in obsega kalcijevo spojino in acidulant, za oralno uporabo, označena s tem, da je kalcij prisoten v območju od 0,3 do 0,55 mol na mol kisline in je količina kalcija in acidulanta v sestavku izbrana tako, daje pH sestavka od 3,5 do 4,5.
16. Uporaba po zahtevku 14 ali 15, označena s tem, daje kalcij prisoten v količini vsaj 0,4 mol na mol kisline.
17. Uporaba po zahtevku 14, 15 ali 16, označena s tem, da pH sestavka ni večji od 4.
18. Uporaba po kateremkoli od zahtevkov 14 do 17, označena s tem, daje pH sestavka od 3,7 do 3,9. 3
19. Uporaba po kateremkoli od zahtevkov 14 do 18, označena s tem, daje kisli tekoči sestavek pijača.
20. Uporaba po zahtevku 19, označena s tem, daje pijača nepeneča se sadna pijača, brezalkoholna pijača, ki vsebuje ogljikovo kislino, ali zdravilna pijača.
21. Uporaba po kateremkoli od zahtevkov 14 do 18, označena s tem, daje kisli tekoči sestavek koncentrat za pripravo pijače.
22. Uporaba po zahtevku 21, označena s tem, da je koncentrat za sadno pijačo ali zdravilno pijačo.
23. Postopek za pripravo tekočega sestavka za oralno uporabo, ki vsebuje kalcijevo spojino in acidulant, označen s tem, daje kalcij prisoten v območju od 0,3 do 0,8 mol na mol kisline in je pH sestavka od 3,5 do 4,5 in obsega mešanje kalcijeve spojine z acidulantom, tako da je kalcij prisoten v območju od 0,3 do 0,8 mol na mol kisline, naravnavanje pH, če je potrebno ali želeno, z dodatkom alkalije, tako da je pH sestavka v območju od 3,5 do 4,5; s pridržkom, da če je sestavek tekočina, ki vsebuje sadje in je vsebnost sadja od 25 do 100 mas.% in vsebnost kisline vsaj 5 g/I (računano kot vinska kislina), potem le-ta vsebuje manj od 2 g/1 raztopljenega kalcijevega fosfata.
24. Postopek za pripravo sestavka po kateremkoli od zahtevkov 1 do 13, označen s tem, da obsega mešanje kalcijeve spojine z acidulantom, tako da je kalcij prisoten v območju od 0,3 do 0,55 mol na mol kisline in je pH sestavka od 3,5 do 4,5, naravnavanje pH, če je potrebno ali želeno, z dodatkom alkalije, tako da je pH v območju od 3,5 do 4,5.
25. Postopek po zahtevku 23 ali 24, označen s tem, daje kisli tekoči sestavek pijača. 4
26. Postopek po zahtevku 25, označen s tem, da je pijača nepeneča se sadna pijača, brezalkoholna pijača, ki vsebuje ogljikovo kislino, ali zdravilna pijača.
27. Postopek po zahtevku 23 ali 24, označen s tem, da je kisli tekoči sestavek koncentrat za pripravo pijače.
28. Postopek po zahtevku 27, označen s tem, da je koncentrat za sadno pijačo ali zdravilno pijačo.
29. Postopek za zmanjševanje zobnih erozijskih lastnosti kislega oralnega sestavka, označen s tem, da obsega dodajanje kalcija v kisli tekoči oralni sestavek, tako da je kalcij prisoten v območju od 0,3 do 0,8 mol na mol kisline in je pH sestavka od 3,5 do 4,5, naravnavanje pH, če je potrebno ali želeno, z dodatkom alkalije, tako da je pH od 3,5 do 4,5; s pridržkom, da če je sestavek tekočina, ki vsebuje sadje in ima vsebnost sadja od 25 do 100 mas.% in vsebnost kisline vsaj 5 g/1 (računano kot vinska kislina), potem le-ta vsebuje manj od 2 g/1 raztopljenega kalcijevega fosfata.
30. Postopek za zmanjševanje zobnih erozijskih lastnosti kislega oralnega sestavka, označen s tem, da obsega dodajanje kalcija v kisli tekoči oralni sestavek, tako da je kalcij prisoten v območju od 0,3 do 0,55 mol na mol kisline in je pH sestavka od 3,5 do 4,5, naravnavanje pH, če je potrebno ali želeno, z dodatkom alkalije, tako daje pH v območju od 3,5 do 4,5.
31. Uporaba tekočega sestavka, ki obsega kalcijevo spojino in acidulant, pri izdelavi sestavka za oralno dajanje za zmanjšanje zobne erozije, povzročene s kislino, označena s tem, da je kalcij prisoten v sestavku v območju od 0,3 do 0,8 mol na mol kisline in je količina kalcija in acidulanta v sestavku izbrana tako, da je pH sestavka od 3,5 do 4,5; s pridržkom, da če je sestavek tekočina, ki vsebuje sadje in je vsebnost sadja od 25 do 100 mas.% in vsebnost kisline vsaj 5 g/1 (računano kot vinska kislina), potem le-ta vsebuje manj od 2 g/1 raztopljenega kalcijevega fosfata. 5
32. Uporaba tekočega sestavka, ki obsega kalcijevo spojino in acidulant, pri izdelavi sestavka za oralno dajanje za zmanjšanje zobne erozije, povzročene s kislino, označena s tem, daje kalcij prisoten v sestavku v območju od 0,3 do 0,55 mol na mol kisline in je količina kalcija in acidulanta v sestavku izbrana tako, daje pH sestavka od 3,5 do 4,5.
SI9720017A 1996-02-20 1997-02-12 Liquid oral compositions comprising a calcium compound and an acidulant SI9720017B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9603518.3A GB9603518D0 (en) 1996-02-20 1996-02-20 Novel process
PCT/EP1997/000646 WO1997030601A1 (en) 1996-02-20 1997-02-12 Liquid oral compositions comprising a calcium compound and an acidulant

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Publication Number Publication Date
SI9720017A SI9720017A (sl) 1999-06-30
SI9720017B true SI9720017B (en) 2001-12-31

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SI9720017A SI9720017B (en) 1996-02-20 1997-02-12 Liquid oral compositions comprising a calcium compound and an acidulant

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US (4) US6319490B1 (sl)
EP (2) EP1382263B1 (sl)
JP (2) JPH11507842A (sl)
KR (1) KR100301344B1 (sl)
CN (1) CN1149021C (sl)
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AU (1) AU719631B2 (sl)
BG (1) BG64364B1 (sl)
BR (1) BR9707618A (sl)
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CZ (1) CZ297770B6 (sl)
DE (3) DE69736683T2 (sl)
DK (2) DK0874558T3 (sl)
EA (2) EA002852B1 (sl)
ES (2) ES2208873T3 (sl)
FI (1) FI981781A0 (sl)
GB (2) GB9603518D0 (sl)
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IL (1) IL125725A (sl)
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MY (1) MY121660A (sl)
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NZ (1) NZ331363A (sl)
PL (2) PL191418B1 (sl)
PT (2) PT1382263E (sl)
RO (1) RO121001B1 (sl)
SA (1) SA97180011B1 (sl)
SE (2) SE521489C2 (sl)
SI (1) SI9720017B (sl)
SK (1) SK285049B6 (sl)
TR (1) TR199801623T2 (sl)
TW (1) TW592705B (sl)
UA (1) UA61903C2 (sl)
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