NZ575452A - Compositions and methods for coating medical implants such as vascular grafts, catheters, pacemakers etc - Google Patents

Info

Publication number

NZ575452A

NZ575452A NZ575452A NZ57545203A NZ575452A NZ 575452 A NZ575452 A NZ 575452A NZ 575452 A NZ575452 A NZ 575452A NZ 57545203 A NZ57545203 A NZ 57545203A NZ 575452 A NZ575452 A NZ 575452A

Authority

NZ

New Zealand

Prior art keywords

medical implant

catheter

implant

drug

use according

Prior art date

2002-05-24

Links

• Espacenet
• Global Dossier
• Discuss

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• 239000000203 mixture Substances 0.000 title claims abstract description 116
• 230000002792 vascular Effects 0.000 title claims abstract description 75
• 238000000576 coating method Methods 0.000 title claims description 228
• 239000011248 coating agent Substances 0.000 title claims description 187
• 238000000034 method Methods 0.000 title claims description 55
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• 229960000961 floxuridine Drugs 0.000 claims abstract description 51
• 229920000642 polymer Polymers 0.000 claims description 337
• GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical compound FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 claims description 157
• 229960002949 fluorouracil Drugs 0.000 claims description 150
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• 239000004814 polyurethane Substances 0.000 claims description 51
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• 238000001631 haemodialysis Methods 0.000 claims description 40
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• NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 24
• 230000001684 chronic effect Effects 0.000 claims description 21
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• CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 claims description 14
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