RU2017126046A - Шприц для удерживания и смешивания первого и второго веществ - Google Patents
Шприц для удерживания и смешивания первого и второго веществ Download PDFInfo
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- RU2017126046A RU2017126046A RU2017126046A RU2017126046A RU2017126046A RU 2017126046 A RU2017126046 A RU 2017126046A RU 2017126046 A RU2017126046 A RU 2017126046A RU 2017126046 A RU2017126046 A RU 2017126046A RU 2017126046 A RU2017126046 A RU 2017126046A
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- plunger
- chamber
- syringe according
- vacuum chamber
- valve
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
- A61B2017/00495—Surgical glue applicators for two-component glue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Claims (31)
1. Шприц для удерживания и смешивания первого и второго веществ, содержащий:
- цилиндр, содержащий уплотняемое и/или закрываемое дистальное выпускное отверстие и вакуумную камеру для вмещения первого вещества,
- плунжер, предназначенный для уплотняемого сопряжения внутри цилиндра и выполненный с возможностью аксиального смещения относительно вакуумной камеры, при этом плунжер включает камеру-емкость для вмещения второго вещества; и
- клапан, разделяющий вакуумную камеру внутри цилиндра и камеру-емкость внутри плунжера, причем клапан предназначен для управления соединением по текучей среде между камерой-емкостью и вакуумной камерой и/или установления данного соединения,
причем шприц выполнен таким образом, что
в первой конфигурации, соответствующей первому зафиксированному аксиальному положению плунжера внутри цилиндра, первое вещество удерживается в условиях вакуума в вакуумной камере,
а во второй конфигурации плунжер откреплен, и вакуум в вакуумной камере втягивает плунжер в дистальном направлении таким образом, что клапан задействуется для обеспечения проточного канала между камерой-емкостью и вакуумной камерой.
2. Шприц по п. 1, в котором шприц предварительно заполнен первым и вторым веществами, причем первое вещество является сухой композицией, являющейся вакуумно-вспененной, сублимационно-высушенной пастой, а второе вещество является водной средой, выбранной из воды, физиологического раствора, раствора кальция хлорида или буферного водного раствора.
3. Шприц по п. 2, в котором сублимационно-высушенная паста содержит тромбин.
4. Шприц по любому из предшествующих пунктов, в котором клапан расположен в дистальном конце плунжера.
5. Шприц по любому из предшествующих пунктов, выполненный таким образом, что плунжер заблокирован от аксиального смещения в дистальном направлении в указанной первой конфигурации.
6. Шприц по п. 5, в котором плунжер заблокирован от аксиального смещения в дистальном направлении в указанной первой конфигурации посредством открепляемого фиксирующего элемента для зацепления и фиксации плунжера в указанной первой конфигурации.
7. Шприц по п. 5, в котором фиксирующий элемент выполнен с возможностью открепляемого прикрепления к части плунжера, которая проходит от проксимального конца цилиндра.
8. Шприц по любому из пп. 4-6, выполненный таким образом, что, после открепления плунжера, вакуум в вакуумной камере вынуждает аксиальное смещение плунжера из первого положения во второе положение.
9. Шприц по любому из предшествующих пунктов, выполненный таким образом, что аксиальное смещение плунжера из первого положения во второе положение переводит клапан из закрытой конфигурации клапана в первом положении в открытую конфигурацию клапана во втором положении для установления проточного канала между камерой-емкостью и вакуумной камерой.
10. Шприц по п. 9, выполненный таким образом, что, после выпуска второго вещества из камеры-емкости в вакуумную камеру, клапан переводится из открытой конфигурации клапана в закрытую конфигурацию клапана, с блокированием, тем самым, проточного канала между камерой-емкостью и вакуумной камерой.
11. Шприц по любому из предшествующих пунктов, дополнительно содержащий пробку внутри плунжера, который является полым, и уплотняемым образом сопряженную с ним так, что камера-емкость ограничена пробкой внутри полого плунжера.
12. Шприц по п. 11, в котором пробка целиком содержится внутри полого корпуса плунжера.
