RS55546B1 - Hinazolinoni kao inhibitori humane fosfatidilonozitol 3-delta kinaze - Google Patents

Hinazolinoni kao inhibitori humane fosfatidilonozitol 3-delta kinaze

Info

Publication number
RS55546B1
RS55546B1 RS20161005A RSP20161005A RS55546B1 RS 55546 B1 RS55546 B1 RS 55546B1 RS 20161005 A RS20161005 A RS 20161005A RS P20161005 A RSP20161005 A RS P20161005A RS 55546 B1 RS55546 B1 RS 55546B1
Authority
RS
Serbia
Prior art keywords
phosphatidylonositol
hinazolinons
human
kinase inhibitors
delta kinase
Prior art date
Application number
RS20161005A
Other languages
English (en)
Serbian (sr)
Inventor
Kerry W Fowler
Danwen Huang
Edward A Kesicki
Hua Chee Ooi
Amy R Oliver
Fuqiang Ruan
Jennifer Treiberg
Kamal Deep Puri
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34969603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS55546(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Icos Corp filed Critical Icos Corp
Publication of RS55546B1 publication Critical patent/RS55546B1/sr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
RS20161005A 2004-05-13 2005-05-12 Hinazolinoni kao inhibitori humane fosfatidilonozitol 3-delta kinaze RS55546B1 (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57078404P 2004-05-13 2004-05-13

Publications (1)

Publication Number Publication Date
RS55546B1 true RS55546B1 (sr) 2017-05-31

Family

ID=34969603

Family Applications (2)

Application Number Title Priority Date Filing Date
RS20161005A RS55546B1 (sr) 2004-05-13 2005-05-12 Hinazolinoni kao inhibitori humane fosfatidilonozitol 3-delta kinaze
RS20161180A RS55551B1 (sr) 2004-05-13 2005-05-12 Hinazolinoni kao inhibitori humane fosfatidilinozitol 3-kinaze delta

Family Applications After (1)

Application Number Title Priority Date Filing Date
RS20161180A RS55551B1 (sr) 2004-05-13 2005-05-12 Hinazolinoni kao inhibitori humane fosfatidilinozitol 3-kinaze delta

Country Status (23)

Country Link
US (14) USRE44638E1 (OSRAM)
EP (4) EP3943494A1 (OSRAM)
JP (1) JP2007537291A (OSRAM)
CN (2) CN102229609A (OSRAM)
AU (2) AU2005245875C1 (OSRAM)
BE (1) BE2017C002I2 (OSRAM)
CA (1) CA2566609C (OSRAM)
CY (3) CY2016046I1 (OSRAM)
DK (2) DK1761540T3 (OSRAM)
ES (3) ES2605792T3 (OSRAM)
FR (1) FR17C1007I2 (OSRAM)
HR (2) HRP20161751T1 (OSRAM)
HU (3) HUE030839T2 (OSRAM)
IL (4) IL179176A (OSRAM)
LT (3) LT2612862T (OSRAM)
LU (1) LUC00005I2 (OSRAM)
ME (2) ME02688B (OSRAM)
NL (1) NL300867I2 (OSRAM)
PL (3) PL3153514T3 (OSRAM)
PT (3) PT1761540T (OSRAM)
RS (2) RS55546B1 (OSRAM)
SI (2) SI2612862T1 (OSRAM)
WO (2) WO2005113554A2 (OSRAM)

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CA2730540A1 (en) * 2004-05-13 2005-12-01 Vanderbilt University Phosphoinositide 3-kinase delta selective inhibitors for inhibiting angiogenesis
CN102229609A (zh) 2004-05-13 2011-11-02 艾科斯有限公司 作为人磷脂酰肌醇3-激酶δ抑制剂的喹唑啉酮
US9512125B2 (en) 2004-11-19 2016-12-06 The Regents Of The University Of California Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
EP1885356A2 (en) * 2005-02-17 2008-02-13 Icos Corporation Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
GB2431156A (en) * 2005-10-11 2007-04-18 Piramed Ltd 1-cyclyl-3-substituted- -benzenes and -azines as inhibitors of phosphatidylinositol 3-kinase
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US20200017503A1 (en) 2020-01-16
DK1761540T3 (en) 2016-11-21
CY1118516T1 (el) 2017-07-12
AU2005245875C1 (en) 2017-08-31
ES2605792T3 (es) 2017-03-16
FR17C1007I1 (fr) 2017-04-21
NL300867I2 (OSRAM) 2017-05-09
LUC00005I1 (OSRAM) 2017-02-21
EP3153514B1 (en) 2021-04-21
PL1761540T3 (pl) 2017-06-30
US10336756B2 (en) 2019-07-02
US9149477B2 (en) 2015-10-06
HUS1700006I1 (hu) 2017-03-28
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US20160075705A1 (en) 2016-03-17
US20210332047A1 (en) 2021-10-28
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ES2873875T3 (es) 2021-11-04
HRP20161751T1 (hr) 2017-04-07
US20140121224A1 (en) 2014-05-01
US20100256168A1 (en) 2010-10-07
PL3153514T3 (pl) 2022-01-10
RS55551B1 (sr) 2017-05-31
WO2005113554A3 (en) 2006-04-06
US20140378479A1 (en) 2014-12-25
US20080275067A1 (en) 2008-11-06
EP3943494A1 (en) 2022-01-26
ME02688B (me) 2017-10-20
EP1761540B1 (en) 2016-09-28
FR17C1007I2 (fr) 2018-03-23
JP2007537291A (ja) 2007-12-20
LTPA2017004I1 (lt) 2017-03-10
US8779131B2 (en) 2014-07-15
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EP1761540A1 (en) 2007-03-14
IL281945A (en) 2021-05-31
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AU2009230739A1 (en) 2009-11-12
CY2016046I1 (el) 2017-11-14
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IL179176A (en) 2015-10-29
PT3153514T (pt) 2021-06-25
US10906907B2 (en) 2021-02-02
WO2005113554A2 (en) 2005-12-01
HUE030950T2 (en) 2017-06-28
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AU2005245875B2 (en) 2009-07-30
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IL269976B (en) 2021-04-29
IL179176A0 (en) 2007-03-08
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US20100256167A1 (en) 2010-10-07
US20120015964A1 (en) 2012-01-19
EP2612862A3 (en) 2014-01-08
US7932260B2 (en) 2011-04-26
US8993583B2 (en) 2015-03-31
ES2607804T3 (es) 2017-04-04
US8207153B2 (en) 2012-06-26
ME02695B (me) 2017-10-20
WO2005113556A1 (en) 2005-12-01
AU2005245875A1 (en) 2005-12-01
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US20130116266A1 (en) 2013-05-09
US20140121223A1 (en) 2014-05-01
CY1118493T1 (el) 2017-07-12
CA2566609A1 (en) 2005-12-01
DK2612862T3 (en) 2016-12-05
USRE44638E1 (en) 2013-12-10
LTC1761540I2 (lt) 2019-04-10
PT1761540T (pt) 2016-12-07
SI3153514T1 (sl) 2022-02-28
PT2612862T (pt) 2016-12-15

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