13. Шприц по любому из пп. 11-12, в котором пробка утоплена внутри полого корпуса плунжера.
14. Шприц по любому из пп. 11-13, в котором пробка выполнена с возможностью аксиального смещения в дистальном направлении внутри полого корпуса плунжера во время высвобождения/выпуска второго вещества из камеры-емкости в вакуумную камеру.
15. Шприц по п. 14, в котором пробка и клапан выполнены таким образом, что пробка задействует и закрывает клапан, при достижении дистального конца плунжера после выпуска второго вещества из камеры-емкости.
16. Шприц по любому из предшествующих пунктов, выполненный таким образом, что первое вещество, расположенное в вакуумной камере, может задействовать клапан, при контакте между клапаном и первым веществом, во время аксиального смещения плунжера к дистальному концу цилиндра, для установления проточного канала между камерой-емкостью и вакуумной камерой.
17. Шприц по любому из пп. 9-16, в котором клапан содержит, по меньшей мере, один аксиально смещаемый элемент, при этом открытая конфигурация клапана соответствует первому положению указанного аксиально смещаемого элемента, а закрытая конфигурация клапана соответствует второму положению указанного аксиально смещаемого элемента.
18. Шприц по п. 17, в котором клапан выполнен таким образом, что указанный аксиально смещаемый элемент выступает в вакуумную камеру в указанном первом положении и выступает в камеру-емкость в указанном втором положении.
19. Шприц по любому из пп. 17-18, в котором указанный аксиально смещаемый элемент на дистальном конце содержит плоскую поджимную поверхность (дистальную поверхность), проходящую в вакуумную камеру, при этом указанная плоская поверхность образует плоскость, перпендикулярную продольной оси шприца.
20. Шприц по любому из пп. 17-19, в котором аксиально смещаемый элемент выполнен таким образом, что клапан остается в открытой конфигурации, когда указанный аксиально смещаемый элемент смещается в проксимальном направлении.
21. Шприц по любому из пп. 17-20, выполненный таким образом, что пробка внутри плунжера зацепляет указанный аксиально смещаемый элемент и смещает его в дистальном направлении, с закрыванием, тем самым, клапана, при достижении дистального конца плунжера после выпуска второго вещества из камеры-емкости.
22. Шприц по любому из предшествующих пунктов, дополнительно содержащий один или более перепускных вакуумных каналов, расположенных в цилиндре и/или в плунжере и выполненных таким образом, что плунжер уплотняемым образом сопряжен с вакуумной камерой в, по меньшей мере, первом аксиальном положении плунжера внутри вакуумной камеры, и таким образом, что сообщение по текучей среде установлено через плунжер в, по меньшей мере, втором аксиальном положении плунжера внутри вакуумной камеры через указанный один или более перепускных вакуумных каналов.
23. Шприц по п. 22, в котором указанный один или более перепускных вакуумных каналов выполнены с возможностью нарушения уплотнения между вакуумной камерой и плунжером в заданном аксиальном положении плунжера внутри вакуумной камеры.
24. Шприц по любому из предшествующих пунктов, в котором первая конфигурация является состоянием хранения шприца.
25. Шприц по любому из предшествующих пунктов, выполненный таким образом, что вакуум может создаваться в вакуумной камере в заданной конфигурации шприца посредством внешнего вакуум-генераторного средства.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14200323 | 2014-12-24 | ||
| EP14200323.5 | 2014-12-24 | ||
| PCT/EP2015/080761 WO2016102446A1 (en) | 2014-12-24 | 2015-12-21 | Syringe for retaining and mixing first and second substances |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2017126046A true RU2017126046A (ru) | 2019-01-25 |
| RU2017126046A3 RU2017126046A3 (ru) | 2019-05-23 |
| RU2705905C2 RU2705905C2 (ru) | 2019-11-12 |
Family
ID=52146342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017126046A RU2705905C2 (ru) | 2014-12-24 | 2015-12-21 | Шприц для удерживания и смешивания первого и второго веществ |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10653837B2 (ru) |
| EP (1) | EP3237041B1 (ru) |
| JP (1) | JP6747650B2 (ru) |
| CN (1) | CN107206165B (ru) |
| AU (1) | AU2015371184B2 (ru) |
| BR (1) | BR112017013565B1 (ru) |
| CA (1) | CA2970710A1 (ru) |
| HK (1) | HK1243365A1 (ru) |
| RU (1) | RU2705905C2 (ru) |
| WO (1) | WO2016102446A1 (ru) |
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| BR112014030962A2 (pt) | 2012-06-12 | 2017-06-27 | Ferrosan Medical Devices As | métodos para preparação e para reconstituição de uma composição seca adequada para uso em hemostase e cicatrização de feridas, e, kit hemostático |
| RU2700162C2 (ru) | 2013-06-21 | 2019-09-13 | Ферросан Медикал Дивайсиз А/С | Расширенная под вакуумом сухая композиция и шприц для ее сохранения |
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| CA2960309A1 (en) | 2014-10-13 | 2016-04-21 | Ferrosan Medical Devices A/S | Dry composition for use in haemostasis and wound healing |
| AU2016290433B2 (en) | 2015-07-03 | 2018-05-24 | Ferrosan Medical Devices A/S | Syringe for mixing two components and for retaining a vacuum in a storage condition |
| GB2556088A (en) * | 2016-11-18 | 2018-05-23 | Owen Mumford Ltd | Packaging and devices for mixing medicament substances |
| CN107028762B (zh) * | 2017-05-27 | 2023-09-15 | 南京云科芝生健康科技有限公司 | 一种定量配比输液袋 |
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| US11331431B2 (en) | 2018-11-24 | 2022-05-17 | Gemini Medical, Inc. | Syringe for injecting medication with openable and closable stopper |
| CN109668873B (zh) * | 2018-12-05 | 2021-03-16 | 山东恒业生物技术有限公司 | 一种活载体疫苗活性检测装置及其使用方法 |
| IL272145A (en) * | 2020-01-20 | 2021-07-29 | Stem Cell Medicine Ltd | Cosmetic preparations with protein concentrate from a conditioned growth medium of stem cells from adipose tissue |
| CN111840763A (zh) * | 2020-08-18 | 2020-10-30 | 上海微创医疗器械（集团）有限公司 | 一种液体输送装置及治疗装置 |
| WO2022068893A1 (zh) * | 2020-09-30 | 2022-04-07 | 广州迈普再生医学科技股份有限公司 | 医用胶喷涂装置 |
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- 2015-12-21 US US15/534,801 patent/US10653837B2/en active Active
- 2015-12-21 WO PCT/EP2015/080761 patent/WO2016102446A1/en active Application Filing
- 2015-12-21 EP EP15813856.0A patent/EP3237041B1/en active Active
- 2015-12-21 RU RU2017126046A patent/RU2705905C2/ru active
- 2015-12-21 AU AU2015371184A patent/AU2015371184B2/en active Active
-
2018
- 2018-02-28 HK HK18102931.8A patent/HK1243365A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2705905C2 (ru) | 2019-11-12 |
| AU2015371184B2 (en) | 2020-06-25 |
| WO2016102446A1 (en) | 2016-06-30 |
| JP2018503425A (ja) | 2018-02-08 |
| CN107206165A (zh) | 2017-09-26 |
| BR112017013565B1 (pt) | 2021-12-28 |
| JP6747650B2 (ja) | 2020-08-26 |
| CN107206165B (zh) | 2020-10-23 |
| AU2015371184A1 (en) | 2017-07-13 |
| BR112017013565A2 (pt) | 2018-03-06 |
| US20180264194A1 (en) | 2018-09-20 |
| HK1243365A1 (zh) | 2018-07-13 |
| RU2017126046A3 (ru) | 2019-05-23 |
| EP3237041B1 (en) | 2020-01-29 |
| CA2970710A1 (en) | 2016-06-30 |
| US10653837B2 (en) | 2020-05-19 |
| EP3237041A1 (en) | 2017-11-01 |
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